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LRRTM1 Gene

protein-coding   GIFtS: 56
GCID: GC02M080427

Leucine Rich Repeat Transmembrane Neuronal 1

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Leucine Rich Repeat Transmembrane Neuronal 11 2
Leucine-Rich Repeat Transmembrane Neuronal 1 Protein2
Leucine-Rich Repeat Transmembrane Neuronal Protein 12

External Ids:    HGNC: 194081   Entrez Gene: 3477302   Ensembl: ENSG000001629517   OMIM: 6108675   UniProtKB: Q86UE63   

Export aliases for LRRTM1 gene to outside databases

Previous GC identifers: GC02U900202 GC02M080490 GC02M080499 GC02M080382 GC02M080264


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for LRRTM1 Gene:
LRRTM1 (leucine rich repeat transmembrane neuronal 1) is a protein-coding gene. Diseases associated with LRRTM1 include autism spectrum disorder, and neuronitis. An important paralog of this gene is GP5.

UniProtKB/Swiss-Prot: LRRT1_HUMAN, Q86UE6
Function: Exhibits strong synaptogenic activity, restricted to excitatory presynaptic differentiation, acting at
both pre- and postsynaptic level (By similarity)

Gene Wiki entry for LRRTM1 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000002.12  NT_022184.16  NC_018913.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the LRRTM1 gene promoter:
         Pbx1a   Pax-2   AP-4   Pax-2a   C/EBPalpha   E47   COMP1   Zic1   Hand1   TGIF   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidLRRTM1 promoter sequence
   Search Chromatin IP Primers for LRRTM1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat LRRTM1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2p12   Ensembl cytogenetic band:  2p12   HGNC cytogenetic band: 2p12

LRRTM1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
LRRTM1 gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02M080427:  view genomic region     (about GC identifiers)

Start:
80,515,483 bp from pter      End:
80,531,874 bp from pter
Size:
16,392 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: LRRT1_HUMAN, Q86UE6 (See protein sequence)
Recommended Name: Leucine-rich repeat transmembrane neuronal protein 1 precursor  
Size: 522 amino acids; 58641 Da
Miscellaneous: This gene is imprinted, being predominantly expressed from the paternal allele and showing a
variable pattern of maternal down-regulation. May be associated paternally with handedness and schizophrenia
Secondary accessions: A8K397 D6W5K1 Q96DN1

Explore the universe of human proteins at neXtProt for LRRTM1: NX_Q86UE6

Explore proteomics data for LRRTM1 at MOPED

Post-translational modifications: 

  • Glycosylation2 at Asn56, Asn63, Asn130, Asn380

  • See LRRTM1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_849161.2  
    ENSEMBL proteins: 
     ENSP00000393562   ENSP00000414523   ENSP00000295057   ENSP00000386646   ENSP00000415368  
     ENSP00000389473   ENSP00000404557  

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    Cloud-Clone Corp. Proteins for LRRTM1

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    3 InterPro protein domains:
     IPR001611 Leu-rich_rpt
     IPR003591 Leu-rich_rpt_typical-subtyp
     IPR000372 LRR-contain_N

    Graphical View of Domain Structure for InterPro Entry Q86UE6

    ProtoNet protein and cluster: Q86UE6

    1 Blocks protein domain: IPB000372 Cysteine-rich flanking region

    UniProtKB/Swiss-Prot: LRRT1_HUMAN, Q86UE6
    Similarity: Belongs to the LRRTM family
    Similarity: Contains 10 LRR (leucine-rich) repeats
    Similarity: Contains 1 LRRCT domain
    Similarity: Contains 1 LRRNT domain


    LRRTM1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: LRRT1_HUMAN, Q86UE6
    Function: Exhibits strong synaptogenic activity, restricted to excitatory presynaptic differentiation, acting at
    both pre- and postsynaptic level (By similarity)

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003674molecular_function ND--
    GO:0005515protein binding ----
         
    LRRTM1 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for LRRTM1:
     Decreased viability with pacli 

         4 MGI mutant phenotypes (inferred from 2 alleles(MGI details for Lrrtm1):
     behavior/neurological  homeostasis/metabolism  nervous system  normal 

    LRRTM1 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-outs for LRRTM1: Lrrtm1tm1Amcr Lrrtm1tm1.1Jaru

       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for LRRTM1
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       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for LRRTM1

    miRNA
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    miRTarBase miRNAs that target LRRTM1:
    hsa-mir-9-5p (MIRT021433)

    Block miRNA regulation of human, mouse, rat LRRTM1 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate LRRTM1 (see all 21):
    hsa-miR-320a hsa-miR-3607-3p hsa-miR-520d-5p hsa-miR-1263 hsa-miR-10b* hsa-miR-499-5p hsa-miR-641 hsa-miR-208b
    SwitchGear 3'UTR luciferase reporter plasmidLRRTM1 3' UTR sequence
    Inhib. RNA
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for LRRTM1


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    LRRT1_HUMAN, Q86UE6: Cell membrane; Single-pass type I membrane protein (By similarity). Cell junction, synapse,
    postsynaptic cell membrane; Single-pass type I membrane protein (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    endoplasmic reticulum5
    plasma membrane5
    extracellular1
    lysosome1
    peroxisome1

    Gene Ontology (GO): Selected cellular component terms (see all 8):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005783endoplasmic reticulum IDA17667961
    GO:0009986NOT cell surface IDA17667961
    GO:0016021integral component of membrane IEA--
    GO:0030054cell junction IEA--
    GO:0030424axon IDA17667961

    LRRTM1 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for LRRTM1
    Interactions:

        Search GeneGlobe Interaction Network for LRRTM1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 19)

    Selected Interacting proteins for LRRTM1 (Q86UE62, 3 ENSP000002950574) via UniProtKB, MINT, STRING, and/or I2D (see all 21)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    DLG4P783523I2D: score=1 
    BOCENSP000003475464STRING: ENSP00000347546
    EPYCENSP000002611724STRING: ENSP00000261172
    HAPLN2ENSP000002550394STRING: ENSP00000255039
    LRRTM2ENSP000002747114STRING: ENSP00000274711
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007610behavior ----
    GO:0007626locomotory behavior IEA--
    GO:0008150biological_process ND--
    GO:0035418protein localization to synapse IEA--
    GO:0035640exploration behavior IEA--

    LRRTM1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for LRRTM1 (LRRT1)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for LRRTM1 gene: 
    NM_178839.4  

    Unigene Cluster for LRRTM1:

    Leucine rich repeat transmembrane neuronal 1
    Hs.591580  [show with all ESTs]
    Unigene Representative Sequence: AK225779
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000417012(uc002soj.3) ENST00000433224 ENST00000295057(uc002sok.1)
    ENST00000409148 ENST00000416268 ENST00000452811 ENST00000415098
    miRNA
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    Selected qRT-PCR Assays for microRNAs that regulate LRRTM1 (see all 21):
    hsa-miR-320a hsa-miR-3607-3p hsa-miR-520d-5p hsa-miR-1263 hsa-miR-10b* hsa-miR-499-5p hsa-miR-641 hsa-miR-208b
    SwitchGear 3'UTR luciferase reporter plasmidLRRTM1 3' UTR sequence
    Inhib. RNA
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    GenScript: all cDNA clones in your preferred vector: LRRTM1 (NM_178839)
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    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat LRRTM1
      QuantiTect SYBR Green Assays in human, mouse, rat LRRTM1
      QuantiFast Probe-based Assays in human, mouse, rat LRRTM1

    Additional mRNA sequence: 

    AK225779.1 AK290512.1 AY182024.1 

    4 DOTS entries:

    DT.40255073  DT.404294  DT.97785886  DT.120944132 

    Selected AceView cDNA sequences (see all 25):

    BI756350 BC045113 AA120980 AK056644 AY182024 AY358310 BX099213 BU146327 
    BI196715 AA297722 NM_178839 BI196253 BM546582 AA977181 BQ130417 AA122209 
    BE551640 AF114075 AI696222 BI711650 W19772 CK820495 AV721154 AV724147 

    GeneLoc Exon Structure

    2 Alternative Splicing Database (ASD) splice patterns (SP) for LRRTM1    About this scheme

    ExUns: 1a · 1b ^ 2a · 2b
    SP1:                        
    SP2:                        


    ECgene alternative splicing isoforms for LRRTM1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    LRRTM1 expression in normal human tissues (normalized intensities)      LRRTM1 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CGCTACCAAA
    LRRTM1 Expression
    About this image


    LRRTM1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 10) fully expand
     
     Kidney (Urinary System)    fully expand to see all 3 entries
             Ureteric Bud Cells Ureteric Bud
             Metanephros
     
     Neural Tube (Nervous System)    fully expand to see all 3 entries
             Metencephalon
     
     Brain (Nervous System)    fully expand to see all 3 entries
             Cerebral Cortex
     
     Gut Tube (Gastrointestinal Tract)
             Foregut
     
     NULL (Uncategorized)
             Mesoderm-like cells
    LRRTM1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    LRRTM1 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.591580

    UniProtKB/Swiss-Prot: LRRT1_HUMAN, Q86UE6
    Tissue specificity: Predominantly expressed in forebrain regions including thalamus and cerebral cortex

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for LRRTM1 gene from Selected species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Lrrtm11 , 5 leucine rich repeat transmembrane neuronal 11, 5 92.19(n)1
    97.31(a)1
      6 (33.89 cM)5
    743421  NM_028880.31  NP_083156.21 
     772426895 
    chicken
    (Gallus gallus)
    Aves LRRTM11 leucine rich repeat transmembrane neuronal 1 79.21(n)
    83.11(a)
      771502  XM_004936273.1  XP_004936330.1 
    lizard
    (Anolis carolinensis)
    Reptilia LRRTM16
    leucine rich repeat transmembrane neuronal 1
    85(a)
    1 ↔ 1
    5(149918756-149920324)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia lrrtm11 leucine rich repeat transmembrane neuronal 1 74.97(n)
    79.73(a)
      100493874  XM_002935479.2  XP_002935525.1 
    zebrafish
    (Danio rerio)
    Actinopterygii lrrtm11 leucine rich repeat transmembrane neuronal 1 66.41(n)
    66.67(a)
      570385  XM_005160082.1  XP_005160139.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta haf6
    hattifattener
    9(a)
    1 → many
    2L(1555130-1608404)


    ENSEMBL Gene Tree for LRRTM1 (if available)
    TreeFam Gene Tree for LRRTM1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for LRRTM1 gene
    GP52  CPN22  LRIG32  LRRTM42  CHAD2  LRRC152  LRIG22  LRRTM32  
    IGFALS2  CHADL2  LRIG12  LRRTM22  LRG12  
    7 SIMAP similar genes for LRRTM1 using alignment to 4 protein entries:     LRRT1_HUMAN (see all proteins):
    LRRTM3    LRRTM4    LRRTM2    SLIT3    LGR5    SLIT2
    LGR4

    LRRTM1 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for LRRTM1
    PGOHUM00000257113


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    1 SNPs for LRRTM1    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 2 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs67338711,2,4
    ----see VAR_0226812 mis40--------

    HapMap Linkage Disequilibrium report for LRRTM1 (80515483 - 80531874 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for LRRTM1:    About this table    
    Variant IDTypeSubtypePubMed ID
    dgv1209e1CNV Complex17122850
    dgv1208e1CNV Complex17122850

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing LRRTM1
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 610867    OMIM disorders: --

    5 diseases for LRRTM1:    About MalaCards
    autism spectrum disorder    neuronitis    schizophrenia    cerebritis
    asthma

    1 disease from the University of Copenhagen DISEASES database for LRRTM1:
    Schizophrenia

    LRRTM1 for disorders           About GeneDecksing

    Genetic Association Database (GAD): LRRTM1
    Human Genome Epidemiology (HuGE) Navigator: LRRTM1 (2 documents)

    Export disorders for LRRTM1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for LRRTM1 gene, integrated from 10 sources (see all 21):
    (articles sorted by number of sources associating them with LRRTM1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. A novel gene family encoding leucine-rich repeat transmembrane proteins differentially expressed in the nervous system. (PubMed id 12676565)1, 2, 3 Lauren J.... Timmusk T.T. (Genomics 2003)
    2. Family-based analysis of genetic variation underlying psychosis-inducing effects of cannabis: sibling analysis and proband follow-up. (PubMed id 21041608)1, 4 van Winkel R. (Arch. Gen. Psychiatry 2011)
    3. LRRTM1 on chromosome 2p12 is a maternally suppressed gene that is associated paternally with handedness and schizophrenia. (PubMed id 17667961)1, 2 Francks C.... Monaco A.P. (Mol. Psychiatry 2007)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    6. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (Genome Res. 2003)
    7. Genome-wide association study of lung function decline in adults with and without asthma. (PubMed id 22424883)4 Imboden M....Probst-Hensch N.M. (J. Allergy Clin. Immunol. 2012)
    8. UGT1A1 is a major locus influencing bilirubin levels in African Americans. (PubMed id 22085899)4 Chen G....Rotimi C.N. (Eur. J. Hum. Genet. 2012)
    9. Bidirectional transcription from human LRRTM2/CTNNA1 and LRRTM1/CTNNA2 gene loci leads to expression of N-terminally truncated CTNNA1 and CTNNA2 isoforms. (PubMed id 21708131)1 Kask M.... Timmusk T. (Biochem. Biophys. Res. Commun. 2011)
    10. Genomewide association study of movement-related adverse antipsychotic effects. (PubMed id 19875103)4 Aberg K....van den Oord E.J. (Biol. Psychiatry 2010)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 347730 HGNC: 19408 AceView: LRRTM1 Ensembl:ENSG00000162951 euGenes: HUgn347730
    ECgene: LRRTM1 H-InvDB: LRRTM1

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for LRRTM1 Pharmacogenomics, SNPs, Pathways
    Protein Spotlighthttp://web.expasy.org/spotlight/back_issues/091

    (Patent information from GeneIP,
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    Patent Information for LRRTM1 gene:
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