LRRK1 Gene
protein-coding GIFtS: 54
GCID: GC15P101459
|
|
leucine-rich repeat kinase 1
| |
Aliases
for LRRK1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Leucine-Rich Repeat Kinase 11 2 | | FLJ231191 | | RIPK61 2 | | Leucine-Rich Repeat Serine/Threonine-Protein Kinase 12 | | Roco11 2 | | EC 2.7.11.13 | | KIAA17901 3 | | |
Export aliases for LRRK1 gene to outside databasesPrevious GC identifers: GC15P099297 GC15P099380 GC15P077581 |
Summaries
for LRRK1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Gene Wiki entry for LRRK1
|
Genomic Views
for LRRK1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000015.9 NC_018926.1 NT_010274.17
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the LRRK1 gene promoter:
AML1a p300 LCR-F1 Tal-1beta MEF-2A Pax-3 HOXA5 aMEF-2 TGIF ITF-2
Other transcription factors
Search SABiosciences Chromatin IP Primers for LRRK1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat LRRK1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 15q26.3 Ensembl cytogenetic band: 15q26.3 HGNC cytogenetic band: 15q26.3LRRK1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 15 GeneLoc Exon Structure GeneLoc location for GC15P101459: view genomic region
(about GC identifiers)
Start:
|
101,459,420 bp from pter |
End:
|
101,610,317 bp from pter |
Size:
|
150,898 bases |
Orientation:
|
plus strand |
|
Proteins
for LRRK1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: LRRK1_HUMAN, Q38SD2 (See
protein sequence)Recommended Name: Leucine-rich repeat serine/threonine-protein kinase 1 Size: 2015 amino acids; 225393 Da
Cofactor: Magnesium or manganese
Subunit: Homodimer
Subcellular location: Cytoplasm
Sequence caution: Sequence=AAY67799.1; Type=Miscellaneous discrepancy; Note=The cDNA contains a duplication of exon 3;Sequence=BAB15547.1; Type=Erroneous initiation; Note=Translation N-terminally extended; Sequence=BAC85472.1;Type=Erroneous initiation; Note=Translation N-terminally extended;
Secondary accessions: Q6NVH5 Q6NYC0 Q6ZNL9 Q6ZNM9 Q96JN5 Q9H5S3Alternative splicing: 2 isoforms: Q38SD2-1 Q38SD2-2 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for LRRK1: NX_Q38SD2
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q38SD2
LRRK1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_078928.3
ENSEMBL proteins: ENSP00000373600 ENSP00000435148 ENSP00000433268 ENSP00000433069 ENSP00000431668 ENSP00000436672 ENSP00000284395
Human Recombinant Protein Products:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table
LRRK1 for ontologies About GeneDecksing
LRRK1 Antibody Products:
Assay Products for LRRK1: |
Protein
Domains /
Families
for LRRK1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
LRRK1 for domains About GeneDecksing
5/9 InterPro domains/families (see all 9):Graphical View of Domain Structure for InterPro Entry Q38SD2ProtoNet protein and cluster: Q38SD2 1 Blocks protein family: IPB013684 Miro-like
UniProtKB/Swiss-Prot: LRRK1_HUMAN, Q38SD2Similarity: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. ROCO subfamilySimilarity: Contains 4 ANK repeatsSimilarity: Contains 13 LRR (leucine-rich) repeatsSimilarity: Contains 1 protein kinase domainSimilarity: Contains 1 Roc domain |
Function
for LRRK1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: LRRK1_HUMAN, Q38SD2Catalytic activity: ATP + a protein = ADP + a phosphoproteinEnzyme regulation: Binding of GTP stimulates kinase activityEnzyme Number (IUBMB): EC 2.7.11.11
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for LRRK1 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for LRRK1 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: LRRK1 (NM_024652) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for LRRK1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat LRRK1 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for LRRK1 |
Gene Ontology (GO): 5/6 molecular function terms (GO ID links to tree view) (see all 6): About this table
LRRK1 for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for LRRK1:
Animal Models:
Mouse knock-out Lrrk1tm1.1Mjff for LRRK1
1 MGI mutant phenotype (inferred from 1 allele ) (MGI details for Lrrk1):
LRRK1 for phenotypes About GeneDecksing
|
Pathways & Interactions
for LRRK1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for LRRK1
STRING Interaction
Network Preview (showing 5 interactants - click image to see 10)
5/14 Interacting proteins for LRRK1 (Q38SD21, 3 ENSP000003736004) via UniProtKB, MINT, STRING, and/or I2D (see all 14)About this table
Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0007264 | small GTPase mediated signal transduction |
IEA | -- |
LRRK1 for ontologies About GeneDecksing
|
Drugs & Compounds
for LRRK1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for LRRK1
5 HMDB Compounds for LRRK1 About this table
Search CenterWatch for drugs/clinical trials and news about LRRK1
|
Transcripts
for LRRK1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for LRRK1 gene: NM_024652.3 Unigene Cluster for LRRK1: Leucine-rich repeat kinase 1 Hs.407918 [show with all ESTs]Unigene Representative Sequence: NM_02465212 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000388948(uc002bwr.3 uc010usb.2 uc010usc.2) ENST00000534045
ENST00000527698 ENST00000532029(uc002bwq.1) ENST00000525284 ENST00000531270
ENST00000525617 ENST00000538064 ENST00000526457(uc002bws.3) ENST00000525395
ENST00000532145 ENST00000284395
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for LRRK1 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for LRRK1 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: LRRK1 (NM_024652) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for LRRK1 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat LRRK1 |
Additional cDNA sequence: AB058693.1 AK026772.1 AK054662.1 AK058028.1 AK094556.1 AK130975.1 AK131075.1 AK225575.1 BC005408.1 BC018934.1 BC020379.1 BC066655.1 BC068080.1 BC110293.1 BC144705.1 BC146769.1 BC171802.1 DQ013130.1 10 DOTS entries: DT.100751216 DT.100751215 DT.99929164 DT.113762 DT.40128487 DT.95370489 DT.99999678 DT.308471 DT.91829562 DT.97779662 24/96 AceView cDNA sequences (see all 96): AK054662 BC066655 AA781948 CD742790 CF529459 BE463770 AA742267 AI126719 AW241403 AK131075 AW502995 AA430539 AW590768 BQ940155 W60132 BE907578 AW502154 NM_024652 BQ187037 BM354115 AI962086 BM469840 AA280028 AK026772
GeneLoc Exon Structure
4 Alternative Splicing Database (ASD) splice patterns (SP) for LRRK1 About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12a | · | 12b | ^ | 13 | ^ | 14 | ^ | 15 | ^ | 16 | ^ | 17 | ^ | 18 | ^ | 19a | · | 19b | · | 19c | ^ | 20 | ^ | 21 | ^ | 22 |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | - | | | | | | | | - | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | - | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | - | | | |
ECgene alternative splicing isoforms for LRRK1
|
Expression
for LRRK1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| LRRK1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GCTGCAGTGA
About this image
See LRRK1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for LRRK1
SOURCE GeneReport for Unigene cluster: Hs.407918
SABiosciences Custom PCR Arrays for LRRK1
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for LRRK1
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat LRRK1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat LRRK1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat LRRK1 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for LRRK1 |
Orthologs
for LRRK1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for LRRK1 gene from 7/18 species (see all 18) About this table
ENSEMBL Gene Tree for LRRK1 (if available)
TreeFam Gene Tree for LRRK1 (if available) |
Paralogs
for LRRK1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for LRRK1 gene
- LRRK22
6 SIMAP similar genes for LRRK1 using alignment to 8 protein entries: LRRK1_HUMAN (see all proteins):NEK9 PRKCH MAP3K11 BRAF MARK4 STK25
LRRK1 for paralogs About GeneDecksing
|
Genomic Variants
for LRRK1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 15 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for LRRK1 (101459420 - 101610317 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 6 variations for LRRK1
6 CNVs: 2201 7087 8807 3982 49638 7086 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing LRRK1 |
|
Disorders
/ Diseases
for LRRK1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
LRRK1 for disorders About GeneDecksing
OMIM gene information: 610986
OMIM disorders: --
1  disease for LRRK1: About MalaCardsparkinson's disease
1 disease from the University of Copenhagen DISEASES database for LRRK1:Parkinson's disease 3 Novoseek disease relationships for LRRK1 gene About this table
Human Genome Epidemiology (HuGE) Navigator: LRRK1 (3 documents)
Export disorders for LRRK1 gene to outside databases
|
Publications
for LRRK1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for LRRK1 gene, integrated from 9 sources (see all 25):
(articles sorted by number of sources associating them with LRRK1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 11347906)1, 2, 3 Nagase T.... Ohara O. (2001)
- LRRK1 protein kinase activity is stimulated upon binding of GTP to its Roc domain. (PubMed id 16243488)1, 2, 9 Korr D.... Weiss B. (2006)
- Biochemical characterization of highly purified leucine-rich repeat kinases 1 and 2 demonstrates formation of homodimers. (PubMed id 22952686)1, 2 Civiero L.... Taymans J.M. (2012)
- Analysis of the DNA sequence and duplication history of human chromosome 15. (PubMed id 16572171)1, 2 Zody M.C....Nusbaum C. (2006)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Roc, a Ras/GTPase domain in complex proteins. (PubMed id 14654223)1, 3 Bosgraaf L. and Van Haastert P.J. (2003)
- Variants in the LRRK1 gene and susceptibility to Parkinson's disease in Norway. (PubMed id 17324517)1, 9 Haugarvoll K....Farrer M.J. (2007)
- Leucine-rich repeat kinase 1: a paralog of LRRK2 and a candidate gene for Parkinson's disease. (PubMed id 17225181)1, 9 Taylor J.P....Farrer M.J. (2007)
- Mutations in LRRK2/dardarin associated with Parkinson disease are more toxic than equivalent mutations in the homologous kinase LRRK1. (PubMed id 17394548)1, 9 Greggio E....Cookson M.R. (2007)
|
External Searches for LRRK1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing LRRK1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing LRRK1 gene
(According to HUGE)
About This Section
| |
Specialized Databases showing LRRK1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for LRRK1 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for LRRK1 gene:
Search GeneIP for patents involving LRRK1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for LRRK1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | Browse OriGene shRNA RFPs | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for LRRK1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for LRRK1 | | | OriGene Protein Over-expression Lysate for LRRK1 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for LRRK1 | | OriGene 3'-UTR Clone for LRRK1 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for LRRK1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for LRRK1 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for LRRK1 | | OriGene Custom Protein Services for LRRK1 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat LRRK1 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing LRRK1 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat LRRK1 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat LRRK1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat LRRK1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat LRRK1 |
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 | | | LRRK1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for LRRK1 |
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