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Aliases for LRRIQ1 Gene

Aliases for LRRIQ1 Gene

  • Leucine-Rich Repeats And IQ Motif Containing 1 2 3
  • KIAA1801 4

External Ids for LRRIQ1 Gene

Previous GeneCards Identifiers for LRRIQ1 Gene

  • GC12P083934
  • GC12P085430
  • GC12P082487

Summaries for LRRIQ1 Gene

GeneCards Summary for LRRIQ1 Gene

LRRIQ1 (Leucine-Rich Repeats And IQ Motif Containing 1) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for LRRIQ1 Gene

Genomics for LRRIQ1 Gene

Regulatory Elements for LRRIQ1 Gene

Genomic Location for LRRIQ1 Gene

85,036,314 bp from pter
85,264,457 bp from pter
228,144 bases
Plus strand

Genomic View for LRRIQ1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for LRRIQ1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for LRRIQ1 Gene

Proteins for LRRIQ1 Gene

  • Protein details for LRRIQ1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Leucine-rich repeat and IQ domain-containing protein 1
    Protein Accession:
    Secondary Accessions:
    • Q567P4
    • Q9BS17
    • Q9HA36

    Protein attributes for LRRIQ1 Gene

    1722 amino acids
    Molecular mass:
    199300 Da
    Quaternary structure:
    No Data Available
    • Sequence=AAH93088.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential poly-A sequence.; Evidence={ECO:0000305}; Sequence=BAB47430.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305}; Sequence=BAB47430.1; Type=Miscellaneous discrepancy; Note=Probable cloning artifact.; Evidence={ECO:0000305};

    Alternative splice isoforms for LRRIQ1 Gene


neXtProt entry for LRRIQ1 Gene

Proteomics data for LRRIQ1 Gene at MOPED

Post-translational modifications for LRRIQ1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for LRRIQ1 Gene

No data available for DME Specific Peptides for LRRIQ1 Gene

Domains for LRRIQ1 Gene

Protein Domains for LRRIQ1 Gene

Suggested Antigen Peptide Sequences for LRRIQ1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Q96JM4
  • Contains 3 IQ domains.
  • Contains 1 LRRCT domain.
  • Contains 10 LRR (leucine-rich) repeats.
genes like me logo Genes that share domains with LRRIQ1: view

No data available for Gene Families for LRRIQ1 Gene

Function for LRRIQ1 Gene

Gene Ontology (GO) - Molecular Function for LRRIQ1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding --
genes like me logo Genes that share ontologies with LRRIQ1: view

Animal Model Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for LRRIQ1

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for LRRIQ1 Gene

Localization for LRRIQ1 Gene

Subcellular locations from

Jensen Localization Image for LRRIQ1 Gene COMPARTMENTS Subcellular localization image for LRRIQ1 gene
Compartment Confidence
cytosol 2
nucleus 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for LRRIQ1 Gene

Pathways for LRRIQ1 Gene

SuperPathways for LRRIQ1 Gene

No Data Available

Interacting Proteins for LRRIQ1 Gene

Gene Ontology (GO) - Biological Process for LRRIQ1 Gene


No data available for Pathways by source for LRRIQ1 Gene

Transcripts for LRRIQ1 Gene

Unigene Clusters for LRRIQ1 Gene

Leucine-rich repeats and IQ motif containing 1:
Representative Sequences:

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for LRRIQ1

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for LRRIQ1 Gene

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11
SP2: -

Relevant External Links for LRRIQ1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for LRRIQ1 Gene

mRNA expression in normal human tissues for LRRIQ1 Gene

mRNA differential expression in normal tissues according to GTEx for LRRIQ1 Gene

This gene is overexpressed in Testis (14.8).

Protein differential expression in normal tissues for LRRIQ1 Gene

This gene is overexpressed in Plasma (25.9), Liver, secretome (20.0), and Pancreas (6.1).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for LRRIQ1 Gene

SOURCE GeneReport for Unigene cluster for LRRIQ1 Gene Hs.402200

genes like me logo Genes that share expressions with LRRIQ1: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt and Expression partners for LRRIQ1 Gene

Orthologs for LRRIQ1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for LRRIQ1 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia LRRIQ1 35
  • 83.1 (n)
  • 73.41 (a)
  • 73 (a)
(Canis familiaris)
Mammalia LRRIQ1 35
  • 83.88 (n)
  • 73.84 (a)
  • 73 (a)
(Mus musculus)
Mammalia Lrriq1 35
  • 72.76 (n)
  • 59.87 (a)
Lrriq1 16
Lrriq1 36
  • 60 (a)
(Pan troglodytes)
Mammalia LRRIQ1 35
  • 99.52 (n)
  • 99.01 (a)
  • 99 (a)
(Rattus norvegicus)
Mammalia Lrriq1 35
  • 72.6 (n)
  • 56.93 (a)
(Monodelphis domestica)
Mammalia LRRIQ1 36
  • 43 (a)
(Ornithorhynchus anatinus)
Mammalia LRRIQ1 36
  • 45 (a)
(Gallus gallus)
Aves LRRIQ1 35
  • 60.24 (n)
  • 44.25 (a)
  • 40 (a)
(Anolis carolinensis)
Reptilia LRRIQ1 36
  • 40 (a)
(Danio rerio)
Actinopterygii lrriq1 35
  • 50.16 (n)
  • 39.71 (a)
lrriq1 36
  • 31 (a)
Species with no ortholog for LRRIQ1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for LRRIQ1 Gene

Gene Tree for LRRIQ1 (if available)
Gene Tree for LRRIQ1 (if available)

Paralogs for LRRIQ1 Gene

No data available for Paralogs for LRRIQ1 Gene

Variants for LRRIQ1 Gene

Sequence variations from dbSNP and Humsavar for LRRIQ1 Gene

SNP ID Clin Chr 12 pos Sequence Context AA Info Type MAF
rs168613 -- 85,074,606(-) GAAAG(G/T)TAGTA intron-variant
rs168614 -- 85,099,093(-) TCATT(A/G)AATTA intron-variant
rs168615 -- 85,138,012(+) AATAC(A/G)TTAAG intron-variant
rs168616 -- 85,117,878(-) GTTTT(C/T)TTAAA intron-variant
rs189648 -- 85,133,079(+) GTTGT(C/T)AGAAA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for LRRIQ1 Gene

Variant ID Type Subtype PubMed ID
nsv899377 CNV Loss 21882294
nsv510605 CNV Loss 20534489
nsv899387 CNV Loss 21882294
nsv899388 CNV Loss 21882294
nsv899389 CNV Loss 21882294
nsv899390 CNV Loss 21882294
esv2638439 CNV Insertion 19546169
esv271261 CNV Insertion 20981092
esv273028 CNV Insertion 20981092
nsv899391 CNV Loss 21882294
esv271530 CNV Insertion 20981092
nsv826466 CNV Gain 20364138
nsv819416 CNV Gain 19587683
esv270571 CNV Insertion 20981092
nsv899392 CNV Loss 21882294

Relevant External Links for LRRIQ1 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for LRRIQ1 Gene

Disorders for LRRIQ1 Gene

Relevant External Links for LRRIQ1

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator

No disorders were found for LRRIQ1 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships and Genatlas for LRRIQ1 Gene

Publications for LRRIQ1 Gene

  1. Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PMID: 11347906) Nagase T. … Ohara O. (DNA Res. 2001) 2 3 4
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3 48
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4
  5. The finished DNA sequence of human chromosome 12. (PMID: 16541075) Scherer S.E. … Gibbs R.A. (Nature 2006) 4

Products for LRRIQ1 Gene

Sources for LRRIQ1 Gene

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