Aliases for LRRFIP2 Gene
External Ids for LRRFIP2 Gene
Previous GeneCards Identifiers for LRRFIP2 Gene
GeneCards Summary for LRRFIP2 Gene
LRRFIP2 (Leucine Rich Repeat (In FLII) Interacting Protein 2) is a Protein Coding gene. Diseases associated with LRRFIP2 include Lynch Syndrome. GO annotations related to this gene include protein dimerization activity and LRR domain binding. An important paralog of this gene is LRRFIP1.
UniProtKB/Swiss-Prot for LRRFIP2 Gene
May function as activator of the canonical Wnt signaling pathway, in association with DVL3, upstream of CTNNB1/beta-catenin. Positively regulates Toll-like receptor (TLR) signaling in response to agonist probably by competing with the negative FLII regulator for MYD88-binding.