LRRC8A Gene
protein-coding GIFtS: 52
GCID: GC09P131644
|
|
leucine rich repeat containing 8 family, member A(Previous name: leucine rich repeat containing 8 )
(Previous symbol: LRRC8)
| |
Aliases
for LRRC8A gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Leucine Rich Repeat Containing 8 Family, Member A1 2 | | FLJ103371 | | LRRC81 2 3 | | Leucine Rich Repeat Containing 81 | | KIAA14371 3 5 | | Leucine-Rich Repeat-Containing Protein 8A2 | | AGM52 5 | | |
Export aliases for LRRC8A gene to outside databasesPrevious GC identifers: GC09P128728 GC09P130684 GC09P101252 |
Summaries
for LRRC8A gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for LRRC8A:
This gene encodes a protein belonging to the leucine-rich repeat family of proteins, which are involved in diversebiological processes, including cell adhesion, cellular trafficking, and hormone-receptor interactions. This familymember is a putative four-pass transmembrane protein that plays a role in B cell development. Defects in this genecause autosomal dominant non-Bruton type agammaglobulinemia, an immunodeficiency disease resulting from defects in Bcell maturation. Multiple alternatively spliced transcript variants, which encode the same protein, have beenidentified for this gene. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: LRC8A_HUMAN, Q8IWT6Function: Involved in B-cell development. Required for the pro-B cell to pre-B cell transition (By similarity)
Gene Wiki entry for LRRC8A
|
Genomic Views
for LRRC8A gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000009.11 NC_018920.1 NT_008470.19
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the LRRC8A gene promoter:
MAZR COUP AP-4 Pax-4a Arnt
Other transcription factors
Search SABiosciences Chromatin IP Primers for LRRC8A
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat LRRC8A |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 9q34.11 Ensembl cytogenetic band: 9q34.11 HGNC cytogenetic band: 9q34.2LRRC8A Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 9 GeneLoc Exon Structure GeneLoc location for GC09P131644: view genomic region
(about GC identifiers)
Start:
|
131,644,391 bp from pter |
End:
|
131,680,318 bp from pter |
Size:
|
35,928 bases |
Orientation:
|
plus strand |
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Proteins
for LRRC8A gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: LRC8A_HUMAN, Q8IWT6 (See
protein sequence)Recommended Name: Leucine-rich repeat-containing protein 8A Size: 810 amino acids; 94199 Da
Subcellular location: Membrane; Multi-pass membrane protein (Potential)
Sequence caution: Sequence=AAQ88653.1; Type=Erroneous initiation; Sequence=BAA92675.1; Type=Erroneous initiation;Sequence=BAC11161.1; Type=Erroneous initiation;
Secondary accessions: Q6UXM2 Q8NCI0 Q9P2B1Explore the universe of human proteins at neXtProt for LRRC8A: NX_Q8IWT6
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q8IWT6
LRRC8A Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (3 alternative transcripts):
NP_001120716.1 NP_001120717.1 NP_062540.2
ENSEMBL proteins: ENSP00000361682 ENSP00000361680 ENSP00000259324
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0016021 | integral to membrane |
IEA | -- |
LRRC8A for ontologies About GeneDecksing
LRRC8A Antibody Products:
Assay Products for LRRC8A: |
Protein
Domains /
Families
for LRRC8A gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
LRRC8A for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q8IWT6ProtoNet protein and cluster: Q8IWT6 UniProtKB/Swiss-Prot: LRC8A_HUMAN, Q8IWT6Similarity: Contains 17 LRR (leucine-rich) repeats |
Function
for LRRC8A gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: LRC8A_HUMAN, Q8IWT6Function: Involved in B-cell development. Required for the pro-B cell to pre-B cell transition (By similarity)
Clone
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OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for LRRC8A (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
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In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for LRRC8A |
2 GenomeRNAi human phenotypes for LRRC8A:
Animal Models:
Mouse knock-out Lrrc8atm1Lex for LRRC8A
1 MGI phenotypic allele  for Lrrc8a (no phenotypes)
LRRC8A for phenotypes About GeneDecksing
|
Pathways & Interactions
for LRRC8A gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for LRRC8A
STRING Interaction
Network Preview (showing 2 interactants - click image to see more details)
2 Interacting proteins for LRRC8A (ENSP000002593244) via UniProtKB, MINT, STRING, and/or I2DAbout this table
Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0002329 | pre-B cell differentiation |
ISS | -- |
LRRC8A for ontologies About GeneDecksing
|
Drugs & Compounds
for LRRC8A gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for LRRC8A
Search CenterWatch for drugs/clinical trials and news about LRRC8A / LRC8A
|
Transcripts
for LRRC8A gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for LRRC8A gene (3 alternative transcripts): NM_001127244.1 NM_001127245.1 NM_019594.3 Unigene Cluster for LRRC8A: Leucine rich repeat containing 8 family, member A Hs.643600 [show with all ESTs]Unigene Representative Sequence: NM_0011272445 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000372600(uc004bwl.4 uc010myp.3) ENST00000372599 ENST00000483638
ENST00000492784 ENST00000259324(uc010myq.3)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for LRRC8A (see all 6)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for LRRC8A (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 3): LRRC8A (NM_001127245) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for LRRC8A | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat LRRC8A |
Additional cDNA sequence: AB037858.1 AK001199.1 AK024649.1 AK027495.1 AK074723.1 AK123611.1 AK289842.1 AY143166.1 AY358286.1 BC000775.2 BC051322.1 14 DOTS entries: DT.95254460 DT.446625 DT.40268176 DT.102831288 DT.95254467 DT.100037762 DT.95254469 DT.95309620 DT.97781672 DT.100832878 DT.121146554 DT.95240118 DT.99945396 DT.100812588 24/275 AceView cDNA sequences (see all 275): BQ684743 AI870013 BU167871 BX376144 BI027985 AL708412 AW339965 BC000775 AI686221 CR619448 BU735735 CR619692 BC051322 CA446308 AI439206 AI361483 BQ887429 BM008690 AY143166 AA367255 AI359937 AI094530 AA904590 AA631107
GeneLoc Exon Structure
5/6 Alternative Splicing Database (ASD) splice patterns (SP) for LRRC8A (see all 6) About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | · | 6c | · | 6d | · | 6e | ^ | 7 | ^ | 8a | · | 8b |
|---|
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| SP1: | | | - | | | | - | | - | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | - | | - | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | - | | - | | | | | | | | | | | | - | | | | | | |
| SP4: | | | | | | | | | - | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for LRRC8A
|
Expression
for LRRC8A gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| LRRC8A expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TGGGTCTGAA
About this image
See LRRC8A Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for LRRC8A
SOURCE GeneReport for Unigene cluster: Hs.643600
UniProtKB/Swiss-Prot: LRC8A_HUMAN, Q8IWT6Tissue specificity: Expressed in brain, kidney, ovary, lung, liver, heart, and fetal brain and liver. Found at highlevels in bone marrow; lower levels are detected in peripheral blood cells. Expressed on T-cells as well as onB-lineage cells
SABiosciences Custom PCR Arrays for LRRC8A
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for LRRC8A
Browse OriGene validated miRNA SYBR primer pairs
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Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for LRRC8A |
Orthologs
for LRRC8A gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for LRRC8A gene from 3/12 species (see all 12) About this table
ENSEMBL Gene Tree for LRRC8A (if available)
TreeFam Gene Tree for LRRC8A (if available) |
Paralogs
for LRRC8A gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for LRRC8A gene
- LRRC8E2 LRRC282 LRRC8B2 LRRC8C2 LRRC8D2 LRRC692
6 SIMAP similar genes for LRRC8A using alignment to 1 protein entry: LRC8A_HUMAN:LRRC8C DKFZp666L2010 LRRC8B LRRC5 LRRC8D LRRC8E
LRRC8A for paralogs About GeneDecksing
|
Genomic Variants
for LRRC8A gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 9 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for LRRC8A (131644391 - 131680318 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for LRRC8A: --
Human Gene Mutation Database (HGMD): LRRC8A
Locus Specific Mutation Databases (LSDB): LRRC8A
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing LRRC8A |
|
Disorders
/ Diseases
for LRRC8A gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
LRRC8A for disorders About GeneDecksing
OMIM gene information: 608360
OMIM disorders: 613506
UniProtKB/Swiss-Prot: LRC8A_HUMAN, Q8IWT6
Defects in LRRC8A are the cause of agammaglobulinemia type 5 (AGM5) [MIM:613506]. It is a primaryimmunodeficiency characterized by profoundly low or absent serum antibodies and low or absent circulating B-cells dueto an early block of B-cell development. Affected individuals develop severe infections in the first years of life.Note=A chromosomal aberration involving LRRC8 has been found in a patient with congenital agammaglobulinemia.Translocation t(9;20)(q33.2;q12). The translocation truncates the LRRC8 gene, resulting in deletion of the eighth,ninth, and half of the seventh LRR domains
4  diseases for LRRC8A: About MalaCardsagammaglobulinemia bruton-type agammaglobulinemia immunodeficiency agammaglobulinemia 5
1 disease from the University of Copenhagen DISEASES database for LRRC8A:Agammaglobulinemia Export disorders for LRRC8A gene to outside databases
|
Publications
for LRRC8A gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for LRRC8A gene, integrated from 9 sources (see all 18):
(articles sorted by number of sources associating them with LRRC8A) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- A congenital mutation of the novel gene LRRC8 causes agammaglobulinemia in humans. (PubMed id 14660746)1, 2, 9 Sawada A....Hara J. (2003)
- Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
- DNA sequence and analysis of human chromosome 9. (PubMed id 15164053)1, 2 Humphray S.J.... Dunham I. (2004)
- LRRC8 extracellular domain is composed of 17 leucine-rich repeats. (PubMed id 15183935)1, 2 Smits G. and Kajava A.V. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (2003)
- Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10718198)1, 2 Nagase T.... Ohara O. (2000)
- A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
- A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
|
External Searches for LRRC8A gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing LRRC8A gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing LRRC8A gene
(According to HUGE)
About This Section
| |
Specialized Databases showing LRRC8A gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for LRRC8A | Pharmacogenomics, SNPs, Pathways | | LRRC8Abase | http://bioinf.uta.fi/LRRC8Abase/ |
|
| | |
About This Section
| Patent Information for LRRC8A gene:
Search GeneIP for patents involving LRRC8A
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for LRRC8A gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for LRRC8A | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for LRRC8A | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for LRRC8A | | | OriGene Protein Over-expression Lysate for LRRC8A | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for LRRC8A | | OriGene 3'-UTR Clone for LRRC8A | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for LRRC8A | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for LRRC8A | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for LRRC8A | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat LRRC8A | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing LRRC8A | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat LRRC8A | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat LRRC8A | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat LRRC8A | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat LRRC8A |
| |
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| |  |  |  |  | | | | |
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 | | | LRRC8A Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for LRRC8A |
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| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat LRRC8A |
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