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Aliases for LRRC75B Gene

Aliases for LRRC75B Gene

  • Leucine Rich Repeat Containing 75B 2 3 5
  • Leucine-Rich Repeat-Containing Protein FAM211B 3 4
  • Family With Sequence Similarity 211, Member B 2 3
  • C22orf36 3 4
  • FAM211B 3 4
  • Leucine-Rich Repeat-Containing Protein C22orf36 3
  • Chromosome 22 Open Reading Frame 36 2

External Ids for LRRC75B Gene

Previous HGNC Symbols for LRRC75B Gene

  • C22orf36
  • FAM211B

Previous GeneCards Identifiers for LRRC75B Gene

  • GC22M025185

Summaries for LRRC75B Gene

GeneCards Summary for LRRC75B Gene

LRRC75B (Leucine Rich Repeat Containing 75B) is a Protein Coding gene. An important paralog of this gene is LRRC75A.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for LRRC75B Gene

Genomics for LRRC75B Gene

Regulatory Elements for LRRC75B Gene

Enhancers for LRRC75B Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around LRRC75B on UCSC Golden Path with GeneCards custom track

Promoters for LRRC75B Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around LRRC75B on UCSC Golden Path with GeneCards custom track

Genomic Location for LRRC75B Gene

24,585,620 bp from pter
24,593,208 bp from pter
7,589 bases
Minus strand

Genomic View for LRRC75B Gene

Genes around LRRC75B on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
LRRC75B Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for LRRC75B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for LRRC75B Gene

Proteins for LRRC75B Gene

  • Protein details for LRRC75B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Leucine-rich repeat-containing protein 75B
    Protein Accession:
    Secondary Accessions:
    • Q8N0S9
    • Q8N8B1

    Protein attributes for LRRC75B Gene

    315 amino acids
    Molecular mass:
    34740 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for LRRC75B Gene


neXtProt entry for LRRC75B Gene

Proteomics data for LRRC75B Gene at MOPED

Post-translational modifications for LRRC75B Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for LRRC75B Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for LRRC75B Gene

Domains & Families for LRRC75B Gene

Protein Domains for LRRC75B Gene


Suggested Antigen Peptide Sequences for LRRC75B Gene

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the LRRC75 family.
  • Contains 2 LRR (leucine-rich) repeats.
  • Belongs to the LRRC75 family.
  • Contains 2 LRR (leucine-rich) repeats.
genes like me logo Genes that share domains with LRRC75B: view

No data available for Gene Families for LRRC75B Gene

Function for LRRC75B Gene

genes like me logo Genes that share phenotypes with LRRC75B: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for LRRC75B Gene

Localization for LRRC75B Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for LRRC75B Gene

Pathways & Interactions for LRRC75B Gene

SuperPathways for LRRC75B Gene

No Data Available

Interacting Proteins for LRRC75B Gene

Gene Ontology (GO) - Biological Process for LRRC75B Gene


No data available for Pathways by source and SIGNOR curated interactions for LRRC75B Gene

Drugs & Compounds for LRRC75B Gene

No Compound Related Data Available

Transcripts for LRRC75B Gene

Alternative Splicing Database (ASD) splice patterns (SP) for LRRC75B Gene

No ASD Table

Relevant External Links for LRRC75B Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for LRRC75B Gene

mRNA expression in normal human tissues for LRRC75B Gene

Protein differential expression in normal tissues from HIPED for LRRC75B Gene

This gene is overexpressed in Breast (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for LRRC75B Gene

genes like me logo Genes that share expression patterns with LRRC75B: view

Protein tissue co-expression partners for LRRC75B Gene

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for LRRC75B Gene

Orthologs for LRRC75B Gene

This gene was present in the common ancestor of chordates.

Orthologs for LRRC75B Gene

Organism Taxonomy Gene Similarity Type Details
(Canis familiaris)
Mammalia LOC100682757 35
  • 86.32 (n)
  • 85.26 (a)
FAM211B 36
  • 54 (a)
(Mus musculus)
Mammalia Fam211b 35
  • 83.88 (n)
  • 83.01 (a)
Lrrc75b 16
Fam211b 36
  • 81 (a)
(Pan troglodytes)
Mammalia FAM211B 35
  • 99.47 (n)
  • 99.37 (a)
FAM211B 36
  • 99 (a)
(Rattus norvegicus)
Mammalia Fam211b 35
  • 83.44 (n)
  • 83.33 (a)
(Ornithorhynchus anatinus)
Mammalia FAM211B 36
  • 59 (a)
(Gallus gallus)
Aves C22ORF36 35
  • 69.29 (n)
  • 63.57 (a)
FAM211B 36
  • 53 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia fam211b 35
  • 62.84 (n)
  • 58.52 (a)
(Danio rerio)
Actinopterygii LOC100148888 35
  • 62.12 (n)
  • 61.45 (a)
BX005006.2 36
  • 44 (a)
fam211ba 36
  • 46 (a)
Species with no ortholog for LRRC75B:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for LRRC75B Gene

Gene Tree for LRRC75B (if available)
Gene Tree for LRRC75B (if available)

Paralogs for LRRC75B Gene

Paralogs for LRRC75B Gene Pseudogenes for LRRC75B Gene

genes like me logo Genes that share paralogs with LRRC75B: view

Variants for LRRC75B Gene

Sequence variations from dbSNP and Humsavar for LRRC75B Gene

SNP ID Clin Chr 22 pos Sequence Context AA Info Type
VAR_051125 -

Variation tolerance for LRRC75B Gene

Residual Variation Intolerance Score: 98% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 5.03; 68.56% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Relevant External Links for LRRC75B Gene

Disorders for LRRC75B Gene

Relevant External Links for LRRC75B

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for LRRC75B Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for LRRC75B Gene

Publications for LRRC75B Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 67
  2. Large-scale genome-wide association studies in East Asians identify new genetic loci influencing metabolic traits. (PMID: 21909109) Kim Y.J. … Cho Y.S. (Nat. Genet. 2011) 3
  3. Population-based genome-wide association studies reveal six loci influencing plasma levels of liver enzymes. (PMID: 18940312) Yuan X. … Mooser V. (Am. J. Hum. Genet. 2008) 3
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for LRRC75B Gene

Sources for LRRC75B Gene