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Aliases for LRRC69 Gene

Aliases for LRRC69 Gene

  • Leucine Rich Repeat Containing 69 2 3

External Ids for LRRC69 Gene

Previous GeneCards Identifiers for LRRC69 Gene

  • GC08U901021
  • GC08P092186
  • GC08P092114
  • GC08P087326

Summaries for LRRC69 Gene

GeneCards Summary for LRRC69 Gene

LRRC69 (Leucine Rich Repeat Containing 69) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for LRRC69 Gene

Genomics for LRRC69 Gene

Regulatory Elements for LRRC69 Gene

Genomic Location for LRRC69 Gene

91,101,832 bp from pter
91,219,236 bp from pter
117,405 bases
Plus strand

Genomic View for LRRC69 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for LRRC69 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for LRRC69 Gene

Proteins for LRRC69 Gene

  • Protein details for LRRC69 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Leucine-rich repeat-containing protein 69
    Protein Accession:
    Secondary Accessions:

    Protein attributes for LRRC69 Gene

    347 amino acids
    Molecular mass:
    39592 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for LRRC69 Gene


neXtProt entry for LRRC69 Gene

Proteomics data for LRRC69 Gene at MOPED

Post-translational modifications for LRRC69 Gene

  • Ubiquitination at Lys24
  • Modification sites at PhosphoSitePlus

Other Protein References for LRRC69 Gene

No data available for DME Specific Peptides for LRRC69 Gene

Domains for LRRC69 Gene

Protein Domains for LRRC69 Gene


Suggested Antigen Peptide Sequences for LRRC69 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the LRRC69 family.
  • Contains 8 LRR (leucine-rich) repeats.
  • Belongs to the LRRC69 family.
  • Contains 8 LRR (leucine-rich) repeats.
genes like me logo Genes that share domains with LRRC69: view

No data available for Gene Families for LRRC69 Gene

Function for LRRC69 Gene

Gene Ontology (GO) - Molecular Function for LRRC69 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding --
genes like me logo Genes that share ontologies with LRRC69: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for LRRC69 Gene

Localization for LRRC69 Gene

Subcellular locations from

Jensen Localization Image for LRRC69 Gene COMPARTMENTS Subcellular localization image for LRRC69 gene
Compartment Confidence
cytosol 2
mitochondrion 2
nucleus 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for LRRC69 Gene

Pathways for LRRC69 Gene

SuperPathways for LRRC69 Gene

No Data Available

Interacting Proteins for LRRC69 Gene

Gene Ontology (GO) - Biological Process for LRRC69 Gene


No data available for Pathways by source for LRRC69 Gene

Transcripts for LRRC69 Gene

mRNA/cDNA for LRRC69 Gene

(1) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(7) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for LRRC69 Gene

Leucine rich repeat containing 69:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for LRRC69 Gene

No ASD Table

Relevant External Links for LRRC69 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for LRRC69 Gene

mRNA expression in normal human tissues for LRRC69 Gene

Protein differential expression in normal tissues for LRRC69 Gene

This gene is overexpressed in Bone marrow mesenchymal stem cell (69.0).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for LRRC69 Gene

SOURCE GeneReport for Unigene cluster for LRRC69 Gene Hs.733070

genes like me logo Genes that share expressions with LRRC69: view

Expression partners for LRRC69 Gene

* - Elite partner

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for LRRC69 Gene

Orthologs for LRRC69 Gene

This gene was present in the common ancestor of chordates.

Orthologs for LRRC69 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia LRRC69 35
  • 85.21 (n)
  • 77.52 (a)
LRRC69 36
  • 78 (a)
(Canis familiaris)
Mammalia LRRC69 35
  • 85.21 (n)
  • 76.95 (a)
LRRC69 36
  • 70 (a)
(Mus musculus)
Mammalia Lrrc69 35
  • 75.72 (n)
  • 67.05 (a)
Lrrc69 16
Lrrc69 36
  • 67 (a)
(Pan troglodytes)
Mammalia LRRC69 35
  • 99.81 (n)
  • 99.42 (a)
LRRC69 36
  • 99 (a)
(Rattus norvegicus)
Mammalia Lrrc69 35
  • 76.03 (n)
  • 65.62 (a)
(Monodelphis domestica)
Mammalia LRRC69 36
  • 46 (a)
(Ornithorhynchus anatinus)
Mammalia LRRC69 36
  • 55 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia lrrc69 35
  • 57.05 (n)
  • 45.48 (a)
(Danio rerio)
Actinopterygii si:ch73-302o18.2 35
  • 50.78 (n)
  • 37.5 (a)
LRRC69 36
  • 37 (a)
sea squirt
(Ciona savignyi)
Ascidiacea CSA.5771 36
  • 40 (a)
Species with no ortholog for LRRC69:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for LRRC69 Gene

Gene Tree for LRRC69 (if available)
Gene Tree for LRRC69 (if available)

Paralogs for LRRC69 Gene

No data available for Paralogs for LRRC69 Gene

Variants for LRRC69 Gene

Sequence variations from dbSNP and Humsavar for LRRC69 Gene

SNP ID Clin Chr 08 pos Sequence Context AA Info Type MAF
rs3885968 -- 91,115,209(+) CATAC(A/G)CACAC intron-variant
rs3885969 -- 91,115,235(+) AGAAA(C/T)AGTTT intron-variant
rs3923174 -- 91,191,534(+) TAACT(C/T)ATCTG intron-variant
rs4128119 -- 91,144,313(+) TGCTT(C/T)CTATT intron-variant
rs4129720 -- 91,109,477(-) AAAAT(A/C/G/T)TTAAG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for LRRC69 Gene

Variant ID Type Subtype PubMed ID
essv220 CNV CNV 17122850
nsv831390 CNV Gain 17160897
dgv7833n71 CNV Loss 21882294
esv2656822 CNV Deletion 23128226
nsv465736 CNV Loss 19166990
nsv525292 CNV Loss 19592680
essv3326 CNV CNV 17122850
esv35058 CNV Loss 17911159
esv6601 OTHER Inversion 19470904
esv2523005 CNV Deletion 19546169
esv2195824 CNV Deletion 18987734
esv2737291 CNV Deletion 23290073
esv995698 CNV Deletion 20482838
nsv6301 CNV Insertion 18451855
esv272980 CNV Insertion 20981092
nsv398405 CNV Insertion 16902084
esv1005988 CNV Insertion 20482838
esv2670300 CNV Deletion 23128226
nsv524992 CNV Loss 19592680

Relevant External Links for LRRC69 Gene

HapMap Linkage Disequilibrium report
Human Gene Mutation Database (HGMD)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for LRRC69 Gene

Disorders for LRRC69 Gene

Relevant External Links for LRRC69

Genetic Association Database (GAD)

No disorders were found for LRRC69 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships and Genatlas for LRRC69 Gene

Publications for LRRC69 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. A data set of human endogenous protein ubiquitination sites. (PMID: 20972266) Shi Y. … Qin J. (Mol. Cell Proteomics 2011) 3
  3. DNA sequence and analysis of human chromosome 8. (PMID: 16421571) Nusbaum C. … Lander E.S. (Nature 2006) 4
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for LRRC69 Gene

Sources for LRRC69 Gene

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