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LRRC59 Gene

protein-coding   GIFtS: 50
GCID: GC17M048458

Leucine Rich Repeat Containing 59

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Leucine Rich Repeat Containing 591 2
p342 3 5
Ribosome-Binding Protein P342 3
Leucine-Rich Repeat-Containing Protein 592

External Ids:    HGNC: 288171   Entrez Gene: 553792   Ensembl: ENSG000001088297   OMIM: 6148545   UniProtKB: Q96AG43   

Export aliases for LRRC59 gene to outside databases

Previous GC identifers: GC17M045814 GC17M043826


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for LRRC59 Gene:
LRRC59 (leucine rich repeat containing 59) is a protein-coding gene.

UniProtKB/Swiss-Prot: LRC59_HUMAN, Q96AG4
Function: Required for nuclear import of FGF1, but not that of FGF2. Might regulate nuclear import of exogenous
FGF1 by facilitating interaction with the nuclear import machinery and by transporting cytosolic FGF1 to, and
possibly through, the nuclear pores




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000017.10  NC_018928.2  NT_010783.16  
Regulatory elements:
   Regulatory transcription factor binding sites in the LRRC59 gene promoter:
         ER-alpha   ATF-2   IRF-1   HNF-4alpha2   LCR-F1   Gfi-1   YY1   Evi-1   HNF-4alpha1   CRE-BP1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidLRRC59 promoter sequence
   Search Chromatin IP Primers for LRRC59

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat LRRC59


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17q21.33   Ensembl cytogenetic band:  17q21.33   HGNC cytogenetic band: 17q21.33

LRRC59 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
LRRC59 gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17M048458:  view genomic region     (about GC identifiers)

Start:
48,452,420 bp from pter      End:
48,474,914 bp from pter
Size:
22,495 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: LRC59_HUMAN, Q96AG4 (See protein sequence)
Recommended Name: Leucine-rich repeat-containing protein 59  
Size: 307 amino acids; 34930 Da
Subunit: Can form homodimers. Interacts with SGOL1. Interacts with FGF1
Sequence caution: Sequence=AAF69611.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Sequence=BAG38180.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Secondary accessions: B2RE83 D3DTX8 Q9P189

Explore the universe of human proteins at neXtProt for LRRC59: NX_Q96AG4

Explore proteomics data for LRRC59 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys40, Lys66, Lys73, Lys111, Lys116
  • Modification sites at PhosphoSitePlus

  • See LRRC59 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_060979.2  
    ENSEMBL proteins: 
     ENSP00000459616   ENSP00000225972   ENSP00000459305  

    LRRC59 Human Recombinant Protein Products:

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR001611 Leu-rich_rpt

    Graphical View of Domain Structure for InterPro Entry Q96AG4

    ProtoNet protein and cluster: Q96AG4

    1 Blocks protein domain: IPB001611 Leucine-rich repeat signature

    UniProtKB/Swiss-Prot: LRC59_HUMAN, Q96AG4
    Similarity: Contains 5 LRR (leucine-rich) repeats


    Find genes that share domains with LRRC59           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: LRC59_HUMAN, Q96AG4
    Function: Required for nuclear import of FGF1, but not that of FGF2. Might regulate nuclear import of exogenous
    FGF1 by facilitating interaction with the nuclear import machinery and by transporting cytosolic FGF1 to, and
    possibly through, the nuclear pores

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
    GO:0044822poly(A) RNA binding IDA--
         
    Find genes that share ontologies with LRRC59           About GenesLikeMe


    Phenotypes:
         2 GenomeRNAi human phenotypes for LRRC59:
     Decreased viability  Increased cell number in S and 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for LRRC59
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       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for LRRC59

    miRNA
    Products:
        
    miRTarBase miRNAs that target LRRC59:
    hsa-mir-31-5p (MIRT049898), hsa-mir-155-5p (MIRT020860), hsa-mir-106b-5p (MIRT044334), hsa-mir-7-5p (MIRT025787), hsa-mir-10b-5p (MIRT047442), hsa-mir-331-3p (MIRT043353)

    Block miRNA regulation of human, mouse, rat LRRC59 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate LRRC59 (see all 40):
    hsa-miR-1321 hsa-miR-411 hsa-miR-650 hsa-miR-548l hsa-miR-155 hsa-miR-155* hsa-miR-761 hsa-miR-3612
    SwitchGear 3'UTR luciferase reporter plasmidLRRC59 3' UTR sequence
    Inhib. RNA
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat LRRC59

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for LRRC59


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    LRC59_HUMAN, Q96AG4: Microsome membrane; Single-pass type II membrane protein (By similarity). Endoplasmic
    reticulum membrane; Single-pass type II membrane protein. Nucleus envelope. Note=Localization in the nuclear
    envelope depends upon the nuclear import machinery, including KPNB1
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    endoplasmic reticulum5
    nucleus5
    mitochondrion4
    cytosol2
    peroxisome2

    Gene Ontology (GO): 5 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005635nuclear envelope IEA--
    GO:0005783endoplasmic reticulum IDA--
    GO:0005789endoplasmic reticulum membrane IEA--
    GO:0016021integral component of membrane IEA--
    GO:0042645mitochondrial nucleoid IDA18063578

    Find genes that share ontologies with LRRC59           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for LRRC59
    Interactions:

        Search GeneGlobe Interaction Network for LRRC59

    STRING Interaction Network Preview (showing 5 interactants - click image to see 14)

    Selected Interacting proteins for LRRC59 (Q96AG42, 3 ENSP000002259724) via UniProtKB, MINT, STRING, and/or I2D (see all 112)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    TNFRSF1AP194382, 3, ENSP000001627494MINT-49346 I2D: score=2 STRING: ENSP00000162749
    USP20Q9Y2K63, ENSP000003138114I2D: score=2 STRING: ENSP00000313811
    ESR2Q927313, ENSP000003439254I2D: score=1 STRING: ENSP00000343925
    SGOL1Q5FBB73, ENSP000002637534I2D: score=1 STRING: ENSP00000263753
    MTNR1AP480393, ENSP000003028114I2D: score=2 STRING: ENSP00000302811
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for LRRC59 (LRC59)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for LRRC59 gene: 
    NM_018509.3  

    Unigene Cluster for LRRC59:

    Leucine rich repeat containing 59
    Hs.370927  [show with all ESTs]
    Unigene Representative Sequence: NM_018509
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000503118 ENST00000225972(uc002iqt.3) ENST00000576448
    miRNA
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    Block miRNA regulation of human, mouse, rat LRRC59 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate LRRC59 (see all 40):
    hsa-miR-1321 hsa-miR-411 hsa-miR-650 hsa-miR-548l hsa-miR-155 hsa-miR-155* hsa-miR-761 hsa-miR-3612
    SwitchGear 3'UTR luciferase reporter plasmidLRRC59 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat LRRC59
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    GenScript: all cDNA clones in your preferred vector: LRRC59 (NM_018509)
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat LRRC59
    Primer
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    OriGene qPCR primer pairs and template standards for LRRC59
    OriGene qSTAR qPCR primer pairs in human, mouse for LRRC59
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat LRRC59
      QuantiTect SYBR Green Assays in human, mouse, rat LRRC59
      QuantiFast Probe-based Assays in human, mouse, rat LRRC59

    Additional mRNA sequence: 

    AF119857.1 AK025328.1 AK130572.1 AK316593.1 BC017168.1 BC052279.1 

    21 DOTS entries:

    DT.452042  DT.86837118  DT.97857340  DT.99943210  DT.95217223  DT.100824073  DT.120945873  DT.91777536 
    DT.100824063  DT.95171848  DT.97862540  DT.100768842  DT.100824069  DT.102831855  DT.120945779  DT.95152965 
    DT.95171852  DT.95171860  DT.95328650  DT.97862543  DT.120945879 

    Selected AceView cDNA sequences (see all 661):

    BM747829 CB117344 BQ773244 AL557155 BM764303 CA425662 BQ005587 BM455000 
    BM453692 BG028794 BM708409 BE396356 BU507399 BQ063475 BM834455 BC033695 
    BM927488 AA371478 BE295456 BG116791 BU157313 BM745392 BM128116 BQ689649 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    LRRC59 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    LRRC59 Expression
    About this image


    LRRC59 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 11) fully expand
     
     Brain (Nervous System)    fully expand to see all 4 entries
             Cerebral Cortex
     
     Bone (Muscoskeletal System)
             Bone Marrow
     
     Inner Cell Mass (Early Embryonic Tissues)
             Inner Cell Mass Cells Inner Cell Mass
     
     Trophoblast (Extraembryonic Tissues)
             Trophoblast Cells Trophoblast
     
     Testis (Reproductive System)
             Leydig Cells Testis Interstitium
    LRRC59 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    LRRC59 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.370927

    UniProtKB/Swiss-Prot: LRC59_HUMAN, Q96AG4
    Tissue specificity: Widely expressed

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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for LRRC59 gene from Selected species (see all 15)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Lrrc591 , 5 leucine rich repeat containing 591, 5 89.58(n)1
    95.44(a)1
      11 (58.90 cM)5
    982381  NM_133807.11  NP_598568.11 
     946297675 
    chicken
    (Gallus gallus)
    Aves LRRC591 leucine rich repeat containing 59 70.93(n)
    71.8(a)
      422103  NM_001012570.1  NP_001012588.1 
    lizard
    (Anolis carolinensis)
    Reptilia LRRC596
    leucine rich repeat containing 59
    73(a)
    1 ↔ 1
    2(116227193-116240310)
    African clawed frog
    (Xenopus laevis)
    Amphibia BQ884379.12   -- 84.29(n)    BQ884379.1 
    zebrafish
    (Danio rerio)
    Actinopterygii lrrc591 leucine rich repeat containing 59 61.47(n)
    57.63(a)
      405868  NM_212932.1  NP_998097.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG34086
    --
    28(a)
    1 ↔ 1
    3L(9499918-9502683)
    worm
    (Caenorhabditis elegans)
    Secernentea F56A8.31 F56A8.3 48.38(n)
    39.38(a)
      176740  NM_067329.6  NP_499730.1 


    ENSEMBL Gene Tree for LRRC59 (if available)
    TreeFam Gene Tree for LRRC59 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for LRRC59 gene

    Find genes that share paralogs with LRRC59           About GenesLikeMe


    3 Pseudogenes.org Pseudogenes for LRRC59
    PGOHUM00000248942 PGOHUM00000235756 PGOHUM00000243655


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for LRRC59 (see all 392)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 17 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1859284031,2
    --48459418(+) TCCACC/TTCCTT 1 -- ut310--------
    rs1394686801,2
    --48459437(+) GCAATC/TAGGGA 1 -- ut310--------
    rs1452651351,2
    C--48459459(+) AAATT-/GAGGCA 1 -- ut310--------
    rs285221221,2
    C,F--48459522(+) CCACAG/AGAGCT 1 -- ut31 ese33Minor allele frequency- A:0.20WA 122
    rs2015119261,2
    C--48459531(-) GTCACA/GGGCAG 1 -- ut310--------
    rs72108661,2
    C,F,H--48459713(+) GTTTTG/CCCTCA 1 -- ut31 ese37Minor allele frequency- C:0.12NS EA WA 536
    rs1169227361,2
    C,F--48459773(+) TGCAAG/ATGTTA 1 -- ut311Minor allele frequency- A:0.02NA 120
    rs1496575521,2
    --48459816(+) TAGCCA/CGAGAT 1 -- ut310--------
    rs1152947771,2
    C,F--48459988(+) CATACA/GAAAGT 1 -- ut311Minor allele frequency- G:0.02WA 118
    rs1902456541,2
    C--48460120(+) TGCAGC/GTAACT 1 -- ut310--------

    HapMap Linkage Disequilibrium report for LRRC59 (48452420 - 48474914 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for LRRC59:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv833476CNV Loss17160897
    nsv2080CNV Loss18451855
    nsv833475CNV Loss17160897

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing LRRC59
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 614854    OMIM disorders: --


    Find genes that share disorders with LRRC59           About GenesLikeMe


    Export disorders for LRRC59 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for LRRC59 gene, integrated from 10 sources (see all 39):
    (articles sorted by number of sources associating them with LRRC59)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Nuclear import of exogenous FGF1 requires the ER-protein LRRC59 and the importins Kpnalpha1 and Kpnbeta1. (PubMed id 22321063)1, 2 Zhen Y.... Wiedlocha A. (Traffic 2012)
    2. Shugoshin collaborates with protein phosphatase 2A to protect cohesin. (PubMed id 16541025)1, 2 Kitajima T.S.... Watanabe Y. (Nature 2006)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    5. Interlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MS. (PubMed id 23455922)1 Varjosalo M....Superti-Furga G. (Nat. Methods 2013)
    6. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (Cell 2012)
    7. A promiscuous biotin ligase fusion protein identifies proximal and interacting proteins in mammalian cells. (PubMed id 22412018)1 Roux K.J.... Burke B. (J. Cell Biol. 2012)
    8. Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (amp 2012)
    9. Proteomic analysis of I+4I^1 integrin adhesion complexes reveals I+-subunit-dependent protein recruitment. (PubMed id 22623428)1 Byron A....Humphries M.J. (Proteomics 2012)
    10. SGTA recognizes a noncanonical ubiquitin-like domain in the Bag6-Ubl4A-Trc35 complex to promote endoplasmic reticulum-associated degradation. (PubMed id 23246001)1 Xu Y....Ye Y. (Cell Rep 2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 55379 HGNC: 28817 AceView: PRO1855 Ensembl:ENSG00000108829 euGenes: HUgn55379
    ECgene: LRRC59 H-InvDB: LRRC59

    (According to HUGE)
    About This Section

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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for LRRC59 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for LRRC59 gene:
    Search GeneIP for patents involving LRRC59

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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