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Aliases for LRRC57 Gene

Aliases for LRRC57 Gene

  • Leucine Rich Repeat Containing 57 2 3

External Ids for LRRC57 Gene

Summaries for LRRC57 Gene

GeneCards Summary for LRRC57 Gene

LRRC57 (Leucine Rich Repeat Containing 57) is a Protein Coding gene. An important paralog of this gene is LRRC30.

Gene Wiki entry for LRRC57 Gene

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for LRRC57 Gene

Genomics for LRRC57 Gene

Genomic Location for LRRC57 Gene

Start:
42,537,820 bp from pter
End:
42,548,804 bp from pter
Size:
10,985 bases
Orientation:
Minus strand

Genomic View for LRRC57 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for LRRC57 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for LRRC57 Gene

Regulatory Elements for LRRC57 Gene

Proteins for LRRC57 Gene

  • Protein details for LRRC57 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8N9N7-LRC57_HUMAN
    Recommended name:
    Leucine-rich repeat-containing protein 57
    Protein Accession:
    Q8N9N7
    Secondary Accessions:
    • Q7Z2Z6
    • Q8N1T6

    Protein attributes for LRRC57 Gene

    Size:
    239 amino acids
    Molecular mass:
    26754 Da
    Quaternary structure:
    No Data Available

neXtProt entry for LRRC57 Gene

Proteomics data for LRRC57 Gene at MOPED

Post-translational modifications for LRRC57 Gene

  • Modification sites at PhosphoSitePlus
  • Ubiquitination at Lys35 and Lys140

Other Protein References for LRRC57 Gene

No data available for DME Specific Peptides for LRRC57 Gene

Domains for LRRC57 Gene

Protein Domains for LRRC57 Gene

Suggested Antigen Peptide Sequences for LRRC57 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q8N9N7

UniProtKB/Swiss-Prot:

LRC57_HUMAN
Similarity:
  • Contains 8 LRR (leucine-rich) repeats.:
    • Q8N9N7
genes like me logo Genes that share domains with LRRC57: view

No data available for Gene Families for LRRC57 Gene

Function for LRRC57 Gene

Gene Ontology (GO) - Molecular Function for LRRC57 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding --
genes like me logo Genes that share ontologies with LRRC57: view

miRNA for LRRC57 Gene

miRTarBase miRNAs that target LRRC57

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for LRRC57 Gene

Localization for LRRC57 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for LRRC57 Gene COMPARTMENTS Subcellular localization image for LRRC57 gene
Compartment Confidence
cytosol 2
nucleus 2
extracellular 1
golgi apparatus 1
mitochondrion 1

Gene Ontology (GO) - Cellular Components for LRRC57 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0070062 extracellular exosome IDA 19056867
genes like me logo Genes that share ontologies with LRRC57: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for LRRC57 Gene

Pathways for LRRC57 Gene

SuperPathways for LRRC57 Gene

No Data Available

Interacting Proteins for LRRC57 Gene

Gene Ontology (GO) - Biological Process for LRRC57 Gene

None

No data available for Pathways by source for LRRC57 Gene

Transcripts for LRRC57 Gene

Unigene Clusters for LRRC57 Gene

Leucine rich repeat containing 57:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for LRRC57 Gene

ExUns: 1a · 1b · 1c · 1d · 1e ^ 2 ^ 3a · 3b · 3c ^ 4a · 4b · 4c ^ 5a · 5b ^ 6 ^ 7
SP1: - - -
SP2: -
SP3: -
SP4: - -
SP5:
SP6:

Relevant External Links for LRRC57 Gene

GeneLoc Exon Structure for
LRRC57
ECgene alternative splicing isoforms for
LRRC57

Expression for LRRC57 Gene

mRNA expression in normal human tissues for LRRC57 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for LRRC57 Gene

SOURCE GeneReport for Unigene cluster for LRRC57 Gene Hs.234681

genes like me logo Genes that share expressions with LRRC57: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for LRRC57 Gene

Orthologs for LRRC57 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for LRRC57 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia LRRC57 35
  • 99.72 (n)
  • 100 (a)
LRRC57 36
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia LRRC57 35
  • 89.96 (n)
  • 94.14 (a)
LRRC57 36
  • 93 (a)
OneToOne
dog
(Canis familiaris)
Mammalia LRRC57 35
  • 91.77 (n)
  • 94.98 (a)
LRRC57 36
  • 95 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Lrrc57 35
  • 88.98 (n)
  • 95.4 (a)
Lrrc57 16
Lrrc57 36
  • 95 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia LRRC57 36
  • 85 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia LRRC57 36
  • 82 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Lrrc57 35
  • 89.26 (n)
  • 95.4 (a)
chicken
(Gallus gallus)
Aves LRRC57 35
  • 74.93 (n)
  • 85.71 (a)
LRRC57 36
  • 86 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia LRRC57 36
  • 79 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia lrrc57 35
  • 69.47 (n)
  • 76.47 (a)
zebrafish
(Danio rerio)
Actinopterygii lrrc57 35
  • 67.23 (n)
  • 70.17 (a)
lrrc57 36
  • 70 (a)
OneToOne
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP001491 35
  • 51.4 (n)
  • 46.22 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG3040 35
  • 55.27 (n)
  • 50.21 (a)
CG3040 36
  • 50 (a)
OneToOne
worm
(Caenorhabditis elegans)
Secernentea ZK546.2 35
  • 48.01 (n)
  • 43.59 (a)
ZK546.2 36
  • 21 (a)
OneToOne
thale cress
(Arabidopsis thaliana)
eudicotyledons AT2G30105 35
  • 42.2 (n)
  • 33.03 (a)
rice
(Oryza sativa)
Liliopsida Os10g0456200 35
  • 41.32 (n)
  • 29.95 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 10 (a)
ManyToMany
Species with no ortholog for LRRC57:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for LRRC57 Gene

ENSEMBL:
Gene Tree for LRRC57 (if available)
TreeFam:
Gene Tree for LRRC57 (if available)

Paralogs for LRRC57 Gene

Selected SIMAP similar genes for LRRC57 Gene using alignment to 2 proteins:

Pseudogenes.org Pseudogenes for LRRC57 Gene

genes like me logo Genes that share paralogs with LRRC57: view

Variants for LRRC57 Gene

Sequence variations from dbSNP and Humsavar for LRRC57 Gene

SNP ID Clin Chr 15 pos Sequence Context AA Info Type MAF
rs768118 -- 42,546,282(+) aacaa(A/G)ctttt intron-variant
rs1060293 -- 42,545,300(+) AAGCA(A/T)AAGCA intron-variant
rs1138154 -- 42,543,003(-) atccc(A/G)gctac utr-variant-3-prime
rs2412735 -- 42,546,056(+) CCCTC(A/G)AGCTC intron-variant
rs4430710 -- 42,546,158(+) CCATC(A/G)CTTAT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for LRRC57 Gene

Variant ID Type Subtype PubMed ID
nsv528725 CNV Gain 19592680

Relevant External Links for LRRC57 Gene

HapMap Linkage Disequilibrium report
LRRC57

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for LRRC57 Gene

Disorders for LRRC57 Gene

No disorders were found for LRRC57 Gene.

No data available for UniProtKB/Swiss-Prot for LRRC57 Gene

Publications for LRRC57 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. (PMID: 15146197) Brandenberger R. … Stanton L.W. (Nat. Biotechnol. 2004) 3
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  5. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3

Products for LRRC57 Gene

Sources for LRRC57 Gene

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