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Aliases for LRRC20 Gene

Aliases for LRRC20 Gene

  • Leucine Rich Repeat Containing 20 2 3

External Ids for LRRC20 Gene

Previous GeneCards Identifiers for LRRC20 Gene

  • GC10M071404
  • GC10M071728
  • GC10M072058
  • GC10M066052

Summaries for LRRC20 Gene

GeneCards Summary for LRRC20 Gene

LRRC20 (Leucine Rich Repeat Containing 20) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for LRRC20 Gene

Genomics for LRRC20 Gene

Regulatory Elements for LRRC20 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for LRRC20 Gene

70,298,970 bp from pter
70,382,650 bp from pter
83,681 bases
Minus strand

Genomic View for LRRC20 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for LRRC20 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for LRRC20 Gene

Proteins for LRRC20 Gene

  • Protein details for LRRC20 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Leucine-rich repeat-containing protein 20
    Protein Accession:
    Secondary Accessions:
    • Q5T6D4
    • Q5T6D6
    • Q9NVA6
    • Q9NVG3

    Protein attributes for LRRC20 Gene

    184 amino acids
    Molecular mass:
    20509 Da
    Quaternary structure:
    No Data Available
    • Sequence=BAA91849.1; Type=Erroneous termination; Positions=185; Note=Translated as stop.; Evidence={ECO:0000305};

    Alternative splice isoforms for LRRC20 Gene


neXtProt entry for LRRC20 Gene

Proteomics data for LRRC20 Gene at MOPED

Post-translational modifications for LRRC20 Gene

  • Ubiquitination at Lys43
  • Modification sites at PhosphoSitePlus

Antibody Products

No data available for DME Specific Peptides for LRRC20 Gene

Domains for LRRC20 Gene

Protein Domains for LRRC20 Gene


Suggested Antigen Peptide Sequences for LRRC20 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Contains 5 LRR (leucine-rich) repeats.
  • Contains 5 LRR (leucine-rich) repeats.
genes like me logo Genes that share domains with LRRC20: view

No data available for Gene Families for LRRC20 Gene

Function for LRRC20 Gene

Gene Ontology (GO) - Molecular Function for LRRC20 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with LRRC20: view

Animal Model Products

miRNA for LRRC20 Gene

miRTarBase miRNAs that target LRRC20

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for LRRC20

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for LRRC20 Gene

Localization for LRRC20 Gene

Subcellular locations from

Jensen Localization Image for LRRC20 Gene COMPARTMENTS Subcellular localization image for LRRC20 gene
Compartment Confidence
cytosol 2
nucleus 2
peroxisome 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for LRRC20 Gene

Pathways for LRRC20 Gene

SuperPathways for LRRC20 Gene

No Data Available

Interacting Proteins for LRRC20 Gene

STRING Interaction Network Preview (showing 2 interactants - click image to see details)
Selected Interacting proteins: ENSP00000348043 Q8TCA0-LRC20_HUMAN for LRRC20 Gene via STRING UniProtKB

Gene Ontology (GO) - Biological Process for LRRC20 Gene


No data available for Pathways by source for LRRC20 Gene

Transcripts for LRRC20 Gene

Unigene Clusters for LRRC20 Gene

Leucine rich repeat containing 20:
Representative Sequences:

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for LRRC20

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for LRRC20 Gene

ExUns: 1a · 1b · 1c · 1d ^ 2a · 2b ^ 3a · 3b · 3c ^ 4 ^ 5 ^ 6 ^ 7a · 7b · 7c · 7d · 7e · 7f
SP1: - - - - - -
SP2: - - - - -
SP3: - - -
SP4: - - - - - - -
SP5: - - - - - - -
SP6: - - - - - - -
SP7: - - - - - - - -
SP8: - - - - - - - -
SP10: -

Relevant External Links for LRRC20 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for LRRC20 Gene

mRNA expression in normal human tissues for LRRC20 Gene

mRNA differential expression in normal tissues according to GTEx for LRRC20 Gene

This gene is overexpressed in Muscle - Skeletal (11.6).

Protein differential expression in normal tissues for LRRC20 Gene

This gene is overexpressed in Tonsil (27.4).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for LRRC20 Gene

SOURCE GeneReport for Unigene cluster for LRRC20 Gene Hs.7778

genes like me logo Genes that share expressions with LRRC20: view

Expression partners for LRRC20 Gene

* - Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for LRRC20 Gene

Orthologs for LRRC20 Gene

This gene was present in the common ancestor of animals.

Orthologs for LRRC20 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia LRRC20 35
  • 88.95 (n)
  • 91.3 (a)
LRRC20 36
  • 91 (a)
(Canis familiaris)
Mammalia LRRC20 35
  • 90.58 (n)
  • 93.48 (a)
LRRC20 36
  • 93 (a)
(Mus musculus)
Mammalia Lrrc20 35
  • 84.6 (n)
  • 89.67 (a)
Lrrc20 16
Lrrc20 36
  • 89 (a)
(Pan troglodytes)
Mammalia LRRC20 35
  • 99.82 (n)
  • 100 (a)
LRRC20 36
  • 100 (a)
(Rattus norvegicus)
Mammalia Lrrc20 35
  • 86.41 (n)
  • 90.22 (a)
(Monodelphis domestica)
Mammalia LRRC20 36
  • 76 (a)
(Ornithorhynchus anatinus)
Mammalia LRRC20 36
  • 84 (a)
(Gallus gallus)
Aves LRRC20 35
  • 70.97 (n)
  • 64.61 (a)
(Anolis carolinensis)
Reptilia LRRC20 36
  • 72 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia lrrc20 35
  • 58.33 (n)
  • 55.95 (a)
(Danio rerio)
Actinopterygii lrrc20 35
  • 61.29 (n)
  • 49.68 (a)
lrrc20 36
  • 46 (a)
fruit fly
(Drosophila melanogaster)
Insecta Sclp 36
  • 15 (a)
(Caenorhabditis elegans)
Secernentea K08E7.8 36
  • 25 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 28 (a)
Species with no ortholog for LRRC20:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for LRRC20 Gene

Gene Tree for LRRC20 (if available)
Gene Tree for LRRC20 (if available)

Paralogs for LRRC20 Gene

No data available for Paralogs for LRRC20 Gene

Variants for LRRC20 Gene

Sequence variations from dbSNP and Humsavar for LRRC20 Gene

SNP ID Clin Chr 10 pos Sequence Context AA Info Type MAF
rs1626 -- 70,378,283(-) CAGAG(A/G)AAGGA intron-variant, upstream-variant-2KB
rs928562 -- 70,309,277(+) AAAGC(A/C/G)GGCTG intron-variant
rs945054 -- 70,321,641(-) TCCAG(A/G)AGGGG intron-variant
rs1043867 -- 70,299,335(-) CTGTG(A/C/G/T)TCAGC utr-variant-3-prime, nc-transcript-variant
rs1043875 -- 70,299,326(-) GCCTC(C/T)TCCCT utr-variant-3-prime, nc-transcript-variant

Structural Variations from Database of Genomic Variants (DGV) for LRRC20 Gene

Variant ID Type Subtype PubMed ID
esv32737 CNV Gain+Loss 17666407
nsv831908 CNV Gain 17160897
nsv507560 CNV Insertion 20534489
esv1276689 CNV Insertion 17803354
esv1000318 CNV Deletion 20482838

Relevant External Links for LRRC20 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for LRRC20 Gene

Disorders for LRRC20 Gene

Relevant External Links for LRRC20

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator

No disorders were found for LRRC20 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships and Genatlas for LRRC20 Gene

Publications for LRRC20 Gene

  1. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3 48
  2. Trait-stratified genome-wide association study identifies novel and diverse genetic associations with serologic and cytokine phenotypes in systemic lupus erythematosus. (PMID: 20659327) Kariuki S.N. … Niewold T.B. (Arthritis Res. Ther. 2010) 3 48
  3. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PMID: 12975309) Clark H.F. … Gray A.M. (Genome Res. 2003) 3 4
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  5. The DNA sequence and comparative analysis of human chromosome 10. (PMID: 15164054) Deloukas P. … Rogers J. (Nature 2004) 3 4

Products for LRRC20 Gene

Sources for LRRC20 Gene

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