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LRRC10 Gene

protein-coding   GIFtS: 41
GCID: GC12M070002

Leucine Rich Repeat Containing 10
  Search for LRRC10
at
MalaCards
 

Aliases
for LRRC10 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Leucine Rich Repeat Containing 101 2
HRLRRP2 5
LRRC10A2
Leucine-Rich Repeat-Containing Protein 102

External Ids:    HGNC: 202641   Entrez Gene: 3761322   Ensembl: ENSG000001988127   OMIM: 6108465   UniProtKB: Q5BKY13   

Export aliases for LRRC10 gene to outside databases

Previous GC identifers: GC12U900436 GC12M068288 GC12M067051


Summaries
for LRRC10 gene

(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for LRRC10 Gene:
LRRC10 (leucine rich repeat containing 10) is a protein-coding gene. An important paralog of this gene is LRRC2.

UniProtKB/Swiss-Prot: LRC10_HUMAN, Q5BKY1
Function: May play important roles in cardiac development and/or cardiac function (By similarity)




Genomic Views
for LRRC10 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000012.12  NC_018923.2  NT_029419.13  
Regulatory elements:
   Regulatory transcription factor binding sites in the LRRC10 gene promoter:
         AML1a   Olf-1   AREB6   CREB   SREBP-1a   Zic1   deltaCREB   NF-kappaB1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: LRRC10 promoter sequence
   Search Chromatin IP Primers for LRRC10

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat LRRC10


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12q15   Ensembl cytogenetic band:  12q15   HGNC cytogenetic band: 12q15

LRRC10 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
LRRC10 gene location

GeneLoc information about chromosome 12         GeneLoc Exon Structure

GeneLoc location for GC12M070002:  view genomic region     (about GC identifiers)

Start:
 70,002,344 bp from pter      End:
 70,004,942 bp from pter
Size:
 2,599 bases      Orientation:
 minus strand

Proteins
for LRRC10 gene

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: LRC10_HUMAN, Q5BKY1 (See protein sequence)
Recommended Name: Leucine-rich repeat-containing protein 10  
Size: 277 amino acids; 31642 Da
Sequence caution: Sequence=BAC85724.1; Type=Erroneous initiation;
Secondary accessions: Q6ZVY4

Explore the universe of human proteins at neXtProt for LRRC10: NX_Q5BKY1

Explore proteomics data for LRRC10 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

    • See LRRC10 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_963844.2  
    ENSEMBL proteins: 
     ENSP00000355166  

    LRRC10 Human Recombinant Protein Products:

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    Cloud-Clone Corp. Proteins for LRRC10

    LRRC10 Antibody Products:

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    LSBio Antibodies in human, mouse, rat for LRRC10

    LRRC10 Assay Products:

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    Cloud-Clone Corp. ELISAs for LRRC10
    Cloud-Clone Corp. CLIAs for LRRC10

    Domains /
    Families
    for LRRC10 gene

    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus    		 2 InterPro protein domains:
     IPR001611 Leu-rich_rpt
     IPR025875 Leu-rich_rpt_4

    Graphical View of Domain Structure for InterPro Entry Q5BKY1

    ProtoNet protein and cluster: Q5BKY1

    1 Blocks protein domain: IPB001611 Leucine-rich repeat signature

    UniProtKB/Swiss-Prot: LRC10_HUMAN, Q5BKY1
    Similarity: Contains 7 LRR (leucine-rich) repeats


    LRRC10 for domains           About GeneDecksing


    Function
    for LRRC10 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: LRC10_HUMAN, Q5BKY1
    Function: May play important roles in cardiac development and/or cardiac function (By similarity)

         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003779actin binding IEA--
    GO:0005515protein binding ----
    GO:0051393alpha-actinin binding IEA--
         
    LRRC10 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for LRRC10:
     Synthetic lethal with Ras 

         1 MGI mutant phenotype (inferred from 1 allele) (MGI details for Lrrc10):
     normal 

    LRRC10 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Lrrc10tm1Sgt for LRRC10

       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for LRRC10
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    miRNA
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    5 qRT-PCR Assays for microRNAs that regulate LRRC10:
    hsa-miR-214 hsa-miR-1207-3p hsa-miR-518a-5p hsa-miR-761 hsa-let-7f-2*
    SwitchGear 3'UTR luciferase reporter plasmid: LRRC10 3' UTR sequence
    Inhib. RNA
    Products:            		OriGene RNAi products in human, mouse, rat for LRRC10
    Predesigned siRNA for gene silencing in human, mouse, rat LRRC10

    Gene Editing
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    Clone
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    GenScript: all cDNA clones in your preferred vector: LRRC10 (NM_201550)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for LRRC10
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat LRRC10

    Cell Line
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    In Situ Assay
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    Localization
    for LRRC10 gene

    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    LRC10_HUMAN, Q5BKY1: Nucleus (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytoskeleton2
    mitochondrion2
    nucleus2
    cytosol1
    extracellular1
    peroxisome1

    Gene Ontology (GO): 5 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--
    GO:0005739mitochondrion IEA--
    GO:0005856cytoskeleton IEA--
    GO:0030016myofibril ----
    GO:0030017sarcomere IEA--

    LRRC10 for ontologies           About GeneDecksing


    Pathways & Interactions
    for LRRC10 gene

    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for LRRC10
    Interactions:

        Search GeneGlobe Interaction Network for LRRC10

    STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

    2 Interacting proteins for LRRC10 (ENSP000003551664) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CAB39ENSP000002584184STRING: ENSP00000258418
    CAB39LENSP000002616694STRING: ENSP00000261669
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0055013cardiac muscle cell development IEA--

    LRRC10 for ontologies           About GeneDecksing



    Drugs & Compounds
    for LRRC10 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for LRRC10 (LRC10)



    Transcripts
    for LRRC10 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for LRRC10 gene: 
    NM_201550.2  

    Unigene Cluster for LRRC10:

    Leucine rich repeat containing 10
    Hs.448708  [show with all ESTs]
    Unigene Representative Sequence: NM_201550
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000361484(uc001svc.3)
    miRNA
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    5 qRT-PCR Assays for microRNAs that regulate LRRC10:
    hsa-miR-214 hsa-miR-1207-3p hsa-miR-518a-5p hsa-miR-761 hsa-let-7f-2*
    SwitchGear 3'UTR luciferase reporter plasmid: LRRC10 3' UTR sequence
    Inhib. RNA
    Products:             		OriGene RNAi products in human, mouse, rat for LRRC10
    Predesigned siRNA for gene silencing in human, mouse, rat LRRC10
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    OriGene ORF clones in mouse, rat for LRRC10
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    GenScript: all cDNA clones in your preferred vector: LRRC10 (NM_201550)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for LRRC10
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat LRRC10
    Primer
    Products:            		OriGene qSTAR qPCR primer pairs in human, mouse for LRRC10
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat LRRC10
      QuantiTect SYBR Green Assays in human, mouse, rat LRRC10
      QuantiFast Probe-based Assays in human, mouse, rat LRRC10

    Additional mRNA sequence: 

    AK095935.1 AK123908.1 BC090881.1 BC106892.1 BC106893.1 

    1 DOTS entry:

    DT.40303762 

    6 AceView cDNA sequences:

    NM_201550 AK123908 CF552292 AK095935 N70852 W06861 

    GeneLoc Exon Structure


    Expression
    for LRRC10 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    LRRC10 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TTAGTTTAAA
    LRRC10 Expression
    About this image

    LRRC10 Protein expression data from MOPED1, PaxDb2 and MaxQB3:     About this image

    LRRC10 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.448708
        Custom PCR Arrays for LRRC10
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    In Situ
    Assay Products:     
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for LRRC10

    Orthologs
    for LRRC10 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for LRRC10 gene from Selected species (see all 10)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    mouse
    (Mus musculus)    		 Mammalia Lrrc101 , 5 leucine rich repeat containing 101, 5 85.64(n)1
    88.69(a)1    		   10 (65.06 cM)5
    2375601  NM_146242.21  NP_666354.11 
     1170453415 
    chicken
    (Gallus gallus)    		 Aves LRRC101 leucine rich repeat containing 10 76.46(n)
    79.76(a)    		   427865  XM_004937565.1  XP_004937622.1 
    lizard
    (Anolis carolinensis)    		 Reptilia LRRC106
    		 leucine rich repeat containing 10
    		 70(a)
    		 1 ↔ 1
    		 GL343256.1(1657626-1658453)
    tropical clawed frog
    (Xenopus tropicalis)    		 Amphibia lrrc101 leucine rich repeat containing 10 64.96(n)
    69.6(a)    		   100492390  XM_002938506.2  XP_002938552.2 
    zebrafish
    (Danio rerio)    		 Actinopterygii lrrc101 leucine rich repeat containing 10 61.33(n)
    62.5(a)    		   798207  NM_001009559.1  NP_001009559.1 


    ENSEMBL Gene Tree for LRRC10 (if available)
    TreeFam Gene Tree for LRRC10 (if available)

    Paralogs
    for LRRC10 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for LRRC10 gene
    LRRC22  LRCH22  LRRC182  LRSAM12  LRRC302  PIDD2  LRCH32  LRRC572  
    LRRC10B2  LRRC392  LRCH42  LRCH12  
    4 SIMAP similar genes for LRRC10 using alignment to 3 protein entries:     LRC10_HUMAN (see all proteins):
    LRRC10B    LRRC39    LRRC30    LRRIQ4

    LRRC10 for paralogs           About GeneDecksing



    Genomic Variants
    for LRRC10 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for LRRC10 (see all 119)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 12 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs1932074431,2
    		--70001909(+) GCTTCC/TGTCAT 1 -- int10--------
    rs1856455791,2
    		--70002024(+) AAAGGA/GACCTT 1 -- int10--------
    rs171068221,2
    		C,F,H--70002097(+) ATTATG/ACAACA 1 -- int114Minor allele frequency- A:0.04NA NS EA WA 1450
    rs71365031,2
    		H--70002118(+) TCTAGT/GTTAGC 1 -- int14Minor allele frequency- G:0.00NS EA 420
    rs396791,2
    		C,F,O,A,H--70002265(+) AAGATG/AACACT 1 -- int116Minor allele frequency- A:0.23MN NA WA CSA EA 703
    rs1881557031,2
    		--70002308(+) TACATA/GAAGAA 1 -- int10--------
    rs355072911,2
    		C,F--70002311(+) ATAAAG/TAATTG 1 -- int12Minor allele frequency- T:0.50NA 4
    rs2001259541,2
    		C--70002425(+) ATTGTA/CAAAAC 1 -- ut310--------
    rs111777511,2
    		C,F,H--70002488(+) GAGGCA/GGAGAC 1 -- ut3119Minor allele frequency- G:0.19NS EA NA WA 2338
    rs1508591871,2
    		C--70002552(+) GAACAC/TATTTC 1 -- ut310--------

    HapMap Linkage Disequilibrium report for LRRC10 (70002344 - 70004942 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for LRRC10: --
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing LRRC10
    DNA2.0 Custom Variant and Variant Library Synthesis for LRRC10

    Disorders / Diseases
    for LRRC10 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus    		 OMIM gene information: 610846    OMIM disorders: --


    LRRC10 for disorders           About GeneDecksing

    Genetic Association Database (GAD): LRRC10

    Export disorders for LRRC10 gene to outside databases

    Publications
    for LRRC10 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for LRRC10 gene integrated from 10 sources:
    (articles sorted by number of sources associating them with LRRC10)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Many sequence variants affecting diversity of adult human height. (PubMed id 18391951)1, 4 Gudbjartsson D.F....Stefansson K. (Nat. Genet. 2008)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    3. Molecular cloning and expression of HRLRRP, a novel heart-restricted leucine-rich repeat protein. (PubMed id 14751244)1, 3 Nakane T....Chiba S. (Biochem. Biophys. Res. Commun. 2004)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)

    External Searches for LRRC10 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  
      Query String
    		PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    Genome Databases showing LRRC10 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 376132 HGNC: 20264 AceView: LRRC10 Ensembl:ENSG00000198812 euGenes: HUgn376132
    ECgene: LRRC10 H-InvDB: LRRC10

    Other Databases showing LRRC10 gene

    (According to HUGE)
    About This Section

    TryGeneCards Plus    		   --

    Specialized Databases showing LRRC10 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for LRRC10 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for LRRC10 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus    		Patent Information for LRRC10 gene:
    Search GeneIP for patents involving LRRC10

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    Products
    for LRRC10 gene

    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

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     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for LRRC10  
     Browse OriGene qPCR primer pairs and template standards   OriGene Protein Over-expression Lysate for LRRC10  
     OriGene MassSpec something-or-other for LRRC10   OriGene clones in human, mouse for LRRC10  
     OriGene qSTAR qPCR primer pairs in human, mouse for LRRC10   OriGene Purified Protein for LRRC10  
     OriGene ORF clones in mouse, rat for LRRC10   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for LRRC10   OriGene Custom Protein Services for LRRC10  

         		 
     Block miRNA regulation of human, mouse, rat LRRC10 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing LRRC10
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat LRRC10 Predesigned siRNA for gene silencing in human, mouse, rat LRRC10
     QuantiFast Probe-based Assays in human, mouse, rat LRRC10 QuantiTect SYBR Green Assays in human, mouse, rat LRRC10
     Custom PCR Arrays for LRRC10 Search Chromatin IP Primers for LRRC10
     Pre-validated RT2 qPCR Primer Assay in human, mouse, rat LRRC10  Search GeneGlobe Interaction Network for LRRC10
     Regulatory tfbs in LRRC10 promoter
     GenScript Custom Purified and Recombinant Proteins Services for LRRC10 GenScript cDNA clones with any tag delivered in your preferred vector for LRRC10
     GenScript Custom Assay Services for LRRC10 GenScript Custom overexpressing Cell Line Services for LRRC10
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
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     Search Tocris compounds for LRRC10 (LRC10)
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     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     LRRC10 antibodies
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     Antibodies for LRRC10
     See all of Abcam's Antibodies, Kits and Proteins for LRRC10
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     Browse ProSpec Recombinant Proteins
     Proteins for LRRC10
     Antibodies for LRRC10
     ELISAs for LRRC10
     CLIAs for LRRC10



     Browse ESI BIO Cell Lines and PureStem Progenitors for LRRC10
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for LRRC10
     SwitchGear 3'UTR luciferase reporter plasmids for LRRC10
     SwitchGear Promoter luciferase reporter plasmids for LRRC10
     Search ThermoFisher Antibodies for LRRC10
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat LRRC10
     inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for LRRC10
     inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for LRRC10
     LSBio Antibodies in human, mouse, rat for LRRC10
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
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