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Aliases for LRRC10 Gene

Aliases for LRRC10 Gene

  • Leucine Rich Repeat Containing 10 2 3
  • HRLRRP 3 6
  • Leucine-Rich Repeat-Containing Protein 10 3
  • LRRC10A 3

External Ids for LRRC10 Gene

Previous GeneCards Identifiers for LRRC10 Gene

  • GC12U900436
  • GC12M068288
  • GC12M070002
  • GC12M067051

Summaries for LRRC10 Gene

GeneCards Summary for LRRC10 Gene

LRRC10 (Leucine Rich Repeat Containing 10) is a Protein Coding gene. An important paralog of this gene is LRRC30.

UniProtKB/Swiss-Prot for LRRC10 Gene

  • May play important roles in cardiac development and/or cardiac function.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for LRRC10 Gene

Genomics for LRRC10 Gene

Regulatory Elements for LRRC10 Gene

Genomic Location for LRRC10 Gene

69,608,564 bp from pter
69,611,162 bp from pter
2,599 bases
Minus strand

Genomic View for LRRC10 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for LRRC10 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for LRRC10 Gene

Proteins for LRRC10 Gene

  • Protein details for LRRC10 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Leucine-rich repeat-containing protein 10
    Protein Accession:
    Secondary Accessions:
    • Q6ZVY4

    Protein attributes for LRRC10 Gene

    277 amino acids
    Molecular mass:
    31642 Da
    Quaternary structure:
    No Data Available
    • Sequence=BAC85724.1; Type=Erroneous initiation; Evidence={ECO:0000305};

neXtProt entry for LRRC10 Gene

Proteomics data for LRRC10 Gene at MOPED

Post-translational modifications for LRRC10 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for LRRC10 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for LRRC10 Gene

Domains for LRRC10 Gene

Protein Domains for LRRC10 Gene

Suggested Antigen Peptide Sequences for LRRC10 Gene

Graphical View of Domain Structure for InterPro Entry



  • Q5BKY1
  • Contains 7 LRR (leucine-rich) repeats.
genes like me logo Genes that share domains with LRRC10: view

No data available for Gene Families for LRRC10 Gene

Function for LRRC10 Gene

Molecular function for LRRC10 Gene

UniProtKB/Swiss-Prot Function: May play important roles in cardiac development and/or cardiac function.

Gene Ontology (GO) - Molecular Function for LRRC10 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003779 actin binding IEA --
GO:0005515 protein binding --
GO:0051393 alpha-actinin binding IEA --
genes like me logo Genes that share ontologies with LRRC10: view

Phenotypes for LRRC10 Gene

MGI mutant phenotypes for LRRC10:
inferred from 1 alleles
GenomeRNAi human phenotypes for LRRC10:
genes like me logo Genes that share phenotypes with LRRC10: view

Animal Models for LRRC10 Gene

MGI Knock Outs for LRRC10:

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , miRNA , Transcription Factor Targeting and HOMER Transcription for LRRC10 Gene

Localization for LRRC10 Gene

Subcellular locations from UniProtKB/Swiss-Prot for LRRC10 Gene

Subcellular locations from

Jensen Localization Image for LRRC10 Gene COMPARTMENTS Subcellular localization image for LRRC10 gene
Compartment Confidence
cytoskeleton 2
mitochondrion 2
nucleus 2
cytosol 1
extracellular 1
peroxisome 1

Gene Ontology (GO) - Cellular Components for LRRC10 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
GO:0005739 mitochondrion IEA --
GO:0005856 cytoskeleton IEA --
GO:0030016 myofibril --
GO:0030017 sarcomere IEA --
genes like me logo Genes that share ontologies with LRRC10: view

Pathways for LRRC10 Gene

SuperPathways for LRRC10 Gene

No Data Available

Interacting Proteins for LRRC10 Gene

Gene Ontology (GO) - Biological Process for LRRC10 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0055013 cardiac muscle cell development IEA --
genes like me logo Genes that share ontologies with LRRC10: view

No data available for Pathways by source for LRRC10 Gene

Transcripts for LRRC10 Gene

mRNA/cDNA for LRRC10 Gene

(6) Selected AceView cDNA sequences:
(1) REFSEQ mRNAs :
(5) Additional mRNA sequences :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for LRRC10 Gene

Leucine rich repeat containing 10:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for LRRC10

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for LRRC10

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for LRRC10 Gene

No ASD Table

Relevant External Links for LRRC10 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for LRRC10 Gene

mRNA expression in normal human tissues for LRRC10 Gene

mRNA differential expression in normal tissues according to GTEx for LRRC10 Gene

This gene is overexpressed in Heart - Left Ventricle (35.6) and Heart - Atrial Appendage (15.6).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for LRRC10 Gene

SOURCE GeneReport for Unigene cluster for LRRC10 Gene Hs.448708

genes like me logo Genes that share expressions with LRRC10: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for LRRC10 Gene

Orthologs for LRRC10 Gene

This gene was present in the common ancestor of chordates.

Orthologs for LRRC10 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia LRRC10 35
  • 99.52 (n)
  • 99.64 (a)
LRRC10 36
  • 100 (a)
(Bos Taurus)
Mammalia LRRC10 35
  • 91.1 (n)
  • 92.86 (a)
LRRC10 36
  • 92 (a)
(Canis familiaris)
Mammalia LRRC10 35
  • 83.15 (n)
  • 81.04 (a)
LRRC10 36
  • 79 (a)
(Mus musculus)
Mammalia Lrrc10 35
  • 85.64 (n)
  • 88.69 (a)
Lrrc10 16
Lrrc10 36
  • 88 (a)
(Monodelphis domestica)
Mammalia LRRC10 36
  • 80 (a)
(Rattus norvegicus)
Mammalia Lrrc10 35
  • 84.86 (n)
  • 88.64 (a)
(Gallus gallus)
Aves LRRC10 35
  • 76.46 (n)
  • 79.76 (a)
LRRC10 36
  • 74 (a)
(Anolis carolinensis)
Reptilia LRRC10 36
  • 70 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia lrrc10 35
  • 64.96 (n)
  • 69.6 (a)
(Danio rerio)
Actinopterygii lrrc10 35
  • 61.33 (n)
  • 62.5 (a)
lrrc10 36
  • 59 (a)
Species with no ortholog for LRRC10:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for LRRC10 Gene

Gene Tree for LRRC10 (if available)
Gene Tree for LRRC10 (if available)

Paralogs for LRRC10 Gene

Selected SIMAP similar genes for LRRC10 Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with LRRC10: view

Variants for LRRC10 Gene

Sequence variations from dbSNP and Humsavar for LRRC10 Gene

SNP ID Clin Chr 12 pos Sequence Context AA Info Type MAF
rs28204 -- 69,609,715(+) CTTTT(A/G)CTCTT utr-variant-3-prime
rs39679 -- 69,608,485(+) AAGAT(A/G)ACACT downstream-variant-500B
rs810272 -- 69,612,396(+) AAATT(C/T)GGATG upstream-variant-2KB
rs2920838 -- 69,611,538(-) TCTTG(A/G)GCCCA upstream-variant-2KB
rs7136503 -- 69,608,338(+) TCTAG(G/T)TTAGC downstream-variant-500B

Relevant External Links for LRRC10 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for LRRC10 Gene

Disorders for LRRC10 Gene

Relevant External Links for LRRC10

Genetic Association Database (GAD)
genes like me logo Genes that share disorders with LRRC10: view

No data available for UniProtKB/Swiss-Prot for LRRC10 Gene

Publications for LRRC10 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. Molecular cloning and expression of HRLRRP, a novel heart-restricted leucine-rich repeat protein. (PMID: 14751244) Nakane T. … Chiba S. (Biochem. Biophys. Res. Commun. 2004) 2 3
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. Many sequence variants affecting diversity of adult human height. (PMID: 18391951) Gudbjartsson D.F. … Stefansson K. (Nat. Genet. 2008) 3 48
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for LRRC10 Gene

Sources for LRRC10 Gene

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