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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

LRPAP1 Gene

protein-coding   GIFtS: 63
GCID: GC04M003508

Low Density Lipoprotein Receptor-Related Protein Associated...

(Previous name: low density lipoprotein-related protein-associated protein...)
(Previous symbol: A2MRAP)
Alzheimer's & Parkinson's Diseases Congress
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Low Density Lipoprotein Receptor-Related Protein Associated Protein
11 2
     MRAP2
A2MRAP1 2 3 5     alpha-2-MRAP2
Low Density Lipoprotein-Related Protein-Associated Protein 1
(Alpha-2-Macroglobulin Receptor-Associated Protein 1)1 2
     Alpha-2-Macroglobulin Receptor-Associated Protein2
Low Density Lipoprotein Receptor-Related Protein-Associated Protein 12 3     Alpha-2-Macroglobulin Receptor-Associated Protein 12
RAP2 3     Lipoprotein Receptor Associated Protein2
A2RAP2     Alpha-2-MRAP3
HBP442     

External Ids:    HGNC: 67011   Entrez Gene: 40432   Ensembl: ENSG000001639567   OMIM: 1042255   UniProtKB: P305333   

Export aliases for LRPAP1 gene to outside databases

Previous GC identifers: GC04M003517 GC04M003420 GC04M003545 GC04M003551


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for LRPAP1 Gene: 
LRPAP1 (low density lipoprotein receptor-related protein associated protein 1) is a protein-coding gene. Diseases associated with LRPAP1 include von willebrand's disease, and biliary tract cancer. GO annotations related to this gene include heparin binding and low-density lipoprotein particle receptor binding.

UniProtKB/Swiss-Prot: AMRP_HUMAN, P30533
Function: Interacts with LRP1/alpha-2-macroglobulin receptor and glycoprotein 330

Gene Wiki entry for LRPAP1 (LDL-receptor-related protein associated protein) Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000004.11  NC_018915.2  NT_006051.18  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the LRPAP1 gene promoter:
         ER-alpha   AML1a   Sp1   YY1   STAT3   FOXO1a   FOXO1   En-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidLRPAP1 promoter sequence
   Search SABiosciences Chromatin IP Primers for LRPAP1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat LRPAP1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 4p16.3   Ensembl cytogenetic band:  4p16.3   HGNC cytogenetic band: 4p16.3

LRPAP1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
LRPAP1 gene location

GeneLoc information about chromosome 4         GeneLoc Exon Structure

GeneLoc location for GC04M003508:  view genomic region     (about GC identifiers)

Start:
3,505,324 bp from pter      End:
3,534,286 bp from pter
Size:
28,963 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: AMRP_HUMAN, P30533 (See protein sequence)
Recommended Name: Alpha-2-macroglobulin receptor-associated protein precursor  
Size: 357 amino acids; 41466 Da
Subunit: Present on cell surface forming a complex with the alpha-2-macroglobulin receptor heavy and light chains.
Binds LRP1B; binding is followed by internalization and degradation
Subcellular location: Endoplasmic reticulum. Cytoplasm. Cell surface. Note=Intracellular and associated with cell
surface receptors. Found in the endoplasmic reticulum
6/9 PDB 3D structures from and Proteopedia for LRPAP1 (see all 9):
1LRE (3D)        1NRE (3D)        1OP1 (3D)        1OV2 (3D)        2FCW (3D)        2FTU (3D)    
Secondary accessions: D3DVR9 Q2M310 Q53HQ3 Q53HS6

Explore the universe of human proteins at neXtProt for LRPAP1: NX_P30533

Explore proteomics data for LRPAP1 at MOPED 

Post-translational modifications:

  • UniProtKB: N-glycosylated
  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_P30533

  • LRPAP1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    LRPAP1 Protein Expression
    REFSEQ proteins: NP_002328.1  
    ENSEMBL proteins: 
     ENSP00000421922   ENSP00000421648  

    Human Recombinant Protein Products for LRPAP1: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    R&D Systems Recombinant & Natural Proteins for LRPAP1 (LRPAP)
    Enzo Life Sciences proteins for LRPAP1
    OriGene Purified Protein for LRPAP1
    OriGene Protein Over-expression Lysate for LRPAP1
    OriGene MassSpec for LRPAP1 
    OriGene Custom Protein Services for LRPAP1
    GenScript Custom Purified and Recombinant Proteins Services for LRPAP1
    Novus Biologicals LRPAP1 Proteins
    Novus Biologicals LRPAP1 Lysate
    Sino Biological Recombinant Protein for LRPAP1
    Sino Biological Cell Lysate for LRPAP1 
    ProSpec Recombinant Protein for LRPAP1
    Cloud-Clone Corp. Proteins for LRPAP1 

    Gene Ontology (GO): 5/7 cellular component terms (GO ID links to tree view) (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576extracellular region IDA8083232
    GO:0005783endoplasmic reticulum IDA--
    GO:0005886plasma membrane IDA16263759
    GO:0009986cell surface IEA--
    GO:0016021integral to membrane TAS1712782

    LRPAP1 for ontologies           About GeneDecksing



    LRPAP1 Antibody Products: 
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    Abcam antibodies for LRPAP1
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    LSBio Antibodies in human, mouse, rat for LRPAP1 

    Assay Products for LRPAP1: 
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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    2 InterPro protein domains:
     IPR010483 Alpha_2_MRAP_C
     IPR009066 MG_RAP_rcpt_1

    Graphical View of Domain Structure for InterPro Entry P30533

    ProtoNet protein and cluster: P30533

    1 Blocks protein domain: IPB009066 Alpha-2-macroglobulin receptor-associated protein

    UniProtKB/Swiss-Prot: AMRP_HUMAN, P30533
    Similarity: Belongs to the alpha-2-MRAP family


    LRPAP1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: AMRP_HUMAN, P30533
    Function: Interacts with LRP1/alpha-2-macroglobulin receptor and glycoprotein 330

         Genatlas biochemistry entry for LRPAP1:
    low density lipoprotein receptor related protein,associated protein 1

         Gene Ontology (GO): 5/7 molecular function terms (GO ID links to tree view) (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004873asialoglycoprotein receptor activity TAS2229028
    GO:0008201heparin binding IEA--
    GO:0035473lipase binding IEA--
    GO:0048019receptor antagonist activity IDA8083232
    GO:0050750low-density lipoprotein particle receptor binding IDA16263759
         
    LRPAP1 for ontologies           About GeneDecksing


    Phenotypes:
         9 MGI mutant phenotypes (inferred from 2 alleles(MGI details for Lrpap1):
     behavior/neurological  endocrine/exocrine gland  homeostasis/metabolism  mortality/aging  nervous system 
     normal  other  renal/urinary system  reproductive system 

    LRPAP1 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-outs for LRPAP1: Lrpap1tm1Vln Lrpap1tm1Her

       inGenious Targeting Laboratory - Custom generated mouse model solutions for LRPAP1 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for LRPAP1

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for LRPAP1 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for LRPAP1 

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat LRPAP1
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    SwitchGear 3'UTR luciferase reporter plasmidLRPAP1 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for LRPAP1
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    Gene Editing
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    Clone
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    DNA2.0 Custom Codon Optimized Gene Synthesis Service for LRPAP1
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                         Customized lentivirus expression plasmids for stable overexpression of LRPAP1 

    Cell Line
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    Search LifeMap BioReagents cell lines for LRPAP1
    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for LRPAP1


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for LRPAP1 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Signaling events mediated by the Hedgehog family
    Signaling events mediated by the Hedgehog family
    2Reelin signaling pathway
    Reelin signaling pathway
    3Lissencephaly gene (LIS1) in neuronal migration and development
    Lissencephaly gene (LIS1) in neuronal migration and development


    3 BioSystems Pathways for LRPAP1
        Signaling events mediated by the Hedgehog family
    Lissencephaly gene (LIS1) in neuronal migration and development
    Reelin signaling pathway



    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for LRPAP1

    5/28 Interacting proteins for LRPAP1 (P305332, 3) via UniProtKB, MINT, STRING, and/or I2D (see all 28)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    POLA2Q141812, 3MINT-63655 I2D: score=5 
    RTN4Q9NQC32, 3MINT-63654 I2D: score=5 
    PPM1GO153552, 3MINT-63653 I2D: score=4 
    CWC25Q9NXE83I2D: score=4 
    LRP1Q079543I2D: score=4 
    About this table

    Gene Ontology (GO): 5/6 biological process terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006457protein folding TAS8654360
    GO:0010916negative regulation of very-low-density lipoprotein particle clearance IDA8083232
    GO:0016192vesicle-mediated transport TAS8654360
    GO:0032091negative regulation of protein binding IDA8083232
    GO:1900116extracellular negative regulation of signal transduction IDA8083232

    LRPAP1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    LRPAP1 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for LRPAP1 (AMRP)

    10/13 Novoseek inferred chemical compound relationships for LRPAP1 gene (see all 13)    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    exotoxin-a 58.2 3 10326762 (1), 8694779 (1)
    mannan 31.6 1 7579446 (1)
    heparin 30.2 20 11382778 (6), 9253767 (2), 2229028 (2), 12637503 (1) (see all 5)
    lovastatin 20.6 1 7822276 (1)
    suramin 20.3 2 11604390 (2)
    mannose 18.5 1 7579446 (1)
    lysine 12 8 15025528 (3), 12637503 (2)
    cholesterol 0 3 17987404 (1), 9030194 (1), 16704534 (1)
    sucrose 0 1 8322889 (1)
    lipid 0 2 12394648 (1), 18721259 (1)

    Search CenterWatch for drugs/clinical trials and news about LRPAP1 / AMRP

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for LRPAP1 gene: 
    NM_002337.3  

    Unigene Cluster for LRPAP1:

    Low density lipoprotein receptor-related protein associated protein 1
    Hs.40966  [show with all ESTs]
    Unigene Representative Sequence: NM_002337
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000500728(uc003ghh.4) ENST00000296325 ENST00000515119 ENST00000509198


    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat LRPAP1
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate LRPAP1
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    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
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    GenScript: all cDNA clones in your preferred vector: LRPAP1 (NM_002337)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for LRPAP1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat LRPAP1
    Sirion Biotech Customized lentivirus for stable overexpression of LRPAP1 
                         Customized lentivirus expression plasmids for stable overexpression of LRPAP1 
    Primer
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat LRPAP1
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat LRPAP1

    Additional mRNA sequence: 

    AF085973.1 AK128751.1 AK222504.1 AK222527.1 AK292321.1 AK311600.1 AK312698.1 AL365520.1 
    AL365522.1 BC006574.2 BC007841.1 BC013950.2 BC018955.2 BC105074.1 BC112067.1 BX647984.1 
    M63959.1 

    21 DOTS entries:

    DT.91679654  DT.450524  DT.100879558  DT.95104282  DT.311312  DT.91696992  DT.422641  DT.97858164 
    DT.100810443  DT.100879555  DT.100879544  DT.80100088  DT.92450722  DT.100719826  DT.100804237  DT.100879568 
    DT.121225776  DT.40123802  DT.40304725  DT.80100089  DT.95104287 

    24/696 AceView cDNA sequences (see all 696):

    BQ723211 W81715 CR607197 BQ434613 BX381548 AL577900 H98116 BQ668698 
    AI151446 BX399454 BU579630 BQ575656 CR591537 CD107520 CB157694 CB129347 
    AA311422 BQ675077 CR614498 BE275512 AW514873 BM711920 CR596948 AI815082 

    GeneLoc Exon Structure

    5/8 Alternative Splicing Database (ASD) splice patterns (SP) for LRPAP1 (see all 8)    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3a · 3b ^ 4a · 4b · 4c ^ 5 ^ 6a · 6b ^ 7a · 7b · 7c ^ 8 ^ 9 ^ 10 ^ 11
    SP1:              -     -           -                                               -     -                     
    SP2:              -     -           -                       -     -     -           -     -                     
    SP3:              -     -           -                                                                           
    SP4:              -     -           -           -     -                                                         
    SP5:              -     -                                                                                       


    ECgene alternative splicing isoforms for LRPAP1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    LRPAP1 expression in normal human tissues (normalized intensities)      LRPAP1 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CACAGAGTCC
    LRPAP1 Expression
    About this image


    LRPAP1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/7 selected tissues (see all 7) fully expand
     
     Brain (Nervous System)    fully expand to see all 4 entries
             Cerebral Cortex
             brain/forebrain/telencephalon   
     
     Neural Tube (Nervous System)    fully expand to see all 2 entries
             Metencephalon
     
     Trophoblast (Extraembryonic Tissues)
             Mural Trophectoderm Cells Mural Trophectoderm
     
     Gut Tube (Gastrointestinal Tract)
             Foregut
     
     Nose (Sensory Organs)
             sensory organ/nose/nasal cavity   

    See LRPAP1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for LRPAP1

    SOURCE GeneReport for Unigene cluster: Hs.40966
        SABiosciences Expression via Pathway-Focused PCR Array including LRPAP1: 
              Lipoprotein Signaling & Cholesterol Metabolism in human mouse rat

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    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat LRPAP1
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for LRPAP1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for LRPAP1 gene from 7/15 species (see all 15)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Lrpap11 , 5 low density lipoprotein receptor-related protein associated more1, 5 79.55(n)1
    76.19(a)1
      5 (18.01 cM)5
    169761  NM_013587.21  NP_038615.21 
     350914905 
    chicken
    (Gallus gallus)
    Aves LRPAP11 low density lipoprotein receptor-related protein associated more 67.88(n)
    68.69(a)
      395936  NM_205062.1  NP_990393.1 
    lizard
    (Anolis carolinensis)
    Reptilia LRPAP16
    Uncharacterized protein
    68(a)
    1 ↔ 1
    GL343585.1(442453-445917)
    African clawed frog
    (Xenopus laevis)
    Amphibia LOC3986432 hypothetical protein LOC398643 72.93(n)    BC054293.1 
    zebrafish
    (Danio rerio)
    Actinopterygii lrpap12 low density lipoprotein receptor-related protein associated more 72.59(n)   333939  BC049517.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG85071 , 3 CG85071 35(a)3
    50.55(n)1
    36.56(a)1
      85E93
    412051  NM_141693.21  NP_649950.11 
    worm
    (Caenorhabditis elegans)
    Secernentea C15C8.41 Protein C15C8.4 42.97(n)
    33.59(a)
      179745  NM_073786.3  NP_506187.2 


    ENSEMBL Gene Tree for LRPAP1 (if available)
    TreeFam Gene Tree for LRPAP1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    815/1041 SNPs in LRPAP1 are shown (see all 1041)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 4 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs348975111,2
    Cuntested13526636(-) CCTCAA/GTGGTA 2 N S mis11Minor allele frequency- G:0.01NA 76
    rs755795991,2
    F--3504859(+) CACCCC/GCTCGG 1 -- ds50011Minor allele frequency- G:0.04EA 120
    rs28580241,2
    C,F,A,H--3504863(+) CCCTCT/GGTTCA 1 -- ds500111Minor allele frequency- G:0.39NA WA CSA EA 374
    rs1422912371,2
    --3504892(+) CTCTCA/GGCACC 1 -- ds50010--------
    rs1512683151,2
    --3504902(+) CCGTGC/TCACAG 1 -- ds50010--------
    rs1152445971,2
    F--3504933(+) CGAGGC/TGAGGC 1 -- ds50011Minor allele frequency- T:0.02WA 118
    rs1393305721,2
    --3504958(+) TGGCAA/CCGCAC 1 -- ds50010--------
    rs1500336261,2
    C--3504969(+) ACTCAC/GGCCCC 1 -- ds50010--------
    rs1453586171,2
    --3504980(+) ACACAC/TGGATG 1 -- ds50010--------
    rs1425919531,2
    --3505008(+) AGCTAC/TCAGCA 1 -- ds50010--------
    rs100280981,2
    C,F,A,H--3505067(+) CCAACG/ACTGGC 1 -- ds50017Minor allele frequency- A:0.28NA WA EA 370
    rs1926117831,2
    --3505075(+) GGCACA/GGGTGA 1 -- ds50010--------
    rs1162627191,2
    C,F--3505096(+) CTCTGG/AGAATA 1 -- ds50011Minor allele frequency- A:0.03NA 120
    rs1844906101,2
    --3505104(+) ATACCC/TGTGCC 1 -- ds50010--------
    rs1890211121,2
    --3505105(+) TACCCA/GTGCCA 1 -- ds50010--------
    rs716082841,2
    C,F--3505161(+) AAGCTC/TGTACA 1 -- ds50016Minor allele frequency- T:0.14NA WA 246
    rs26994041,2
    C,F,O,A,H--3505162(-) ATGTAC/TGAGCT 1 -- ds500111Minor allele frequency- T:0.32NA WA CSA EA 374
    rs1469104291,2
    --3505179(+) GGCCCA/GTCTCT 1 -- ds50010--------
    rs622727001,2
    C,F--3505193(+) TGTGAC/TGTGCA 1 -- ds50015Minor allele frequency- T:0.13NA WA 244
    rs679306541,2
    C--3505206(-) GCAGG-/AGGCTGAG 1 -- ds50012Minor allele frequency- AGG:0.25NA 4
    rs1153535781,2
    F--3505233(+) TCCCCC/TCCGCA 1 -- ds50011Minor allele frequency- T:0.01WA 118
    rs780518751,2
    C,F--3505235(+) CCCCCC/GGCAGT 1 -- ds50012Minor allele frequency- G:0.13CSA WA 120
    rs1477631171,2
    --3505246(+) TTCCTA/GAAGTG 1 -- ds50010--------
    rs1932964001,2
    --3505374(+) ATGGCA/GGTGAA 1 -- ut310--------
    rs34681,2
    C,F,O,A,H--3505448(+) CTCACG/ACGCTT 1 -- ut3126Minor allele frequency- A:0.33MN NS EA NA WA 2964
    rs1849088461,2
    --3505449(+) TCACGC/TGCTTG 1 -- ut310--------
    rs1891893871,2
    --3505470(+) CAACAA/GCAGAC 1 -- ut310--------
    rs1411118381,2
    --3505476(+) CAGACA/GACAGA 1 -- ut310--------
    rs1434614171,2
    --3505490(+) TTCCAA/TCTCCA 1 -- ut310--------
    rs1816420621,2
    --3505509(+) AGGCTA/GGGGTA 1 -- ut310--------
    rs560277441,2
    C--3505604(+) GAAGGT/CAGAAA 1 -- ut312Minor allele frequency- C:0.10WA 120
    rs1171352971,2
    F--3505636(+) AGGGGC/TCCAGG 1 -- ut311Minor allele frequency- T:0.02EA 120
    rs1480074031,2
    C--3505648(+) AGGTCA/GTGAGC 1 -- ut310--------
    rs1407808541,2
    --3505657(+) GCGCCA/CAGCAC 1 -- ut310--------
    rs1859760811,2
    --3505733(+) CAGCAA/GGGTGG 1 -- ut310--------
    rs562982181,2
    --3505750(+) CACCAG/TGCTCC 1 -- ut310--------
    rs1386908471,2
    --3505768(+) CCTCAC/GGTGAG 1 -- ut310--------
    rs117230711,2
    C,F,H--3505847(+) CAACCC/ACCTCG 1 -- ut317Minor allele frequency- A:0.13NA WA CSA EA 366
    rs1898456541,2
    --3505890(+) ACCTGA/GCAAGA 1 -- ut310--------
    rs1811196741,2
    C--3505898(+) AGATCC/TGGCCT 1 -- ut310--------
    rs1418146621,2
    --3505962(+) AACCCA/GGTCTC 1 -- ut310--------
    rs99996971,2
    C,F--3505989(+) TCTCCA/GGGAGG 1 -- ut315Minor allele frequency- G:0.14NA WA 244
    rs1862443671,2
    --3506106(+) GCAGCC/TGAGGT 1 -- ut310--------
    rs1907684361,2
    --3506130(+) GAGGTC/GAGGAA 1 -- ut310--------
    rs563582671,2
    C,F--3506182(+) CTAAAA/GACAGA 1 -- ut318Minor allele frequency- G:0.31WA NA CSA EA 366
    rs68360641,2
    C,F--3506214(+) gctcaC/Tgccta 1 -- ut311Minor allele frequency- T:0.50WA 2
    rs1381506331,2
    --3506303(+) GAAACA/CCTGTC 1 -- ut310--------
    rs28580251,2
    C,F--3506440(+) CCATTG/CCACTG 1 -- ut315Minor allele frequency- C:0.50NA WA 10
    rs2002427821,2
    --3506461(+) ATTGA-/GTGATTC 1 -- ut310--------
    rs711801901,2
    C--3506491(-) TTTGG-/T/TTT 
            
    TTTTT
    2 -- ut311NA 2
    rs1447011761,2
    --3506653(+) TGGGCA/GACAGA 1 -- ut310--------
    rs793806561,2
    C--3506681(+) GAAAAA/TAATAA 1 -- ut310--------
    rs2010576701,2
    --3506681(+) AAAAA-/AATAATAA 1 -- cds10--------
    rs772052351,2
    C--3506684(+) AAAAAG/TAAATA 1 -- ut310--------
    rs347650331,2
    C--3506685(+) AAATA-/AA    
       G
    /GAA
    AATAA
    2 -- cds10--------
    rs730809861,2
    C,F--3506762(+) GACTTT/CAGGGA 1 -- ut312Minor allele frequency- C:0.07WA 120
    rs28580261,2
    C,F,A,H--3506811(+) TACCAC/TGCACG 1 -- ut3117Minor allele frequency- T:0.15NS EA WA NA CSA 765
    rs1485238621,2
    --3506847(+) ACGCAC/TGCAGC 1 -- ut310--------
    rs1841594021,2
    C--3506867(+) CTGGCA/TAAGCT 1 -- ut310--------
    rs1428729771,2
    --3506893(+) GCTCAC/TGGACA 1 -- ut310--------
    rs28580271,2
    C,F,O,A,H--3506933(+) AGCCCG/AGCTCG 1 -- ut3115Minor allele frequency- A:0.20NA EA WA 738
    rs1120215001,2
    C,F--3506977(+) GCAGCG/AGCTGC 1 -- ut312Minor allele frequency- A:0.08WA 120
    rs730809911,2
    C,F--3507121(+) TGGGAT/AGGAGT 1 -- ut311Minor allele frequency- A:0.50WA 2
    rs737939651,2
    C,F--3507180(+) GCATGG/ACTCCG 1 -- ut311Minor allele frequency- A:0.50WA 2
    rs168444881,2
    C,F--3507187(+) TCCGAG/ACGGCA 1 -- ut315Minor allele frequency- A:0.08NA WA 260
    rs1829590941,2
    --3507205(+) CACACC/TGCGCA 1 -- ut310--------
    rs1472917151,2
    --3507218(+) TGCCTA/GTGCCT 1 -- ut310--------
    rs28580281,2
    C,F,H--3507248(+) CGGAAG/CGTCCC 1 -- ut3112Minor allele frequency- C:0.24NA WA CSA EA 377
    rs1409392431,2
    --3507320(+) CAGCCC/TACACG 1 -- ut310--------
    rs1448606571,2
    --3507324(+) CCACAC/GGCCTC 1 -- ut310--------
    rs1479514401,2
    C--3507381(+) CCAAGA/CCCGTC 1 -- ut310--------
    rs1406532731,2
    --3507383(+) AAGACC/TGTCTA 1 -- ut310--------
    rs1498670391,2
    C--3507386(+) ACCGTA/CTATAC 1 -- ut310--------
    rs1490510421,2
    --3507480(+) AGACCA/GTCTAT 1 -- ut310--------
    rs772983951,2
    C,F--3507521(+) TGCTGG/TGGAGG 1 -- ut311Minor allele frequency- T:0.05NA 120
    rs1430862861,2
    --3507567(+) CTGGGC/TAGAGA 1 -- ut310--------
    rs596141851,2
    C--3507742(+) AAAAA-/ATCACT 1 -- ut311Minor allele frequency- A:0.50CSA 2
    rs747179411,2
    C--3507808(+) TTTTTG/TAGACA 1 -- ut311Minor allele frequency- T:0.50NA 2
    rs788690141,2
    C,F--3507852(+) TGGCAC/TGATTT 1 -- ut312Minor allele frequency- T:0.03NA EA 240
    rs782944841,2
    C,F--3507996(+) TGATGC/TTGGCC 1 -- ut311Minor allele frequency- T:0.50WA 2
    rs1872157931,2
    --3508000(+) GTTGGC/GCAGGC 1 -- ut310--------
    rs1929364891,2
    C--3508122(+) TGAGGC/TGAAGT 1 -- ut310--------
    rs1829711571,2
    --3508151(+) CCGGAG/TTGCAA 1 -- ut310--------
    rs593330611,2
    C,F--3508173(+) CGGCTC/TACTGC 1 -- ut311Minor allele frequency- T:0.50WA 2
    rs1880585511,2
    --3508288(+) GAGATA/GGGGTT 1 -- ut310--------
    rs1922422301,2
    C--3508334(+) CCTCAC/TGTGAT 1 -- ut310--------
    rs68201911,2
    C,F--3508342(+) gatccG/Acccac 1 -- ut313Minor allele frequency- A:0.50NA WA CSA 6
    rs1836560761,2
    --3508405(+) GCTCGA/GGCTGT 1 -- ut310--------
    rs1381190541,2
    --3508421(+) AGAGGA/CTATAT 1 -- ut310--------
    rs1895438741,2
    --3508454(+) TCCCCA/GAAGTC 1 -- ut310--------
    rs559161361,2
    C,F--3508591(+) AGGATC/TGGAAA 1 -- ut314Minor allele frequency- T:0.42NA EA 244
    rs26994031,2
    C,F,A,H--3508671(-) gagccA/Gccaca 1 -- ut3113Minor allele frequency- G:0.35NS EA NA WA CSA 781
    rs1923463561,2
    --3508701(+) CACTCC/TGCGAG 1 -- ut310--------
    rs1845595901,2
    --3508727(+) TCACTG/TGAGAC 1 -- ut310--------
    rs1899463501,2
    --3508742(+) ACTCCA/GAGACC 1 -- ut310--------
    rs1997282001,2
    --3508780(+) TCTAT-/AAAAAA 1 -- ut310--------
    rs1815918171,2
    --3508789(+) AAAAAA/CCTTTT 1 -- ut310--------
    rs1508121941,2
    --3508865(+) AGGCTA/CGCTTG 1 -- ut310--------
    rs1381625851,2
    --3508917(+) CTGCAA/CTCCAA 1 -- ut310--------
    rs1495798081,2
    --3508924(+) CCAAGC/GCTGTG 1 -- ut310--------
    rs2008133211,2
    --3508947(+) GACTC-/AAAAAA 1 -- ut310--------
    rs284101661,2
    C,F--3509097(+) AAAACG/TAAAAC 1 -- ut315Minor allele frequency- T:0.33NA CSA WA EA 362
    rs1846527211,2
    --3509134(+) TTTTTG/TTTACT 1 -- ut310--------
    rs285475701,2
    C,F--3509153(+) CCTCAA/GTTGCA 1 -- ut317Minor allele frequency- G:0.34NA CSA WA EA 366
    rs106253291,2
    C--3509209(+) ATTTATACAT/
            
    TACAT
    1 -- ut311Minor allele frequency- -:0.50CSA 2
    rs339634221,2
    C--3509210(+) TTTAT-/TACAT 
            
    ACATT
    1 -- ut310--------
    rs1137817521,2
    C--3509215(+) TACATC/TATCAT 1 -- ut311Minor allele frequency- T:0.50NA 2
    rs28580291,2
    C,F,O,A,H--3509259(+) TACCTC/TGTCCA 1 -- ut3110Minor allele frequency- T:0.31NA WA CSA EA 373
    rs716082851,2
    C,F--3509260(+) ACCTCG/ATCCAT 1 -- ut316Minor allele frequency- A:0.14NA WA 246
    rs1420519741,2
    C--3509321(+) GTAGA-/CCAAGTTTTT
    AACTGTATTATC
    CCATT
    1 -- ut310--------
    rs770814411,2
    F--3509401(+) AACAAG/TGACAG 1 -- ut311Minor allele frequency- T:0.03WA 118
    rs1408472471,2
    --3509403(+) CAAGGA/GCAGCA 1 -- ut310--------
    rs1448217981,2
    --3509418(+) GAACAC/GAAAAT 1 -- ut310--------
    rs1895884691,2
    --3509481(+) AACAAC/TAGAAA 1 -- ut310--------
    rs343363831,2
    C--3509483(+) AAAAAA/-TCAAT 1 -- ut311Minor allele frequency- -:0.00NA 2
    rs117275591,2
    H--3509517(+) GGTTTC/TTTTGG 1 -- ut310--------
    rs1809094471,2
    --3509599(+) GAGCAC/GGAATG 1 -- ut310--------
    rs1475215221,2
    --3509680(+) TTCTGC/TGACAA 1 -- ut310--------
    rs1849736631,2
    --3509738(+) CCTCAC/TGTCTT 1 -- ut310--------
    rs1909047221,2
    --3509743(+) TGTCTC/TTTTTT 1 -- ut310--------
    rs117293691,2
    C,F,H--3509962(+) tcctgC/Acctca 1 -- ut315Minor allele frequency- A:0.25NA WA CSA 8
    rs1408654161,2
    C--3510237(+) CATCC-/AAAGCC 1 -- ut310--------
    rs754580811,2
    C,F--3510269(+) CTACAC/TAGGAG 1 -- ut312Minor allele frequency- T:0.08NA 122
    rs17307661,2
    C--3510304(-) GGCCAG/AATGAG 1 -- ut316Minor allele frequency- A:0.44MN NA WA EA 546
    rs1429859041,2
    C--3510331(+) AATGCA/GCCATG 1 -- ut310--------
    rs1509217841,2
    C--3510368(+) AGGTCA/GTCTTG 1 -- ut310--------
    rs795953151,2
    C,F--3510415(+) GGTAAG/CGAAGT 1 -- ut312Minor allele frequency- C:0.08NA 122
    rs1817538311,2
    --3510460(+) CAGCTG/TACCAC 1 -- ut310--------
    rs1871479561,2
    --3510462(+) GCTGAA/CCACAT 1 -- ut310--------
    rs31841,2
    C,F,O,A,H--3510514(-) CAGGCG/AGAAGA 1 -- ut3129Minor allele frequency- A:0.29NS EA NA WA CSA 2486
    rs1141267111,2
    C,F--3510581(+) CGAGAC/TTGGGA 1 -- ut311Minor allele frequency- T:0.02WA 118
    rs1915782451,2
    --3510587(+) TGGGAA/GTAAGA 1 -- ut310--------
    rs31821,2
    C,F,A,H--3510598(-) GCGCTT/CGCTAA 1 -- ut3137Minor allele frequency- C:0.34EA NA NS WA CSA 3410
    rs1406884011,2
    --3510604(+) AGCGCC/TGGCTC 1 -- ut310--------
    rs31831,2
    C,F,O,A,H--3510615(-) ACTGGC/TGAGGT 1 -- ut3128Minor allele frequency- T:0.29MN NS EA NA WA CSA 2716
    rs1833876751,2
    --3510642(+) GCACAA/GACTGA 1 -- ut310--------
    rs1140487701,2
    C,F--3510646(+) AGACTG/AACAAG 1 -- ut311Minor allele frequency- A:0.01NA 120
    rs1431950821,2
    --3510670(+) ACTGTC/TAGACA 1 -- ut310--------
    rs1466939941,2
    C--3510684(+) GACACA/GCGTGT 1 -- ut310--------
    rs1162139461,2
    F--3510685(+) ACACGC/TGTGTG 1 -- ut311Minor allele frequency- T:0.01WA 118
    rs1879283501,2
    --3510729(+) GCCATA/GGCCAA 1 -- ut310--------
    rs1913046281,2
    --3510738(+) AAGGCA/GGGAGT 1 -- ut310--------
    rs1403101511,2
    --3510768(+) CACCAC/TGCACA 1 -- ut310--------
    rs100019751,2
    C,F,A--3510769(+) ACCACG/ACACAG 1 -- ut316Minor allele frequency- A:0.13NA WA 246
    rs1823018781,2
    --3510789(+) GAAATA/TAAAAT 1 -- ut310--------
    rs1866269171,2
    --3510800(+) ACACAA/GTCCTC 1 -- ut310--------
    rs1454094221,2
    C--3510847(+) AAAACA/CTGCCA 1 -- ut310--------
    rs1926412951,2
    --3510908(+) ACTCAA/GTACCT 1 -- ut310--------
    rs1849017881,2
    --3510921(+) AGTCAC/TACATG 1 -- ut310--------
    rs586736261,2
    C--3510925(+) ATACAC/TGGCAG 1 -- ut310--------
    rs1166198321,2
    F--3510926(+) TACATG/AGCAGT 1 -- ut311Minor allele frequency- A:0.02WA 118
    rs1887712941,2
    --3510938(+) AACGCA/GTGGAC 1 -- ut310--------
    rs17307651,2
    C,F,H--3510954(-) CTCAAC/TAGTCT 1 -- ut3113Minor allele frequency- T:0.29EA NS NA WA CSA 1111
    rs100021081,2
    C,F,A,H--3510957(+) CTGTTG/AAGACG 1 -- ut317Minor allele frequency- A:0.32NS NA WA CSA 105
    rs68214001,2
    C,A,H--3511010(+) GACTGC/TTGAGA 1 -- ut312Minor allele frequency- T:0.33NA CSA 3
    rs17307641,2
    C,F,A,H--3511065(-) TCTCAG/ACAGTC 1 -- ut319Minor allele frequency- A:0.33NA 18
    rs97615831,2
    C,F--3511120(+) GACTGC/TTGAGA 1 -- ut312Minor allele frequency- T:0.50NA 4
    rs16105791,2
    C--3511175(-) TCTCAG/ACAGTC 1 -- ut311Minor allele frequency- A:0.50NA 2
    rs1386316111,2
    C--3511230(+) GACTGC/TTGAGA 1 -- ut310--------
    rs622727011,2
    C--3511285(+) GACTGC/TTGAGA 1 -- ut311Minor allele frequency- T:0.50NA 2
    rs716082861,2
    C,F--3511340(+) GACTGC/TTGAGA 1 -- ut313Minor allele frequency- T:0.33NA 6
    rs348988171,2
    C,F--3511395(+) GACTGT/CTGAGA 1 -- ut313Minor allele frequency- C:0.33NA 6
    rs17944391,2
    C--3511441(+) GACACC/TGGAGA 1 -- ut313Minor allele frequency- T:0.00NA 6
    rs100115451,2
    C,F,A--3511450(+) GACTGT/CTGAGA 1 -- ut313Minor allele frequency- C:0.33NA 6
    rs100209941,2
    C,F,A--3511496(+) GACACC/TGGAGA 1 -- ut313Minor allele frequency- T:0.33NA 6
    rs100138911,2
    C,F,A--3511505(+) GACTGT/CTGAGA 1 -- ut313Minor allele frequency- C:0.33NA 6
    rs100210141,2
    C,F--3511551(+) GACACC/TGGAGA 1 -- ut313Minor allele frequency- T:0.33NA 6
    rs1129196051,2
    C--3511570(+) ACGCCA/GACTGG 1 -- ut310--------
    rs1851423911,2
    --3511597(+) CAACGA/CGTGGA 1 -- ut310--------
    rs1431112631,2
    --3511622(+) AAGACA/GCCGAT 1 -- ut310--------
    rs1896749771,2
    --3511672(+) CAAAAA/CTGCGT 1 -- ut310--------
    rs107106871,2
    C,F--3511713(+) GCATGT/-TTTTT 1 -- ut313Minor allele frequency- -:0.50NA 6
    rs1810432521,2
    --3511777(+) AAACAA/GCCACA 1 -- ut310--------
    rs556547221,2
    C,F--3511791(+) ATCTTG/TAAAAA 1 -- ut311Minor allele frequency- T:0.50WA 2
    rs575371031,2
    C,F--3511943(+) CACTTG/AAGCCC 1 -- ut311Minor allele frequency- A:0.50WA 2
    rs353501831,2
    F--3511984(+) AACCCC/TGTCTC 1 -- ut311Minor allele frequency- T:0.50NA 4
    rs1496229621,2
    --3512079(+) GAGGCA/GAGGGG 1 -- ut310--------
    rs100144661,2
    C,F,A,H--3512137(+) tactgC/Tactcc 1 -- ut316Minor allele frequency- T:0.14NA WA 248
    rs1881263551,2
    --3512148(+) AGCCTA/GAGGGA 1 -- ut310--------
    rs1443777751,2
    --3512273(+) AAGCCC/TATGCA 1 -- ut310--------
    rs1820393751,2
    --3512296(+) AAAGTA/TAAGGG 1 -- ut310--------
    rs100146741,2
    C,F--3512336(+) GGAAAC/TGTACA 1 -- ut311Minor allele frequency- T:0.02WA 118
    rs755776961,2
    F--3512369(+) ACACGC/TGGCAC 1 -- ut311Minor allele frequency- T:0.01NA 120
    rs1488094561,2
    --3512392(+) CAGGCC/TGCCAC 1 -- ut310--------
    rs1871150591,2
    --3512393(+) AGGCCA/GCCACG 1 -- ut310--------
    rs731971251,2
    --3512428(+) TCCACA/GCAAAA 1 -- ut310--------
    rs1390789261,2
    C--3512469(+) TAAGC-/AGAT  
            
    AGATA
    1 -- ut310--------
    rs1920296861,2
    --3512479(+) ACACGC/GAGACA 1 -- ut310--------
    rs68185221,2
    C,F,A,H--3512489(+) ATACAC/GAGACG 1 -- ut3116Minor allele frequency- G:0.02NS EA NA WA 1640
    rs1818004161,2
    --3512518(+) GCCCAA/GAGCCA 1 -- ut310--------
    rs68480391,2
    C,F--3512529(+) TGCACG/TTGGAA 1 -- ut312Minor allele frequency- T:0.03WA 120
    rs17944231,2
    C,F,A,H--3512563(+) AGCTGC/TGGTGG 1 -- ut318Minor allele frequency- T:0.44NA WA EA 370
    rs1867730361,2
    --3512612(+) CGGAGC/TGGAGG 1 -- ut310--------
    rs1431547691,2
    C--3512644(+) AGTGCA/GCACCA 1 -- ut310--------
    rs17944241,2
    C,F,A,H--3512690(+) CTGGGC/TTTTTT 1 -- ut3114Minor allele frequency- T:0.26NA WA CSA EA 380
    rs1466680931,2
    C--3512850(+) CTAGTA/GTTCTC 1 -- ut310--------
    rs765982711,2
    F--3513038(+) CAACTG/CAAATA 1 -- ut311Minor allele frequency- C:0.50CSA 2
    rs1440539671,2
    --3513104(+) TACTAC/TACAGC 1 -- ut310--------
    rs17415561,2
    C,F,A,H--3513125(-) AGAAGC/TGTGTT 1 -- ut3125Minor allele frequency- T:0.28NS EA NA WA CSA 2347
    rs17415551,2
    C--3513205(-) TTCTGG/CTTCTT 1 -- ut314Minor allele frequency- C:0.15NA EA 244
    rs1902699291,2
    --3513218(+) CACCCA/CCCGCC 1 -- ut310--------
    rs1139604001,2
    C,F--3513254(+) ACAAAG/AGAACA 1 -- ut312Minor allele frequency- A:0.04WA 120
    rs1826345171,2
    --3513373(+) GGCAGA/CTCTCA 1 -- ut310--------
    rs1509752101,2
    --3513423(+) CGCCTG/TGTGGA 1 -- ut310--------
    rs1408211211,2
    --3513441(+) CCAGGC/TTCAAA 1 -- ut310--------
    rs1869679861,2
    --3513445(+) GTTCAA/GACACG 1 -- ut310--------
    rs787121381,2
    C--3513449(+) GGGAA-/GGGAA 
            
    CCACG
    1 -- ut310--------
    rs1897556731,2
    --3513474(+) GGACCC/GGGACC 1 -- ut310--------
    rs1835214951,2
    C--3513480(+) GGACCC/TGAGCC 1 -- ut310--------
    rs361010761,2
    C,F--3513570(+) CGCCCG/AGAGCC 1 -- ut312Minor allele frequency- A:0.50NA 4
    rs20144401,2
    C,F,A--3513621(+) CACGCC/TCGGAG 1 -- ut313Minor allele frequency- T:0.33NA 6
    rs38977061,2
    A--3513623(+) CGCTCA/GGAGCC 1 -- ut310--------
    rs286996061,2
    C--3513658(+) GACACG/AGGAAG 1 -- ut311Minor allele frequency- A:0.50NA 2
    rs131120541,2
    C--3513674(+) CACGCC/TCGGAG 1 -- ut313Minor allele frequency- T:0.17NA 6
    rs74420351,2
    C,A--3513701(+) TCCAGG/ACTCAG 1 -- ut311Minor allele frequency- A:0.50NA 2
    rs7318191,2
    C,F,A--3513711(+) GACACG/AGGAAG 1 -- ut312Minor allele frequency- A:0.50NA 4
    rs131120881,2
    C,F--3513727(+) CACGCC/TCGGAG 1 -- ut313Minor allele frequency- T:0.50NA WA 6
    rs131267921,2
    C,F--3513735(+) GAGCCG/AGACCC 1 -- ut312Minor allele frequency- A:0.50NA WA 4
    rs17944321,2
    C,F,A--3513754(+) TCCAGG/ACTCAG 1 -- ut315Minor allele frequency- A:0.30NA WA 10
    rs17307611,2
    C,F,A--3513780(-) CTCCGG/AGCGTG 1 -- ut312Minor allele frequency- A:0.50NA WA 4
    rs74369981,2
    A--3513781(+) ACGCTC/TGGAGC 1 -- ut310--------
    rs74420711,2
    C,F,A--3513788(+) GAGCCG/AGACCC 1 -- ut312Minor allele frequency- A:0.50NA WA 4
    rs20930981,2
    C,F--3513834(-) GCTCCA/GGGCGT 1 -- ut319Minor allele frequency- G:0.39NA WA EA 372
    rs1932263841,2
    --3513887(+) GGAGCC/TGGACC 1 -- ut310--------
    rs1115584131,2
    C,F--3513901(+) GCAACC/TGCCAG 1 -- ut311Minor allele frequency- T:0.50NA 2
    rs1127503201,2
    C,F--3513936(+) GCCTCC/TGTGGC 1 -- ut312Minor allele frequency- T:0.01NA EA 240
    rs1851839751,2
    --3513943(+) TGGCTA/GTCTCT 1 -- ut310--------
    rs1885055471,2
    --3514048(+) GAGAGG/TTGAAA 1 -- ut310--------
    rs622727021,2
    F--3514049(+) AGAGTC/TGAAAG 1 -- ut311Minor allele frequency- T:0.50NA 2
    rs7307481,2
    C,F--3514086(+) ACTGTC/ACACAG 1 -- ut318Minor allele frequency- A:0.16NA EA WA CSA 520
    rs1166229901,2
    F--3514133(+) CAAGCG/ACTCTT 1 -- ut311Minor allele frequency- A:0.01WA 118
    rs1918531111,2
    --3514227(+) GACGCA/GATCCC 1 -- ut310--------
    rs20771301,2
    C,F,A--3514229(+) CGCGAT/CCCCTT 1 -- ut3110Minor allele frequency- C:0.50NA EA CSA WA 1712
    rs17944381,2
    C,F,A--3514237(-) TGCTCG/TTGAAG 1 -- ut3113Minor allele frequency- T:0.26NA WA CSA EA 378
    rs99956851,2
    C--3514316(+) TCTATA/TTTTTA 1 -- ut310--------
    rs1390574511,2
    C--3514344(+) ATTTCC/TGGTGG 1 -- ut310--------
    rs777684791,2
    F--3514368(+) TTTTTT/AATGTA 1 -- ut312Minor allele frequency- A:0.04NA WA 120
    rs178482811,2
    C--3514414(-) CCAGCG/TGCTGT 1 -- ut31 ese30--------
    rs10495741,2
    C,F,A,H--3514539(-) CGTCGC/TGACAC 1 -- ut3122Minor allele frequency- T:0.36EA MN NS NA WA CSA 4024
    rs1139533971,2
    C--3514602(+) GCCCCA/TGCCAC 1 -- ut310--------
    rs556835541,2
    C--3514613(+) CCTGAC/TGGCGG 1 -- ut312Minor allele frequency- T:0.04WA 120
    rs1839835951,2
    --3514614(+) CTGACA/GGCGGG 1 -- ut310--------
    rs2001273651,2
    C--3514662(+) TTCACA/GCTGGC 1 -- ut310--------
    rs769836281,2
    C,F--3514668(+) CTGGCC/TTCTTC 1 -- ut311Minor allele frequency- T:0.03WA 118
    rs1882712521,2
    C--3514680(+) CTGCCA/GGGCTG 1 -- ut310--------
    rs18004951,2
    C,F--3514689(-) TGGGGA/GGCCCA 1 -- ut31 ese33Minor allele frequency- G:0.01NA WA EU 503
    rs67891,2
    C,F,A,H--3514695(-) AGGCAT/CTGGGG 1 -- ut3127Minor allele frequency- C:0.36MN EA NS WA NA CSA EU 4695
    rs1481208091,2
    C--3514696(+) CCCAAT/CGCCTT 1 -- ut311Minor allele frequency- C:0.00EU 489
    rs1419434821,2
    C--3514710(+) AGTTCA/GTTGTG 2 N syn10--------
    rs1438415601,2
    C,F--3514715(+) GTTGTG/CCCGAG 2 /H /D mis12Minor allele frequency- C:0.00NA EU 5285
    rs2008589801,2
    C--3514778(+) GAAACA/GTCTCA 1 -- int10--------
    rs1506774841,2
    --3514843(+) GGAGAC/TGCGCG 1 -- int10--------
    rs1144763571,2
    F--3514879(+) TGCACA/GTCTGA 1 -- int11Minor allele frequency- G:0.03WA 118
    rs17415531,2
    C,F,A,H--3514938(-) GTTAGC/TACTGA 1 -- int118Minor allele frequency- T:0.22NA EA WA CSA 744
    rs1912312031,2
    --3515044(+) TATTTA/GTTTAC 1 -- int10--------
    rs1843233541,2
    --3515106(+) CTCAGC/TTCACT 1 -- int10--------
    rs622727031,2
    C,F--3515148(+) TCCCAC/TCTCAG 1 -- int13Minor allele frequency- T:0.50NA 6
    rs1903868771,2
    --3515186(+) CCCACC/TGCCAC 1 -- int10--------
    rs1160325391,2
    C,F--3515217(+) TTTTGG/ATAGAG 1 -- int11Minor allele frequency- A:0.07NA 120
    rs1822185171,2
    --3515277(+) ATGATC/TCACCC 1 -- int10--------
    rs17415521,2
    C,F,H--3515318(-) TGGCTC/TACACC 1 -- int18Minor allele frequency- T:0.29NA WA CSA 17
    rs1461748181,2
    --3515464(+) CCAGAA/GCATCC 1 -- int10--------
    rs1869336631,2
    --3515511(+) CAGCCC/TAGCCT 1 -- int10--------
    rs763162561,2
    C--3515598(+) AGCCCG/ATGGCT 1 -- int14Minor allele frequency- A:0.04CSA WA NA 241
    rs1890512211,2
    --3515616(+) AATAAC/GTCACC 1 -- int10--------
    rs1813625241,2
    --3515633(+) CCCTTC/TTCTCA 1 -- int10--------
    rs1856364511,2
    --3515641(+) TCAGCA/GGCCCT 1 -- int10--------
    rs737939791,2
    C,F--3515708(+) AACACC/TGAGCT 1 -- int11Minor allele frequency- T:0.50WA 2
    rs1440079291,2
    C--3515718(+) TTTGCC/TGTGGT 1 -- int10--------
    rs37897401,2
    F--3515841(+) GCCACA/GGGCTG 1 -- int11Minor allele frequency- G:0.01EA 1494
    rs17944401,2
    C,F,A,H--3515928(+) CCTTTC/GCTATT 1 -- int117Minor allele frequency- G:0.25NS EA NA WA CSA 794
    rs1486508451,2
    --3515931(+) TTGCTA/CTTTTT 1 -- int10--------
    rs769184141,2
    C--3515955(+) ATGCCA/TGCAGT 1 -- int10--------
    rs359492591,2
    C--3516154(+) GGCTG-/GAGAGTG 1 -- int10--------
    rs105490831,2
    C--3516155(+) TGGAGAG/-TGCCC 1 -- int11Minor allele frequency- -:0.50NA 2
    rs725987841,2
    C--3516157(+) CTGGR-/A/AG  
            
    GTGCC
    1 -- int10--------
    rs1901077891,2
    --3516170(+) GACTCA/CTGGGC 1 -- int10--------
    rs580593361,2
    C,F--3516187(+) TGGGTC/ATCCAG 1 -- int11Minor allele frequency- A:0.50WA 2
    rs1859000151,2
    --3516225(+) ACGAGA/GCAGTG 1 -- int10--------
    rs17944411,2
    C,F,A,H--3516369(+) AGACAA/GCAGCG 1 -- int116Minor allele frequency- G:0.27EA NA WA CSA 481
    rs3714256991,2
    C--3516431(+) CATCTC/TTCCTG 1 -- int10--------
    rs22850881,2
    C,F,A,H--3516448(+) AACTGT/CGGCCT 1 -- int111Minor allele frequency- C:0.41EA NA WA CSA EU 2501
    rs178482861,2
    C--3516457(-) GGACCA/GGGGAG 1 -- int10--------
    rs2005635591,2
    --3516470(+) GAACCC/TGTGCG 1 -- int10--------
    rs1421631671,2
    C--3516476(+) GTGCGC/TACCGT 1 -- int10--------
    rs1405655431,2
    C,F--3516480(+) GCACCA/C/GTGTAG 3 T R M mis12NA EU 5703
    rs1437143101,2
    C,F--3516501(+) TGGTCC/TGCCCC 2 Q R mis11Minor allele frequency- T:0.00NA 4520
    rs2001595691,2
    C--3516511(+) CTCCAC/GCAGGG 2 L V mis10--------
    rs1480772681,2
    C,F--3516517(+) CAGGGC/TGTGCT 2 T A mis11Minor allele frequency- T:0.00NA 4530
    rs1409471051,2
    C--3516528(+) TCTCGC/TGGCTG 2 H R mis11Minor allele frequency- T:0.00NA 4528
    rs2004245261,2
    C,F--3516529(+) CTCGCG/AGCTGC 2 /R /C mis11Minor allele frequency- A:0.00EU 1317
    rs2014966521,2
    --3516539(+) CGGCTC/TACACG 2 V syn10--------
    rs359196941,2
    C,F--3516551(-) GGCGAC/TGGCGA 2 D syn12Minor allele frequency- T:0.01NA 4624
    rs18004931,2,4
    C,F--3516559(-) AGAGCG/ATGGGC 2 /M /V mis14Minor allele frequency- A:0.01NA MN EU 6057
    rs115495121,2
    C,F,H--3516560(-) GAGAGC/TGTGGG 2 S syn19Minor allele frequency- T:0.03NS NA EU 6671
    rs2005327991,2
    C--3516587(+) TCGTGA/C/TGCAAT 3 A syn10--------
    rs2013844511,2
    C--3516588(+) CGTGCG/ACAATC 2 /A /V mis11Minor allele frequency- A:0.00EU 1323
    rs1453038521,2
    C--3516658(+) CTCCTA/GGAACA 1 -- int10--------
    rs25159671,2
    C,F,H--3516689(+) TCCCTC/TCCCGT 1 -- int1 trp313Minor allele frequency- T:0.01NA WA CSA EA 380
    rs1476498961,2
    C--3516703(+) CGCCAC/TGCCAT 1 -- int10--------
    rs17944421,2
    C,F,A,H--3516742(+) GCCAAG/AGGACG 1 -- int114Minor allele frequency- A:0.24NA WA CSA EA 381
    rs1415204651,2
    --3516777(+) CCTTGC/TGGTGA 1 -- int10--------
    rs17415501,2
    C,F--3517049(-) AGGGCA/GCCTAC 1 -- int110Minor allele frequency- G:0.42EA NA WA CSA 1858
    rs1504148671,2
    --3517132(+) CCTGCA/GGCCAG 1 -- int10--------
    rs769114131,2
    C,F--3517175(+) GACCCC/GTTTCT 1 -- int11Minor allele frequency- G:0.13WA 118
    rs17944431,2
    C,F--3517339(+) CCCCGC/ATGGAC 1 -- int113Minor allele frequency- A:0.25NA WA CSA EA 376
    rs737939801,2
    C,F--3517361(+) CACAGC/TCCTGC 1 -- int11Minor allele frequency- T:0.50WA 2
    rs131292121,2
    C,F--3517389(+) GATGAA/GTTCTC 1 -- int17Minor allele frequency- G:0.14NA WA 248
    rs1491673371,2
    C--3517454(+) GTGGTA/CTCCTT 1 -- int10--------
    rs31351651,2
    C,F,A--3517483(+) CTCAGG/CAAGTG 1 -- int17Minor allele frequency- C:0.32NA CSA WA EA 366
    rs744639011,2
    C,F--3517485(+) CAGGAA/CGTGGT 1 -- int11Minor allele frequency- C:0.02EA 120
    rs2016742211,2
    C--3517509(+) GATCCC/TGGTAG 1 -- int10--------
    rs1840201831,2
    --3517570(+) GACCAC/TCCACA 1 -- int10--------
    rs1389746911,2
    --3517672(+) GTTCCC/TACGCA 1 -- int10--------
    rs1157634141,2
    F--3517679(+)