Aliases for LRPAP1 Gene
Aliases for LRPAP1 Gene
- LDL Receptor Related Protein Associated Protein 1 2 3 5
- Low Density Lipoprotein-Related Protein-Associated Protein 1 (Alpha-2-Macroglobulin Receptor-Associated Protein 1) 2 3
- Low Density Lipoprotein Receptor-Related Protein Associated Protein 1 2 3
- Alpha-2-MRAP 3 4
- A2MRAP 3 4
- RAP 3 4
- Low Density Lipoprotein Receptor-Related Protein-Associated Protein 1 4
External Ids for LRPAP1 Gene
- HGNC: 6701
- Entrez Gene: 4043
- Ensembl: ENSG00000163956
- OMIM: 104225
- UniProtKB: P30533
Previous HGNC Symbols for LRPAP1 Gene
- A2MRAP
Previous GeneCards Identifiers for LRPAP1 Gene
- GC04M003517
- GC04M003420
- GC04M003545
- GC04M003551
Summaries for LRPAP1 Gene
-
This gene encodes a protein that interacts with the low density lipoprotein (LDL) receptor-related protein and facilitates its proper folding and localization by preventing the binding of ligands. Mutations in this gene have been identified in individuals with myopia 23. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]
GeneCards Summary for LRPAP1 Gene
LRPAP1 (LDL Receptor Related Protein Associated Protein 1) is a Protein Coding gene. Diseases associated with LRPAP1 include myopia 23, autosomal recessive and rare isolated myopia. Among its related pathways are Lissencephaly gene (LIS1) in neuronal migration and development and Reelin signaling pathway. GO annotations related to this gene include heparin binding and low-density lipoprotein particle receptor binding.
UniProtKB/Swiss-Prot for LRPAP1 Gene
-
Interacts with LRP1/alpha-2-macroglobulin receptor and glycoprotein 330.
No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for LRPAP1 Gene
Genomics for LRPAP1 Gene
Regulatory Elements for LRPAP1 Gene
Enhancers for LRPAP1 Gene
| GeneHancer Identifier | Score | Enhancer Sources | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Other Gene Targets for Enhancer |
|---|
Enhancers around LRPAP1 on UCSC Golden Path with GeneCards custom track
Promoters for LRPAP1 Gene
| Ensembl Regulatory Elements (ENSRs) | TSS Distance (bp) | Size (bp) | Binding Sites for Transcription Factors within promoters |
|---|
ENSRs around LRPAP1 on UCSC Golden Path with GeneCards custom track
- Transcription factor binding sites by QIAGEN in the LRPAP1 gene promoter:
Regulatory Element Products
Genomic Location for LRPAP1 Gene
- Chromosome:
- 4
- Start:
- 3,503,597 bp from pter
- End:
- 3,532,559 bp from pter
- Size:
- 28,963 bases
- Orientation:
- Minus strand
Genomic View for LRPAP1 Gene
Genes around LRPAP1 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 4p16.3 by Ensembl
- 4p16.3 by Entrez Gene
- 4p16.3 by HGNC
LRPAP1 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for LRPAP1 Gene
Proteins for LRPAP1 Gene
-
Protein details for LRPAP1 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P30533-AMRP_HUMAN
- Recommended name:
- Alpha-2-macroglobulin receptor-associated protein
- Protein Accession:
- P30533
- D3DVR9
- Q2M310
- Q53HQ3
- Q53HS6
Protein attributes for LRPAP1 Gene
- Size:
- 357 amino acids
- Molecular mass:
- 41466 Da
- Quaternary structure:
-
- Present on cell surface forming a complex with the alpha-2-macroglobulin receptor heavy and light chains. Binds LRP1B; binding is followed by internalization and degradation.
Protein Expression for LRPAP1 Gene
Post-translational modifications for LRPAP1 Gene
- N-glycosylated.
- Glycosylation at Thr 134, Asn 268, Thr 337, and Ser 346
- Modification sites at PhosphoSitePlus
Other Protein References for LRPAP1 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
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-
Cloud-Clone Corp. Antibodies for LRPAP1
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- antibodies-online Antibodies for LRPAP1: See all 102
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-
Santa Cruz Biotechnology (SCBT) Antibodies for LRPAP1
Protein Products
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-
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-
Cloud-Clone Corp. Proteins for LRPAP1
- antibodies-online Proteins for LRPAP1: See all 23
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Assay Products
- antibodies-online Kits for LRPAP1: See all 7
No data available for DME Specific Peptides for LRPAP1 Gene
Domains & Families for LRPAP1 Gene
Protein Domains for LRPAP1 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for LRPAP1 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
P30533- Family:
-
- Belongs to the alpha-2-MRAP family.
No data available for Gene Families for LRPAP1 Gene
Function for LRPAP1 Gene
Molecular function for LRPAP1 Gene
- GENATLAS Biochemistry:
- low density lipoprotein receptor related protein,associated protein 1
- UniProtKB/Swiss-Prot Function:
- Interacts with LRP1/alpha-2-macroglobulin receptor and glycoprotein 330.
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0051082 | unfolded protein binding | TAS | 8654360 |
| GO:0070326 | very-low-density lipoprotein particle receptor binding | IPI | 8083232 |
Phenotypes for LRPAP1 Gene
- MGI mutant phenotypes for LRPAP1:
- inferred from 2 alleles
- GenomeRNAi human phenotypes for LRPAP1:
Animal Model Products
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-
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CRISPR Products
-
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-
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miRNA for LRPAP1 Gene
- miRTarBase miRNAs that target LRPAP1
-
- hsa-mir-26b-5p (MIRT029205)
- hsa-mir-615-3p (MIRT040189)
- hsa-mir-6790-5p (MIRT526350)
- hsa-mir-4658 (MIRT526351)
- hsa-mir-197-3p (MIRT526352)
- hsa-mir-3659 (MIRT526353)
- hsa-mir-574-5p (MIRT526354)
- hsa-mir-138-2-3p (MIRT526355)
- hsa-mir-3691-3p (MIRT526356)
- hsa-mir-3174 (MIRT526357)
- hsa-mir-140-3p (MIRT526358)
- hsa-mir-6501-3p (MIRT562957)
- hsa-mir-95-5p (MIRT562958)
- hsa-mir-5590-3p (MIRT562959)
- hsa-mir-142-5p (MIRT562960)
- hsa-mir-519c-3p (MIRT562961)
- hsa-mir-519b-3p (MIRT562962)
- hsa-mir-519a-3p (MIRT562963)
- hsa-mir-4796-3p (MIRT562964)
- hsa-mir-93-5p (MIRT562965)
- hsa-mir-526b-3p (MIRT562966)
- hsa-mir-519d-3p (MIRT562967)
- hsa-mir-20b-5p (MIRT562968)
- hsa-mir-20a-5p (MIRT562969)
- hsa-mir-17-5p (MIRT562970)
- hsa-mir-106b-5p (MIRT562971)
- hsa-mir-106a-5p (MIRT562972)
- hsa-mir-548ah-5p (MIRT562973)
- hsa-mir-4668-3p (MIRT562974)
- hsa-mir-3609 (MIRT562975)
- hsa-mir-7977 (MIRT631102)
- hsa-mir-6721-5p (MIRT631103)
- hsa-mir-383-3p (MIRT631104)
- hsa-mir-6848-3p (MIRT669914)
- hsa-mir-6843-3p (MIRT669915)
- hsa-mir-3187-3p (MIRT669916)
- hsa-mir-4435 (MIRT669917)
- hsa-mir-588 (MIRT669918)
- hsa-mir-4701-5p (MIRT669919)
- hsa-mir-548s (MIRT669920)
- hsa-mir-378a-5p (MIRT669921)
- hsa-mir-6131 (MIRT669922)
- hsa-mir-4755-3p (MIRT669923)
- hsa-mir-4454 (MIRT669924)
- hsa-mir-6821-3p (MIRT669925)
- hsa-mir-6790-3p (MIRT669926)
- hsa-mir-3663-5p (MIRT669927)
- hsa-mir-3653-5p (MIRT669928)
- hsa-mir-372-5p (MIRT669929)
- hsa-mir-371a-5p (MIRT669930)
- hsa-mir-4716-5p (MIRT669931)
- hsa-mir-6767-3p (MIRT669932)
- hsa-mir-4781-3p (MIRT669933)
- hsa-mir-767-5p (MIRT708689)
- hsa-mir-342-3p (MIRT708690)
- hsa-mir-1228-3p (MIRT708691)
- hsa-mir-7153-3p (MIRT708692)
- hsa-mir-649 (MIRT708693)
miRNA Products
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Flow Cytometry Products
No data available for Enzyme Numbers (IUBMB) , Transcription Factor Targets and HOMER Transcription for LRPAP1 Gene
Localization for LRPAP1 Gene
Subcellular locations from UniProtKB/Swiss-Prot for LRPAP1 Gene
- Endoplasmic reticulum. Cytoplasm. Cell surface. Note=Intracellular and associated with cell surface receptors. Found in the endoplasmic reticulum.
| Compartment | Confidence |
|---|---|
| endoplasmic reticulum | 5 |
| extracellular | 5 |
| plasma membrane | 5 |
| cytoskeleton | 2 |
| cytosol | 1 |
| lysosome | 1 |
| nucleus | 1 |
| vacuole | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005576 | extracellular region | IDA | 8083232 |
| GO:0005783 | endoplasmic reticulum | IEA,IDA | -- |
| GO:0016021 | integral component of membrane | TAS | 1712782 |
| GO:0048237 | rough endoplasmic reticulum lumen | IEA | -- |
Pathways & Interactions for LRPAP1 Gene
More details on SuperPathways for LRPAP1| Superpath | Contained pathways | |
|---|---|---|
| 1 | Lissencephaly gene (LIS1) in neuronal migration and development | |
| 2 | Reelin signaling pathway | |
| 3 | Signaling events mediated by the Hedgehog family |
Pathways by source for LRPAP1 Gene
3 BioSystems pathways for LRPAP1 Gene
Interacting Proteins for LRPAP1 Gene
Selected Interacting proteins:
P30533-AMRP_HUMAN
ENSP00000421922
for LRPAP1 Gene via
MINT
STRING
UniProtKB
I2D
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0010916 | negative regulation of very-low-density lipoprotein particle clearance | IDA | 8083232 |
| GO:1900222 | negative regulation of beta-amyloid clearance | IGI | 19098903 |
No data available for SIGNOR curated interactions for LRPAP1 Gene
Transcripts for LRPAP1 Gene
mRNA/cDNA for LRPAP1 Gene
- (1) REFSEQ mRNAs :
- (17) Additional mRNA sequences :
- (696) Selected AceView cDNA sequences:
- (4) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for LRPAP1 Gene
CRISPR Products
-
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-
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miRNA Products
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Flow Cytometry Products
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3a | · | 3b | ^ | 4a | · | 4b | · | 4c | ^ | 5 | ^ | 6a | · | 6b | ^ | 7a | · | 7b | · | 7c | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | - | ||||||||||||||||||||||||||||||
| SP2: | - | - | - | - | - | - | - | - | |||||||||||||||||||||||||||
| SP3: | - | - | - | ||||||||||||||||||||||||||||||||
| SP4: | - | - | - | - | - | ||||||||||||||||||||||||||||||
| SP5: | - | - | |||||||||||||||||||||||||||||||||
| SP6: | - | - | |||||||||||||||||||||||||||||||||
| SP7: | - | - | |||||||||||||||||||||||||||||||||
| SP8: |
Expression for LRPAP1 Gene
mRNA differential expression in normal tissues according to GTEx for LRPAP1 Gene
This gene is overexpressed in Whole Blood (x4.4).
This gene is overexpressed in Testis (15.8) and Bone marrow stromal cell (6.2).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for LRPAP1 Gene
SOURCE GeneReport for Unigene cluster for LRPAP1 Gene Hs.40966
Primer Products
-
OriGene qPCR primer pairs for LRPAP1
-
OriGene qPCR primer pairs and template standards for LRPAP1
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for LRPAP1 Gene
Orthologs for LRPAP1 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| cow (Bos Taurus) |
Mammalia | LRPAP1 35 |
|
||
| LRPAP1 36 |
|
OneToOne | |||
| dog (Canis familiaris) |
Mammalia | LRPAP1 35 |
|
||
| LRPAP1 36 |
|
OneToOne | |||
| mouse (Mus musculus) |
Mammalia | Lrpap1 35 |
|
||
| Lrpap1 16 |
|
||||
| Lrpap1 36 |
|
OneToOne | |||
| chimpanzee (Pan troglodytes) |
Mammalia | LRPAP1 35 |
|
||
| LRPAP1 36 |
|
OneToOne | |||
| rat (Rattus norvegicus) |
Mammalia | Lrpap1 35 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | LRPAP1 36 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | LRPAP1 35 |
|
||
| LRPAP1 36 |
|
OneToOne | |||
| lizard (Anolis carolinensis) |
Reptilia | LRPAP1 36 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | lrpap1 35 |
|
||
| Str.1732 35 |
|
||||
| African clawed frog (Xenopus laevis) |
Amphibia | LOC398643 35 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | lrpap1 35 |
|
||
| lrpap1 36 |
|
OneToOne | |||
| fruit fly (Drosophila melanogaster) |
Insecta | CG8507 37 |
|
|
|
| CG8507 35 |
|
||||
| CG8507 36 |
|
OneToOne | |||
| African malaria mosquito (Anopheles gambiae) |
Insecta | AgaP_AGAP003521 35 |
|
||
| sea squirt (Ciona savignyi) |
Ascidiacea | CSA.9235 36 |
|
OneToOne |
- Species with no ortholog for LRPAP1:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- platypus (Ornithorhynchus anatinus)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Paralogs for LRPAP1 Gene
No data available for Paralogs for LRPAP1 Gene
Variants for LRPAP1 Gene
| SNP ID | Clin | Chr 04 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1800493 | - | 3,514,832(-) | AGAGC(A/G)TGGGC | nc-transcript-variant, reference, missense | |
| rs2228158 | - | 3,524,915(-) | ACGCA(A/G/T)CCTCA | nc-transcript-variant, reference, missense | |
| rs3182 | -- | 3,508,871(-) | GCGCT(C/T)GCTAA | nc-transcript-variant, utr-variant-3-prime | |
| rs3183 | -- | 3,508,888(-) | ACTGG(C/T)GAGGT | nc-transcript-variant, utr-variant-3-prime | |
| rs3184 | -- | 3,508,787(-) | CAGGC(A/G)GAAGA | nc-transcript-variant, utr-variant-3-prime |
Residual Variation Intolerance Score:
83.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
4.66;
65.76% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for LRPAP1 Gene
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for LRPAP1 Gene
Disorders for LRPAP1 Gene
(8) MalaCards diseases for LRPAP1 Gene - From: OMIM, ClinVar, Orphanet, DISEASES, Novoseek, and GeneCards
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| myopia 23, autosomal recessive |
|
|
| rare isolated myopia |
|
|
| myopia |
|
|
| babesiosis |
|
|
| refractive error |
|
|
Search LRPAP1 in MalaCards
View complete list of genes associated with diseases
UniProtKB/Swiss-Prot
AMRP_HUMAN- Myopia 23, autosomal recessive (MYP23) [MIM:615431]: A refractive error of the eye, in which parallel rays from a distant object come to focus in front of the retina, vision being better for near objects than for far. {ECO:0000269 PubMed:23830514}. Note=The disease is caused by mutations affecting the gene represented in this entry.
- Note=In complex with the alpha-2-MR or gp330, it may have some role in the pathogenesis of membrane glomerular nephritis.
Relevant External Links for LRPAP1
No data available for Genatlas for LRPAP1 Gene
Publications for LRPAP1 Gene
- Analysis of the human LRPAP1 gene coding for the lipoprotein receptor-associated protein: identification of 22 polymorphisms and one mutation. (PMID: 9782079) Van Leuven F. … Nelissen B. (Genomics 1998) 3 4 23 48 67
- Low-density lipoprotein receptor-related protein-associated protein (LRPAP1) gene IVS5 insertion/deletion polymorphism is not a risk factor for gallstone disease in a Polish population. (PMID: 17913606) Juzyszyn Z. … DroA_dzik M. (Dig Liver Dis 2008) 3 23
- LRP-associated protein gene (LRPAP1) and susceptibility to degenerative dementia. (PMID: 18721259) Pandey P. … Mittal B. (Genes Brain Behav. 2008) 3 23
- Interaction of lipoprotein lipase and receptor-associated protein. (PMID: 16517593) Page S. … Bensadoun A. (J. Biol. Chem. 2006) 3 23
- Alpha2-macroglobulin, lipoprotein receptor-related protein and lipoprotein receptor-associated protein and the genetic risk for developing Alzheimer's disease. (PMID: 16650578) Depboylu C. … Dodel R.C. (Neurosci. Lett. 2006) 3 23
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- Search ViGene Biosciences for LRPAP1
- Santa Cruz Biotechnology (SCBT) Antibodies for LRPAP1
- Search Santa Cruz Biotechnology (SCBT) for LRPAP1 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for LRPAP1
Sources for LRPAP1 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) I2D
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) UniGene
- (28) AceView
- (29) RNAdb
- (30) ASD
- (31) ECgene
- (32) GeneAnnot
- (33) SAGE
- (34) SOURCE
- (35) HomoloGene
- (36) PanEnsembl
- (37) euGenes
- (38) SGD
- (39) FlyBase
- (40) WormBase
- (41) Pseudogene
- (42) DGV
- (43) dbSNP
- (44) HapMap
- (45) GenAtlas
- (46) GeneTests
- (47) HGMD
- (48) GAD
- (49) LSDB
- (50) BGMUT
- (51) HuGE
- (52) eBioscience
- (53) Atlas
- (54) Cell Signaling Technology
- (55) GenBank
- (56) H-invDB
- (57) HORDE
- (58) HUGE
- (59) IMGT
- (60) Leiden
- (61) MILLIPORE
- (62) miRBase
- (63) DME
- (64) Nature
- (65) NCBI
- (66) OriGene
- (67) PubMed
- (68) R&D Systems
- (69) Salk
- (70) TGDB
- (71) Tufts
- (72) YEDA
- (73) CROW21
- (74) Tocris
- (75) Abcam
- (76) Novus
- (77) ProSpec
- (78) Sino Biological
- (79) GenScript
- (80) Qiagen
- (81) Cloud-Clone Corp.
- (82) Enzo Life Sciences
- (83) OCA
- (84) Proteopedia
- (85) MOPED
- (86) SPIRE
- (87) neXtProt
- (88) Reactome
- (89) GeneGo (Thomson Reuters)
- (90) fRNAdb
- (91) DISEASES
- (92) SIMAP
- (93) GenomeRNAi
- (94) LifeMap
- (95) miRTarBase
- (96) MalaCards
- (97) Invitrogen
- (98) BitterDB
- (99) Vector BioLabs
- (100) ESI-BIO
- (101) RefSeq
- (102) BioSystems
- (103) MaxQB
- (104) IUPHAR
- (105) BioGPS
- (106) Illumina
- (107) COMPARTMENTS
- (108) HOMER
- (109) PaxDb
- (110) ApexBio
- (111) Addgene
- (112) Advanced Cell Diagnostics
- (113) antibodies-online
- (114) CYP
- (115) NONCODE
- (116) SwitchGear Genomics
- (117) TreeFam
- (118) PathCards
- (119) GeneReviews
- (120) GeneTex
- (121) Taconic Biosciences
- (122) GTEx
- (123) ProteomicsDB
- (124) SCBT
- (125) DGIdb
- (126) ClinicalTrials
- (127) FDA Approved Drugs
- (128) RVIS
- (129) SIGNOR
- (130) diseasecard
- (131) NIH Rare Diseases
- (132) Orphanet
- (133) UMLS
- (134) GTR
- (135) Disease Ontology
- (136) Genetics Home Reference
- (137) MeSH
- (138) MedlinePlus
- (139) CDC
- (140) NINDS
- (141) NCBI Bookshelf
- (142) ClinVar
- (143) Gene Damage Index
- (144) ViGene Biosciences
- (145) HPO
- (146) UDN
- (147) VISTA
- (148) FANTOM5
- (149) ENCODE
- (150) ProSci
- (151) Horizon