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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

LRP10 Gene

protein-coding   GIFtS: 55
GCID: GC14P023340

Low Density Lipoprotein Receptor-Related Protein 10

  Search for LRP10
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Low Density Lipoprotein Receptor-Related Protein 101 2
LRP-102 3
LRP92 5
MST0872
Low-Density Lipoprotein Receptor-Related Protein 102

External Ids:    HGNC: 145531   Entrez Gene: 260202   Ensembl: ENSG000001973247   OMIM: 6099215   UniProtKB: Q7Z4F13   

Export aliases for LRP10 gene to outside databases

Previous GC identifers: GC14P020717 GC14P017128 GC14P021331 GC14P022410 GC14P003458


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for LRP10 Gene: 
LRP10 (low density lipoprotein receptor-related protein 10) is a protein-coding gene. Among its related super-pathways are Visual phototransduction and Signaling by GPCR. GO annotations related to this gene include low-density lipoprotein receptor activity. An important paralog of this gene is LRP12.

UniProtKB/Swiss-Prot: LRP10_HUMAN, Q7Z4F1
Function: Probable receptor, which is involved in the internalization of lipophilic molecules and/or signal
transduction. May be involved in the uptake of lipoprotein APOE in liver (By similarity)

Gene Wiki entry for LRP10 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000014.8  NT_026437.12  NC_018925.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the LRP10 gene promoter:
         NF-1   NF-1/L   AML1a   HTF   Hand1   ZID   Pax-4a   E47   ATF   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidLRP10 promoter sequence
   Search SABiosciences Chromatin IP Primers for LRP10

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat LRP10


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 14q11.2   Ensembl cytogenetic band:  14q11.2   HGNC cytogenetic band: 14q11.2

LRP10 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
LRP10 gene location

GeneLoc information about chromosome 14         GeneLoc Exon Structure

GeneLoc location for GC14P023340:  view genomic region     (about GC identifiers)

Start:
23,340,822 bp from pter      End:
23,350,789 bp from pter
Size:
9,968 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: LRP10_HUMAN, Q7Z4F1 (See protein sequence)
Recommended Name: Low-density lipoprotein receptor-related protein 10 precursor  
Size: 713 amino acids; 76193 Da
Subcellular location: Membrane; Single-pass type I membrane protein (Potential). Membrane, coated pit (By
similarity)
Sequence caution: Sequence=AAD20037.1; Type=Erroneous initiation; Sequence=AAG17980.1; Type=Frameshift;
Positions=370, 700; Sequence=AAQ13610.1; Type=Frameshift; Positions=312, 337, 496, 502, 512; Sequence=CAD39174.2;
Type=Miscellaneous discrepancy; Note=Chimera;
Secondary accessions: A8K4R5 D3DS31 O95882 Q14CK7 Q86T02 Q8NCZ4 Q9HC42 Q9UG33
Alternative splicing: 2 isoforms:  Q7Z4F1-1   Q7Z4F1-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for LRP10: NX_Q7Z4F1

Explore proteomics data for LRP10 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q7Z4F1

  • LRP10 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    LRP10 Protein Expression
    REFSEQ proteins: NP_054764.2  
    ENSEMBL proteins: 
     ENSP00000352601   ENSP00000447559   ENSP00000447977  
    Reactome Protein details: Q7Z4F1
    Human Recombinant Protein Products for LRP10: 
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    Novus Biologicals LRP10 Protein
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    Sino Biological Recombinant Protein for LRP10
    Sino Biological Cell Lysate for LRP10 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for LRP10 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005905coated pit IEA--
    GO:0016021integral to membrane IEA--

    LRP10 for ontologies           About GeneDecksing



    LRP10 Antibody Products: 
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    Cloud-Clone Corp. CLIAs for LRP10


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    LDLR: Low density lipoprotein receptors

    3 InterPro protein domains:
     IPR000859 CUB_dom
     IPR002172 LDrepeatLR_classA_rpt
     IPR023415 LDLR_class-A_CS

    Graphical View of Domain Structure for InterPro Entry Q7Z4F1

    ProtoNet protein and cluster: Q7Z4F1

    2 Blocks protein domains:
    IPB000859 CUB domain
    IPB002172 Low density lipoprotein-receptor


    UniProtKB/Swiss-Prot: LRP10_HUMAN, Q7Z4F1
    Similarity: Belongs to the LDLR family
    Similarity: Contains 2 CUB domains
    Similarity: Contains 4 LDL-receptor class A domains


    LRP10 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: LRP10_HUMAN, Q7Z4F1
    Function: Probable receptor, which is involved in the internalization of lipophilic molecules and/or signal
    transduction. May be involved in the uptake of lipoprotein APOE in liver (By similarity)

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005041low-density lipoprotein receptor activity ----
    GO:0005515protein binding ----
         
    LRP10 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for LRP10:
     Decreased viability of wild-ty 

         1 MGI phenotypic allele for Lrp10 (no phenotypes)

    LRP10 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Lrp10tm1Lex for LRP10

       inGenious Targeting Laboratory - Custom generated mouse model solutions for LRP10 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for LRP10

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for LRP10 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for LRP10 

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    6 QIAGEN miScript miRNA Assays for microRNAs that regulate LRP10:
    hsa-miR-31 hsa-miR-145* hsa-miR-182 hsa-miR-122 hsa-miR-1271 hsa-miR-96
    SwitchGear 3'UTR luciferase reporter plasmidLRP10 3' UTR sequence
    Inhib. RNA
    Products:
        
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for LRP10


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for LRP10 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Visual phototransduction
    Visual phototransduction0.48
    Diseases associated with visual transduction0.47
    Retinoid metabolism and transport0.48
    2Signaling by GPCR
    Signal Transduction0.55
    3Disease
    Disease

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways



    5        Reactome Pathways for LRP10
        Diseases associated with visual transduction
    Retinoid metabolism and transport
    Signal Transduction
    Visual phototransduction
    Disease



    LRP10 for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for LRP10

    STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

    2 Interacting proteins for LRP10 (Q7Z4F13 ENSP000003526014) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    HTRA1Q927433, ENSP000003579804I2D: score=1 STRING: ENSP00000357980
    DFNB31ENSP000003546234STRING: ENSP00000354623
    About this table

    Gene Ontology (GO): 4 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006629lipid metabolic process ----
    GO:0006869lipid transport ----
    GO:0006897endocytosis IEA--
    GO:0048839inner ear development ----

    LRP10 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for LRP10

    Search CenterWatch for drugs/clinical trials and news about LRP10

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for LRP10 gene: 
    NM_014045.3  

    Unigene Cluster for LRP10:

    Low density lipoprotein receptor-related protein 10
    Hs.525232  [show with all ESTs]
    Unigene Representative Sequence: NM_014045
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000359591(uc001whd.3 uc001whe.3) ENST00000546834 ENST00000553002
    ENST00000551466 ENST00000470660
    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat LRP10
    6 QIAGEN miScript miRNA Assays for microRNAs that regulate LRP10:
    hsa-miR-31 hsa-miR-145* hsa-miR-182 hsa-miR-122 hsa-miR-1271 hsa-miR-96
    SwitchGear 3'UTR luciferase reporter plasmidLRP10 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for LRP10
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat LRP10
    Clone
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat LRP10
    Sirion Biotech Customized lentivirus for stable overexpression of LRP10 
                         Customized lentivirus expression plasmids for stable overexpression of LRP10 
    Primer
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    OriGene qSTAR qPCR primer pairs in human, mouse for LRP10
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat LRP10
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat LRP10

    Additional mRNA sequence: 

    AF131760.1 AF172816.1 AF177336.1 AK025898.1 AK291030.1 AL080164.1 AL110149.1 AL834518.1 
    AY358399.1 BC000424.2 BC018816.2 BC064901.1 BC080648.1 BC088378.1 BC113714.1 BC113716.1 
    BX161500.1 CR457151.1 

    24/29 DOTS entries (see all 29):

    DT.75182728  DT.91896023  DT.434472  DT.95293751  DT.120760280  DT.102836151  DT.100886211  DT.102836146 
    DT.102836150  DT.102836153  DT.120760336  DT.100693988  DT.102836147  DT.102836154  DT.92463603  DT.95254061 
    DT.100647646  DT.100675732  DT.100677074  DT.100768719  DT.100886209  DT.100886218  DT.102836157  DT.120760334 

    24/668 AceView cDNA sequences (see all 668):

    CF125491 BX371282 BQ278763 BQ690711 CA426707 BU679121 BM695076 T08687 
    BF114903 AI393983 BE889654 AI225064 BU633696 CA313273 BM313674 CB528999 
    AI472418 AI261404 AI912329 BC000424 BE905311 BQ686475 AI720472 AI349335 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for LRP10    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3a · 3b ^ 4a · 4b ^ 5a · 5b · 5c · 5d ^ 6 ^ 7 ^ 8a · 8b · 8c ^ 9
    SP1:                    -                       -                                                         
    SP2:                    -                                                                                 
    SP3:                                            -                 -     -                                 
    SP4:                                                                                      -     -         
    SP5:                                            -                                                         


    ECgene alternative splicing isoforms for LRP10

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    LRP10 expression in normal human tissues (normalized intensities)      LRP10 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GCCAGACACC
    LRP10 Expression
    About this image


    LRP10 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/5 selected tissues (see all 5) fully expand
     
     Brain (Nervous System)    fully expand to see all 15 entries
             Thalamus
             Olfactory Bulb   
     
     Spinal Cord (Nervous System)
             Dorsal Horn   
     
     Blood (Hematopoietic System)
             neutrophils   
     
     Neural Tube (Nervous System)
             Metencephalon
     
     Amnion (Extraembryonic Tissues)
             amniotic fluid   

    See LRP10 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for LRP10

    SOURCE GeneReport for Unigene cluster: Hs.525232

    UniProtKB/Swiss-Prot: LRP10_HUMAN, Q7Z4F1
    Tissue specificity: Expressed in blood leukocyte, lung, placenta, small intestine, liver, kidney, spleen, thymus,
    colon, skeletal muscle and heart

        SABiosciences Expression via Pathway-Focused PCR Array including LRP10: 
              Lipoprotein Signaling & Cholesterol Metabolism in human mouse rat

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for LRP10

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for LRP10 gene from 6/13 species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Lrp101 , 5 low-density lipoprotein receptor-related protein 1 more1, 5 85.93(n)1
    88.1(a)1
      14 (27.80 cM)5
    651071  NM_022993.31  NP_075369.21 
     544641475 
    lizard
    (Anolis carolinensis)
    Reptilia LRP106
    low density lipoprotein receptor-related protein 1...
    54(a)
    1 ↔ 1
    GL343879.1(1612-11940)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.58302 Xenopus laevis transcribed sequence with weak similarity more 73.64(n)    BJ069090.1 
    zebrafish
    (Danio rerio)
    Actinopterygii LOC5603611 low-density lipoprotein receptor-related protein 1 more 50.8(n)
    44.89(a)
      560361  XM_683767.5  XP_688859.4 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG67396
    --
    9(a)
    1 → many
    2L(7608390-7616528)
    worm
    (Caenorhabditis elegans)
    Secernentea lrx-16
    F09B12.56
    (see all 3)
    Protein F09B12.5
    (see all 3)
    20(a)
    17(a)
    (see all 3)
    many ↔ many
    many ↔ many
    (see all 3)
    V(12252647-12255394)
    X(15084749-15088135)


    ENSEMBL Gene Tree for LRP10 (if available)
    TreeFam Gene Tree for LRP10 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for LRP10 gene
    LRP122  LRP22  LRP32  LDLRAD32  
    3 SIMAP similar genes for LRP10 using alignment to 5 protein entries:     LRP10_HUMAN (see all proteins):
    LRP12    VLDLR    LRP3

    LRP10 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/220 SNPs in LRP10 are shown (see all 220)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 14 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1999589191,2
    --23338995(+) AAAAC-/AAAAAC 1 -- us2k10--------
    rs116221841,2
    C,F,H--23339000(+) caaaaC/AaaaaA 1 -- us2k16Minor allele frequency- A:0.17WA NA CSA EA 368
    rs2013396621,2
    --23339000(+) CAAAA-/CAAAAA 1 -- us2k10--------
    rs1897156851,2
    --23339124(+) TCACAC/TTTGTT 1 -- us2k10--------
    rs1140777141,2
    F--23339256(+) CGGCGC/TGCACC 1 -- us2k11Minor allele frequency- T:0.03WA 118
    rs1824214731,2
    --23339279(+) TACTTC/GGGGGG 1 -- us2k10--------
    rs1878121671,2
    --23339326(+) AACCCG/TGGAGG 1 -- us2k10--------
    rs1926955131,2
    --23339501(+) CTCACA/GCCTGT 1 -- us2k10--------
    rs1402398211,2
    --23339634(+) GCAGCA/GGGCGC 1 -- us2k10--------
    rs1851383631,2
    --23339638(+) CGGGCA/GCCTGT 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for LRP10 (23340822 - 23350789 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for LRP10:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv901490CNV Loss21882294
    nsv1214CNV Loss18451855

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    LRP10 for disorders           About MalaCards
    OMIM gene information: 609921    OMIM disorders: --


    LRP10 for disorders           About GeneDecksing


    Export disorders for LRP10 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for LRP10 gene, integrated from 9 sources (see all 21):
    (articles sorted by number of sources associating them with LRP10)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. A novel low-density lipoprotein receptor-related protein mediating cellular uptake of apolipoprotein E-enriched beta-VLDL in vitro. (PubMed id 11123907)1, 2, 3 Sugiyama T.... Kitamura T. (2000)
    2. Large-scale cDNA transfection screening for genes related to cancer development and progression. (PubMed id 15498874)1, 2 Wan D....Gu J. (2004)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (2003)
    5. Large-scale concatenation cDNA sequencing. (PubMed id 9110174)1, 2 Yu W.... Gibbs R.A. (1997)
    6. LDLR-related protein 10 (LRP10) regulates amyloid prec ursor protein (APP) trafficking and processing: evidence for a role in Alzheimer 's disease. (PubMed id 22734645)1 Brodeur J....Lavoie C. (2012)
    7. Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
    8. Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PubMed id 20068231)2 Olsen J.V....Mann M. (2010)
    9. The low-density lipoprotein receptor-related protein 10 is a negative regulator of the canonical Wnt/beta-catenin signaling pathway. (PubMed id 20093106)1 Jeong Y.H....Saeki S. (2010)
    10. Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle. (PubMed id 18691976)2 Daub H.... Mann M. (2008)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
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    Aliases
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      Query String
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 26020 HGNC: 14553 AceView: LRP10 Ensembl:ENSG00000197324 euGenes: HUgn26020
    ECgene: LRP10 H-InvDB: LRP10

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for LRP10 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for LRP10 gene:
    Search GeneIP for patents involving LRP10

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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