Aliases for LRIG2 Gene
External Ids for LRIG2 Gene
Previous GeneCards Identifiers for LRIG2 Gene
This gene encodes a transmembrane protein containing leucine-rich repeats and immunoglobulin-like domains. The encoded protein promotes epidermal growth factor signalling, resulting in increased proliferation. Its expression in the cytoplasm of glioma cells is correlated with poor survival. Mutations in this gene can cause urofacial syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015]
GeneCards Summary for LRIG2 Gene
LRIG2 (Leucine-Rich Repeats And Immunoglobulin-Like Domains 2) is a Protein Coding gene. Diseases associated with LRIG2 include lrig2-related urofacial syndrome and urofacial syndrome 2. An important paralog of this gene is LRRTM2.