Aliases for LRIG1 Gene
External Ids for LRIG1 Gene
Previous GeneCards Identifiers for LRIG1 Gene
GeneCards Summary for LRIG1 Gene
LRIG1 (Leucine Rich Repeats And Immunoglobulin Like Domains 1) is a Protein Coding gene. Diseases associated with LRIG1 include Verrucous Carcinoma and Eccrine Porocarcinoma. Among its related pathways are Listeria monocytogenes entry into host cells and Tyrosine Kinases / Adaptors. An important paralog of this gene is LRIG3.
UniProtKB/Swiss-Prot for LRIG1 Gene
Acts as a feedback negative regulator of signaling by receptor tyrosine kinases, through a mechanism that involves enhancement of receptor ubiquitination and accelerated intracellular degradation.