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LRCH2 Gene

protein-coding   GIFtS: 49
GCID: GC0XM114345

Leucine-Rich Repeats And Calponin Homology (CH) Domain Containing...

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Leucine-Rich Repeats And Calponin Homology (CH) Domain Containing 21 2
dA204F4.42
Leucine-Rich Repeat And Calponin Homology Domain-Containing Protein 22
KIAA14953

External Ids:    HGNC: 292921   Entrez Gene: 576312   Ensembl: ENSG000001302247   UniProtKB: Q5VUJ63   

Export aliases for LRCH2 gene to outside databases

Previous GC identifers: GC0XM113110 GC0XM114168 GC0XM114251 GC0XM103930


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for LRCH2 Gene:
This gene encodes a member of the leucine-rich repeat and calponin homology domain-containing protein family.
These family members contain multiple N-terminal leucine-rich repeats, in addition to a C-terminal calponin
homology domain, a type of domain that mediates interactions with actin filaments. These proteins are conserved
across animal species, and studies of a similar Drosophila protein indicate a function as a cytoskeletal
scaffolding protein. Alternative splicing of this gene results in multiple transcript variants. (provided by
RefSeq, Sep 2011)

GeneCards Summary for LRCH2 Gene:
LRCH2 (leucine-rich repeats and calponin homology (CH) domain containing 2) is a protein-coding gene. An important paralog of this gene is LRRC2.




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000023.10  NT_028405.13  NC_018934.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the LRCH2 gene promoter:
         GR   Egr-3   NF-YA   NF-YB   CBF-A   CBF-B   GR-alpha   CP1A   NF-Y   CBF(2)   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidLRCH2 promoter sequence
   Search Chromatin IP Primers for LRCH2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat LRCH2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: Xq23   Ensembl cytogenetic band:  Xq23   HGNC cytogenetic band: Xq24

LRCH2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
LRCH2 gene location

GeneLoc information about chromosome X         GeneLoc Exon Structure

GeneLoc location for GC0XM114345:  view genomic region     (about GC identifiers)

Start:
114,345,179 bp from pter      End:
114,468,635 bp from pter
Size:
123,457 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: LRCH2_HUMAN, Q5VUJ6 (See protein sequence)
Recommended Name: Leucine-rich repeat and calponin homology domain-containing protein 2  
Size: 765 amino acids; 84588 Da
Sequence caution: Sequence=BAA96019.1; Type=Erroneous initiation; Sequence=CAH70721.1; Type=Erroneous gene model
prediction; Sequence=CAI42077.1; Type=Erroneous gene model prediction; Sequence=CAI43033.1; Type=Erroneous gene
model prediction;
Secondary accessions: F5H2T1 Q08AD5 Q9HA88 Q9P233
Alternative splicing: 2 isoforms:  Q5VUJ6-1   Q5VUJ6-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for LRCH2: NX_Q5VUJ6

Explore proteomics data for LRCH2 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See LRCH2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001230892.1  NP_065922.3  

    ENSEMBL proteins: 
     ENSP00000325091   ENSP00000439366  

    LRCH2 Human Recombinant Protein Products:

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    Cloud-Clone Corp. Proteins for LRCH2

     
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    antibodies-online proteins for LRCH2 

     
    Search antibodies-online for peptides for LRCH2

    LRCH2 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
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    antibodies-online antibodies for LRCH2 (14 products) 

    LRCH2 Assay Products:

    Browse Kits and Assays available from EMD Millipore
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    Cloud-Clone Corp. ELISAs for LRCH2
    Cloud-Clone Corp. CLIAs for LRCH2
    Search eBioscience for ELISAs for LRCH2 
    antibodies-online kits for LRCH2 (4 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    3 InterPro protein domains:
     IPR001715 CH-domain
     IPR001611 Leu-rich_rpt
     IPR003591 Leu-rich_rpt_typical-subtyp

    Graphical View of Domain Structure for InterPro Entry Q5VUJ6

    ProtoNet protein and cluster: Q5VUJ6

    2 Blocks protein domains:
    IPB001611 Leucine-rich repeat signature
    IPB001715 Calponin-like actin-binding


    UniProtKB/Swiss-Prot: LRCH2_HUMAN, Q5VUJ6
    Similarity: Contains 1 CH (calponin-homology) domain
    Similarity: Contains 9 LRR (leucine-rich) repeats


    Find genes that share domains with LRCH2           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
         
    Find genes that share ontologies with LRCH2           About GenesLikeMe


    Phenotypes:
         2 GenomeRNAi human phenotypes for LRCH2:
     Increased S DNA content  Increased number of mitotic ce 

         1 MGI mutant phenotype (inferred from 1 allele(MGI details for Lrch2):
     normal 

    Find genes that share phenotypes with LRCH2           About GenesLikeMe

    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for LRCH2

    miRNA
    Products:
        
    miRTarBase miRNAs that target LRCH2:
    hsa-mir-335-5p (MIRT018027), hsa-mir-101-3p (MIRT027383)

    Block miRNA regulation of human, mouse, rat LRCH2 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate LRCH2 (see all 59):
    hsa-miR-4307 hsa-miR-139-5p hsa-miR-578 hsa-miR-301a hsa-miR-30d hsa-miR-519a hsa-miR-4275 hsa-miR-374a*
    SwitchGear 3'UTR luciferase reporter plasmidLRCH2 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat LRCH2

    Gene Editing
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    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for LRCH2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat LRCH2

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for LRCH2


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol3
    nucleus2
    plasma membrane1

    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for LRCH2
    Interactions:

        Search GeneGlobe Interaction Network for LRCH2

    STRING Interaction Network Preview (showing 3 interactants - click image to see more details)

    5 Interacting proteins for LRCH2 (Q5VUJ63 ENSP000003250914) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    COPS5Q929053, ENSP000003505124I2D: score=1 STRING: ENSP00000350512
    RPAP3Q9H6T33, ENSP000000053864I2D: score=1 STRING: ENSP00000005386
    RPAP2Q8IXW53I2D: score=1 
    YWHAEP622583I2D: score=1 
    --ENSP000003593684STRING: ENSP00000359368
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for LRCH2



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for LRCH2 gene (2 alternative transcripts): 
    NM_001243963.1  NM_020871.3  

    Unigene Cluster for LRCH2:

    Leucine-rich repeats and calponin homology (CH) domain containing 2
    Hs.65366  [show with all ESTs]
    Unigene Representative Sequence: BX647193
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000317135(uc010nqe.3 uc004epz.3) ENST00000538422
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat LRCH2 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate LRCH2 (see all 59):
    hsa-miR-4307 hsa-miR-139-5p hsa-miR-578 hsa-miR-301a hsa-miR-30d hsa-miR-519a hsa-miR-4275 hsa-miR-374a*
    SwitchGear 3'UTR luciferase reporter plasmidLRCH2 3' UTR sequence
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for LRCH2
    Predesigned siRNA for gene silencing in human, mouse, rat LRCH2
    Clone
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    OriGene clones in human, mouse for LRCH2 (see all 8)
    OriGene ORF clones in mouse, rat for LRCH2
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: LRCH2 (NM_020871)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for LRCH2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat LRCH2
    Primer
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    OriGene qSTAR qPCR primer pairs in human, mouse for LRCH2
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat LRCH2
      QuantiTect SYBR Green Assays in human, mouse, rat LRCH2
      QuantiFast Probe-based Assays in human, mouse, rat LRCH2

    Additional mRNA sequence: 

    AB040928.1 AK022128.1 BC042004.1 BC125223.1 BC125224.1 BX647193.1 

    2 DOTS entries:

    DT.408106  DT.121306180 

    Selected AceView cDNA sequences (see all 62):

    AI289313 Z40300 CD673145 AI014456 AB040928 BX505451 BU677917 AI401349 
    NM_020871 CR623574 T16722 BM710863 AU121179 BX105175 AW470144 AI335797 
    BX647193 BM667709 BM728364 AA419503 BX412741 CB113640 D61488 AW511018 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    LRCH2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GTCCCCTACA
    LRCH2 Expression
    About this image


    LRCH2 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 3) fully expand
     
     Placenta (Extraembryonic Tissues)    fully expand to see all 2 entries
             Placenta-derived mesenchymal stem cells (family)
     
     Mesenchymal Stem Cells (Uncategorized)    fully expand to see all 2 entries
             Placenta-derived mesenchymal stem cells (family)
     
     Blood (Hematopoietic System)
             Hematopoietic Stem Cells Hematopoietic Bone Marrow
    LRCH2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    LRCH2 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.65366
        Custom PCR Arrays for LRCH2
    Primer
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for LRCH2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for LRCH2 gene from Selected species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Lrch21 , 5 leucine-rich repeats and calponin homology (CH) domain more1, 5 90.56(n)1
    93.61(a)1
      X (68.46 cM)5
    2102971  NM_001081173.11  NP_001074642.11 
     1474703755 
    chicken
    (Gallus gallus)
    Aves LRCH21 leucine-rich repeats and calponin homology (CH) domain more 80.3(n)
    83.47(a)
      422220  XM_004940655.1  XP_004940712.1 
    lizard
    (Anolis carolinensis)
    Reptilia LRCH26
    leucine-rich repeats and calponin homology (CH) do...
    69(a)
    1 ↔ 1
    GL343403.1(677094-721894)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.338372 Xenopus laevis transcribed sequence with moderate similarity more 80.14(n)    AW646020.1 
    zebrafish
    (Danio rerio)
    Actinopterygii LOC1018826841 leucine-rich repeat and calponin homology domain-containing more 65.87(n)
    70.84(a)
      101882684  XM_005165448.1  XP_005165505.1 


    ENSEMBL Gene Tree for LRCH2 (if available)
    TreeFam Gene Tree for LRCH2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for LRCH2 gene
    LRRC22  LRRC182  LRSAM12  LRRC302  PIDD2  LRCH32  LRRC572  LRRC10B2  
    LRRC392  LRCH42  LRRC102  LRCH12  
    4 SIMAP similar genes for LRCH2 using alignment to 2 protein entries:     LRCH2_HUMAN (see all proteins):
    LRCH3    LRCH1    LRCH4    RSU1

    Find genes that share paralogs with LRCH2           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for LRCH2 (see all 1624)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr X posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1909443811,2
    --114326498(+) TTCCAG/TGTCAT 2 -- ds50010--------
    rs1823755471,2
    --114326525(+) AATGGC/TTGCAT 2 -- ds50010--------
    rs1404884341,2
    C--114326574(+) TCAGAC/TAGGCA 2 -- ds50010--------
    rs1878674181,2
    --114326650(+) CCAGCC/TTGACC 2 -- ds50010--------
    rs1911685621,2
    --114326970(+) TATGAC/TAGATC 2 -- ut310--------
    rs1834284741,2
    --114326996(+) CATTTA/CTGATT 2 -- ut310--------
    rs27528601,2
    C,F,O,A,H--114327119(+) CACTTC/GTTTCT 2 -- ut31 trp314Minor allele frequency- G:0.14NA NS EA WA 1386
    rs43781371,2
    C,H--114327328(+) TAAAAG/AAAATA 2 -- ut315Minor allele frequency- A:0.00NS EA NA 418
    rs1874635891,2
    --114327425(+) AACTGC/TCATGA 2 -- ut310--------
    rs1922671871,2
    --114327484(+) AAGAAC/TGCTAC 2 -- ut310--------

    HapMap Linkage Disequilibrium report for LRCH2 (114345179 - 114468635 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 7 variations for LRCH2:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv1448157CNV Deletion17803354
    nsv513764CNV Insertion21212237
    esv271901CNV Insertion20981092
    nsv520351CNV Gain19592680
    nsv511667CNV Gain21212237
    nsv516624CNV Gain19592680
    esv33994CNV Gain+Loss17666407

    Locus Specific Mutation Databases (LSDB): LRCH2

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing LRCH2
    DNA2.0 Custom Variant and Variant Library Synthesis for LRCH2

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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      --

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for LRCH2 gene, integrated from 10 sources (see all 12):
    (articles sorted by number of sources associating them with LRCH2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10819331)1, 2, 3 Nagase T.... Ohara O. (DNA Res. 2000)
    2. The DNA sequence of the human X chromosome. (PubMed id 15772651)1, 2 Ross M.T.... Bentley D.R. (Nature 2005)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    4. Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions. (PubMed id 24255178)1 Couzens A.L....Gingras A.C. (Sci Signal 2013)
    5. Human leucine-rich repeat proteins: a genome-wide bioinformatic categorization and functional analysis in innate immunity. (PubMed id 20616063)1 Ng A.C....Xavier R.J. (Proc. Natl. Acad. Sci. U.S.A. 2011)
    6. Leucine-rich repeat (LRR) proteins: integrators of pattern recognition and signaling in immunity. (PubMed id 21606681)1 Ng A. and Xavier R.J. (Autophagy 2011)
    7. LRCH proteins: a novel family of cytoskeletal regulators. (PubMed id 20805893)1 Foussard H....Payre F. (PLoS ONE 2010)
    8. Dynamics of cullin-RING ubiquitin ligase network revealed by systematic quantitative proteomics. (PubMed id 21145461)1 Bennett E.J....Harper J.W. (Cell 2010)
    9. Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (amp 2008)
    10. Systematic analysis of the protein interaction network for the human transcription machinery reveals the identity of the 7SK capping enzyme. (PubMed id 17643375)1 Jeronimo C.... Coulombe B. (Mol. Cell 2007)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 57631 HGNC: 29292 AceView: LRCH2 Ensembl:ENSG00000130224 euGenes: HUgn57631
    ECgene: LRCH2 H-InvDB: LRCH2

    (According to HUGE)
    About This Section

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    HUGE: KIAA1495

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for LRCH2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

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    Patent Information for LRCH2 gene:
    Search GeneIP for patents involving LRCH2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from genOway)
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