Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



LPL Gene

protein-coding   GIFtS: 73
GCID: GC08P019759

Lipoprotein Lipase


(Previous symbol: LIPD)
  See LPL-related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

Aliases
Lipoprotein Lipase1 2
LIPD1 2 3 5
EC 3.1.1.343 8
HDLCQ112 5
EC 3.1.18

External Ids:    HGNC: 66771   Entrez Gene: 40232   Ensembl: ENSG000001754457   OMIM: 6097085   UniProtKB: P068583   

Export aliases for LPL gene to outside databases

Previous GC identifers: GC08P019672 GC08P019859 GC08P019807 GC08P019841 GC08P018336


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

Entrez Gene summary for LPL Gene:
LPL encodes lipoprotein lipase, which is expressed in heart, muscle, and adipose tissue. LPL functions as a
homodimer, and has the dual functions of triglyceride hydrolase and ligand/bridging factor for receptor-mediated
lipoprotein uptake. Severe mutations that cause LPL deficiency result in type I hyperlipoproteinemia, while less
extreme mutations in LPL are linked to many disorders of lipoprotein metabolism. (provided by RefSeq, Jul 2008)

GeneCards Summary for LPL Gene:
LPL (lipoprotein lipase) is a protein-coding gene. Diseases associated with LPL include familial lipoprotein lipase deficiency, and familial combined hyperlipidemia. GO annotations related to this gene include triglyceride lipase activity and receptor binding. An important paralog of this gene is LIPH.

UniProtKB/Swiss-Prot: LIPL_HUMAN, P06858
Function: The primary function of this lipase is the hydrolysis of triglycerides of circulating chylomicrons and
very low density lipoproteins (VLDL). Binding to heparin sulfate proteogylcans at the cell surface is vital to
the function. The apolipoprotein, APOC2, acts as a coactivator of LPL activity in the presence of lipids on the
luminal surface of vascular endothelium (By similarity)

summary for LPL Gene:
Lipoprotein lipase (LPL), like LIPG, is a vascular lipase, however it is not synthesized in endothelial
cells. It is anchored to the capillary endothelium by proteoglycans and catalyzes the hydrolysis of
triglycerides to release free fatty acids into the circulation. LPL therefore initiates the processing of
triglyceride-rich lipoproteins such as chylomicrons and VLDL.

Gene Wiki entry for LPL (Lipoprotein lipase) Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence at NCBI GenBank:
NC_000008.10  NC_018919.2  NT_167187.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the LPL gene promoter:
         STAT1   Sp1   AP-1   ATF-2   Ik-2   COMP1   c-Jun   NF-kappaB1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidLPL promoter sequence
   Search Chromatin IP Primers for LPL

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat LPL


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 8p22   Ensembl cytogenetic band:  8p21.3   HGNC cytogenetic band: 8p22

LPL Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
LPL gene location

GeneLoc information about chromosome 8         GeneLoc Exon Structure

GeneLoc location for GC08P019759:  view genomic region     (about GC identifiers)

Start:
19,759,228 bp from pter      End:
19,824,770 bp from pter
Size:
65,543 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: LIPL_HUMAN, P06858 (See protein sequence)
Recommended Name: Lipoprotein lipase precursor  
Size: 475 amino acids; 53162 Da
Subunit: Homodimer (By similarity). Interacts with APOC2; the interaction activates LPL activity in the presence
of lipids. Interacts with GPIHBP1
Secondary accessions: B2R5T9 Q16282 Q16283 Q96FC4

Explore the universe of human proteins at neXtProt for LPL: NX_P06858

Explore proteomics data for LPL at MOPED

Post-translational modifications: 

  • Tyrosine nitration after lipopolysaccharide (LPS) challenge down-regulates the lipase activity (By similarity)1
  • Glycosylation2 at Asn70, Asn386
  • Modification sites at PhosphoSitePlus
  • Selected DME Specific Peptides for LPL (P06858) (see all 25)
     SHLQKGK  RLSPDDA  VDWLSRA  KCSHERS 


    See LPL Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_000228.1  
    ENSEMBL proteins: 
     ENSP00000428496   ENSP00000428237   ENSP00000428557   ENSP00000309757   ENSP00000431028  
    Reactome Protein details: P06858

    LPL Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Protein for LPL
    OriGene Protein Over-expression Lysate for LPL
    OriGene MassSpec for LPL
    OriGene Custom Protein Services for LPL
    GenScript Custom Purified and Recombinant Proteins Services for LPL
    Novus Biologicals LPL Protein
    Novus Biologicals LPL Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    ProSpec Recombinant Protein for LPL
    Browse Proteins at Cloud-Clone Corp.

     
    Search eBioscience for Proteins for LPL 

     
    antibodies-online proteins for LPL (14 products) 

     
    antibodies-online peptides for LPL

    LPL Antibody Products:

    EMD Millipore Mono- and Polyclonal Antibodies for the study of LPL
    R&D Systems Antibodies for LPL (Lipoprotein Lipase/LPL)
    OriGene Antibodies for LPL
    OriGene Custom Antibody Services for LPL
    Novus Biologicals LPL Antibodies
    Abcam antibodies for LPL
    Browse Antibodies at Cloud-Clone Corp.
    ThermoFisher Antibodies for LPL
    antibodies-online antibodies for LPL (95 products) 

    LPL Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for LPL
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for LPL
    Browse Enzo Life Sciences for kits & assays
    Browse ELISAs at Cloud-Clone Corp.
    Browse CLIAs at Cloud-Clone Corp.
    Search eBioscience for ELISAs for LPL 
    antibodies-online kits for LPL (41 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus
    Selected InterPro protein domains (see all 6):
     IPR000734 Lipase
     IPR016272 Lipoprotein_lipase_LIPH
     IPR001024 PLAT/LH2_dom
     IPR008976 Lipase_LipOase
     IPR013818 Lipase_N

    Graphical View of Domain Structure for InterPro Entry P06858

    ProtoNet protein and cluster: P06858

    4 Blocks protein domains:
    IPB000734 Lipase
    IPB001024 Lipoxygenase
    IPB002330 Lipoprotein lipase signature
    IPB008262 Lipase


    UniProtKB/Swiss-Prot: LIPL_HUMAN, P06858
    Similarity: Belongs to the AB hydrolase superfamily. Lipase family
    Similarity: Contains 1 PLAT domain


    Find genes that share domains with LPL           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: LIPL_HUMAN, P06858
    Function: The primary function of this lipase is the hydrolysis of triglycerides of circulating chylomicrons and
    very low density lipoproteins (VLDL). Binding to heparin sulfate proteogylcans at the cell surface is vital to
    the function. The apolipoprotein, APOC2, acts as a coactivator of LPL activity in the presence of lipids on the
    luminal surface of vascular endothelium (By similarity)
    Catalytic activity: Triacylglycerol + H(2)O = diacylglycerol + a carboxylate

         Genatlas biochemistry entry for LPL:
    lipoprotein lipase,50.4kDa,serine esterase with high homology to LIPC,PNLIP,expressed in adipocytes,striated
    muscle,located on the luminal surface of capillary endothelial cells,involved in plasma lipid transport

         Enzyme Numbers (IUBMB): EC 3.1.1.341 2 EC 3.1.12

         Gene Ontology (GO): Selected molecular function terms (see all 8):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004465lipoprotein lipase activity ISS10727238
    GO:0004620phospholipase activity ISS10727238
    GO:0004806triglyceride lipase activity ISS10727238
    GO:0005102receptor binding IPI10085125
    GO:0005515protein binding IPI--
         
    Find genes that share ontologies with LPL           About GenesLikeMe


    Phenotypes:
         5 GenomeRNAi human phenotypes for LPL:
     Decreased Tat-dependent transc  Decreased p24 protein expressi  G0/1 arrest  Increased G1 DNA content 
     Increased gamma-H2AX phosphory 

         9 MGI mutant phenotypes (inferred from 3 alleles(MGI details for Lpl):
     adipose tissue  cardiovascular system  growth/size/body  homeostasis/metabolism  integument 
     liver/biliary system  mortality/aging  muscle  respiratory system 

    Find genes that share phenotypes with LPL           About GenesLikeMe

    Animal Models:
         MGI mouse knock-outs for LPL: Lpltm1Sem Lpltm1Bres

       genOway: Develop your customized and physiologically relevant rodent model for LPL

    miRNA
    Products:
        
    miRTarBase miRNAs that target LPL:
    hsa-mir-148b-3p (MIRT019335), hsa-mir-155-5p (MIRT001542), hsa-mir-138-5p (MIRT005491), hsa-mir-29a-3p (MIRT005584), hsa-let-7b-5p (MIRT032343)

    Block miRNA regulation of human, mouse, rat LPL using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate LPL (see all 9):
    hsa-miR-588 hsa-miR-27a hsa-miR-29a hsa-miR-29c hsa-miR-3672 hsa-miR-1303 hsa-miR-590-3p hsa-miR-27b
    SwitchGear 3'UTR luciferase reporter plasmidLPL 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for LPL
    Predesigned siRNA for gene silencing in human, mouse, rat LPL

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for LPL

    Clone
    Products:
         
    OriGene clones in human, mouse for LPL (see all 7)
    OriGene ORF clones in mouse, rat for LPL
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 3): LPL (NM_000478)
    Sino Biological Human cDNA Clone for LPL
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for LPL
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat LPL

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for LPL
    Browse ESI BIO Cell Lines and PureStem Progenitors for LPL 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for LPL


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from UniProtKB/Swiss-Prot
    LIPL_HUMAN, P06858: Cell membrane (By similarity); Lipid-anchor, GPI-anchor (By similarity). Secreted (By
    similarity). Note=Locates to the plasma membrane of microvilli of hepatocytes with triacyl-glycerol-rich
    lipoproteins (TRL). Some of the bound LPL is then internalized and located inside non-coated endocytic vesicles
    (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    extracellular4
    endoplasmic reticulum2
    mitochondrion2
    nucleus2
    peroxisome2
    plasma membrane2
    cytoskeleton1
    cytosol1
    golgi apparatus1
    lysosome1

    Gene Ontology (GO): Selected cellular component terms (see all 8):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576extracellular region TAS--
    GO:0005615extracellular space IDA12573449
    GO:0005886plasma membrane IEA--
    GO:0009986cell surface IEA--
    GO:0031012extracellular matrix IEA--

    Find genes that share ontologies with LPL           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus

    SuperPaths for LPL About   (see all 16)  
    See pathways by source

    SuperPathContained pathways About
    1Statin Pathway
    Statin Pathway0.73
    Statin Pathway, Pharmacodynamics0.73
    2Alzheimer's disease
    Alzheimers Disease0.44
    Alzheimer's disease0.44
    3Lipoprotein metabolism
    Lipoprotein metabolism0.59
    Chylomicron-mediated lipid transport0.00
    Lipid digestion, mobilization, and transport0.59
    4Diseases associated with visual transduction
    Visual phototransduction0.44
    Diseases associated with visual transduction0.43
    Retinoid metabolism and transport0.44
    5Metabolism
    Metabolism0.38
    Metabolism of lipids and lipoproteins0.37


    Find genes that share SuperPaths with LPL           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    Selected BioSystems Pathways for LPL (see all 7)
        Adipogenesis
    Vitamin A and carotenoid metabolism
    Statin Pathway
    SREBP signalling
    Fatty Acid Beta Oxidation


    3 Reactome Pathways for LPL
        Transcriptional regulation of white adipocyte differentiation
    Retinoid metabolism and transport
    Chylomicron-mediated lipid transport

    1 PharmGKB Pathway for LPL
        Statin Pathway, Pharmacodynamics

    3 Kegg Pathways  (Kegg details for LPL):
        Glycerolipid metabolism
    PPAR signaling pathway
    Alzheimer's disease

        Pathway & Disease-focused RT2 Profiler PCR Arrays including LPL (see all 12): 
              Fatty Acid Metabolism in human mouse rat
              Cancer PathwayFinder in human mouse rat
              Alzheimer's Disease in human mouse rat
              Hepatotoxicity in human mouse rat
              Adipogenesis in human mouse rat

    Interactions:

        GeneGlobe Interaction Network for LPL

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for LPL (P068582, 3 ENSP000003097574) via UniProtKB, MINT, STRING, and/or I2D (see all 98)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    C7orf55-LUC7L2Q9Y3832, 3MINT-63419 I2D: score=5 
    LUC7L2Q9Y3832, 3MINT-63419 I2D: score=5 
    ASCC2Q9H1I82, 3MINT-65463 I2D: score=5 
    COPS6Q7L5N12, 3MINT-63416 I2D: score=5 
    KIAA1377Q9P2H02, 3MINT-63418 I2D: score=5 
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 19):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001523retinoid metabolic process TAS--
    GO:0006629lipid metabolic process ----
    GO:0006633fatty acid biosynthetic process ISS--
    GO:0006641triglyceride metabolic process ISS10727238
    GO:0006644phospholipid metabolic process ISS10727238

    Find genes that share ontologies with LPL           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Compounds for LPL available from Tocris Bioscience    About this table
    CompoundAction CAS #
    JZL 184Monoacylglycerol lipase (MAGL) inhibitor[1101854-58-3]
    Orlistat Pancreatic, gastric and carboxylester lipase inhibitor; antiobesity and antihypercholesterolemic activity [96829-58-2]
    Pristimerin Potent, reversible MAGL inhibitor [1258-84-0]
    GSK 264220AEndothelial lipase and lipoprotein lipase inhibitor[685506-42-7]

    Selected HMDB Compounds for LPL (see all 1143)    About this table
    CompoundSynonyms CAS #PubMed Ids
    Arachidic acidArachate (see all 10)506-30-9--
    Arachidonic acid5,8,11,14-Eicosatetraenoic acid (see all 16)506-32-1--
    DG(14:0/14:0/0:0)DAG(14:0/14:0) (see all 9)----
    DG(14:0/14:1(9Z)/0:0)DAG(14:0/14:1) (see all 15)----
    DG(14:0/15:0/0:0)Diacylglycerol(29:0) (see all 9)----
    DG(14:0/16:0/0:0)DAG(30:0) (see all 9)----
    DG(14:0/16:1(9Z)/0:0)DG(30:1) (see all 15)----
    DG(14:0/18:0/0:0)DG(14:0/18:0) (see all 9)----
    DG(14:0/18:1(11Z)/0:0)Diacylglycerol (see all 15)----
    DG(14:0/18:1(9Z)/0:0)1-myristoyl-2-oleoyl-sn-glycerol (see all 15)----

    1 DrugBank Compound for LPL    About this table
    CompoundSynonyms CAS #TypeActionsPubMed Ids
    Tyloxapol-- 25301-02-4targetinhibitor9406449 16839786 1493594

    Selected Novoseek inferred chemical compound relationships for LPL gene (see all 121)    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    lipid 84.5 682 10727238 (6), 8908157 (4), 1466662 (3), 1401083 (3) (see all 99)
    cholesterol 84.2 415 1501422 (5), 9193431 (4), 10785873 (4), 8857920 (4) (see all 99)
    triacylglycerol 79 148 10403579 (4), 18751379 (4), 2375781 (3), 11971937 (3) (see all 71)
    cholesterol ester 76.5 55 8645351 (4), 9627145 (3), 12919138 (2), 11284423 (2) (see all 33)
    hind iii 76.4 81 16364275 (3), 18590804 (3), 1466662 (2), 15189363 (2) (see all 47)
    fatty acid 74.1 215 20410100 (3), 16307734 (3), 1894793 (2), 8166251 (2) (see all 99)
    heparin 71.2 378 7811745 (7), 12960955 (7), 15527497 (7), 8810923 (6) (see all 99)
    asp 250 70.5 6 8973094 (1), 1619366 (1), 7706936 (1)
    glycerol 3-phosphate 64.7 41 8928727 (1), 9062891 (1), 17406767 (1), 1411264 (1) (see all 26)
    glucose 63.5 211 9414485 (5), 16555944 (5), 9519750 (4), 9239412 (3) (see all 99)

    1 PharmGKB related drug/compound annotation for LPL gene    About this table
    Drug/compound PharmGKB Annotation
    pravastatinCA  



    Find genes that share compounds with LPL           About GenesLikeMe



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for LPL gene: 
    NM_000237.2  

    Unigene Cluster for LPL:

    Lipoprotein lipase
    Hs.180878  [show with all ESTs]
    Unigene Representative Sequence: NM_000237
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000520959 ENST00000524029 ENST00000522701 ENST00000311322(uc003wzk.4)
    ENST00000519773 ENST00000521994 ENST00000523696
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat LPL using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate LPL (see all 9):
    hsa-miR-588 hsa-miR-27a hsa-miR-29a hsa-miR-29c hsa-miR-3672 hsa-miR-1303 hsa-miR-590-3p hsa-miR-27b
    SwitchGear 3'UTR luciferase reporter plasmidLPL 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for LPL
    Predesigned siRNA for gene silencing in human, mouse, rat LPL
    Clone
    Products:
         
    OriGene clones in human, mouse for LPL (see all 7)
    OriGene ORF clones in mouse, rat for LPL
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 3): LPL (NM_000478)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for LPL
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat LPL
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for LPL
    OriGene qSTAR qPCR primer pairs in human, mouse for LPL
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat LPL
      QuantiTect SYBR Green Assays in human, mouse, rat LPL
      QuantiFast Probe-based Assays in human, mouse, rat LPL

    Additional mRNA sequence: 

    AK092286.1 AK222464.1 AK290290.1 AK297164.1 AK312311.1 BC011353.1 BT006726.1 CR457054.1 
    M15856.1 M26380.1 S78266.1 X14390.1 X54516.1 

    17 DOTS entries:

    DT.119216  DT.101963630  DT.100807358  DT.120638148  DT.99974904  DT.120638161  DT.95073909  DT.120638185 
    DT.100687418  DT.100824351  DT.120638144  DT.120638147  DT.120638154  DT.120638156  DT.120638198  DT.92440268 
    DT.95073943 

    Selected AceView cDNA sequences (see all 338):

    CA406476 CF551941 AU121893 N94946 H27789 CB269806 BE503153 AU100389 
    AW300544 BE670101 AU102372 AW149478 BQ187420 F02348 BM998326 AW298739 
    CK300728 BE222266 W37182 BX102664 NM_000237 CB269446 AU122755 CA406910 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for LPL    About this scheme

    ExUns: 1 ^ 2a · 2b ^ 3a · 3b ^ 4a · 4b · 4c · 4d ^ 5 ^ 6 ^ 7a · 7b ^ 8a · 8b ^ 9 ^ 10 ^ 11
    SP1:                                -                                                                           
    SP2:        -                       -                                                                           
    SP3:                          -     -     -     -     -     -     -     -                                       
    SP4:                                                                                                            


    ECgene alternative splicing isoforms for LPL

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    LPL expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TGTGGATGTG
    LPL Expression
    About this image


    LPL expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 15) fully expand
     
     Adipose (Muscoskeletal System)    fully expand to see all 11 entries
             Subcutaneous White Adipocytes Cranial Subcutaneous White Adipose
             Adipocyte-like cells
     
     Bone (Muscoskeletal System)    fully expand to see all 4 entries
             Mesenchymal Condensate Cells Zeugopod
             Zeugopod Long Bone
             HyStem+BMP4-induced E15 cells
     
     Cartilage (Muscoskeletal System)    fully expand to see all 3 entries
             Mesenchymal Condensate Cells Zeugopod
             HyStem+BMP4-induced E15 cells
     
     Limb (Muscoskeletal System)    fully expand to see all 6 entries
             Bone Marrow Stromal Cells Pelvic Girdle
             Zeugopod
     
     Brain (Nervous System)    fully expand to see all 4 entries
             Adult Dopaminergic Neurons Ventral Tegmental Area
             Midbrain tegmentum
    LPL Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    LPL Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.180878
        Pathway & Disease-focused RT2 Profiler PCR Arrays including LPL (see all 12): 
              Fatty Acid Metabolism in human mouse rat
              Cancer PathwayFinder in human mouse rat
              Alzheimer's Disease in human mouse rat
              Hepatotoxicity in human mouse rat
              Adipogenesis in human mouse rat

    Primer
    Products:
    OriGene qPCR primer pairs and template standards for LPL
    OriGene qSTAR qPCR primer pairs in human, mouse for LPL
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat LPL
    QuantiTect SYBR Green Assays in human, mouse, rat LPL
    QuantiFast Probe-based Assays in human, mouse, rat LPL
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for LPL

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of animals.

    Orthologs for LPL gene from Selected species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Lpl1 , 5 lipoprotein lipase1, 5 88.05(n)1
    93.04(a)1
      8 (33.88 cM)5
    169561  NM_008509.21  NP_032535.21 
     688804915 
    chicken
    (Gallus gallus)
    Aves LPL1 lipoprotein lipase 73.36(n)
    75.38(a)
      396219  NM_205282.1  NP_990613.1 
    lizard
    (Anolis carolinensis)
    Reptilia LPL6
    lipoprotein lipase
    64(a)
    1 ↔ 1
    2(75017732-75035688)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia lpl1 lipoprotein lipase 71.18(n)
    72.47(a)
      100127862  XM_002933992.2  XP_002934038.1 
    zebrafish
    (Danio rerio)
    Actinopterygii lpl2 lipoprotein lipase 78.06(n)   30354  BC064296.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG19863 lipoprotein lipase 36(a)
    (best of 3)
      9A3   --


    ENSEMBL Gene Tree for LPL (if available)
    TreeFam Gene Tree for LPL (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
    Paralogs for LPL gene
    LIPH2  LIPC2  LIPG2  PNLIPRP32  PNLIPRP22  PNLIP2  LIPI2  PLA1A2  
    PNLIPRP12  
    5 SIMAP similar genes for LPL using alignment to 7 protein entries:     LIPL_HUMAN (see all proteins):
    LIPG    LIPC    PNLIPRP1    PNLIP    PNLIPRP2

    Find genes that share paralogs with LPL           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    Selected SNPs for LPL (see all 934)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 8 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs18011771,2,,4
    C,FLipoprotein lipase deficiency (LPL deficiency)4 pathogenic120057692(+) TTATCG/AACATC 2 /N /D mis18Minor allele frequency- A:0.03NS NA EU WA 6811
    rs354147001,2,,4
    CLipoprotein lipase deficiency (LPL deficiency)4 --20065396(-) TCAACA/CGAGAG 2 R L mis13Minor allele frequency- C:0.01NA 80
    rs2681,2,,4
    C,F,HLipoprotein lipase deficiency (LPL deficiency)4 pathogenic120065513(+) GATCAA/GTAAAG 2 N S mis118Minor allele frequency- G:0.01MN NA NS EA EU 7603
    VAR_0579144
    Lipoprotein lipase deficiency (LPL deficiency)4--see VAR_0579142 N S mis40--------
    VAR_0579344
    Lipoprotein lipase deficiency (LPL deficiency)4--see VAR_0579342 Y H mis40--------
    VAR_0579404
    Lipoprotein lipase deficiency (LPL deficiency)4--see VAR_0579402 S R mis40--------
    VAR_0579204
    Lipoprotein lipase deficiency (LPL deficiency)4--see VAR_0579202 D H mis40--------
    VAR_0579224
    Lipoprotein lipase deficiency (LPL deficiency)4--see VAR_0579222 E G mis40--------
    VAR_0042254
    Lipoprotein lipase deficiency (LPL deficiency)4--see VAR_0042252 G E mis40--------
    VAR_0042224
    Lipoprotein lipase deficiency (LPL deficiency)4--see VAR_0042222 A T mis40--------

    HapMap Linkage Disequilibrium report for LPL (19759228 - 19824770 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 5 variations for LPL:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv890632CNV Loss21882294
    esv32767CNV Loss17666407
    nsv890625CNV Gain21882294
    nsv515694CNV Gain19592680
    nsv522185CNV Gain19592680

    Human Gene Mutation Database (HGMD): LPL
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing LPL
    DNA2.0 Custom Variant and Variant Library Synthesis for LPL

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus
    OMIM gene information: 609708   
    OMIM disorders: 238600  144250  
    UniProtKB/Swiss-Prot: LIPL_HUMAN, P06858
  • Lipoprotein lipase deficiency (LPL deficiency) [MIM:238600]: Recessive disorder usually manifesting in
    childhood. On a normal diet, patients often present with abdominal pain, hepatosplenomegaly, lipemia retinalis,
    eruptive xanthomata, and massive hypertriglyceridemia, sometimes complicated with acute pancreatitis. Note=The
    disease is caused by mutations affecting the gene represented in this entry

  • Selected diseases for LPL (see all 22):    
    About MalaCards
    familial lipoprotein lipase deficiency    familial combined hyperlipidemia    hyperlipoproteinemia type v    familial combined hyperlipoproteinemia
    lipid metabolism disorder    hepatic lipase deficiency    biotinidase deficiency    hyperapobetalipoproteinemia
    boutonneuse fever    familial hypertriglyceridemia    wrinkles    tangier disease
    hypertriglyceridemia    hyperlipoproteinemia type iii    hypoalphalipoproteinemia    carotid intimal medial thickness
    pancreatitis    steatorrhea    hyperalphalipoproteinemia    familial hyperlipidemia

    11 diseases from the University of Copenhagen DISEASES database for LPL:
    Familial hyperlipidemia     Atherosclerosis     Diabetes mellitus     Familial hypertriglyceridemia
    Coronary heart disease     Pancreatitis     Hyperinsulinism     Hypertension
    Hyperglycemia     Kidney disease     Ischemic heart disease

    Find genes that share disorders with LPL           About GenesLikeMe

    Selected Novoseek inferred disease relationships for LPL gene (see all 96)    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    endogenous hypertriglyceridemia 93.3 95 7811743 (3), 10481930 (2), 1619366 (2), 1907278 (2) (see all 64)
    hypertriglyceridemia 91.4 312 10560236 (5), 8675619 (4), 10619999 (3), 17919884 (3) (see all 99)
    hypertriglyceridemias familial 83.1 26 7609317 (3), 15534935 (1), 9209790 (1), 9629518 (1) (see all 16)
    hyperlipidemia familial combined 81.3 23 8551675 (1), 16822320 (1), 1619366 (1), 8049185 (1) (see all 13)
    dyslipidemia 76.4 53 16741292 (3), 19639021 (2), 8790727 (2), 15262189 (2) (see all 33)
    hyperlipidemia 74.9 63 14660566 (2), 16606335 (2), 9382958 (2), 1968704 (2) (see all 39)
    atherosclerosis 72.7 152 15639492 (4), 10484615 (4), 15545743 (3), 8692976 (3) (see all 75)
    hyperlipoproteinemia 72.3 15 8682644 (2), 14669227 (2), 1943724 (2), 11194013 (1) (see all 9)
    hyperlipoproteinemia type iii 71.4 16 19233944 (2), 1430218 (2), 2259550 (1), 7583546 (1) (see all 9)
    lipoprotein disorder 70.9 4 15719845 (1), 1417963 (1), 9185775 (1), 11122693 (1)

    Genatlas disease: LPL
    human blood pressure QTL at or near the lipoprotein lipase gene,accounting for 52-73% of variation in systolic bp
    in the data set (Taiwanese population)

    GeneTests: LPL
    GeneReviews: LPL
    Genetic Association Database (GAD): LPL
    Human Genome Epidemiology (HuGE) Navigator: LPL (355 documents)

    Export disorders for LPL gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for LPL gene, integrated from 10 sources (see all 2170):
    (articles sorted by number of sources associating them with LPL)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Characterization of the human lipoprotein lipase (LPL) promoter: evidence of two cis-regulatory regions, LP-alpha and LP-beta, of importance for the differentiation-linked induction of the LPL gene during adipogenesis. (PubMed id 1406652)1, 2, 9 Enerbaeck S.... Bjursell G. (Mol. Cell. Biol. 1992)
    2. Genetic association study of selected candidate genes (ApoB, LPL, Leptin) and telomere length in obese and hypertensive individuals. (PubMed id 19772655)1, 4, 9 Das B....Seshadri M. (BMC Med. Genet. 2009)
    3. Lipoprotein lipase mutation S447X associated with pancreatic calcification and steatorrhea in hyperlipidemic pancreatitis. (PubMed id 19034041)1, 4, 9 Chang Y.T....Wong J.M. (J. Clin. Gastroenterol. 2009)
    4. Apolipoprotein E and lipoprotein lipase gene polymorphisms interaction on the atherogenic combined expression of hypertriglyceridemia and hyperapobetalipoproteinemia phenotypes. (PubMed id 17848837)1, 4, 9 Perron P....Gaudet D. (J. Endocrinol. Invest. 2007)
    5. Associations between HDL-cholesterol and polymorphisms in hepatic lipase and lipoprotein lipase genes are modified by dietary fat intake in African American and White adults. (PubMed id 17157861)1, 4, 9 Nettleton J.A....Folsom A.R. (Atherosclerosis 2007)
    6. Haplotypes in the lipoprotein lipase gene influence fasting insulin and discovery of a new risk haplotype. (PubMed id 17032721)1, 4, 9 Goodarzi M.O....Rotter J.I. (J. Clin. Endocrinol. Metab. 2007)
    7. Lack of relationship in long-term type 1 diabetic patients between diabetic nephropathy and polymorphisms in apolipoprotein epsilon, lipoprotein lipase and cholesteryl ester transfer protein. GenActique de la Nephropathie DiabActique Study Group. DonnAces EpidAcmiologiques sur le Syndrome d'Insulino-RAcsistance Study Group. (PubMed id 11096142)1, 4, 9 Hadjadj S....Marre M. (Nephrol. Dial. Transplant. 2000)
    8. Associations for lipoprotein lipase and peroxisome proliferator-activated receptor-gamma gene and coronary artery disease in an Indian population. (PubMed id 20430250)1, 4, 9 AshokKumar M....Emmanuel C. (Arch. Med. Res. 2010)
    9. Genetic variation in APOJ, LPL, and TNFRSF10B affects plasma fatty acid distribution in Alaskan Eskimos. (PubMed id 20410100)1, 4, 9 Voruganti V.S....Comuzzie A.G. (Am. J. Clin. Nutr. 2010)
    10. Diagnostic value of post-heparin lipase testing in detecting common genetic variants in the LPL and LIPC genes. (PubMed id 19367320)1, 4, 9 van Hoek M....Sijbrands E.J. (Eur. J. Hum. Genet. 2009)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Disorders
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 4023 HGNC: 6677 AceView: LPL Ensembl:ENSG00000175445 euGenes: HUgn4023
    ECgene: LPL Kegg: 4023 H-InvDB: LPL

    (According to HUGE)
    About This Section

    TryGeneCards Plus
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for LPL Pharmacogenomics, SNPs, Pathways
    GeneReviewshttp://www.ncbi.nlm.nih.gov/books/NBK1116/?term=LPL[genesymbol]
    SHMPDhttp://shmpd.bii.a-star.edu.sg/gene.php?genestart=A&genename=LPL
    Wikipedia http://en.wikipedia.org/wiki/Lipoprotein_lipase

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for LPL gene:
    Search GeneIP for patents involving LPL

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from genOway)
    About This Section

    TryGeneCards Plus

     EMD Millipore Mono- and Polyclonal Antibodies for the study of LPL
     Browse Purified and Recombinant Proteins at EMD Millipore
     Browse Small Molecules at EMD Millipore
     Browse Kits and Assays available from EMD Millipore
     
     EMD Millipore genomic analysis products

      
     Antibodies for LPL (Lipoprotein Lipase/LPL)   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     OriGene Antibodies for LPL   OriGene RNAi products in human, mouse, rat for LPL  
     OriGene qPCR primer pairs and template standards for LPL   OriGene Protein Over-expression Lysate for LPL  
     OriGene MassSpec for LPL   OriGene clones in human, mouse for LPL  
     OriGene qSTAR qPCR primer pairs in human, mouse for LPL   OriGene Purified Protein for LPL  
     OriGene ORF clones in mouse, rat for LPL   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for LPL   OriGene Custom Protein Services for LPL  

     
     
     Block miRNA regulation of human, mouse, rat LPL using miScript Target Protectors SeqTarget long-range PCR primers for resequencing LPL
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat LPL Predesigned siRNA for gene silencing in human, mouse, rat LPL
     QuantiFast Probe-based Assays in human, mouse, rat LPL QuantiTect SYBR Green Assays in human, mouse, rat LPL
     PCR Arrays including human, mouse, rat LPL Search Chromatin IP Primers for LPL
     Pre-validated RT2 qPCR Primer Assay in human, mouse, rat LPL  GeneGlobe Interaction Network for LPL
     Regulatory tfbs in LPL promoter
     GenScript Custom Purified and Recombinant Proteins Services for LPL GenScript cDNA clones with any tag delivered in your preferred vector for LPL
     GenScript Custom Assay Services for LPL GenScript Custom overexpressing Cell Line Services for LPL
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Tocris compounds for LPL
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     cDNA Clones for LPL
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     LPL antibodies
     LPL proteins
     LPL lysates
     Antibodies for LPL
     See all of Abcam's Antibodies, Kits and Proteins for LPL
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Recombinant Protein for LPL
     Browse Proteins at Cloud-Clone Corp.
     Browse Antibodies at Cloud-Clone Corp.
     Browse ELISAs at Cloud-Clone Corp.
     Browse CLIAs at Cloud-Clone Corp.



     Browse ESI BIO Cell Lines and PureStem Progenitors for LPL
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for LPL
     SwitchGear 3'UTR luciferase reporter plasmids for LPL
     SwitchGear Promoter luciferase reporter plasmids for LPL
     ThermoFisher Antibodies for LPL
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat LPL
     Browse compounds at ApexBio
     Search Addgene for plasmids for LPL
      Search eBioscience for proteins for LPL
      Search eBioscience for elisas for LPL
      eBioscience FlowRNA Probe Sets
     genOway: Develop your customized and physiologically relevant rodent model for LPL
     antibodies-online antibodies for LPL (95 products)
     antibodies-online kits for LPL (41 products)
     antibodies-online peptides for LPL
     antibodies-online proteins for LPL (14 products)
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014 , 7 Oct 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      LPL gene at Home site.
    Version: 3.12.258 10 Dec 2014
    hostname: 356980-web2.xennexinc.com index build: 128 solr: 1.4