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Aliases for LPCAT1 Gene

Aliases for LPCAT1 Gene

  • Lysophosphatidylcholine Acyltransferase 1 2 3 5
  • Acetyl-CoA:Lyso-Platelet-Activating Factor Acetyltransferase 3 4
  • 1-Alkylglycerophosphocholine O-Acetyltransferase 3 4
  • 1-Acylglycerophosphocholine O-Acyltransferase 3 4
  • Phosphonoformate Immuno-Associated Protein 3 3 4
  • Acetyl-CoA:Lyso-PAF Acetyltransferase 3 4
  • Lyso-PAF Acetyltransferase 3 4
  • LysoPC Acyltransferase 1 3 4
  • Acyltransferase-Like 2 3 4
  • LPC Acyltransferase 1 3 4
  • LysoPAFAT 3 4
  • LPCAT-1 3 4
  • PFAAP3 3 4
  • AYTL2 3 4
  • Acyltransferase Like 2 2
  • EC 2.3.1.23 4
  • EC 2.3.1.67 4
  • AGPAT10 3
  • AGPAT9 3
  • Lpcat 3

External Ids for LPCAT1 Gene

Previous HGNC Symbols for LPCAT1 Gene

  • AYTL2

Previous GeneCards Identifiers for LPCAT1 Gene

  • GC05M001516

Summaries for LPCAT1 Gene

Entrez Gene Summary for LPCAT1 Gene

  • This gene encodes a member of the 1-acyl-sn-glycerol-3-phosphate acyltransferase family of proteins. The encoded enzyme plays a role in phospholipid metabolism, specifically in the conversion of lysophosphatidylcholine to phosphatidylcholine in the presence of acyl-CoA. This process is important in the synthesis of lung surfactant and platelet-activating factor (PAF). Elevated expression of this gene may contribute to the progression of oral squamous cell, prostate, breast, and other human cancers. [provided by RefSeq, Sep 2016]

GeneCards Summary for LPCAT1 Gene

LPCAT1 (Lysophosphatidylcholine Acyltransferase 1) is a Protein Coding gene. Diseases associated with LPCAT1 include Retinitis Pigmentosa. Among its related pathways are Metabolism and Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha). GO annotations related to this gene include calcium ion binding and 1-acylglycerophosphocholine O-acyltransferase activity. An important paralog of this gene is LPCAT2.

UniProtKB/Swiss-Prot for LPCAT1 Gene

  • Possesses both acyltransferase and acetyltransferase activities (PubMed:16864775, PubMed:21498505). Activity is calcium-independent (By similarity). Mediates the conversion of 1-acyl-sn-glycero-3-phosphocholine (LPC) into phosphatidylcholine (PC) (PubMed:21498505). Displays a clear preference for saturated fatty acyl-CoAs, and 1-myristoyl or 1-palmitoyl LPC as acyl donors and acceptors, respectively (PubMed:16704971). May synthesize phosphatidylcholine in pulmonary surfactant, thereby playing a pivotal role in respiratory physiology (PubMed:16864775). Involved in the regulation of lipid droplet number and size (PubMed:25491198).

Additional gene information for LPCAT1 Gene

No data available for CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for LPCAT1 Gene

Genomics for LPCAT1 Gene

Regulatory Elements for LPCAT1 Gene

Enhancers for LPCAT1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH05H001484 1.7 FANTOM5 Ensembl ENCODE dbSUPER 30 +37.8 37847 7 HDGF PKNOX1 TBL1XR1 RB1 SIN3A BATF ZNF143 ZNF207 FOS ATF7 LPCAT1 SLC6A3 SLC12A7 GC05M001507
GH05H001492 1.7 FANTOM5 Ensembl ENCODE dbSUPER 28.7 +29.5 29520 8 HDGF PKNOX1 TBL1XR1 RB1 SIN3A RAD21 ZNF143 ZNF207 ATF7 ETV6 LPCAT1 SLC6A3 ZDHHC11B LOC728613 GC05M001507
GH05H001500 1.8 FANTOM5 Ensembl ENCODE dbSUPER 13.3 +22.1 22114 6 HDAC1 HDGF PKNOX1 SIN3A FEZF1 TCF12 GLIS2 SCRT2 ZNF143 ETV6 LPCAT1 SLC6A3 TERT ZDHHC11B SLC12A7 GC05M001507
GH05H001476 1.7 FANTOM5 Ensembl ENCODE dbSUPER 8.8 +46.2 46168 5 HDGF RB1 ZBTB7B RAD21 ZNF143 RUNX3 CREM IKZF2 EGR2 CEBPB SLC6A3 LPCAT1 BRD9P2 GC05M001507
GH05H001511 1.8 FANTOM5 Ensembl ENCODE dbSUPER 7.1 +9.7 9727 9 PKNOX1 ZFP64 SIN3A ZBTB7B GLIS2 FOS TSHZ1 ZNF592 SREBF1 GLIS1 SLC6A3 TERT SLC6A18 LPCAT1 CTD-3080P12.3 SLC12A7 MIR6075
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around LPCAT1 on UCSC Golden Path with GeneCards custom track

Genomic Location for LPCAT1 Gene

Chromosome:
5
Start:
1,456,480 bp from pter
End:
1,525,730 bp from pter
Size:
69,251 bases
Orientation:
Minus strand

Genomic View for LPCAT1 Gene

Genes around LPCAT1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
LPCAT1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for LPCAT1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for LPCAT1 Gene

Proteins for LPCAT1 Gene

  • Protein details for LPCAT1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8NF37-PCAT1_HUMAN
    Recommended name:
    Lysophosphatidylcholine acyltransferase 1
    Protein Accession:
    Q8NF37
    Secondary Accessions:
    • Q1HAQ1
    • Q7Z4G6
    • Q8N3U7
    • Q8WUL8
    • Q9GZW6

    Protein attributes for LPCAT1 Gene

    Size:
    534 amino acids
    Molecular mass:
    59151 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAB14061.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=BAB14065.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};

neXtProt entry for LPCAT1 Gene

Post-translational modifications for LPCAT1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for LPCAT1 Gene

Antibody Products

  • Abcam antibodies for LPCAT1

No data available for DME Specific Peptides for LPCAT1 Gene

Domains & Families for LPCAT1 Gene

Gene Families for LPCAT1 Gene

Suggested Antigen Peptide Sequences for LPCAT1 Gene

Graphical View of Domain Structure for InterPro Entry

Q8NF37

UniProtKB/Swiss-Prot:

PCAT1_HUMAN :
  • The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphocholine.
  • Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
Domain:
  • The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphocholine.
  • The di-lysine motif confers endoplasmic reticulum localization for type I membrane proteins.
Family:
  • Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
genes like me logo Genes that share domains with LPCAT1: view

Function for LPCAT1 Gene

Molecular function for LPCAT1 Gene

UniProtKB/Swiss-Prot CatalyticActivity:
Acyl-CoA + 1-acyl-sn-glycero-3-phosphocholine = CoA + 1,2-diacyl-sn-glycero-3-phosphocholine.
UniProtKB/Swiss-Prot CatalyticActivity:
Acetyl-CoA + 1-alkyl-sn-glycero-3-phosphocholine = CoA + 2-acetyl-1-alkyl-sn-glycero-3-phosphocholine.
UniProtKB/Swiss-Prot EnzymeRegulation:
Not activated by inflammatory stimulation. Inhibited by Cu(2+) and Fe(2+). Activity is not affected by Co(2+), Mg(2+) or Mn(2+) (By similarity).
UniProtKB/Swiss-Prot Function:
Possesses both acyltransferase and acetyltransferase activities (PubMed:16864775, PubMed:21498505). Activity is calcium-independent (By similarity). Mediates the conversion of 1-acyl-sn-glycero-3-phosphocholine (LPC) into phosphatidylcholine (PC) (PubMed:21498505). Displays a clear preference for saturated fatty acyl-CoAs, and 1-myristoyl or 1-palmitoyl LPC as acyl donors and acceptors, respectively (PubMed:16704971). May synthesize phosphatidylcholine in pulmonary surfactant, thereby playing a pivotal role in respiratory physiology (PubMed:16864775). Involved in the regulation of lipid droplet number and size (PubMed:25491198).

Enzyme Numbers (IUBMB) for LPCAT1 Gene

Phenotypes From GWAS Catalog for LPCAT1 Gene

Gene Ontology (GO) - Molecular Function for LPCAT1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity TAS --
GO:0005509 calcium ion binding IEA --
GO:0016740 transferase activity IEA --
GO:0016746 transferase activity, transferring acyl groups IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with LPCAT1: view
genes like me logo Genes that share phenotypes with LPCAT1: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

  • Applied Biological Materials Clones for LPCAT1
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for LPCAT1 Gene

Localization for LPCAT1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for LPCAT1 Gene

Endoplasmic reticulum membrane; Single-pass type II membrane protein. Golgi apparatus membrane; Single-pass type II membrane protein. Lipid droplet. Note=May adopt a monotopic topology when embedded in the lipid monolayer of the lipid droplet, with both termini exposed to the cytoplasm. {ECO:0000269 PubMed:21498505}.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for LPCAT1 gene
Compartment Confidence
plasma membrane 5
endoplasmic reticulum 5
golgi apparatus 5
lysosome 4
mitochondrion 2
nucleus 2
cytosol 2
peroxisome 1

Subcellular locations from the

Human Protein Atlas (HPA)
  • Endoplasmic reticulum (3)
  • Lipid droplets (3)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for LPCAT1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000139 Golgi membrane IEA --
GO:0005783 endoplasmic reticulum ISS --
GO:0005789 endoplasmic reticulum membrane TAS --
GO:0005794 Golgi apparatus ISS --
GO:0005811 lipid particle IDA,IEA 21498505
genes like me logo Genes that share ontologies with LPCAT1: view

Pathways & Interactions for LPCAT1 Gene

genes like me logo Genes that share pathways with LPCAT1: view

UniProtKB/Swiss-Prot Q8NF37-PCAT1_HUMAN

  • Pathway: Lipid metabolism; phospholipid metabolism.

Gene Ontology (GO) - Biological Process for LPCAT1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006629 lipid metabolic process IEA --
GO:0006644 phospholipid metabolic process IEA --
GO:0006654 phosphatidic acid biosynthetic process TAS --
GO:0006656 phosphatidylcholine biosynthetic process TAS --
GO:0008152 metabolic process IEA --
genes like me logo Genes that share ontologies with LPCAT1: view

No data available for SIGNOR curated interactions for LPCAT1 Gene

Drugs & Compounds for LPCAT1 Gene

(4) Drugs for LPCAT1 Gene - From: HMDB

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Hexanoyl-CoA Experimental Pharma 0
Propanoyl-CoA Experimental Pharma 0
calcium Nutra 0
Coenzyme A Nutra 0

(80) Additional Compounds for LPCAT1 Gene - From: HMDB

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
(2E)-Decenoyl-CoA
  • (E)-S-2-decenoate
  • (E)-S-2-decenoate CoA
  • (E)-S-2-decenoate Coenzyme A
  • (E)-S-2-decenoic acid
  • 2-trans-Decenoyl-CoA
10018-95-8
(2E)-Dodecenoyl-CoA
  • (2E)-Dodec-2-enoyl-CoA
  • (2E)-Dodec-2-enoyl-Coenzyme A
  • 2-trans-Dodecenoyl-CoA
  • 2-trans-Dodecenoyl-Coenzyme A
1066-12-2
(2E)-Hexadecenoyl-CoA
  • (2E)-Hexadecenoyl-CoA
  • (2E)-Hexadecenoyl-Coenzyme A
  • trans-2-Hexadecenoyl-CoA
  • trans-2-Hexadecenoyl-Coenzyme A
4460-95-1
(2E)-Octenoyl-CoA
  • (E)-S-2-octenoate
  • (E)-S-2-octenoate CoA
  • (E)-S-2-octenoate Coenzyme A
  • (E)-S-2-octenoic acid
  • 2,3-trans-Octenoyl coenzyme A
10018-94-7
(2E)-Tetradecenoyl-CoA
  • (2E)-Tetradecenoyl-CoA
  • (2E)-Tetradecenoyl-Coenzyme A
  • Trans-tetra-dec-2-enoyl-CoA
  • Trans-tetra-dec-2-enoyl-CoA.
  • Trans-tetra-dec-2-enoyl-Coenzyme A
38795-33-4
genes like me logo Genes that share compounds with LPCAT1: view

Transcripts for LPCAT1 Gene

Unigene Clusters for LPCAT1 Gene

Lysophosphatidylcholine acyltransferase 1:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

  • Applied Biological Materials Clones for LPCAT1
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for LPCAT1 Gene

No ASD Table

Relevant External Links for LPCAT1 Gene

GeneLoc Exon Structure for
LPCAT1
ECgene alternative splicing isoforms for
LPCAT1

Expression for LPCAT1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for LPCAT1 Gene

mRNA differential expression in normal tissues according to GTEx for LPCAT1 Gene

This gene is overexpressed in Whole Blood (x6.2) and Lung (x5.2).

Protein differential expression in normal tissues from HIPED for LPCAT1 Gene

This gene is overexpressed in Fetal Brain (9.8), Lung (8.6), NK cells (8.1), Peripheral blood mononuclear cells (7.2), and Bone (6.4).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for LPCAT1 Gene



Protein tissue co-expression partners for LPCAT1 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of LPCAT1 Gene:

LPCAT1

SOURCE GeneReport for Unigene cluster for LPCAT1 Gene:

Hs.368853

Evidence on tissue expression from TISSUES for LPCAT1 Gene

  • Nervous system(4.8)
  • Spleen(4.4)
  • Eye(4.2)
  • Lung(3.3)
genes like me logo Genes that share expression patterns with LPCAT1: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for LPCAT1 Gene

Orthologs for LPCAT1 Gene

This gene was present in the common ancestor of animals.

Orthologs for LPCAT1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia LPCAT1 33 34
  • 99.19 (n)
rat
(Rattus norvegicus)
Mammalia Lpcat1 33
  • 82.96 (n)
cow
(Bos Taurus)
Mammalia LPCAT1 33 34
  • 82.93 (n)
mouse
(Mus musculus)
Mammalia Lpcat1 33 16 34
  • 82.83 (n)
dog
(Canis familiaris)
Mammalia LPCAT1 33 34
  • 82.13 (n)
oppossum
(Monodelphis domestica)
Mammalia LPCAT1 34
  • 78 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia LPCAT1 34
  • 78 (a)
OneToOne
chicken
(Gallus gallus)
Aves LPCAT1 33 34
  • 69.88 (n)
lizard
(Anolis carolinensis)
Reptilia LPCAT1 34
  • 72 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia lpcat1 33
  • 69.08 (n)
Str.3303 33
zebrafish
(Danio rerio)
Actinopterygii lpcat1 33 34
  • 66.87 (n)
CABZ01078889.1 34
  • 50 (a)
OneToMany
fruit fly
(Drosophila melanogaster)
Insecta CG32699 33 34
  • 49.75 (n)
sea squirt
(Ciona intestinalis)
Ascidiacea Cin.7337 33
Species where no ortholog for LPCAT1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for LPCAT1 Gene

ENSEMBL:
Gene Tree for LPCAT1 (if available)
TreeFam:
Gene Tree for LPCAT1 (if available)

Paralogs for LPCAT1 Gene

Paralogs for LPCAT1 Gene

(3) SIMAP similar genes for LPCAT1 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with LPCAT1: view

Variants for LPCAT1 Gene

Sequence variations from dbSNP and Humsavar for LPCAT1 Gene

SNP ID Clin Chr 05 pos Sequence Context AA Info Type
rs587776361 untested 1,470,869(-) CGTCT(G/T)CCGGC reference, missense
rs1000035393 -- 1,471,631(+) AAGGG(A/C)AACCA intron-variant
rs1000075010 -- 1,493,038(+) GCCCC(A/G)TGAGC intron-variant
rs1000090341 -- 1,471,854(+) AGCAC(C/T)CAGAG intron-variant
rs1000109327 -- 1,501,946(+) TGACC(A/C)AGGCT intron-variant, reference, missense

Structural Variations from Database of Genomic Variants (DGV) for LPCAT1 Gene

Variant ID Type Subtype PubMed ID
dgv3022n106 CNV deletion 24896259
dgv3198e59 CNV duplication 20981092
dgv9536n54 CNV loss 21841781
dgv9541n54 CNV gain 21841781
esv2387011 CNV deletion 18987734
esv2462178 CNV deletion 19546169
esv27188 CNV loss 19812545
esv2729492 CNV deletion 23290073
esv2729493 CNV deletion 23290073
esv2729494 CNV deletion 23290073
esv2729495 CNV deletion 23290073
esv3186 CNV loss 18987735
esv3359326 CNV insertion 20981092
esv3395355 CNV duplication 20981092
esv3444246 CNV insertion 20981092
esv3565360 CNV deletion 23714750
esv3565361 CNV deletion 23714750
esv8815 CNV loss 19470904
esv994195 CNV insertion 20482838
nsv1073418 CNV deletion 25765185
nsv1073419 CNV deletion 25765185
nsv1112865 CNV deletion 24896259
nsv1114640 CNV deletion 24896259
nsv1117981 CNV deletion 24896259
nsv1133013 OTHER inversion 24896259
nsv1139363 CNV deletion 24896259
nsv1139364 CNV deletion 24896259
nsv1147234 OTHER inversion 26484159
nsv1149954 CNV deletion 26484159
nsv329642 CNV deletion 16902084
nsv461910 CNV loss 19166990
nsv596629 CNV gain 21841781
nsv596877 CNV loss 21841781
nsv596878 CNV loss 21841781
nsv596879 CNV gain 21841781
nsv596881 CNV gain+loss 21841781
nsv596882 CNV gain 21841781
nsv830187 CNV loss 17160897
nsv950629 CNV deletion 24416366

Variation tolerance for LPCAT1 Gene

Residual Variation Intolerance Score: 26.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 6.41; 77.12% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for LPCAT1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
LPCAT1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for LPCAT1 Gene

Disorders for LPCAT1 Gene

MalaCards: The human disease database

(1) MalaCards diseases for LPCAT1 Gene - From: GeneCards

Disorder Aliases PubMed IDs
retinitis pigmentosa
  • retinitis pigmentosa 1
- elite association - COSMIC cancer census association via MalaCards

Relevant External Links for LPCAT1

Genetic Association Database (GAD)
LPCAT1
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
LPCAT1
genes like me logo Genes that share disorders with LPCAT1: view

No data available for UniProtKB/Swiss-Prot and Genatlas for LPCAT1 Gene

Publications for LPCAT1 Gene

  1. Cloning and characterization of mouse lung-type acyl-CoA:lysophosphatidylcholine acyltransferase 1 (LPCAT1). Expression in alveolar type II cells and possible involvement in surfactant production. (PMID: 16704971) Nakanishi H … Shimizu T (The Journal of biological chemistry 2006) 2 3 4 60
  2. Human lysophosphatidylcholine acyltransferases 1 and 2 are located in lipid droplets where they catalyze the formation of phosphatidylcholine. (PMID: 21498505) Moessinger C … Thiele C (The Journal of biological chemistry 2011) 3 4 60
  3. Identification of a novel noninflammatory biosynthetic pathway of platelet-activating factor. (PMID: 18285344) Harayama T … Shimizu T (The Journal of biological chemistry 2008) 2 3 60
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 60
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 60

Products for LPCAT1 Gene

Sources for LPCAT1 Gene

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