Aliases for LPAR6 Gene
External Ids for LPAR6 Gene
Previous HGNC Symbols for LPAR6 Gene
Previous GeneCards Identifiers for LPAR6 Gene
The protein encoded by this gene belongs to the family of G-protein coupled receptors, that are preferentially activated by adenosine and uridine nucleotides. This gene aligns with an internal intron of the retinoblastoma susceptibility gene in the reverse orientation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2009]
GeneCards Summary for LPAR6 Gene
LPAR6 (Lysophosphatidic Acid Receptor 6) is a Protein Coding gene. Diseases associated with LPAR6 include hypotrichosis 8 and woolly hair, autosomal recessive. Among its related pathways are PI3K-Akt signaling pathway and Signaling by GPCR. GO annotations related to this gene include G-protein coupled receptor activity. An important paralog of this gene is PTAFR.
UniProtKB/Swiss-Prot for LPAR6 Gene
Binds to oleoyl-L-alpha-lysophosphatidic acid (LPA). Intracellular cAMP is involved in the receptor activation. Important for the maintenance of hair growth and texture.