Aliases for LPAR4 Gene
External Ids for LPAR4 Gene
Previous HGNC Symbols for LPAR4 Gene
Previous GeneCards Identifiers for LPAR4 Gene
This gene encodes a member of the lysophosphatidic acid receptor family. It may also be related to the P2Y receptors, a family of receptors that bind purine and pyrimidine nucleotides and are coupled to G proteins. The encoded protein may play a role in monocytic differentiation. [provided by RefSeq, Feb 2009]
GeneCards Summary for LPAR4 Gene
LPAR4 (Lysophosphatidic Acid Receptor 4) is a Protein Coding gene. Diseases associated with LPAR4 include Differentiated Thyroid Carcinoma. Among its related pathways are Nucleotide-like (purinergic) receptors and RET signaling. GO annotations related to this gene include G-protein coupled receptor activity and lipid binding. An important paralog of this gene is LPAR6.
UniProtKB/Swiss-Prot for LPAR4 Gene
Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. Transduces a signal by increasing the intracellular calcium ions and by stimulating adenylyl cyclase activity. The rank order of potency for agonists of this receptor is 1-oleoyl- > 1-stearoyl- > 1-palmitoyl- > 1-myristoyl- > 1-alkyl- > 1-alkenyl-LPA.