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LONRF3 Gene

protein-coding   GIFtS: 48
GCID: GC0XP118108

LON Peptidase N-Terminal Domain And Ring Finger 3

(Previous name: ring finger protein 127)
(Previous symbol: RNF127)
  Search for LONRF3
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
LON Peptidase N-Terminal Domain And Ring Finger 31 2
RING Finger Protein 1271 2 3
RNF1271 2 3
LON Peptidase N-Terminal Domain And RING Finger Protein 32

External Ids:    HGNC: 211521   Entrez Gene: 798362   Ensembl: ENSG000001755567   UniProtKB: Q496Y03   

Export aliases for LONRF3 gene to outside databases

Previous GC identifers: GC0XP117891 GC0XP117992 GC0XP107601


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for LONRF3 Gene:
The protein encoded by this gene contains a RING finger domain, a motif present in a variety of functionally
distinct proteins and known to be involved in protein-protein and protein-DNA interactions. Multiple
alternatively spliced transcript variants have been suggested, but their full length natures are not clear.
(provided by RefSeq, Jul 2008)

GeneCards Summary for LONRF3 Gene:
LONRF3 (LON peptidase N-terminal domain and ring finger 3) is a protein-coding gene. GO annotations related to this gene include ATP-dependent peptidase activity. An important paralog of this gene is LONRF2.




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000023.10  NT_011786.17  NC_018934.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the LONRF3 gene promoter:
         STAT1   Pax-5   STAT1beta   Lmo2   MIF-1   Tal-1beta   STAT1alpha   GATA-1   ITF-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidLONRF3 promoter sequence
   Search Chromatin IP Primers for LONRF3

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat LONRF3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: Xq24   Ensembl cytogenetic band:  Xq24   HGNC cytogenetic band: Xq24

LONRF3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
LONRF3 gene location

GeneLoc information about chromosome X         GeneLoc Exon Structure

GeneLoc location for GC0XP118108:  view genomic region     (about GC identifiers)

Start:
118,108,581 bp from pter      End:
118,152,318 bp from pter
Size:
43,738 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: LONF3_HUMAN, Q496Y0 (See protein sequence)
Recommended Name: LON peptidase N-terminal domain and RING finger protein 3  
Size: 759 amino acids; 84490 Da
Sequence caution: Sequence=BAB15419.1; Type=Erroneous initiation;
Secondary accessions: Q5JPN6 Q8NB00 Q9H647
Alternative splicing: 3 isoforms:  Q496Y0-1   Q496Y0-2   Q496Y0-3   

Explore the universe of human proteins at neXtProt for LONRF3: NX_Q496Y0

Explore proteomics data for LONRF3 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See LONRF3 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (3 alternative transcripts): 
    NP_001027026.1  NP_001276038.1  NP_079054.3  

    ENSEMBL proteins: 
     ENSP00000435426   ENSP00000360690   ENSP00000414519   ENSP00000307732   ENSP00000408894  

    LONRF3 Human Recombinant Protein Products:

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    Novus Biologicals LONRF3 Protein
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    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for LONRF3

     
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    Search eBioscience for ELISAs for LONRF3 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    RNF: RING-type (C3HC4) zinc fingers

    Selected InterPro protein domains (see all 9):
     IPR015947 PUA-like_domain
     IPR017907 Znf_RING_CS
     IPR011990 TPR-like_helical
     IPR001841 Znf_RING
     IPR003111 Pept_S16_N

    Graphical View of Domain Structure for InterPro Entry Q496Y0

    ProtoNet protein and cluster: Q496Y0

    UniProtKB/Swiss-Prot: LONF3_HUMAN, Q496Y0
    Similarity: Contains 1 Lon domain
    Similarity: Contains 2 RING-type zinc fingers
    Similarity: Contains 4 TPR repeats


    Find genes that share domains with LONRF3           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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         Gene Ontology (GO): 4 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004176ATP-dependent peptidase activity IEA--
    GO:0005515protein binding IPI--
    GO:0008270zinc ion binding IEA--
    GO:0046872metal ion binding ----
         
    Find genes that share ontologies with LONRF3           About GenesLikeMe


    Phenotypes:
         4 GenomeRNAi human phenotypes for LONRF3:
     Decreased cell number  Decreased viability of wild-ty  Increased gamma-H2AX phosphory  Synthetic lethal with Ras 

         1 MGI phenotypic allele for Lonrf3 (no phenotypes)

    Find genes that share phenotypes with LONRF3           About GenesLikeMe

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for LONRF3
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for LONRF3
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    miRNA
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    Selected qRT-PCR Assays for microRNAs that regulate LONRF3 (see all 10):
    hsa-miR-137 hsa-miR-92a hsa-miR-367 hsa-miR-25 hsa-miR-32 hsa-miR-103a hsa-miR-877* hsa-miR-363
    SwitchGear 3'UTR luciferase reporter plasmidLONRF3 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat LONRF3

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    GenScript: all cDNA clones in your preferred vector (see all 2): LONRF3 (NM_024778)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for LONRF3
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat LONRF3

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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus3
    cytosol2
    plasma membrane1

    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for LONRF3
    Interactions:

        Search GeneGlobe Interaction Network for LONRF3

    STRING Interaction Network Preview (showing 5 interactants - click image to see 6)

    Selected Interacting proteins for LONRF3 (Q496Y01, 3 ENSP000003606904) via UniProtKB, MINT, STRING, and/or I2D (see all 9)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    PHBP352321, 3EBI-2690768,EBI-354213 I2D: score=1 
    SMURF1Q9HCE73, ENSP000003546214I2D: score=2 STRING: ENSP00000354621
    RUVBL1ENSP000003182974STRING: ENSP00000318297
    RUVBL2ENSP000002214134STRING: ENSP00000221413
    DNAAF2ENSP000002982924STRING: ENSP00000298292
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006508proteolysis ----

    Find genes that share ontologies with LONRF3           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for LONRF3 (LONF3)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for LONRF3 gene (3 alternative transcripts): 
    NM_001031855.2  NM_001289109.1  NM_024778.5  

    Unigene Cluster for LONRF3:

    LON peptidase N-terminal domain and ring finger 3
    Hs.144266  [show with all ESTs]
    Unigene Representative Sequence: AK290198
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000481285(uc004eqw.3 uc004eqy.3) ENST00000371628 ENST00000439603
    ENST00000472173 ENST00000304778(uc004eqx.3) ENST00000422289(uc004eqz.3)

    miRNA
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    Block miRNA regulation of human, mouse, rat LONRF3 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate LONRF3 (see all 10):
    hsa-miR-137 hsa-miR-92a hsa-miR-367 hsa-miR-25 hsa-miR-32 hsa-miR-103a hsa-miR-877* hsa-miR-363
    SwitchGear 3'UTR luciferase reporter plasmidLONRF3 3' UTR sequence
    Inhib. RNA
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    GenScript: all cDNA clones in your preferred vector (see all 2): LONRF3 (NM_024778)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for LONRF3
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat LONRF3
    Primer
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    OriGene qSTAR qPCR primer pairs in human, mouse for LONRF3
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat LONRF3
      QuantiTect SYBR Green Assays in human, mouse, rat LONRF3
      QuantiFast Probe-based Assays in human, mouse, rat LONRF3

    Additional mRNA sequence: 

    AK026265.1 AK091777.1 AK097641.1 AK290198.1 BC098283.1 BC099847.1 BC100671.1 BC103491.1 

    4 DOTS entries:

    DT.121310897  DT.100014154  DT.427124  DT.99930615 

    23 AceView cDNA sequences:

    AI478294 NM_024778 AK091777 AX747177 CD370041 BX281995 CB134135 AI640750 
    AK097641 BE789669 BF000210 AA056722 AK026265 BG286456 AI215460 BF352076 
    AW015136 AI814601 BG997183 BE000485 T98138 BQ319784 AA056618 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for LONRF3    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11a · 11b ^ 12 ^ 13a · 13b
    SP1:                                                                    -                           
    SP2:              -                 -                                                               
    SP3:              -                 -                                   -                           
    SP4:              -           -     -                                   -                           


    ECgene alternative splicing isoforms for LONRF3

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    LONRF3 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CTGCATAACT
    LONRF3 Expression
    About this image


    LONRF3 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 3) fully expand
     
     Heart (Cardiovascular System)
             Cardiac Fibroblasts Myocardium
     
     Fibroblasts
             Cardiac Fibroblasts Myocardium
     
     Neural Tube (Nervous System)
             Telencephalon
    LONRF3 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    LONRF3 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.144266
        Custom PCR Arrays for LONRF3
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for LONRF3

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for LONRF3 gene from Selected species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Lonrf31 , 5 LON peptidase N-terminal domain and ring finger 31, 5 83.11(n)1
    81.55(a)1
      X (20.72 cM)5
    743651  NM_028894.11  NP_083170.11 
     363283535 
    chicken
    (Gallus gallus)
    Aves LONRF31 LON peptidase N-terminal domain and ring finger 3 66.87(n)
    64.76(a)
      422375  XM_420345.4  XP_420345.3 
    lizard
    (Anolis carolinensis)
    Reptilia LONRF36
    LON peptidase N-terminal domain and ring finger 3
    52(a)
    1 ↔ 1
    GL345114.1(1132-7901)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia lonrf31 LON peptidase N-terminal domain and ring finger 3 60.71(n)
    57.1(a)
      100486178  XM_002934542.2  XP_002934588.2 
    zebrafish
    (Danio rerio)
    Actinopterygii lonrf16
    LON peptidase N-terminal domain and ring finger 1
    36(a)
    many ↔ many
    14(35154723-35176681) ENSDARG00000075048
    fruit fly
    (Drosophila melanogaster)
    Insecta CG323696
    --
    19(a)
    1 → many
    3L(7770318-7802925)


    ENSEMBL Gene Tree for LONRF3 (if available)
    TreeFam Gene Tree for LONRF3 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for LONRF3 gene
    LONRF22  LONRF12  
    4 SIMAP similar genes for LONRF3 using alignment to 3 protein entries:     LONF3_HUMAN (see all proteins):
    LONRF1    LONRF2    TRIM5    TRIM39

    Find genes that share paralogs with LONRF3           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for LONRF3 (see all 730)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr X posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0359544
    A breast cancer sample4--see VAR_0359542 A G mis40--------
    rs1999941101,2
    C--107643420(+) TCTTT-/C/CTTT
            
    TTTTT
    2 -- int10--------
    rs1133326281,2
    C--107643421(+) TCTTTC/TTTTTT 2 -- int11Minor allele frequency- T:0.00NA 1
    rs347412141,2
    C--118102366(+) CTTCA-/T/TT  
            
    TTTTT
    2 -- us2k11CSA 2
    rs2021638911,2
    C--118102367(+) CTTCA-/TTTTTT 2 -- us2k10--------
    rs1823030391,2
    --118102635(+) AAAAAC/TGATGG 2 -- us2k10--------
    rs1858593871,2
    --118102797(+) CCCTGC/TCTCCC 2 -- us2k10--------
    rs1905183001,2
    --118102848(+) TTTGTG/TAGCTT 2 -- us2k10--------
    rs1823892091,2
    --118102897(+) GAGTGC/TGCAGT 2 -- us2k10--------
    rs1855302841,2
    C--118102949(+) CGAGGC/TCCCCT 2 -- us2k10--------

    HapMap Linkage Disequilibrium report for LONRF3 (118108581 - 118152318 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for LONRF3:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2740424CNV Deletion23290073

    Locus Specific Mutation Databases (LSDB): LONRF3

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing LONRF3
    DNA2.0 Custom Variant and Variant Library Synthesis for LONRF3

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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      --

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for LONRF3 gene integrated from 10 sources:
    (articles sorted by number of sources associating them with LONRF3)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The DNA sequence of the human X chromosome. (PubMed id 15772651)1, 2 Ross M.T.... Bentley D.R. (Nature 2005)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    4. A comprehensive resource of interacting protein regions for refining human transcription factor networks. (PubMed id 20195357)1 Miyamoto-Sato E....Yanagawa H. (PLoS ONE 2010)
    5. The consensus coding sequences of human breast and colorectal cancers. (PubMed id 16959974)2 Sjoeblom T.... Velculescu V.E. (Science 2006)
    6. High-throughput mapping of a dynamic signaling network in mammalian cells. (PubMed id 15761153)1 Barrios-Rodiles M....Wrana J.L. (Science 2005)
    7. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    8. Does this have a familiar RING? (PubMed id 8744354)1 Saurin A.J....Freemont P.S. (Trends Biochem. Sci. 1996)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 79836 HGNC: 21152 AceView: RNF127 Ensembl:ENSG00000175556 euGenes: HUgn79836
    ECgene: LONRF3 H-InvDB: LONRF3

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for LONRF3 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for LONRF3 gene:
    Search GeneIP for patents involving LONRF3

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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