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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

LOH12CR1 Gene

protein-coding   GIFtS: 46
GCID: GC12P012510

Loss Of Heterozygosity, 12, Chromosomal Region 1

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Loss Of Heterozygosity, 12, Chromosomal Region 11 2
LOH1CR122
Loss Of Heterozygosity 12 Chromosomal Region 1 Protein2

External Ids:    HGNC: 179501   Entrez Gene: 1184262   Ensembl: ENSG000001657147   UniProtKB: Q969J33   

Export aliases for LOH12CR1 gene to outside databases

Previous GC identifers: GC12P012238 GC12P012654 GC12P012410 GC12P012401 GC12P012276


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for LOH12CR1 Gene: 
LOH12CR1 (loss of heterozygosity, 12, chromosomal region 1) is a protein-coding gene. Diseases associated with LOH12CR1 include acute lymphoblastic leukemia, and lymphoblastic leukemia.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000012.11  NT_009714.17  NC_018923.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the LOH12CR1 gene promoter:
         Sp1   HTF   FOXD1   LCR-F1   RORalpha1   FOXJ2 (long isoform)   c-Myb   FOXJ2   ZID   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidLOH12CR1 promoter sequence
   Search SABiosciences Chromatin IP Primers for LOH12CR1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat LOH12CR1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12p12   Ensembl cytogenetic band:  12p13.2   HGNC cytogenetic band: 12p12

LOH12CR1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
LOH12CR1 gene location

GeneLoc information about chromosome 12         GeneLoc Exon Structure

GeneLoc location for GC12P012510:  view genomic region     (about GC identifiers)

Start:
12,510,013 bp from pter      End:
12,619,840 bp from pter
Size:
109,828 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: L12R1_HUMAN, Q969J3 (See protein sequence)
Recommended Name: Loss of heterozygosity 12 chromosomal region 1 protein  
Size: 196 amino acids; 22222 Da
Secondary accessions: Q96QS5
Alternative splicing: 2 isoforms:  Q969J3-1   Q969J3-2   

Explore the universe of human proteins at neXtProt for LOH12CR1: NX_Q969J3

Explore proteomics data for LOH12CR1 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q969J3

  • LOH12CR1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    LOH12CR1 Protein Expression
    REFSEQ proteins: NP_477517.1  
    ENSEMBL proteins: 
     ENSP00000443023   ENSP00000321546   ENSP00000298571  

    Human Recombinant Protein Products for LOH12CR1: 
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    Cloud-Clone Corp. Proteins for LOH12CR1 


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    Assay Products for LOH12CR1: 
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    Cloud-Clone Corp. ELISAs for LOH12CR1 
    Cloud-Clone Corp. CLIAs for LOH12CR1


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    1 InterPro protein domain:
     IPR018780 Tumour_suppressor_LOH1CR12

    Graphical View of Domain Structure for InterPro Entry Q969J3

    ProtoNet protein and cluster: Q969J3

    UniProtKB/Swiss-Prot: L12R1_HUMAN, Q969J3
    Similarity: Belongs to the LOH12CR1 family


    LOH12CR1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for LOH12CR1 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for LOH12CR1

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for LOH12CR1 
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    Inhib. RNA
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    Cell Line
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    Search LifeMap BioReagents cell lines for LOH12CR1
    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for LOH12CR1


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for LOH12CR1

    STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

    5/7 Interacting proteins for LOH12CR1 (Q969J32, 3 ENSP000003215464) via UniProtKB, MINT, STRING, and/or I2D (see all 7)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    PUF60Q9UHX12, 3, ENSP000003220164MINT-67107 I2D: score=4 STRING: ENSP00000322016
    MAD2L1Q132573I2D: score=5 
    UBE2L3P680363I2D: score=5 
    CSDE1O755343I2D: score=3 
    AIMP1Q129043I2D: score=2 
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for LOH12CR1 (L12R1)

    Search CenterWatch for drugs/clinical trials and news about LOH12CR1 / L12R1

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for LOH12CR1 gene: 
    NM_058169.3  

    Unigene Cluster for LOH12CR1:

    Loss of heterozygosity, 12, chromosomal region 1
    Hs.720779  [show with all ESTs]
    Unigene Representative Sequence: NM_058169
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000542728 ENST00000314565(uc001ral.2 uc009zhu.2) ENST00000543990
    ENST00000298571
    miRNA
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    1 QIAGEN miScript miRNA Assays for microRNA that regulate LOH12CR1:
    hsa-miR-590-3p
    SwitchGear 3'UTR luciferase reporter plasmidLOH12CR1 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for LOH12CR1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat LOH12CR1
    Clone
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    OriGene clones in human, mouse for LOH12CR1 (see all 8)
    OriGene ORF clones in mouse, rat for LOH12CR1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: LOH12CR1 (NM_058169)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for LOH12CR1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat LOH12CR1
    Sirion Biotech Customized lentivirus for stable overexpression of LOH12CR1 
                         Customized lentivirus expression plasmids for stable overexpression of LOH12CR1 
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for LOH12CR1
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat LOH12CR1
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat LOH12CR1

    Additional mRNA sequence: 

    AK075028.1 AY037865.1 AY037866.1 BC013668.1 

    4 DOTS entries:

    DT.91830101  DT.309934  DT.95287987  DT.121114129 

    24/78 AceView cDNA sequences (see all 78):

    AW504388 BQ690027 AY037866 AA256281 AY037865 CR626601 AW453026 BI755201 
    AA447954 BF346137 AW026232 CD635567 BF510597 BI561226 AI393641 BF059392 
    AW083807 BM828171 BI754349 CA306615 AL540987 BX477004 BF114690 BE464076 

    GeneLoc Exon Structure

    2 Alternative Splicing Database (ASD) splice patterns (SP) for LOH12CR1    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4a · 4b
    SP1:                                    
    SP2:              -                     


    ECgene alternative splicing isoforms for LOH12CR1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    LOH12CR1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AAAATCTGAC
    LOH12CR1 Expression
    About this image


    See LOH12CR1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for LOH12CR1

    SOURCE GeneReport for Unigene cluster: Hs.720779

    UniProtKB/Swiss-Prot: L12R1_HUMAN, Q969J3
    Tissue specificity: Widely expressed

        SABiosciences Custom PCR Arrays for LOH12CR1
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    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat LOH12CR1
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat LOH12CR1
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for LOH12CR1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for LOH12CR1 gene from 6/13 species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Loh12cr11 , 5 loss of heterozygosity, 12, chromosomal region 1 homolog more1, 5 87.91(n)1
    95.85(a)1
      6 (65.77 cM)5
    677741  NM_026371.31  NP_080647.21 
     1346409405 
    chicken
    (Gallus gallus)
    Aves LOH12CR11 loss of heterozygosity, 12, chromosomal region 1 81.09(n)
    89.89(a)
      426116  NM_001031357.1  NP_001026528.1 
    lizard
    (Anolis carolinensis)
    Reptilia LOH12CR16
    Uncharacterized protein
    90(a)
    1 ↔ 1
    5(83016132-83031263)
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.187152 Transcribed sequence with moderate similarity to protein more 77.72(n)    CK396627.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG118021 CG11802 47.95(n)
    36.36(a)
      32145  NM_132531.1  NP_572759.1 
    worm
    (Caenorhabditis elegans)
    Secernentea F59E12.116
    Protein F59E12.11
    20(a)
    1 ↔ 1
    II(5647983-5649470)


    ENSEMBL Gene Tree for LOH12CR1 (if available)
    TreeFam Gene Tree for LOH12CR1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/2641 SNPs in LOH12CR1 are shown (see all 2641)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 12 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs678381021,2
    C--12345313(+) TTTTC-/T/TTT 
     T
    /TTTTT
    TTTTT
    1 -- int11NA 2
    rs1863709071,2
    --12512009(+) GATATC/TTGGGG 1 -- int10--------
    rs1176697941,2
    F--12512031(+) TTCTTG/AGTCTA 1 -- int11Minor allele frequency- A:0.01EA 120
    rs752531971,2
    C--12512257(+) GCCCAA/GGAGTT 1 -- int10--------
    rs357328271,2
    C--12512299(+) TTTTT-/TGAGAC 1 -- int11Minor allele frequency- T:0.00NA 2
    rs1114708771,2
    C--12512328(+) AGTCTC/TACTGT 1 -- int11Minor allele frequency- T:0.50CSA 2
    rs1135686701,2
    C,F--12512443(+) GGGACT/ATGCCA 1 -- int11Minor allele frequency- A:0.50CSA 2
    rs1903515581,2
    --12512499(+) CCATGC/TTGGCC 1 -- int10--------
    rs1138395911,2
    C,F--12512503(+) GTTGGC/ACAGGC 1 -- int11Minor allele frequency- A:0.50CSA 2
    rs1828633371,2
    --12512531(+) CCTCAA/GGTGAT 1 -- int10--------

    HapMap Linkage Disequilibrium report for LOH12CR1 (12510013 - 12619840 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 10/24 variations for LOH12CR1 (see all 24):    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2662165CNV Deletion23128226
    esv2745568CNV Deletion23290073
    esv2421794CNV Deletion20811451
    dgv269e199CNV Deletion23128226
    esv2745567CNV Deletion23290073
    esv2673347CNV Deletion23128226
    esv271155CNV Insertion20981092
    esv274447CNV Insertion20981092
    nsv818893CNV Loss17921354
    dgv187n27CNV Loss19166990

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    3 diseases for LOH12CR1:    About MalaCards
    acute lymphoblastic leukemia    lymphoblastic leukemia    leukemia


    LOH12CR1 for disorders           About GeneDecksing

    Genetic Association Database (GAD): LOH12CR1

    Export disorders for LOH12CR1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for LOH12CR1 gene, integrated from 9 sources (see all 16):
    (articles sorted by number of sources associating them with LOH12CR1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. A detailed transcriptional map of the chromosome 12p12 tumour suppressor locus. (PubMed id 11896457)1, 2, 3 Montpetit A.... Sinnett D. (2002)
    2. Mutational and expression analysis of the chromosome 12p candidate tumor suppressor genes in pre-B acute lymphoblastic leukemia. (PubMed id 15284860)1, 3 Montpetit A.... Sinnett D. (2004)
    3. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (2012)
    4. Host-microbe interactions have shaped the genetic arch itecture of inflammatory bowel disease. (PubMed id 23128233)1 Jostins L....Cho J.H. (2012)
    5. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    6. System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)2 Rigbolt K.T....Blagoev B. (2011)
    7. Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PubMed id 20068231)2 Olsen J.V....Mann M. (2010)
    8. Identification of FBXO25-interacting proteins using an integrated proteomics approach. (PubMed id 20473970)1 Teixeira F.R.... Gomes M.D. (2010)
    9. Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach. (PubMed id 19413330)2 Gauci S....Mohammed S. (2009)
    10. Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. (PubMed id 19690332)2 Mayya V.... Han D.K. (2009)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 118426 HGNC: 17950 AceView: LOH12CR1 Ensembl:ENSG00000165714 euGenes: HUgn118426
    ECgene: LOH12CR1 H-InvDB: LOH12CR1

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for LOH12CR1 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for LOH12CR1 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for LOH12CR1 gene:
    Search GeneIP for patents involving LOH12CR1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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     Proteins for LOH12CR1
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     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat LOH12CR1
     inGenious Targeting Laboratory - Custom generated mouse model solutions for LOH12CR1
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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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