LOC93432 Gene
protein-coding GIFtS: 29
GCID: GC07P142664
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LOC93432
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Aliases
for LOC93432 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Maltase-Glucoamylase (Alpha-Glucosidase) Pseudogene2 | | EC 3.2.1.-3 | | EC 3.2.1.208 |
Export aliases for LOC93432 gene to outside databasesPrevious GC identifers: GC07P140082 GC07P141141 GC07U900904 GC07P141219 GC07P141264 GC07P141458 GC07P142151 GC07P142169 GC07P141153 GC07P142325 GC07P142396 GC07P142442 GC07P142575 |
Summaries
for LOC93432 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for LOC93432 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000007.13 NC_018918.1 NT_007914.15 NT_079596.2
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the LOC93432 gene promoter:
Pbx1a AML1a Pax-2 CUTL1 Pax-2a Ik-2 FOXJ2 (long isoform) STAT3 FOXJ2
Other transcription factors
Search SABiosciences Chromatin IP Primers for LOC93432
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat LOC93432 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 7q34 Ensembl cytogenetic band: 7q34 LOC93432 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 7 GeneLoc Exon Structure GeneLoc location for GC07P142664: view genomic region
(about GC identifiers)
Start:
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141,811,549 bp from pter |
End:
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141,921,088 bp from pter |
Size:
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109,540 bases |
Orientation:
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plus strand |
1 alternative location:
| Chr7+,CRA_TCAG 141,149,748-141,181,982 |
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Proteins
for LOC93432 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: MGAL1_HUMAN, Q6ZN80 (See
protein sequence)Recommended Name: Putative maltase-glucoamylase-like protein FLJ16351 Size: 646 amino acids; 73930 DaUniProtKB/Swiss-Prot: MGAL2_HUMAN, Q2M2H8 (See
protein sequence) Recommended Name: Putative inactive maltase-glucoamylase-like protein LOC93432 Size: 482 amino acids; 55146 Da
Subcellular location: Membrane; Single-pass type II membrane protein (Potential)
Caution: Although it belongs to the glycosyl hydrolase 31 family, it is truncated at the C-terminus and lacks theactive site residues, thus suggesting it lacks glycosidase activity
Secondary accessions: A4D2I3Explore the universe of human proteins at neXtProt for LOC93432: NX_Q2M2H8
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q2M2H8
2 DME Specific Peptides for LOC93432 (Q6ZN80)
LOC93432 Protein expression data from MOPED and PaxDb: About this image 
ENSEMBL proteins: ENSP00000447431 ENSP00000420449 ENSP00000448551
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
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| GO:0016021 | integral to membrane |
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LOC93432 for ontologies About GeneDecksing
LOC93432 Antibody Products:
Assay Products for LOC93432: |
Protein
Domains /
Families
for LOC93432 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
LOC93432 for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q6ZN80Graphical View of Domain Structure for InterPro Entry Q2M2H8ProtoNet protein and cluster: Q6ZN80 1 Blocks protein family: IPB000322 Glycoside hydrolase
UniProtKB/Swiss-Prot: MGAL1_HUMAN, Q6ZN80Similarity: Belongs to the glycosyl hydrolase 31 familyUniProtKB/Swiss-Prot: MGAL2_HUMAN, Q2M2H8Similarity: Belongs to the glycosyl hydrolase 31 familySimilarity: Contains 1 P-type (trefoil) domain |
Function
for LOC93432 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
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Enzyme Numbers (IUBMB): EC 3.2.1.-1 EC 3.2.1.202
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for LOC93432 |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0004553 | hydrolase activity, hydrolyzing O-glycosyl compounds |
-- | -- | | GO:0030246 | carbohydrate binding |
-- | -- |
LOC93432 for ontologies About GeneDecksing
|
Pathways & Interactions
for LOC93432 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
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Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for LOC93432
Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
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| GO:0005975 | carbohydrate metabolic process |
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LOC93432 for ontologies About GeneDecksing
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Drugs & Compounds
for LOC93432 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for LOC93432
Search CenterWatch for drugs/clinical trials and news about LOC93432 / MGAL2 
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Transcripts
for LOC93432 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for LOC93432 gene: NM_001008748.2 Unigene Cluster for LOC93432: Maltase-glucoamylase (alpha-glucosidase) pseudogene Hs.647098 Unigene Representative Sequence: AK0006454 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000550469(uc003vwz.3) ENST00000477922 ENST00000496337(uc003vxa.2)
ENST00000550494
Primer
Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for LOC93432
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat LOC93432 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat LOC93432 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat LOC93432 |
Additional cDNA sequence: AK000645.1 BC111973.1 BC111975.1 NR_003715.1 1 DOTS entry: DT.101961042 1 AceView cDNA sequence: AK000645
GeneLoc Exon Structure
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Expression
for LOC93432 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| LOC93432 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: ATCATCTGGA
About this image
See LOC93432 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for LOC93432
SOURCE GeneReport for Unigene cluster: Hs.647098
SABiosciences Custom PCR Arrays for LOC93432
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for LOC93432
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat LOC93432 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat LOC93432 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat LOC93432 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for LOC93432 |
Orthologs
for LOC93432 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for LOC93432 gene from 5/17 species (see all 17) About this table
ENSEMBL Gene Tree for LOC93432 (if available)
TreeFam Gene Tree for LOC93432 (if available) |
Paralogs
for LOC93432 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for LOC93432 gene
- MGAM2 SI2 GAA2 GANC2 GANAB2
LOC93432 for paralogs About GeneDecksing
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Genomic Variants
for LOC93432 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 7 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for LOC93432 (141811549 - 141921088 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 3 variations for LOC93432
3 CNVs: 48010 3706 7607 | SABiosciences Cancer Mutation PCR Assays |
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Disorders
/ Diseases
for LOC93432 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for LOC93432 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for LOC93432 gene integrated from 9 sources:
(articles sorted by number of sources associating them with LOC93432) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Human chromosome 7: DNA sequence and biology. (PubMed id 12690205)1, 2 Scherer S.W.... Tsui L.-C. (2003)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
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External Searches for LOC93432 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
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Genome Databases showing LOC93432 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
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Other Databases showing LOC93432 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing LOC93432 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
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About This Section
| Patent Information for LOC93432 gene:
Search GeneIP for patents involving LOC93432
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for LOC93432 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
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|  | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat LOC93432 | | | Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing LOC93432 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat LOC93432 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat LOC93432 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat LOC93432 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat LOC93432 |
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 | | | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for LOC93432 |
|  |  |  | | | | Search ThermoFisher Antibodies for LOC93432 |
| | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat LOC93432 |
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