LOC728741 Gene
protein-coding GIFtS: 24
GCID: GC16M028353 (predicted)
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LOC728741
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Aliases
for LOC728741 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
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| Aliases |
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| Uncharacterized LOC7287412 |
Export aliases for LOC728741 gene to outside databasesPrevious GC identifers: GC16P028670 GC16P028763 |
Summaries
for LOC728741 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
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-- |
Genomic Views
for LOC728741 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000016.9 NT_010393.16 NC_018927.1
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the LOC728741 gene promoter:
ER-alpha AML1a Sp1 SREBP-1c Lmo2 SREBP-1b SREBP-1a E2F-1 E2F HOXA5
Other transcription factors
Search SABiosciences Chromatin IP Primers for LOC728741
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat LOC728741 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 16p11.2 Ensembl cytogenetic band: 16p11.2 LOC728741 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 16 GeneLoc Exon Structure GeneLoc location for GC16M028353: view genomic region
(about GC identifiers)
Start:
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28,353,838 bp from pter |
End:
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28,374,829 bp from pter |
Size:
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20,992 bases |
Orientation:
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minus strand |
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Proteins
for LOC728741 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
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UniProtKB/TrEMBL: B2RXF8 (See
protein sequence)Recommended Name: LOC728741 protein Size: 455 amino acids; 52491 DaUniProtKB/TrEMBL: E9PJ23 (See
protein sequence) Recommended Name: Protein LOC728741 Size: 425 amino acids; 49162 Da
Caution: The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered aspreliminary dataUniProtKB/TrEMBL: E9PS57 (See
protein sequence) Recommended Name: Protein LOC728741 Size: 407 amino acids; 47243 Da
Caution: The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered aspreliminary dataLOC728741 Protein expression data from MOPED and PaxDb: --
ENSEMBL proteins: ENSP00000435924 ENSP00000431871
Human Recombinant Protein Products for LOC728741:
LOC728741 Antibody Products:
Assay Products for LOC728741: |
Protein
Domains /
Families
for LOC728741 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
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LOC728741 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry B2RXF8Graphical View of Domain Structure for InterPro Entry E9PJ23Graphical View of Domain Structure for InterPro Entry E9PS57ProtoNet protein and cluster: B2RXF8 |
Function
for LOC728741 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
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Animal Models:
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Pathways & Interactions
for LOC728741 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
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Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for LOC728741
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Drugs & Compounds
for LOC728741 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
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 Browse Tocris compounds for LOC728741
Search CenterWatch for drugs/clinical trials and news about LOC728741 
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Transcripts
for LOC728741 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
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Unigene Cluster for LOC728741: Uncharacterized LOC728741 Hs.726467 [show with all ESTs]Unigene Representative Sequence: BC1578362 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000533640(uc010vcq.2 uc002dpe.2) ENST00000532254(uc010vcr.2)
Additional cDNA sequence: BC144439.1 BC157836.1 XM_003118718.1 15 DOTS entries: DT.100680980 DT.100773284 DT.120697824 DT.92028187 DT.95232081 DT.100868004 DT.120681573 DT.120695084 DT.120698214 DT.120726521 DT.121097446 DT.91663280 DT.95191520 DT.95298396 DT.97860083
GeneLoc Exon Structure
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Expression
for LOC728741 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| LOC728741 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
Genevestigator expression for LOC728741
SOURCE GeneReport for Unigene cluster: Hs.726467
SABiosciences Custom PCR Arrays for LOC728741
Primer
Products: |  | Browse OriGene genome-wide validated SYBR primer pairs
Browse OriGene validated miRNA SYBR primer pairs
| | | Search SABiosciences RT2 qPCR
Primer Assays in human, mouse, rat LOC728741 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat LOC728741 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat LOC728741 |
Orthologs
for LOC728741 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
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ENSEMBL Gene Tree for LOC728741 (if available)
TreeFam Gene Tree for LOC728741 (if available) |
Paralogs
for LOC728741 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for LOC728741 gene
- LOC1005076071 2 LOC728734 NPIPL21 2 LOC4403532 LOC7288882 ENSG000001980642 ENSG000002149402 NPIPL12
- 61E3.42 PKD1P12 LOC6427992 LOC1002883322 NPIP2 ENSG000002149672 ENSG000002262322 NPIPL32
- LOC7299782 LOC6427782 LOC7301532 ENSG000001969932 LOC6130372
15 SIMAP similar genes for LOC728741 using alignment to 3 protein entries: B2RXF8_HUMAN (see all proteins):A-575C2.4 NPIPL2 A-761H5.4 LOC728734 NPIPL1 61E3.4
NPIPL3 LOC728888 NPIPP1 NPIP Nbla00537 LOC642778
LOC339047 A-589H1.1 PKD1P1
LOC728741 for paralogs About GeneDecksing
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Genomic Variants
for LOC728741 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
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| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 16 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
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HapMap Linkage Disequilibrium report for LOC728741 (28353838 - 28374829 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for LOC728741: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing LOC728741 |
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Disorders
/ Diseases
for LOC728741 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
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Publications
for LOC728741 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
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PubMed article for LOC728741 gene integrated from 9 sources:
(articles sorted by number of sources associating them with LOC728741) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
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External Searches for LOC728741 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
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Genome Databases showing LOC728741 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
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Other Databases showing LOC728741 gene
(According to HUGE)
About This Section
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Specialized Databases showing LOC728741 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
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About This Section
| Patent Information for LOC728741 gene:
Search GeneIP for patents involving LOC728741
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for LOC728741 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
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|  | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat LOC728741 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing LOC728741 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat LOC728741 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat LOC728741 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat LOC728741 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat LOC728741 |
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