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Aliases for LOC100133315 Gene

Aliases for LOC100133315 Gene

  • Transient Receptor Potential Cation Channel, Subfamily C, Member 2-Like 3
  • TrpC2-Like Protein 4

External Ids for LOC100133315 Gene

Previous GeneCards Identifiers for LOC100133315 Gene

  • GC11U900991
  • GC11M071254
  • GC11M071576

Summaries for LOC100133315 Gene

GeneCards Summary for LOC100133315 Gene

LOC100133315 (Transient Receptor Potential Cation Channel, Subfamily C, Member 2-Like) is a Pseudogene. GO annotations related to this gene include damaged DNA binding. An important paralog of this gene is ENSG00000268361.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for LOC100133315 Gene

Genomics for LOC100133315 Gene

Regulatory Elements for LOC100133315 Gene

Genomic Location for LOC100133315 Gene

Start:
71,865,509 bp from pter
End:
71,928,654 bp from pter
Size:
63,146 bases
Orientation:
Minus strand

Genomic View for LOC100133315 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for LOC100133315 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for LOC100133315 Gene

Proteins for LOC100133315 Gene

  • Protein details for LOC100133315 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6ZNB5-TRC2L_HUMAN
    Recommended name:
    Putative short transient receptor potential channel 2-like protein
    Protein Accession:
    Q6ZNB5
    Secondary Accessions:

    Protein attributes for LOC100133315 Gene

    Size:
    142 amino acids
    Molecular mass:
    15763 Da
    Quaternary structure:
    No Data Available

neXtProt entry for LOC100133315 Gene

Proteomics data for LOC100133315 Gene at MOPED

Post-translational modifications for LOC100133315 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for LOC100133315 Gene

Domains for LOC100133315 Gene

Protein Domains for LOC100133315 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

Q6ZNB5

UniProtKB/Swiss-Prot:

TRC2L_HUMAN :
  • Q6ZNB5
Family:
  • Belongs to the transient receptor (TC 1.A.4) family. STrpC subfamily.
genes like me logo Genes that share domains with LOC100133315: view

No data available for Gene Families and Suggested Antigen Peptide Sequences for LOC100133315 Gene

Function for LOC100133315 Gene

Gene Ontology (GO) - Molecular Function for LOC100133315 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003684 damaged DNA binding IEA --
GO:0005515 protein binding --
GO:0005516 calmodulin binding --
GO:0015279 store-operated calcium channel activity --
GO:0019992 diacylglycerol binding --
genes like me logo Genes that share ontologies with LOC100133315: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for LOC100133315 Gene

Localization for LOC100133315 Gene

Gene Ontology (GO) - Cellular Components for LOC100133315 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000139 Golgi membrane --
GO:0005634 nucleus IEA --
GO:0005635 nuclear envelope --
GO:0005789 endoplasmic reticulum membrane --
GO:0005886 plasma membrane --
genes like me logo Genes that share ontologies with LOC100133315: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from COMPARTMENTS for LOC100133315 Gene

Pathways for LOC100133315 Gene

SuperPathways for LOC100133315 Gene

No Data Available

Interacting Proteins for LOC100133315 Gene

Gene Ontology (GO) - Biological Process for LOC100133315 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000012 single strand break repair IEA --
GO:0002121 inter-male aggressive behavior --
GO:0002124 territorial aggressive behavior --
GO:0006284 base-excision repair --
GO:0006816 calcium ion transport --
genes like me logo Genes that share ontologies with LOC100133315: view

No data available for Pathways by source for LOC100133315 Gene

Transcripts for LOC100133315 Gene

mRNA/cDNA for LOC100133315 Gene

(2) Additional mRNA sequences :
(9) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for LOC100133315 Gene

Transient receptor potential cation channel, subfamily C, member 2-like:
Representative Sequences:

miRNA Products

  • QIAGEN qRT-PCR Assays for microRNAs that regulate LOC100133315
    • Block miRNA regulation of LOC100133315 using miScript Target Protectors

    Inhibitory RNA Products

    • Predesigned siRNA for gene silencing in human,mouse,rat for LOC100133315

    Primer Products

    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat

    Flow Cytometry Products

    Alternative Splicing Database (ASD) splice patterns (SP) for LOC100133315 Gene

    No ASD Table

    Relevant External Links for LOC100133315 Gene

    GeneLoc Exon Structure for
    LOC100133315

    Expression for LOC100133315 Gene

    mRNA expression in normal human tissues for LOC100133315 Gene

    SOURCE GeneReport for Unigene cluster for LOC100133315 Gene Hs.150324

    genes like me logo Genes that share expressions with LOC100133315: view

    In Situ Assay Products

    No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for LOC100133315 Gene

    Orthologs for LOC100133315 Gene

    This gene was present in the common ancestor of animals.

    Orthologs for LOC100133315 Gene

    Organism Taxonomy Gene Similarity Type Details
    chimpanzee
    (Pan troglodytes)
    Mammalia -- 36
    • 96 (a)
    OneToOne
    platypus
    (Ornithorhynchus anatinus)
    Mammalia -- 36
    • 37 (a)
    OneToOne
    chicken
    (Gallus gallus)
    Aves -- 36
    • 26 (a)
    OneToOne
    zebrafish
    (Danio rerio)
    Actinopterygii zgc:110224 36
    • 20 (a)
    OneToOne
    fruit fly
    (Drosophila melanogaster)
    Insecta XRCC1 36
    • 7 (a)
    OneToMany
    sea squirt
    (Ciona savignyi)
    Ascidiacea -- 36
    • 10 (a)
    OneToMany
    Species with no ortholog for LOC100133315:
    • A. gosspyii yeast (Ashbya gossypii)
    • Actinobacteria (Mycobacterium tuberculosis)
    • African clawed frog (Xenopus laevis)
    • African malaria mosquito (Anopheles gambiae)
    • Alicante grape (Vitis vinifera)
    • alpha proteobacteria (Wolbachia pipientis)
    • amoeba (Dictyostelium discoideum)
    • Archea (Pyrococcus horikoshii)
    • baker's yeast (Saccharomyces cerevisiae)
    • barley (Hordeum vulgare)
    • beta proteobacteria (Neisseria meningitidis)
    • bread mold (Neurospora crassa)
    • Chromalveolata (Phytophthora infestans)
    • common water flea (Daphnia pulex)
    • corn (Zea mays)
    • cow (Bos Taurus)
    • dog (Canis familiaris)
    • E. coli (Escherichia coli)
    • filamentous fungi (Aspergillus nidulans)
    • Firmicute bacteria (Streptococcus pneumoniae)
    • fission yeast (Schizosaccharomyces pombe)
    • green algae (Chlamydomonas reinhardtii)
    • honey bee (Apis mellifera)
    • K. lactis yeast (Kluyveromyces lactis)
    • lizard (Anolis carolinensis)
    • loblloly pine (Pinus taeda)
    • malaria parasite (Plasmodium falciparum)
    • medicago trunc (Medicago Truncatula)
    • moss (Physcomitrella patens)
    • mouse (Mus musculus)
    • oppossum (Monodelphis domestica)
    • orangutan (Pongo pygmaeus)
    • pig (Sus scrofa)
    • rainbow trout (Oncorhynchus mykiss)
    • rat (Rattus norvegicus)
    • rice (Oryza sativa)
    • rice blast fungus (Magnaporthe grisea)
    • schistosome parasite (Schistosoma mansoni)
    • sea anemone (Nematostella vectensis)
    • sea urchin (Strongylocentrotus purpuratus)
    • sorghum (Sorghum bicolor)
    • soybean (Glycine max)
    • stem rust fungus (Puccinia graminis)
    • sugarcane (Saccharum officinarum)
    • thale cress (Arabidopsis thaliana)
    • tomato (Lycopersicon esculentum)
    • toxoplasmosis (Toxoplasma gondii)
    • Trichoplax (Trichoplax adhaerens)
    • tropical clawed frog (Silurana tropicalis)
    • wheat (Triticum aestivum)
    • worm (Caenorhabditis elegans)

    Evolution for LOC100133315 Gene

    ENSEMBL:
    Gene Tree for LOC100133315 (if available)
    TreeFam:
    Gene Tree for LOC100133315 (if available)

    Paralogs for LOC100133315 Gene

    Paralogs for LOC100133315 Gene

    genes like me logo Genes that share paralogs with LOC100133315: view

    Variants for LOC100133315 Gene

    Sequence variations from dbSNP and Humsavar for LOC100133315 Gene

    SNP ID Clin Chr 11 pos Sequence Context AA Info Type MAF
    rs474231 -- 71,876,001(+) GCCTG(A/G)GTGAC intron-variant
    rs475759 -- 71,867,946(-) aaaca(A/G)gttat intron-variant
    rs475959 -- 71,894,286(+) GTGTG(A/G)TGGCG intron-variant
    rs479487 -- 71,867,517(-) AACCA(C/T)ATGTA intron-variant
    rs481300 -- 71,867,337(-) TCCCA(C/T)AAAGA intron-variant

    Structural Variations from Database of Genomic Variants (DGV) for LOC100133315 Gene

    Variant ID Type Subtype PubMed ID
    dgv223e199 CNV Deletion 23128226
    esv2744758 CNV Deletion 23290073
    dgv1219n71 CNV Gain 21882294
    dgv396e1 CNV Complex 17122850
    nsv428262 CNV Gain+Loss 18775914
    esv25167 CNV Gain 19812545
    nsv509428 CNV Insertion 20534489
    esv273257 CNV Insertion 20981092
    esv2744760 CNV Deletion 23290073
    nsv383 CNV Insertion 18451855

    Relevant External Links for LOC100133315 Gene

    HapMap Linkage Disequilibrium report
    LOC100133315

    No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for LOC100133315 Gene

    Disorders for LOC100133315 Gene

    Relevant External Links for LOC100133315

    Genetic Association Database (GAD)
    LOC100133315
    Human Genome Epidemiology (HuGE) Navigator
    LOC100133315
    genes like me logo Genes that share disorders with LOC100133315: view

    No data available for UniProtKB/Swiss-Prot for LOC100133315 Gene

    Publications for LOC100133315 Gene

    1. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3 48
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 4
    3. TRPC2: molecular biology and functional importance. (PMID: 17217050) Yildirim E. … Birnbaumer L. (Handb Exp Pharmacol 2007) 3
    4. Characterization of TRPC2, an essential genetic component of VNS chemoreception, provides insights into the evolution of pheromonal olfaction in secondary-adapted marine mammals. (PMID: 20142439) Yu L. … Zhang Y.P. (Mol. Biol. Evol. 2010) 3

    Products for LOC100133315 Gene

    • QIAGEN qRT-PCR Assays for microRNAs that regulate LOC100133315
      • QuantiTect SYBR Green Assays in human,mouse,rat
      • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
      • QuantiFast Probe-based Assays in human,mouse,rat
      • Predesigned siRNA for gene silencing in human,mouse,rat for LOC100133315
      • Block miRNA regulation of LOC100133315 using miScript Target Protectors

      Sources for LOC100133315 Gene

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