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Aliases for LOC100133315 Gene

Aliases for LOC100133315 Gene

  • Transient Receptor Potential Cation Channel, Subfamily C, Member 2-Like 3
  • Putative Short Transient Receptor Potential Channel 2-Like Protein 5
  • TrpC2-Like Protein 4
  • RP11-849H4.2 5

External Ids for LOC100133315 Gene

Previous GeneCards Identifiers for LOC100133315 Gene

  • GC11U900991
  • GC11M071254
  • GC11M071576

Summaries for LOC100133315 Gene

GeneCards Summary for LOC100133315 Gene

LOC100133315 (Transient Receptor Potential Cation Channel, Subfamily C, Member 2-Like) is a Pseudogene. GO annotations related to this gene include calmodulin binding and store-operated calcium channel activity. An important paralog of this gene is ENSG00000268361.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for LOC100133315 Gene

Genomics for LOC100133315 Gene

Regulatory Elements for LOC100133315 Gene

Enhancers for LOC100133315 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around LOC100133315 on UCSC Golden Path with GeneCards custom track

Promoters for LOC100133315 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around LOC100133315 on UCSC Golden Path with GeneCards custom track

Genomic Location for LOC100133315 Gene

71,865,509 bp from pter
71,928,654 bp from pter
63,146 bases
Minus strand

Genomic View for LOC100133315 Gene

Genes around LOC100133315 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
LOC100133315 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for LOC100133315 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for LOC100133315 Gene

Proteins for LOC100133315 Gene

  • Protein details for LOC100133315 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Putative short transient receptor potential channel 2-like protein
    Protein Accession:

    Protein attributes for LOC100133315 Gene

    142 amino acids
    Molecular mass:
    15763 Da
    Quaternary structure:
    No Data Available

neXtProt entry for LOC100133315 Gene

Proteomics data for LOC100133315 Gene at MOPED

Post-translational modifications for LOC100133315 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for LOC100133315 Gene

No data available for DME Specific Peptides for LOC100133315 Gene

Domains & Families for LOC100133315 Gene

Protein Domains for LOC100133315 Gene


Graphical View of Domain Structure for InterPro Entry



  • Belongs to the transient receptor (TC 1.A.4) family. STrpC subfamily.
  • Belongs to the transient receptor (TC 1.A.4) family. STrpC subfamily.
genes like me logo Genes that share domains with LOC100133315: view

No data available for Gene Families and Suggested Antigen Peptide Sequences for LOC100133315 Gene

Function for LOC100133315 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for LOC100133315 Gene

Localization for LOC100133315 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for LOC100133315 Gene

Pathways & Interactions for LOC100133315 Gene

SuperPathways for LOC100133315 Gene

No Data Available

Interacting Proteins for LOC100133315 Gene

Gene Ontology (GO) - Biological Process for LOC100133315 Gene


No data available for Pathways by source and SIGNOR curated interactions for LOC100133315 Gene

Drugs & Compounds for LOC100133315 Gene

No Compound Related Data Available

Transcripts for LOC100133315 Gene

mRNA/cDNA for LOC100133315 Gene

(2) Additional mRNA sequences :
(9) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for LOC100133315 Gene

Transient receptor potential cation channel, subfamily C, member 2-like:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for LOC100133315 Gene

No ASD Table

Relevant External Links for LOC100133315 Gene

GeneLoc Exon Structure for

Expression for LOC100133315 Gene

mRNA expression in normal human tissues for LOC100133315 Gene

SOURCE GeneReport for Unigene cluster for LOC100133315 Gene Hs.150324

genes like me logo Genes that share expression patterns with LOC100133315: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for LOC100133315 Gene

Orthologs for LOC100133315 Gene

This gene was present in the common ancestor of animals.

Orthologs for LOC100133315 Gene

Organism Taxonomy Gene Similarity Type Details
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 37 (a)
(Pan troglodytes)
Mammalia -- 36
  • 96 (a)
(Gallus gallus)
Aves -- 36
  • 26 (a)
(Danio rerio)
Actinopterygii zgc:110224 36
  • 20 (a)
fruit fly
(Drosophila melanogaster)
Insecta XRCC1 36
  • 7 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 10 (a)
Species with no ortholog for LOC100133315:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for LOC100133315 Gene

Gene Tree for LOC100133315 (if available)
Gene Tree for LOC100133315 (if available)

Paralogs for LOC100133315 Gene

Paralogs for LOC100133315 Gene

genes like me logo Genes that share paralogs with LOC100133315: view

Variants for LOC100133315 Gene

Sequence variations from dbSNP and Humsavar for LOC100133315 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type
rs518959 -- 71,890,059(+) GTTCC(A/G)GAAAG intron-variant
rs519098 -- 71,890,106(+) ATTGT(C/T)TTCCC intron-variant
rs526054 -- 71,893,681(+) TGACA(C/T)CGGTT intron-variant
rs529522 -- 71,869,516(-) atgca(C/G)acgta intron-variant
rs529567 -- 71,869,491(-) ctatt(C/T)gcaat intron-variant

Structural Variations from Database of Genomic Variants (DGV) for LOC100133315 Gene

Variant ID Type Subtype PubMed ID
dgv223e199 CNV Deletion 23128226
esv2744758 CNV Deletion 23290073
dgv1219n71 CNV Gain 21882294
dgv396e1 CNV Complex 17122850
nsv428262 CNV Gain+Loss 18775914
esv25167 CNV Gain 19812545
nsv509428 CNV Insertion 20534489
esv273257 CNV Insertion 20981092
esv2744760 CNV Deletion 23290073
nsv383 CNV Insertion 18451855

Variation tolerance for LOC100133315 Gene

Gene Damage Index Score: 4.49; 64.41% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for LOC100133315 Gene

Disorders for LOC100133315 Gene

Relevant External Links for LOC100133315

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator

No disorders were found for LOC100133315 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for LOC100133315 Gene

Publications for LOC100133315 Gene

  1. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3 48 67
  2. Characterization of TRPC2, an essential genetic component of VNS chemoreception, provides insights into the evolution of pheromonal olfaction in secondary-adapted marine mammals. (PMID: 20142439) Yu L. … Zhang Y.P. (Mol. Biol. Evol. 2010) 3
  3. TRPC2: molecular biology and functional importance. (PMID: 17217050) Yildirim E. … Birnbaumer L. (Handb Exp Pharmacol 2007) 3

Products for LOC100133315 Gene

Sources for LOC100133315 Gene