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Aliases for LOC100133315 Gene

Aliases for LOC100133315 Gene

  • Transient Receptor Potential Cation Channel, Subfamily C, Member 2-Like 3
  • TrpC2-Like Protein 4

External Ids for LOC100133315 Gene

Previous GeneCards Identifiers for LOC100133315 Gene

  • GC11U900991
  • GC11M071254
  • GC11M071576

Summaries for LOC100133315 Gene

GeneCards Summary for LOC100133315 Gene

LOC100133315 (Transient Receptor Potential Cation Channel, Subfamily C, Member 2-Like) is a Pseudogene. GO annotations related to this gene include calmodulin binding and store-operated calcium channel activity. An important paralog of this gene is ENSG00000268361.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for LOC100133315 Gene

Genomics for LOC100133315 Gene

Regulatory Elements for LOC100133315 Gene

Genomic Location for LOC100133315 Gene

Chromosome:
11
Start:
71,865,509 bp from pter
End:
71,928,654 bp from pter
Size:
63,146 bases
Orientation:
Minus strand

Genomic View for LOC100133315 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
GeneLoc Logo Gene Density

RefSeq DNA sequence for LOC100133315 Gene

Proteins for LOC100133315 Gene

  • Protein details for LOC100133315 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6ZNB5-TRC2L_HUMAN
    Recommended name:
    Putative short transient receptor potential channel 2-like protein
    Protein Accession:
    Q6ZNB5

    Protein attributes for LOC100133315 Gene

    Size:
    142 amino acids
    Molecular mass:
    15763 Da
    Quaternary structure:
    No Data Available

neXtProt entry for LOC100133315 Gene

Proteomics data for LOC100133315 Gene at MOPED

Post-translational modifications for LOC100133315 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for LOC100133315 Gene

No data available for DME Specific Peptides for LOC100133315 Gene

Domains & Families for LOC100133315 Gene

Protein Domains for LOC100133315 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

Q6ZNB5

UniProtKB/Swiss-Prot:

TRC2L_HUMAN :
  • Belongs to the transient receptor (TC 1.A.4) family. STrpC subfamily.
Family:
  • Belongs to the transient receptor (TC 1.A.4) family. STrpC subfamily.
genes like me logo Genes that share domains with LOC100133315: view

No data available for Gene Families and Suggested Antigen Peptide Sequences for LOC100133315 Gene

Function for LOC100133315 Gene

Gene Ontology (GO) - Molecular Function for LOC100133315 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003684 damaged DNA binding IEA --
genes like me logo Genes that share ontologies with LOC100133315: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for LOC100133315 Gene

Localization for LOC100133315 Gene

Gene Ontology (GO) - Cellular Components for LOC100133315 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with LOC100133315: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from COMPARTMENTS for LOC100133315 Gene

Pathways & Interactions for LOC100133315 Gene

SuperPathways for LOC100133315 Gene

No Data Available

Interacting Proteins for LOC100133315 Gene

Gene Ontology (GO) - Biological Process for LOC100133315 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000012 single strand break repair IEA --
GO:0006284 base-excision repair --
genes like me logo Genes that share ontologies with LOC100133315: view

No data available for Pathways by source and SIGNOR curated interactions for LOC100133315 Gene

Drugs & Compounds for LOC100133315 Gene

No Compound Related Data Available

Transcripts for LOC100133315 Gene

mRNA/cDNA for LOC100133315 Gene

(2) Additional mRNA sequences :
(9) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for LOC100133315 Gene

Transient receptor potential cation channel, subfamily C, member 2-like:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for LOC100133315 Gene

No ASD Table

Relevant External Links for LOC100133315 Gene

GeneLoc Exon Structure for
LOC100133315

Expression for LOC100133315 Gene

mRNA expression in normal human tissues for LOC100133315 Gene

SOURCE GeneReport for Unigene cluster for LOC100133315 Gene Hs.150324

genes like me logo Genes that share expression patterns with LOC100133315: view

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for LOC100133315 Gene

Orthologs for LOC100133315 Gene

This gene was present in the common ancestor of animals.

Orthologs for LOC100133315 Gene

Organism Taxonomy Gene Similarity Type Details
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 37 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia -- 36
  • 96 (a)
OneToOne
chicken
(Gallus gallus)
Aves -- 36
  • 26 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii zgc:110224 36
  • 20 (a)
OneToOne
fruit fly
(Drosophila melanogaster)
Insecta XRCC1 36
  • 7 (a)
OneToMany
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 10 (a)
OneToMany
Species with no ortholog for LOC100133315:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for LOC100133315 Gene

ENSEMBL:
Gene Tree for LOC100133315 (if available)
TreeFam:
Gene Tree for LOC100133315 (if available)

Paralogs for LOC100133315 Gene

Paralogs for LOC100133315 Gene

genes like me logo Genes that share paralogs with LOC100133315: view

Variants for LOC100133315 Gene

Sequence variations from dbSNP and Humsavar for LOC100133315 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type MAF
rs474231 -- 71,876,001(+) GCCTG(A/G)GTGAC intron-variant
rs475759 -- 71,867,946(-) aaaca(A/G)gttat intron-variant
rs475959 -- 71,894,286(+) GTGTG(A/G)TGGCG intron-variant
rs479487 -- 71,867,517(-) AACCA(C/T)ATGTA intron-variant
rs481300 -- 71,867,337(-) TCCCA(C/T)AAAGA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for LOC100133315 Gene

Variant ID Type Subtype PubMed ID
dgv223e199 CNV Deletion 23128226
esv2744758 CNV Deletion 23290073
dgv1219n71 CNV Gain 21882294
dgv396e1 CNV Complex 17122850
nsv428262 CNV Gain+Loss 18775914
esv25167 CNV Gain 19812545
nsv509428 CNV Insertion 20534489
esv273257 CNV Insertion 20981092
esv2744760 CNV Deletion 23290073
nsv383 CNV Insertion 18451855

Relevant External Links for LOC100133315 Gene

HapMap Linkage Disequilibrium report
LOC100133315

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for LOC100133315 Gene

Disorders for LOC100133315 Gene

Relevant External Links for LOC100133315

Genetic Association Database (GAD)
LOC100133315
Human Genome Epidemiology (HuGE) Navigator
LOC100133315
genes like me logo Genes that share disorders with LOC100133315: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for LOC100133315 Gene

Publications for LOC100133315 Gene

  1. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 67
  2. Characterization of TRPC2, an essential genetic component of VNS chemoreception, provides insights into the evolution of pheromonal olfaction in secondary-adapted marine mammals. (PMID: 20142439) Yu L. … Zhang Y.P. (Mol. Biol. Evol. 2010) 67
  3. TRPC2: molecular biology and functional importance. (PMID: 17217050) Yildirim E. … Birnbaumer L. (Handb Exp Pharmacol 2007) 67
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 67

Products for LOC100133315 Gene

Sources for LOC100133315 Gene

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