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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

LNX2 Gene

protein-coding   GIFtS: 51
GCID: GC13M028120

Ligand Of Numb-Protein X 2

(Previous name: PDZ domain containing ring finger 1)
(Previous symbol: PDZRN1)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Ligand Of Numb-Protein X 21 2
PDZRN11 2 3 5
PDZ Domain Containing Ring Finger 11 2
Numb-Binding Protein 22 3
PDZ Domain-Containing RING Finger Protein 12 3
Ligand Of Numb Protein X 22

External Ids:    HGNC: 204211   Entrez Gene: 2224842   Ensembl: ENSG000001395177   OMIM: 6097335   UniProtKB: Q8N4483   

Export aliases for LNX2 gene to outside databases

Previous GC identifers: GC13U990083 GC13M025918 GC13M027018 GC13M008941


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for LNX2 Gene: 
LNX2 (ligand of numb-protein X 2) is a protein-coding gene. Diseases associated with LNX2 include q fever, and endocarditis. GO annotations related to this gene include PDZ domain binding and zinc ion binding. An important paralog of this gene is PARD3B.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000013.10  NT_024524.14  NC_018924.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the LNX2 gene promoter:
         HFH-3   FOXI1   AhR   Pbx1a   Pax-5   Nkx2-2   Lmo2   Msx-1   Arnt   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidLNX2 promoter sequence
   Search SABiosciences Chromatin IP Primers for LNX2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat LNX2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 13q12.2   Ensembl cytogenetic band:  13q12.2   HGNC cytogenetic band: 13q12.2

LNX2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
LNX2 gene location

GeneLoc information about chromosome 13         GeneLoc Exon Structure

GeneLoc location for GC13M028120:  view genomic region     (about GC identifiers)

Start:
28,120,050 bp from pter      End:
28,194,720 bp from pter
Size:
74,671 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: LNX2_HUMAN, Q8N448 (See protein sequence)
Recommended Name: Ligand of Numb protein X 2  
Size: 690 amino acids; 76004 Da
Subunit: Interacts with the phosphotyrosine interaction domain of NUMB (By similarity)
Sequence caution: Sequence=BAD18754.1; Type=Erroneous initiation;
1 PDB 3D structure from and Proteopedia for LNX2:
2VWR (3D)    
Secondary accessions: Q5W0P0 Q6ZMH2 Q96SH4

Explore the universe of human proteins at neXtProt for LNX2: NX_Q8N448

Explore proteomics data for LNX2 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q8N448

  • LNX2 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    LNX2 Protein Expression
    REFSEQ proteins: NP_699202.1  
    ENSEMBL proteins: 
     ENSP00000325929  

    Human Recombinant Protein Products for LNX2: 
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    Novus Biologicals LNX2 Protein
    Novus Biologicals LNX2 Lysate
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    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for LNX2 


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    Cloud-Clone Corp. ELISAs for LNX2 
    Cloud-Clone Corp. CLIAs for LNX2


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    RNF: RING-type (C3HC4) zinc fingers

    4 InterPro protein domains:
     IPR017907 Znf_RING_CS
     IPR001841 Znf_RING
     IPR001478 PDZ
     IPR013083 Znf_RING/FYVE/PHD

    Graphical View of Domain Structure for InterPro Entry Q8N448

    ProtoNet protein and cluster: Q8N448

    2 Blocks protein domains:
    IPB001478 PDZ/DHR/GLGF domain
    IPB001841 Zn-finger


    UniProtKB/Swiss-Prot: LNX2_HUMAN, Q8N448
    Domain: The NPXY motif is required for the interaction with the PID domain of NUMB. It is however not sufficient
    Similarity: Contains 4 PDZ (DHR) domains
    Similarity: Contains 1 RING-type zinc finger


    LNX2 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

         Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI--
    GO:0008270zinc ion binding IEA--
    GO:0030165PDZ domain binding IEA--
    GO:0046872metal ion binding ----
         
    LNX2 for ontologies           About GeneDecksing


    Phenotypes:
         3 GenomeRNAi human phenotypes for LNX2:
     Decreased Tat-dependent transc  Decreased p24 protein expressi  Increased gamma-H2AX phosphory 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for LNX2 
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    miRNA
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    8/31 QIAGEN miScript miRNA Assays for microRNAs that regulate LNX2 (see all 31):
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    SwitchGear 3'UTR luciferase reporter plasmidLNX2 3' UTR sequence
    Inhib. RNA
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for LNX2


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for LNX2

    STRING Interaction Network Preview (showing 5 interactants - click image to see 11)

    5/24 Interacting proteins for LNX2 (Q8N4481, 2, 3 ENSP000003259294) via UniProtKB, MINT, STRING, and/or I2D (see all 24)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    E4F1Q66K892, 3, ENSP000003017274MINT-8207368 I2D: score=1 STRING: ENSP00000301727
    LNX1Q8TBB13, ENSP000002639254I2D: score=3 STRING: ENSP00000263925
    UBE2IP632793, ENSP000003248974I2D: score=2 STRING: ENSP00000324897
    NUMBP497573, ENSP000003471694I2D: score=3 STRING: ENSP00000347169
    CD8AP017323, ENSP000002836354I2D: score=1 STRING: ENSP00000283635
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0051260protein homooligomerization IEA--

    LNX2 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for LNX2

    Search CenterWatch for drugs/clinical trials and news about LNX2

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for LNX2 gene: 
    NM_153371.3  

    Unigene Cluster for LNX2:

    Ligand of numb-protein X 2
    Hs.132359  [show with all ESTs]
    Unigene Representative Sequence: NM_153371
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000316334(uc001url.4 uc001urm.1)
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat LNX2
    8/31 QIAGEN miScript miRNA Assays for microRNAs that regulate LNX2 (see all 31):
    hsa-miR-498 hsa-miR-328 hsa-miR-181c hsa-miR-548v hsa-miR-1271 hsa-miR-1297 hsa-miR-10b* hsa-miR-124
    SwitchGear 3'UTR luciferase reporter plasmidLNX2 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
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    Clone
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    GenScript: all cDNA clones in your preferred vector: LNX2 (NM_153371)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for LNX2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat LNX2
    Sirion Biotech Customized lentivirus for stable overexpression of LNX2 
                         Customized lentivirus expression plasmids for stable overexpression of LNX2 
    Primer
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    OriGene qPCR primer pairs and template standards for LNX2
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat LNX2
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat LNX2

    Additional mRNA sequence: 

    AK022995.1 AK095319.1 AK313394.1 BC036755.2 

    6 DOTS entries:

    DT.210268  DT.100022102  DT.91698497  DT.120775986  DT.120776034  DT.120776045 

    24/65 AceView cDNA sequences (see all 65):

    AA630753 BM971327 AI783640 BQ017483 NM_153371 CK429277 Z38767 BQ109475 
    AI700820 AK095319 BC036755 CA432775 BU686432 BM556292 BQ721926 BE265067 
    BX281727 CN479234 BM800852 BU662330 AK022995 AI814120 BG928554 BE264978 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    LNX2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GAACAAGTTT
    LNX2 Expression
    About this image


    See LNX2 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for LNX2

    SOURCE GeneReport for Unigene cluster: Hs.132359
        SABiosciences Custom PCR Arrays for LNX2
    Primer
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for LNX2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for LNX2 gene from 7/15 species (see all 15)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Lnx21 , 5 ligand of numb-protein X 21, 5 80.9(n)1
    90.52(a)1
      5 (86.69 cM)5
    1408871  NM_080795.41  NP_542985.41 
     1470166555 
    chicken
    (Gallus gallus)
    Aves LNX21 ligand of numb-protein X 2 76.95(n)
    84.21(a)
      418928  XM_417122.3  XP_417122.2 
    lizard
    (Anolis carolinensis)
    Reptilia LNX26
    Uncharacterized protein
    84(a)
    1 ↔ 1
    GL343306.1(1221541-1324831)
    African clawed frog
    (Xenopus laevis)
    Amphibia BJ032220.12   -- 73.44(n)    BJ032220.1 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.111172 Transcribed sequence with weak similarity to protein more 74.54(n)    BG307401.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Patj6
    CG158036
    --
    4(a)
    3(a)
    many ↔ many
    many ↔ many
    3L(1798803-1802184)
    3R(14159008-14186699)
    worm
    (Caenorhabditis elegans)
    Secernentea mpz-16
    Protein MPZ-1, isoform d
    4(a)
    1 → many
    II(10738986-10775061)


    ENSEMBL Gene Tree for LNX2 (if available)
    TreeFam Gene Tree for LNX2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for LNX2 gene
    PARD3B2  INADL2  PARD32  MPDZ2  LNX12  
    1 SIMAP similar gene for LNX2 using alignment to 1 protein entry:     LNX2_HUMAN:
    LNX1

    LNX2 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1548 SNPs in LNX2 are shown (see all 1548)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 13 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs2009783801,2
    --28119553(+) GTTAC-/AAATTT 1 -- ds50010--------
    rs1154584991,2
    C,F--28119555(+) TACAAA/TTTTTT 1 -- ds50011Minor allele frequency- T:0.08WA 118
    rs1841021991,2
    --28119609(+) TGGTAA/GCTCAC 1 -- ds50010--------
    rs1417569261,2
    --28119674(+) CAGTTC/TGAGAC 1 -- ds50010--------
    rs1113388241,2
    F--28119817(+) TTGCAA/GTGAGC 1 -- ds50011Minor allele frequency- G:0.00CSA 1
    rs1138222291,2
    C,F--28119940(+) CTGAGG/ATTTCA 1 -- ds50011Minor allele frequency- A:0.50CSA 2
    rs1495268771,2
    --28119942(+) GAGGTC/TTCATG 1 -- ds50010--------
    rs1441243151,2
    C--28119951(+) TGCTCA/GGTGCT 1 -- ds50010--------
    rs766540241,2
    C,F--28119973(+) AAGGAC/TAGTGG 1 -- ds50012Minor allele frequency- T:0.06NA 122
    rs10465241,2
    C,H--28120170(-) TAGTTC/TTGATA 1 -- ut314Minor allele frequency- T:0.00MN NS NA 368

    HapMap Linkage Disequilibrium report for LNX2 (28120050 - 28194720 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for LNX2:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2048214CNV Deletion18987734
    nsv899952CNV Loss21882294


    Human Gene Mutation Database (HGMD): LNX2
    SABiosciences Cancer Mutation PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 609733    OMIM disorders: --

    2 diseases for LNX2:    About MalaCards
    q fever    endocarditis

    1 disease from the University of Copenhagen DISEASES database for LNX2:
    Q fever

    LNX2 for disorders           About GeneDecksing

    Genetic Association Database (GAD): LNX2
    Human Genome Epidemiology (HuGE) Navigator: LNX2 (1 document)

    Export disorders for LNX2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for LNX2 gene, integrated from 9 sources (see all 21):
    (articles sorted by number of sources associating them with LNX2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The DNA sequence and analysis of human chromosome 13. (PubMed id 15057823)1, 2 Dunham A.... Ross M.T. (2004)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    4. Genetic amplification of the NOTCH modulator LNX2 upre gulates the WNT/b-catenin pathway in colorectal cancer. (PubMed id 23319804)1 Camps J....Ried T. (2013)
    5. Systematic analysis of dimeric E3-RING interactions re veals increased combinatorial complexity in human ubiquitination networks. (PubMed id 22493164)1 Woodsmith J....Sanderson C.M. (2012)
    6. Protein interactions of the transcription factor Hoxa1 . (PubMed id 23088713)1 Lambert B....Rezsohazy R. (2012)
    7. Proteomics strategy to identify substrates of LNX, a P DZ domain-containing E3 ubiquitin ligase. (PubMed id 22889411)1 Guo Z....Gao Y. (2012)
    8. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (2012)
    9. The ligands of Numb proteins X1 and X2 are specific ma rkers for chronic Q fever. (PubMed id 22066909)1 Mehraj V....Ghigo E. (2012)
    10. Direct and indirect control of mitogen-activated prote in kinase pathway-associated components, BRAP/IMP E3 ubiquitin ligase and CRAF/R AF1 kinase, by the deubiquitylating enzyme USP15. (PubMed id 23105109)1 Hayes S.D....Urbe S. (2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
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    NCBI Bookshelf
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 222484 HGNC: 20421 AceView: LNX2 Ensembl:ENSG00000139517 euGenes: HUgn222484
    ECgene: LNX2 H-InvDB: LNX2

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for LNX2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for LNX2 gene:
    Search GeneIP for patents involving LNX2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

     
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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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