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LMO2 Gene

protein-coding   GIFtS: 65

GC11M033836
LIM domain only 2 (rhombotin-like 1)
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
(Previous symbol: RBTNL1)
Services    

Aliases &
Descriptions
for LMO2

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc , and/or 7Ensembl, 8miRBase)
About This Section
Aliases
RBTN2 1, 2, 3
RBTNL1 2, 3, 5
RHOM2 1, 2, 3, 5
TTG2 1, 2, 3, 5
Descriptions
Cysteine-rich protein TTG-2 3
LIM domain only 2 2
LIM domain only 2 (rhombotin-like 1) 2
LIM domain only protein 2 3
T-cell translocation gene 2 2
T-cell translocation protein 2 3
rhombotin 2 2
rhombotin-like 1 2
External Ids
HGNC: 66421
Entrez Gene: 40052
UniProtKB: P257913
Ensembl: ENSG000001353637
Search outside databases for aliases for LMO2 gene

Previous GC identifers: GC11M035411 GC11M034557 GC11M033919 GC11M033844

Summaries
for LMO2

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

 EntrezGene summary for LMO2:
LMO2 encodes a cysteine-rich, two LIM-domain protein that is required for yolk sac erythropoiesis.
The LMO2 protein has a central and crucial role in hematopoietic development and is highly
conserved. The LMO2 transcription start site is located approximately 25 kb downstream from the
11p13 T-cell translocation cluster (11p13 ttc), where a number T-cell acute lymphoblastic
leukemia-specific translocations occur. Alternative splicing results in multiple transcript
variants encoding different isoforms.

UniProtKB/Swiss-Prot: RBTN2_HUMAN, P25791
Function: Acts with TAL1/SCL to regulate red blood cell development. Also acts with LDB1 to
maintain erythroid precursors in an immature state

Gene Wiki entry for LMO2

Genomic Location
for LMO2

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

 Genomic View:
UCSC Golden Path with GeneCards custom track

 Transcription factor binding sites upstream to the LMO2 gene  

Entrez Gene cytogenetic band: 11p13   Ensembl cytogenetic band:  11p13   HGNC cytogenetic band: 11p13

LMO2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 11         GeneLoc Exon Structure

GeneLoc location for GC11M033836:     (about GC identifiers)

Start:
 33,836,698 bp from pter
End:
 33,870,412 bp from pter
Size:
 33,715 bases
Orientation:
 minus strand
RefSeq DNA sequence:
NC_000011.8  NT_009237.17  

Proteins
for LMO2

(According to 1UniProtKB, and/or Ensembl, Phosphorylation sites according to 2Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

 UniProtKB/Swiss-Prot: RBTN2_HUMAN, P25791 (See protein sequence)
Recommended Name: Rhombotin-2  
Size: 158 amino acids; 18358 Da
Subunit: Interacts via its LIM domains with ELF2 and LBD1. Also interacts with basic
helix-loop-helix protein TAL1/SCL and can assemble in a complex with LMO2 and TAL1/SCL (By
similarity). Interacts with BEX2 and KDM5A
Subcellular location: Nucleus (Potential)
Secondary accessions: Q9HD58
Alternative splicing: 2 isoforms:  P25791-1   P25791-2   

Post-translational modifications:

  • View phosphorylation sites using PhosphoSite2


    • REFSEQ proteins (3 alternative transcripts): 
    NP_001135787.1  NP_001135788.1  NP_005565.2  


    ENSEMBL proteins: 
    ENSP00000257818 ENSP00000379175 


    Human Recombinant Proteins 
    Browse Drug Discovery Central at Invitrogen for human recombinant proteins
    Browse Purified and Recombinant Proteins at Millipore
    Browse Human Recombinant Proteins at Sigma-Aldrich  
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Recombinant Proteins from Abcam (LMO2)
    Human Recombinant Proteins from Abnova (LMO2)
                  OriGene Purified Recombinant Human Protein: LMO2 

    1 Gene Ontology (GO) cellular component term (links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634 nucleus IEA--
    About this table

    Antibodies for LMO2: 
    Browse Antibodies Central at Invitrogen
    Millipore Mono- and Polyclonal Antibodies for the study of LMO2
    Sigma-Aldrich Antibodies for LMO2
    R&D Systems Antibodies for LMO2
    Antibodies from Abcam (LMO2), each with their AbpromiseSM
    Monoclonal and Polyclonal Antibodies from Abnova (LMO2)
    Novus Biologicals Antibodies for LMO2

    Assays for LMO2: 
    Browse Invitrogen for biochemical assays
    Browse Kits and Assays available from Millipore
    Browse R&D Systems for biochemical assays
    Browse biochemical assays available from Enzo Life Sciences

    Protein Domains/
    Families
    for LMO2

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    1 InterPro domain/family:
     IPR001781 Znf_LIM


       GeneDecks  LMO2 for the domains selected above  
    About GeneDecksing

    Graphical View of Domain Structure for InterPro Entry P25791

    ProtoNet protein and cluster: P25791

    1 Blocks protein family: IPB001781 Zn-binding protein

    UniProtKB/Swiss-Prot: RBTN2_HUMAN, P25791
    Domain: The second LIM zinc-binding domain interacts with KDM5A
    Similarity: Contains 2 LIM zinc-binding domains

    Gene Function
    for LMO2

    (According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
    shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
    RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
    About This Section
    Inhib.
    RNA:    		Invitrogen RNAi Products for gene knock-down (LMO2)
    Browse for Gene Knock-down Tools from Millipore
    Abnova Chimera RNAi Products for Gene knock-down (LMO2)
                   OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 3): NM_001142315

                  Applied Biosystems Silencer® siRNAs for LMO2

                  Sigma-Aldrich siRNA for LMO2  
                         Sigma-Aldrich shRNA for LMO2  
                         Explore Sigma-Aldrich super-pooled esiRNAs  

    Clones:Invitrogen Clones for LMO2
    Browse Clones for the Expression of Recombinant Proteins Available from Millipore
                   OriGene GFP tagged cDNA clones in CMV expression vector (see all 3): NM_001142315
                                     Myc/DDK tagged cDNA clones in CMV expression vector (see all 3): NM_001142315
                                     untagged cDNA clones in CMV expression vector (see all 3): NM_001142315 

    Primers: Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers
                  OriGene genome-wide validated SYBR primer pairs: NM_005574

    UniProtKB/Swiss-Prot: RBTN2_HUMAN, P25791
    Function: Acts with TAL1/SCL to regulate red blood cell development. Also acts with LDB1 to
    maintain erythroid precursors in an immature state

    Genatlas biochemistry entry for LMO2:
    LIM domain only 2,rhombotin 2,involved in association with LMO1 (and others),in the formation of
    multimeric DNA-binding complex for the generation of hematopoietic lineages and angiogenesis (in
    mice)

    13 MGI mutant phenotypes (inferred from 4 alleles) (MGI details for Lmo2):

    cellularembryogenesisgrowth/sizehematopoietic system
    immune systemlethality-prenatal/perinatallife span-post-weaning/agingliver/biliary systemnervous system
    renal/urinary systemskin/coat/nailstumorigenesis

    3 Gene Ontology (GO) molecular function terms (links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515 protein binding ISS--
    GO:0008270 zinc ion binding IEA--
    GO:0046872 metal ion binding IEA--
    About this table

    Pathways & Interactions
    for LMO2

    (Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
    Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to 1UniProtKB, 2MINT, and/or 3STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
    About This Section


     Gene Network CentralTM Interacting Genes and Proteins Network for  LMO2 


    5/38 Interacting proteins for LMO2 (ENSP000002578183 P257912) via UniProtKB, MINT, and/or STRING (see all 38 )
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MLLT4P551962STRING (score=.966) MINT-16706 MINT-16707
    RLIMQ9NVW22STRING (score=.967) MINT-17113
    DAZAP2Q150382MINT-67456
    EHMT2Q96KQ72MINT-67674
    ENSG00000206376Q96KQ72MINT-67674
    About this table

    1 Gene Ontology (GO) biological process term (links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007275 multicellular organismal development TAS1923511
    About this table

    Drugs & Compounds
    for LMO2

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
    About This Section

    Browse drugs & compounds from Enzo Life Sciences
    Browse Small Molecules at Sigma-Aldrich

    Browse Tocris compounds for LMO2
    2 Novoseek chemical compound relationships for LMO2 gene
    Compound   Score   Articles   PubMed IDs for Articles with Shared Sentences (# sentences)
    tal 2 84.50 3 7957052 (2), 14975618 (1)
    zinc 6.45 2 9209374 (1), 7544155 (1)
    About this table


    Transcripts
    for LMO2

    (GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView,
    non coding RNAs according to RNAdb,
    ESTs according to GeneTide,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from Invitrogen, Millipore, and/or Abnova,
    siRNAs from Applied Biosystems, Sigma-Aldrich,
    shRNA from Sigma-Aldrich, OriGene,
    Tagged/untagged cDNA clones from OriGene,
    Expression Assays from Applied Biosystems)
    About This Section
    Inhib.
    RNA:    		Invitrogen RNAi Products for gene knock-down (LMO2)
    Browse for Gene Knock-down Tools from Millipore
    Abnova Chimera RNAi Products for Gene knock-down (LMO2)
                   OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 3): NM_001142315

                  Sigma-Aldrich siRNA for LMO2  
                         Sigma-Aldrich shRNA for LMO2  
                         Explore Sigma-Aldrich super-pooled esiRNAs  

    Applied Biosystems Silencer® siRNAs: 

    NM_001142315  NM_001142316  NM_005574  

    REFSEQ mRNAs for LMO2 gene (3 alternative transcripts): 

    NM_001142315.1   NM_001142316.1   NM_005574.3   

    Applied Biosystems TaqMan ® Gene Expression Assays: 

    NM_001142315  NM_001142316  NM_005574  

                   OriGene GFP tagged cDNA clones in CMV expression vector (see all 3): NM_001142315
                                     Myc/DDK tagged cDNA clones in CMV expression vector (see all 3): NM_001142315
                                     untagged cDNA clones in CMV expression vector (see all 3): NM_001142315 

    Additional cDNA sequence: 

    AF257211.1 AK127915.1 BC034041.1 BC035607.1 BC042426.1 BC073973.1 CR604507.1 CR625714.1 
    X61118.1 

    9 DOTS entries:

    DT.454509  DT.100775807  DT.100707202  DT.444566  DT.95188348  DT.95161059  DT.97808158  DT.87008922 
    DT.87015072 

    24/151 AceView cDNA sequences (see all 151 ):

    BF340978 AI247832 AW235360 AA280651 AA742325 CR614368 CR604507 CR625714 
    AI302050 AI052253 AA447059 AA907895 AL534189 H90810 BX373857 AI291194 
    AA443672 AA987902 AW172398 AI128847 BU676547 AW665040 AA464544 AI359899 

    highest scoring ESTs for LMO2:

    AA056578 AA258970 AA261902 AA280651 AA282029 AA363913 AA418542 AA418607 AA443672 AA447059 

    Unigene Cluster for LMO2:

    LIM domain only 2 (rhombotin-like 1)
    Hs.34560  [show with all ESTs]
    Unigene Representative Sequence: X61118


    GeneLoc Exon Structure

    5/7 Alternative Splicing Database (ASD) splice patterns (SP) for LMO2 (see all 7 )

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7a · 7b · 7c ^ 8 ^ 9 ^ 10a · 10b · 10c ^ 11a · 11b
    SP1:                                -                 -                                             
    SP2:                                                                    -                           
    SP3:                                                                    -     -                     
    SP4:              -     -     -     -                                                               
    SP5:                                                                                                

    About this scheme

    ECgene alternative splicing isoforms for LMO2

    2 Ensembl transcripts including schematic representations:
    ENST00000257818  ENST00000395833  

    Expression
    for LMO2

    (Experimental results according to 1GeneNote and GNF BioGPS,
    probe sets-to-genes annotations according to 2GeneAnnot , 3GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
    Expression Assays from Applied Biosystems )
    About This Section

    LMO2 expression in normal and diseased human tissues

     Applied Biosystems TaqMan ® Gene Expression Assays for LMO2

    1 / 2 / 3

    3 probe-sets matching LMO2 gene


    		Affymetrix
    probe-set    		 Array  GeneAnnot data GeneNote data GeneTide data
    # genes Sensitivity Specificity Correlation Length Gb_Accession Consensus Uniqueness Score Rank
    32184_at2, 3 U95-A 1 1.00 1.00 1.00 1.00 X61118 0.60 1.00 0.82 1

    		204249_s_at2, 3 U133-A 1 1.00 1.00 -- -- NM_005574 0.60 1.00 0.82 1

    		204249_s_at2 U133Plus2 1 1.00 1.00 -- -- -- -- -- -- --
    GeneDecks  LMO2 for binary patterns associated with the probe-sets selected above  
    About GeneDecksing
    About this table    
    Data from (Publications) and GNF BioGPS
        About these images
    About these images

    CGAP SAGE TAG: --

    SOURCE GeneReport for Unigene cluster: Hs.34560

    Expression variation in blood from EXPOLDB for LMO2

    Orthologs
    for LMO2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD and/or 5MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
    About This Section
    Orthologs for LMO2 gene from 5/8 species (see all 8 )
    Organism Gene Locus Description Human
    Similarity    		 NCBI accessions
    dog
    (Canis familiaris)    		 LMO21   -- LIM domain only 2 (rhombotin-like 1) 93.75(n)
    100(a)    		 609006  XM_846184.1  XP_851277.1 
    chimpanzee
    (Pan troglodytes)    		 LMO21   -- LIM domain only 2 (rhombotin-like 1) 99.37(n)
    100(a)    		 738727  XM_001145763.1  XP_001145763.1 
    cow
    (Bos taurus)    		 LMO21   -- LIM domain only 2 (rhombotin-like 1) 93.04(n)
    99.37(a)    		 614876  NM_001076352.1  NP_001069820.1 
    rat
    (Rattus norvegicus)    		 Lmo21   -- LIM domain only 2 92.19(n)
    99.37(a)    		 362176  NM_001037358.1  NP_001032435.1 
    mouse
    (Mus musculus)    		 Lmo21, 5 2 (60.00 cM)5
    		 LIM domain only 21, 5 92.19(n)1
    99.37(a)1    		 169091  NM_008505.31  NP_032531.11 
     AK0134165  AK1918345  (see all 17)
    About this table        Species with no ortholog for LMO2

    ENSEMBL Gene Tree for LMO2

    Paralogs
    for LMO2

    (Paralogs according to 1HomoloGene
    and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
    About This Section

    Paralogs for LMO2 gene
    LMO32  LMO12  

    SNPs/Variants
    for LMO2

    (According to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
    About This Section


    10/224 NCBI SNPs in LMO2 are shown (see all 224 )
    (Click for Applied Biosystems TaqMan ® Genotyping Assay)  (see all 92)
    ABGenomic DataTranscription DataAllele Frequencies
    SNP IDValidChr 11 posSequenceRecsAA
    Chg    		TypeMoreRecsAllele
    freq    		PopTotal
    sample    		More
    ------------
    rs74471,2
    		A,C,F,H,O33837005(-) TGGCCA/GTTCTT 1 -- ut3112Minor allele frequency- G:0.15MN NA EU EA WA 1106
    rs37586401,2
    		A,C,F,H33871004(+) CTCTTA/GTCAGC 1 -- ng3122Minor allele frequency- N:0.00EA MN CSAM NA EU WA 3136
    rs37586411,2
    		A,C,F,H33871039(+) CCTGGG/ACTTTG 1 -- ng319Minor allele frequency- A:0.47MN CSAM EA EU WA 792
    rs71061121,2
    		A,C,F,H33836468(+) ATATTG/TTACAA 1 -- ng514Minor allele frequency- T:0.47EU EA WA 410
    rs37406161,2
    		A,C,F,H33837472(+) GGGACT/ACGGGC 1 -- ut31 ese322Minor allele frequency- A:0.18EA MN CSAM NA EU WA 2966
    rs22737991,2
    		A,C,F,H33870144(+) CCTTCC/TCAATT 1 -- ut51 ese3 trp312Minor allele frequency- T:0.41EA NA EU WA 2462
    rs122866991,2
    		C,F,H33871577(+) AACACG/ATGTAA 1 -- ng31 tfbs311Minor allele frequency- A:0.19EU EA WA NA 966
    rs79430061,2
    		F,H33870811(+) AGTATT/GGTCTT 1 -- ng314Minor allele frequency- G:0.02EU EA WA 420
    rs177682161,2
    		C,F33837414(+) GAAGAC/TGAAGA 1 -- ut31 ese33Minor allele frequency- T:0.01NA 142
    rs18855261,2
    		C,H33870960(+) AAAAGG/AAGACT 1 -- ng319Minor allele frequency- A:0.00EU EA WA MN CSAM 820
    About this table

    HapMap Linkage Disequilibrium images for LMO2 (up to first 250kb)

    Disorders & Mutations
    for LMO2

    (in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
    About This Section

    		 OMIM: 180385

    UniProtKB/Swiss-Prot: RBTN2_HUMAN, P25791

  • A chromosomal aberration involving LMO2 may be a cause of a form of T-cell acute
    lymphoblastic leukemia (T-ALL). Translocation t(11,14)(p13;q11) with TCRD

    • 10/16 Novoseek disease relationships for LMO2 gene (see all 16 )

    Disease   Score   Articles   PubMed IDs for Articles with Shared Sentences (# sentences)
    t-all 87.01 44 7731686 (3), 16873670 (3), 9020185 (3), 17268520 (3) (see all 17)
    severe combined immunodeficiency, x-linked 80.53 3 19440365 (1), 17726455 (1), 18227842 (1)
    leukemia t-cell 76.47 16 14645513 (2), 12727888 (1), 19440365 (1), 15994290 (1) (see all 13)
    leukemogenesis 73.68 6 17726455 (1), 7475267 (1), 7544155 (1), 17268520 (1)
    leukemia 57.08 24 19440365 (4), 17910069 (2), 9209362 (1), 9214632 (1) (see all 12)
    acute leukemia 55.01 11 9209362 (2), 10197599 (1), 9872335 (1), 15198727 (1) (see all 8)
    lymphoma lymphoblastic 42.77 2 9116269 (1)
    severe combined immunodeficiency 28.71 2 15190153 (1), 15195349 (1)
    premalignant 15.61 1 14564000 (1)
    chromosomal aberrations 8.68 1 8605871 (1)
    About this table

    Genatlas disease: LMO2
    acute lymphoblastic leukemia (T-ALL),with translocations t(11;14)(p13;q11),t(7;11)(p35;p13)

    Human Genome Epidemiology Navigator: LMO2 (2 documents)
    Tumor Gene Database: LMO2

    Medical News
    for LMO2

    (Possibly Related Articles in Doctor's Guide)
    About This Section

    		   --

    Publications
    for LMO2

    (in PubMed. Associations of this gene to articles via 1Novoseek, 2HGNC, 3Entrez Gene, 4UniProtKB/Swiss-Prot, 5UniProtKB/TrEMBL, 6GAD, and/or 7PharmGKB)
    About This Section

    		10/129 PubMed articles for LMO2 gene (see all 129 ):

    Search for LMO2

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

     ANDOR
    Aliases
    Free Text  
      Query String
    		PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    Genome Databases showing LMO2

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
    About This Section
    Entrez Gene: 4005 HGNC: 6642 AceView: LMO2 Ensembl:ENSG00000135363 euGenes: HUgn4005
    ECgene: LMO2 H-InvDB: LMO2

    Other Databases showing LMO2

    (According to HUGE)
    About This Section

    		   --

    Specialized Databases showing LMO2

    (According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    ATLAS Chromosomes in Cancer entry for LMO2 Genetics and Cytogenetics in Oncology and Haematology

    Licensable Technologies
    for LMO2

    (Available from WIS Yeda, Salk, Tufts)
    About This Section

    		  --

    Services
    for LMO2

    (Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
    Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
    Enzo Life Sciences, and/or Tocris Bioscience)
    About This Section



    Products for LMO2:
     TaqMan ® Gene Expression Assays
     TaqMan ® Genotyping Assays
    		  Free SNP selection tool



      Invitrogen iPath Pathways  Invitrogen BLOCK-iT™ RNAi
      Invitrogen Antibodies  Invitrogen Assays
      Invitrogen Clones  Invitrogen Q-PCR Products
      Invitrogen Human Recombinant Kinases  Invitrogen Custom Antibody and Peptide Service
      Invitrogen Proteins / Assays / Screening Services  Search Invitrogen catalog for LMO2-related products

     Millipore Custom Antibody & Bulk Services
     Millipore Preclinical / Clinical Development Services
     Millipore Immunoassay Services
     Millipore Target Screening & Profiling Services


     Predesigned and custom siRNAs for LMO2 Antibodies for LMO2
     Explore super-pooled esiRNAs Browse proteins at Sigma-Aldrich
     Lentivirus-delivered shRNAs for LMO2 Browse small molecules at Sigma-Aldrich
     "Your Favorite Gene" Pathwaysfeedback


      
     Antibodies   Primer Pairs  
     Cell Culture Products   ELISAs  
     Flow Cytometry Kits   Protease Activity Assays & Reagents  
     Cell Selection/Detection Kits & Reagents   ELISA/Assay Development Kits & Reagents  
     Multiplex/Array Assay Kits & Reagents   ELISpot Kits & Development Modules  
     Recombinant & Natural Proteins  

     Recombinant Proteins (LMO2)
     Antibodies (LMO2)
     Chimera RNAi (LMO2)
     Custom Service for Mouse Mab
     Custom Service for Rabbit Pab from Full-length Protein
      
     Search for Antibodies & Assays

     Recombinant Proteins
    (LMO2)
     Antibodies (LMO2)
     Tagged/untagged cDNA clones
     Validated SYBR primer pairs
     Purified proteins from HEK293T cells
     Western blot validated antibodies
     shRNA in GFP-retroviral vector
     Search Tocris compounds for LMO2




     Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies
     Antibodies for LMO2

    GeneCards Homepage    -    Last full update: 2 Jul 2009        Incremental update: 13 Oct 2009

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