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Aliases for LMNTD2 Gene

Aliases for LMNTD2 Gene

  • Lamin Tail Domain Containing 2 2 3
  • C11orf35 3 4
  • Chromosome 11 Open Reading Frame 35 2

External Ids for LMNTD2 Gene

Previous HGNC Symbols for LMNTD2 Gene

  • C11orf35

Summaries for LMNTD2 Gene

GeneCards Summary for LMNTD2 Gene

LMNTD2 (Lamin Tail Domain Containing 2) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for LMNTD2 Gene

Genomics for LMNTD2 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for LMNTD2 Gene

554,850 bp from pter
560,780 bp from pter
5,931 bases
Minus strand

Genomic View for LMNTD2 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for LMNTD2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for LMNTD2 Gene

No data available for Regulatory Elements for LMNTD2 Gene

Proteins for LMNTD2 Gene

  • Protein details for LMNTD2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Lamin tail domain-containing protein 2
    Protein Accession:

    Protein attributes for LMNTD2 Gene

    634 amino acids
    Molecular mass:
    70379 Da
    Quaternary structure:
    No Data Available

neXtProt entry for LMNTD2 Gene

Proteomics data for LMNTD2 Gene at MOPED

Post-translational modifications for LMNTD2 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for LMNTD2 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for LMNTD2 Gene

Domains & Families for LMNTD2 Gene

Protein Domains for LMNTD2 Gene


Graphical View of Domain Structure for InterPro Entry



  • Contains 1 LTD domain.
  • Contains 1 LTD domain.
genes like me logo Genes that share domains with LMNTD2: view

No data available for Gene Families and Suggested Antigen Peptide Sequences for LMNTD2 Gene

Function for LMNTD2 Gene

Phenotypes for LMNTD2 Gene

GenomeRNAi human phenotypes for LMNTD2:
genes like me logo Genes that share phenotypes with LMNTD2: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for LMNTD2 Gene

Localization for LMNTD2 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for LMNTD2 Gene

Pathways & Interactions for LMNTD2 Gene

SuperPathways for LMNTD2 Gene

No Data Available

Interacting Proteins for LMNTD2 Gene

Gene Ontology (GO) - Biological Process for LMNTD2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0048026 positive regulation of mRNA splicing, via spliceosome IEA --
genes like me logo Genes that share ontologies with LMNTD2: view

No data available for Pathways by source and SIGNOR curated interactions for LMNTD2 Gene

Drugs & Compounds for LMNTD2 Gene

No Compound Related Data Available

Transcripts for LMNTD2 Gene

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for LMNTD2

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for LMNTD2 Gene

No ASD Table

Relevant External Links for LMNTD2 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for LMNTD2 Gene

mRNA expression in normal human tissues for LMNTD2 Gene

Protein differential expression in normal tissues from HIPED for LMNTD2 Gene

This gene is overexpressed in Fetal heart (58.2) and Plasma (6.1).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for LMNTD2 Gene

genes like me logo Genes that share expression patterns with LMNTD2: view

Protein tissue co-expression partners for LMNTD2 Gene

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for LMNTD2 Gene

Orthologs for LMNTD2 Gene

This gene was present in the common ancestor of chordates.

Orthologs for LMNTD2 Gene

Organism Taxonomy Gene Similarity Type Details
(Canis familiaris)
Mammalia C18H11orf35 35
  • 71.33 (n)
  • 58.76 (a)
C11orf35 36
  • 52 (a)
(Mus musculus)
Mammalia 1600016N20Rik 35
  • 67.53 (n)
  • 55.27 (a)
1600016N20Rik 16
1600016N20Rik 36
  • 47 (a)
(Pan troglodytes)
Mammalia C11H11orf35 35
  • 98.62 (n)
  • 97.65 (a)
C11orf35 36
  • 97 (a)
(Rattus norvegicus)
Mammalia RGD1307439 35
  • 65.46 (n)
  • 53.89 (a)
(Bos Taurus)
Mammalia C11orf35 36
  • 54 (a)
(Monodelphis domestica)
Mammalia C11orf35 36
  • 32 (a)
(Anolis carolinensis)
Reptilia C11orf35 36
  • 41 (a)
Species with no ortholog for LMNTD2:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for LMNTD2 Gene

Gene Tree for LMNTD2 (if available)
Gene Tree for LMNTD2 (if available)

Paralogs for LMNTD2 Gene

No data available for Paralogs for LMNTD2 Gene

Variants for LMNTD2 Gene

Sequence variations from dbSNP and Humsavar for LMNTD2 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type MAF
rs936466 -- 557,342(-) TGGCA(A/G)GTGAA intron-variant
rs936467 -- 556,121(-) CGCCC(C/T)TCCAG intron-variant
rs4963199 -- 557,661(+) GGAAG(C/T)CAGTG intron-variant
rs7938269 -- 556,857(-) GCCGG(C/G)AGCTA reference, synonymous-codon, nc-transcript-variant
rs11246185 -- 556,785(+) CTGAG(C/G/T)GGGTG intron-variant

Variation tolerance for LMNTD2 Gene

Residual Variation Intolerance Score: 99.01% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 4.96; 68.12% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for LMNTD2 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for LMNTD2 Gene

Disorders for LMNTD2 Gene

Relevant External Links for LMNTD2

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with LMNTD2: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for LMNTD2 Gene

Publications for LMNTD2 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 67
  2. Human chromosome 11 DNA sequence and analysis including novel gene identification. (PMID: 16554811) Taylor T.D. … Sakaki Y. (Nature 2006) 67
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 67

Products for LMNTD2 Gene

Sources for LMNTD2 Gene

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