LMNB2 Gene
protein-coding GIFtS: 62
GCID: GC19M002428
|
|
lamin B2
(Previous symbol: LMN2)
| |
Aliases
for LMNB2 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Lamin B21 2 | | LMN21 2 3 5 | | LAMB22 | | Lamin-B21 |
Export aliases for LMNB2 gene to outside databasesPrevious GC identifers: GC19U990060 GC19M002498 GC19M002368 GC19M002379 GC19M002200 |
Summaries
for LMNB2 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for LMNB2:
This gene encodes a B type nuclear lamin. The nuclear lamina consists of a two-dimensional matrix of proteins locatednext to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved inevolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated.Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebratelamins consist of two types, A and B. Mutations in this gene are associated with acquired partial lipodystrophy.(provided by RefSeq, May 2012)
UniProtKB/Swiss-Prot: LMNB2_HUMAN, Q03252Function: Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclearmembrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin
|
Genomic Views
for LMNB2 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000019.9 NC_018930.1 NT_011255.14
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the LMNB2 gene promoter:
c-Fos c-Rel AP-1 ATF-2 MyoD c-Jun
Other transcription factors
Search SABiosciences Chromatin IP Primers for LMNB2
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat LMNB2 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 19p13.3 Ensembl cytogenetic band: 19p13.3 HGNC cytogenetic band: 19p13.3LMNB2 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 19 GeneLoc Exon Structure GeneLoc location for GC19M002428: view genomic region
(about GC identifiers)
Start:
|
2,427,636 bp from pter |
End:
|
2,456,994 bp from pter |
Size:
|
29,359 bases |
Orientation:
|
minus strand |
|
Proteins
for LMNB2 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: LMNB2_HUMAN, Q03252 (See
protein sequence)Recommended Name: Lamin-B2 precursor Size: 600 amino acids; 67689 Da
Subunit: Interacts with TMEM43 (By similarity)
Subcellular location: Nucleus inner membrane; Lipid-anchor; Nucleoplasmic side
Miscellaneous: The structural integrity of the lamina is strictly controlled by the cell cycle, as seen by thedisintegration and formation of the nuclear envelope in prophase and telophase, respectively
1 PDB 3D structure from  and Proteopedia  for LMNB2:2LLL (3D)
Secondary accessions: O75292 Q14734 Q96DF6Explore the universe of human proteins at neXtProt for LMNB2: NX_Q03252
Post-translational modifications:
B-type lamins undergo a series of modifications, such as farnesylation and phosphorylation. Increased phosphorylationof the lamins occurs before envelope disintegration and probably plays a role in regulating lamin associations1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q03252
LMNB2 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_116126.3
ENSEMBL proteins: ENSP00000327054 ENSP00000462730
Human Recombinant Protein Products:
Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table
LMNB2 for ontologies About GeneDecksing
LMNB2 Antibody Products:
Assay Products for LMNB2: |
Protein
Domains /
Families
for LMNB2 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
LMNB2 for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q03252ProtoNet protein and cluster: Q03252 2 Blocks protein families: IPB001322 Intermediate filament IPB001664 Intermediate filament protein
UniProtKB/Swiss-Prot: LMNB2_HUMAN, Q03252Similarity: Belongs to the intermediate filament family |
Function
for LMNB2 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: LMNB2_HUMAN, Q03252Function: Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclearmembrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin Genatlas biochemistry entry for LMNB2:lamin,type B2
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for LMNB2 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for LMNB2 (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: LMNB2 (NM_032737) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for LMNB2 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat LMNB2 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for LMNB2 |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0003674 | molecular_function |
ND | -- | | GO:0005198 | structural molecule activity |
IEA | -- |
LMNB2 for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for LMNB2:
Animal Models:
Mouse knock-out Lmnb2tm1Yxz for LMNB2
11 MGI mutant phenotypes (inferred from 4 alleles ) (MGI details for Lmnb2):
LMNB2 for phenotypes About GeneDecksing
|
Pathways & Interactions
for LMNB2 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways - 5/6 super-pathways (see all 6) About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Apoptosis and survival_Caspase cascade | | | 2 | Granzyme Pathway | | | 3 | Cytoskeletal Signaling | | | 4 | Apoptosis and Autophagy | | | 5 | TWEAK Pathway | |
Pathway sources
See GeneCards unified pathways
Show all pathways
2 EMD Millipore Pathways for LMNB2
4 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for LMNB2
2 
Cell Signaling Technology (CST) Pathways for LMNB2
2  GeneGo (Thomson Reuters) Pathways for LMNB2
2  BioSystems Pathways for LMNB2
LMNB2 for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for LMNB2
STRING Interaction
Network Preview (showing 5 interactants - click image to see 16)
5/22 Interacting proteins for LMNB2 (Q032522, 3 ENSP000003270544) via UniProtKB, MINT, STRING, and/or I2D (see all 22)About this table
Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0008150 | biological_process |
ND | -- |
LMNB2 for ontologies About GeneDecksing
|
Drugs & Compounds
for LMNB2 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
LMNB2 for compounds About GeneDecksing
 Browse Tocris compounds for LMNB2
2 Novoseek chemical compound relationships for LMNB2 gene About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| dihydrofolate |
32.3 |
1 |
10577395 (1) |
| serine |
3 |
1 |
15546914 (1) |
Search CenterWatch for drugs/clinical trials and news about LMNB2
|
Transcripts
for LMNB2 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for LMNB2 gene: NM_032737.3 Unigene Cluster for LMNB2: Lamin B2 Hs.744015 [show with all ESTs]Unigene Representative Sequence: NM_0327379 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000532465 ENST00000325327(uc002lvy.3) ENST00000524597 ENST00000534597
ENST00000475819 ENST00000490554 ENST00000527409 ENST00000534495 ENST00000582871
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for LMNB2 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for LMNB2 (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: LMNB2 (NM_032737) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for LMNB2 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat LMNB2 |
Additional cDNA sequence: AK129641.1 BC006513.2 BC006551.2 BC009267.2 BT007441.1 22 DOTS entries: DT.100038869 DT.92455928 DT.121414790 DT.97857995 DT.454046 DT.121414403 DT.100789803 DT.95263113 DT.95263123 DT.121414616 DT.95263124 DT.100789807 DT.100814691 DT.40116196 DT.95263125 DT.100789815 DT.121414673 DT.95324050 DT.121414607 DT.95114992 DT.100814697 DT.445441 24/529 AceView cDNA sequences (see all 529): NM_017572 BM819839 BM687311 BQ940812 AW939139 BM773201 BM802119 CA426786 AA634800 AL137565 BQ575598 BM696657 BQ073318 AI459075 BM757169 AK001730 F29206 BG176606 AA083866 BG169666 AW248577 BQ422832 AI739114 CR621909
GeneLoc Exon Structure
5/6 Alternative Splicing Database (ASD) splice patterns (SP) for LMNB2 (see all 6) About this scheme
| ExUns: | 1 | ^ | 2a | · | 2b | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8a | · | 8b | · | 8c | · | 8d | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13 |
|---|
|
| SP1: | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for LMNB2
|
Expression
for LMNB2 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| LMNB2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CCTAATGTGT
About this image
See LMNB2 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for LMNB2
SOURCE GeneReport for Unigene cluster: Hs.744015
SABiosciences Expression via Pathway-Focused PCR Array including LMNB2:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for LMNB2
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat LMNB2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat LMNB2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat LMNB2 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for LMNB2 |
Orthologs
for LMNB2 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for LMNB2 gene from 4/19 species (see all 19) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
LMNB21 |
lamin B2 |
74.7(n)
81.11(a) |
|
396222 NM_205285.1 NP_990616.1 |
African clawed frog
(Xenopus laevis) |
Amphibia |
X54099.12 |
-- |
73.88(n) |
|
X54099.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
lmnb22 |
lamin B2 |
75.94(n) |
|
30196 AJ005936.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
LamC1 |
Lamin C |
51.66(n)
39.38(a) |
|
36615 NM_079018.2 NP_523742.2 |
ENSEMBL Gene Tree for LMNB2 (if available)
TreeFam Gene Tree for LMNB2 (if available) |
Paralogs
for LMNB2 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for LMNB2 gene
- LMNB12 SYNM2 VIM2 INA2 LMNA2 NES2 PRPH2 DES2
- NEFM2 NEFH2 GFAP2
10 SIMAP similar genes for LMNB2 using alignment to 2 protein entries: LMNB2_HUMAN (see all proteins):LMNB1 LMNA DES KRTHB1 PRPH KRTHB6
VIM K14 KRT4 KRT5
LMNB2 for paralogs About GeneDecksing
|
Genomic Variants
for LMNB2 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 19 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for LMNB2 (2427636 - 2456994 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for LMNB2
2 Indels: 67434 26230
Human Gene Mutation Database (HGMD): LMNB2
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing LMNB2 |
|
Disorders
/ Diseases
for LMNB2 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
LMNB2 for disorders About GeneDecksing
OMIM gene information: 150341
OMIM disorders: 608709
UniProtKB/Swiss-Prot: LMNB2_HUMAN, Q03252
Defects in LMNB2 are a cause of partial acquired lipodystrophy (APLD) [MIM:608709]. A rare childhood diseasecharacterized by loss of subcutaneous fat from the face and trunk. Fat deposition on the pelvic girdle and lower limbsis normal or excessive. Most frequently, onset between 5 and 15 years of age. Most affected subjects are females andsome show no other abnormality, but many develop glomerulonephritis, diabetes mellitus, hyperlipidemia, and complementdeficiency. Mental retardation in some cases. APLD is a sporadic disorder of unknown etiology
15  diseases for LMNB2: About MalaCardspelger-huet anomaly lipodystrophy emery-dreifuss muscular dystrophy dna topoisomerase i
reynolds syndrome muscular dystrophy complement deficiency basal cell carcinoma
progeria hyperlipidemia cardiomyopathy cerebritis
schizophrenia immunodeficiency carcinoma
3 diseases from the University of Copenhagen DISEASES database for LMNB2:Lipodystrophy Emery-Dreifuss muscular dystrophy Pelger-Huet anomaly 1 Novoseek disease relationship for LMNB2 gene About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| partial lipodystrophy |
83.6 |
1 |
17467691 (1) |
Human Genome Epidemiology (HuGE) Navigator: LMNB2 (3 documents)
Export disorders for LMNB2 gene to outside databases
|
Publications
for LMNB2 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for LMNB2 gene, integrated from 9 sources (see all 105):
(articles sorted by number of sources associating them with LMNB2) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The gene for a novel human lamin maps at a highly transcribed locus of chromosome 19 which replicates at the onset of S-phase. (PubMed id 1630457)1, 2, 3, 9 Biamonti G.... Falaschi A. (1992)
- Sequencing of the reannotated LMNB2 gene reveals novel mutations in patients with acquired partial lipodystrophy. (PubMed id 16826530)1, 2, 9 Hegele R.A.... Durrington P.N. (2006)
- Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
- The DNA sequence and biology of human chromosome 19. (PubMed id 15057824)1, 2 Grimwood J.... Lucas S.M. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- S-phase phosphorylation of lamin B2. (PubMed id 8543011)1, 9 Kill I.R. and Hutchison C.J. (1995)
- Noncanonical DNA elements in the lamin B2 origin of DNA replication. (PubMed id 15611042)1, 9 Kusic J....Stefanovic D. (2005)
- In vitro protein-DNA interactions at the human lamin B2 replication origin. (PubMed id 12902329)1, 9 Stefanovic D....Falaschi A. (2003)
- Modular structure of the human lamin B2 replicator. (PubMed id 15024083)1, 9 Paixao S....Biamonti G. (2004)
- Ku80 binds to human replication origins prior to the assembly of the ORC complex. (PubMed id 15910003)1, 9 Sibani S....Zannis-Hadjopoulos M. (2005)
|
External Searches for LMNB2 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing LMNB2 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing LMNB2 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing LMNB2 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for LMNB2 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for LMNB2 gene:
Search GeneIP for patents involving LMNB2
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for LMNB2 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | OriGene Antibodies for LMNB2 | | OriGene shRNA RFP for LMNB2 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for LMNB2 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for LMNB2 | | | OriGene Protein Over-expression Lysate for LMNB2 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for LMNB2 | | OriGene 3'-UTR Clone for LMNB2 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for LMNB2 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for LMNB2 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for LMNB2 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for LMNB2 | | OriGene Custom Protein Services for LMNB2 | | | OriGene Custom Immunoassay Development | | |
| |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat LMNB2 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing LMNB2 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat LMNB2 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat LMNB2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat LMNB2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat LMNB2 |
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| | Antibodies & Assays for LMNB2
(Lamin B2) |
| | | | Search Tocris compounds for LMNB2 |
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 | | | LMNB2 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for LMNB2 |
|  |  |  | | | | ThermoFisher Antibodies for LMNB2 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat LMNB2 |
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