Free for academic non-profit institutions. Other users need a Commercial license

Aliases for LLCFC1 Gene

Aliases for LLCFC1 Gene

  • LLLL And CFNLAS Motif Containing 1 2 3
  • C7orf34 3 4 5
  • Chromosome 7 Open Reading Frame 34 2 5
  • MSSP-Binding Protein CTM-1 3 4
  • Uncharacterized Protein C7orf34 3
  • Ctm-1 3

External Ids for LLCFC1 Gene

Previous HGNC Symbols for LLCFC1 Gene

  • C7orf34

Summaries for LLCFC1 Gene

GeneCards Summary for LLCFC1 Gene

LLCFC1 (LLLL And CFNLAS Motif Containing 1) is a Protein Coding gene.

Additional gene information for LLCFC1 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for LLCFC1 Gene

Genomics for LLCFC1 Gene

Regulatory Elements for LLCFC1 Gene

Enhancers for LLCFC1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH07H142908 0.9 Ensembl ENCODE 12.2 -29.6 -29613 2.4 CTCF MNT ELF1 RAD21 CTBP1 ZNF316 IKZF1 ID3 FOS MAFK KEL TRPV5 LLCFC1 EPHB6 OR9P1P OR6V1 TRPV6
GH07H142927 0.8 Ensembl ENCODE 12.6 -11.7 -11743 1.2 NFIC POLR2A CEBPB MAX CEBPG REST GABPA LLCFC1 KEL TRPV5 TRPV6
GH07H143126 0.8 Ensembl ENCODE 10.1 +186.9 186858 0.4 GATA3 JUND FOS GABPA KEL LLCFC1 TRPV5 TMEM139 PIP OR6W1P
GH07H142838 0.8 ENCODE 9.8 -100.7 -100680 0.2 PKNOX1 TBL1XR1 TAL1 ZKSCAN1 FOSL1 TCF12 MTA3 ZNF316 CTBP1 GATA2 KEL TRPV5 LLCFC1 EPHB6 TRBV30
GH07H142866 0.6 ENCODE 10.9 -72.9 -72863 0.2 CTCF CTBP1 IKZF1 SMC3 ZNF143 REST RAD21 TRPV5 LLCFC1 KEL GC07P143766 EPHB6
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around LLCFC1 on UCSC Golden Path with GeneCards custom track

Genomic Locations for LLCFC1 Gene

Genomic Locations for LLCFC1 Gene
chr7:142,939,343-142,940,870
(GRCh38/hg38)
Size:
1,528 bases
Orientation:
Plus strand
chr7:142,636,440-142,637,957
(GRCh37/hg19)

Genomic View for LLCFC1 Gene

Genes around LLCFC1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
LLCFC1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for LLCFC1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for LLCFC1 Gene

Proteins for LLCFC1 Gene

  • Protein details for LLCFC1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96L11-CG034_HUMAN
    Recommended name:
    Uncharacterized protein C7orf34
    Protein Accession:
    Q96L11
    Secondary Accessions:
    • A4D2H8
    • C9JTW1
    • Q8TDV6

    Protein attributes for LLCFC1 Gene

    Size:
    122 amino acids
    Molecular mass:
    13527 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for LLCFC1 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for LLCFC1 Gene

Post-translational modifications for LLCFC1 Gene

No Post-translational modifications

Other Protein References for LLCFC1 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for LLCFC1 Gene

Domains & Families for LLCFC1 Gene

Gene Families for LLCFC1 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins
  • Predicted membrane proteins

Protein Domains for LLCFC1 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for LLCFC1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with LLCFC1: view

No data available for UniProtKB/Swiss-Prot for LLCFC1 Gene

Function for LLCFC1 Gene

Phenotypes for LLCFC1 Gene

genes like me logo Genes that share phenotypes with LLCFC1: view

Animal Model Products

Inhibitory RNA Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for LLCFC1 Gene

Localization for LLCFC1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for LLCFC1 Gene

Secreted.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for LLCFC1 gene
Compartment Confidence
extracellular 4
plasma membrane 2

Gene Ontology (GO) - Cellular Components for LLCFC1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005576 extracellular region IEA --
genes like me logo Genes that share ontologies with LLCFC1: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for LLCFC1 Gene

Pathways & Interactions for LLCFC1 Gene

SuperPathways for LLCFC1 Gene

No Data Available

Interacting Proteins for LLCFC1 Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
http://version10.5.string-db.org/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000386450%0d%0a9606.ENSP00000366902%0d%0a
Selected Interacting proteins: Q96L11-CG034_HUMAN ENSP00000386450 for LLCFC1 Gene via IID STRING

Gene Ontology (GO) - Biological Process for LLCFC1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for LLCFC1 Gene

Drugs & Compounds for LLCFC1 Gene

No Compound Related Data Available

Transcripts for LLCFC1 Gene

mRNA/cDNA for LLCFC1 Gene

(1) REFSEQ mRNAs :
(4) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Inhibitory RNA Products

Alternative Splicing Database (ASD) splice patterns (SP) for LLCFC1 Gene

No ASD Table

Relevant External Links for LLCFC1 Gene

GeneLoc Exon Structure for
LLCFC1
ECgene alternative splicing isoforms for
LLCFC1

Expression for LLCFC1 Gene

NURSA nuclear receptor signaling pathways regulating expression of LLCFC1 Gene:

LLCFC1
No Expression Related Data Available

Primer Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for LLCFC1 Gene

Orthologs for LLCFC1 Gene

This gene was present in the common ancestor of mammals.

Orthologs for LLCFC1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C7H7orf34 33
  • 99.32 (n)
C7orf34 34
  • 99 (a)
OneToOne
dog
(Canis familiaris)
Mammalia C16H7orf34 33
  • 78.25 (n)
C7orf34 34
  • 53 (a)
OneToOne
cow
(Bos Taurus)
Mammalia C4H7orf34 33
  • 75.98 (n)
C7orf34 34
  • 62 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia LOC680112 33
  • 68.32 (n)
mouse
(Mus musculus)
Mammalia 1700034O15Rik 33 16 34
  • 65.68 (n)
oppossum
(Monodelphis domestica)
Mammalia C7orf34 34
  • 42 (a)
OneToOne
Species where no ortholog for LLCFC1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for LLCFC1 Gene

ENSEMBL:
Gene Tree for LLCFC1 (if available)
TreeFam:
Gene Tree for LLCFC1 (if available)

Paralogs for LLCFC1 Gene

No data available for Paralogs for LLCFC1 Gene

Variants for LLCFC1 Gene

Sequence variations from dbSNP and Humsavar for LLCFC1 Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type
rs1000200856 -- 142,938,033(+) GTCTG(C/T)TGTAT nc-transcript-variant, upstream-variant-2KB
rs1000484211 -- 142,939,119(+) GAAGA(C/T)ATCAT upstream-variant-2KB
rs1002936225 -- 142,940,894(+) CTTAA(A/T)CCAAG intron-variant, downstream-variant-500B, upstream-variant-2KB
rs1004598054 -- 142,940,007(+) GTGTG(G/T)GTAAG intron-variant, upstream-variant-2KB
rs1004665132 -- 142,938,763(+) CTCTC(A/C/T)GTTCA intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for LLCFC1 Gene

Variant ID Type Subtype PubMed ID
nsv831168 CNV gain 17160897
nsv526015 CNV gain 19592680
nsv520735 CNV loss 19592680
nsv1030700 CNV gain 25217958
esv2759569 CNV loss 17122850

Variation tolerance for LLCFC1 Gene

Residual Variation Intolerance Score: 90.7% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for LLCFC1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
LLCFC1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for LLCFC1 Gene

Disorders for LLCFC1 Gene

Relevant External Links for LLCFC1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
LLCFC1
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
LLCFC1

No disorders were found for LLCFC1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for LLCFC1 Gene

Publications for LLCFC1 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 60
  2. Human chromosome 7: DNA sequence and biology. (PMID: 12690205) Scherer SW … Tsui LC (Science (New York, N.Y.) 2003) 3 4 60
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 2 3 60
  4. Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing. (PMID: 26871637) Yang X … Vidal M (Cell 2016) 3 60
  5. Transcriptional maps of 10 human chromosomes at 5-nucleotide resolution. (PMID: 15790807) Cheng J … Gingeras TR (Science (New York, N.Y.) 2005) 3 60

Products for LLCFC1 Gene

Sources for LLCFC1 Gene

Content
Loading form....