Aliases for LIPN Gene
External Ids for LIPN Gene
Previous HGNC Symbols for LIPN Gene
Previous GeneCards Identifiers for LIPN Gene
The gene encodes a lipase that is highly expressed in granular keratinocytes in the epidermis, and plays a role in the differentiation of keratinocytes. Mutations in this gene are associated with lamellar ichthyosis type 4. [provided by RefSeq, Dec 2011]
GeneCards Summary for LIPN Gene
LIPN (Lipase, Family Member N) is a Protein Coding gene. Diseases associated with LIPN include ichthyosis, congenital, autosomal recessive 8 and facial nerve disease. GO annotations related to this gene include hydrolase activity, acting on ester bonds. An important paralog of this gene is LIPA.
UniProtKB/Swiss-Prot for LIPN Gene
Plays a highly specific role in the last step of keratinocyte differentiation. May have an essential function in lipid metabolism of the most differentiated epidermal layers.