Aliases for LIPH Gene
External Ids for LIPH Gene
Previous GeneCards Identifiers for LIPH Gene
This gene encodes a membrane-bound member of the mammalian triglyceride lipase family. It catalyzes the production of 2-acyl lysophosphatidic acid (LPA), which is a lipid mediator with diverse biological properties that include platelet aggregation, smooth muscle contraction, and stimulation of cell proliferation and motility. [provided by RefSeq, Jul 2008]
GeneCards Summary for LIPH Gene
LIPH (Lipase, Member H) is a Protein Coding gene. Diseases associated with LIPH include hypotrichosis 7 and hepatic lipase deficiency. GO annotations related to this gene include heparin binding and phospholipase activity. An important paralog of this gene is LPL.
UniProtKB/Swiss-Prot for LIPH Gene
Hydrolyzes specifically phosphatidic acid (PA) to produce 2-acyl lysophosphatidic acid (LPA; a potent bioactive lipid mediator) and fatty acid. Does not hydrolyze other phospholipids, like phosphatidylserine (PS), phosphatidylcholine (PC) and phosphatidylethanolamine (PE) or triacylglycerol (TG).