Aliases for LIPG Gene
External Ids for LIPG Gene
Previous GeneCards Identifiers for LIPG Gene
The protein encoded by this gene has substantial phospholipase activity and may be involved in lipoprotein metabolism and vascular biology. This protein is designated a member of the TG lipase family by its sequence and characteristic lid region which provides substrate specificity for enzymes of the TG lipase family. [provided by RefSeq, Jul 2008]
GeneCards Summary for LIPG Gene
LIPG (Lipase, Endothelial) is a Protein Coding gene. Diseases associated with LIPG include hyperalphalipoproteinemia. Among its related pathways are Metabolism and Glycerolipid metabolism. GO annotations related to this gene include heparin binding and phospholipase activity. An important paralog of this gene is LPL.
UniProtKB/Swiss-Prot for LIPG Gene
Has phospholipase and triglyceride lipase activities. Hydrolyzes high density lipoproteins (HDL) more efficiently than other lipoproteins. Binds heparin
Endothelial lipase (LIPG) is a vascular lipase which is synthesized in endothelial cells. LIPG hydrolyzes the phospholipids of VLDL, chylomicrons and HDL; it also displays triglyceride lipase activity.