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Aliases for LINC01599 Gene

Subcategory (RNA class) for LINC01599 Gene

non-coding RNA

Quality Score for this RNA gene is

12

Aliases for LINC01599 Gene

  • Long Intergenic Non-Protein Coding RNA 1599 2 3
  • C14orf183 3 4
  • Chromosome 14 Open Reading Frame 183 2

External Ids for LINC01599 Gene

Previous HGNC Symbols for LINC01599 Gene

  • C14orf183

Summaries for LINC01599 Gene

GeneCards Summary for LINC01599 Gene

LINC01599 (Long Intergenic Non-Protein Coding RNA 1599) is an RNA Gene, and is affiliated with the non-coding RNA class.

Additional gene information for LINC01599 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for LINC01599 Gene

Genomics for LINC01599 Gene

GeneHancer (GH) Regulatory Elements for LINC01599 Gene

Promoters and enhancers for LINC01599 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH14I050090 Enhancer 0.5 dbSUPER 550.8 +1.2 1216 2 TCF12 CTBP1 SOX6 CBFA2T3 CBFA2T2 LINC01588 LINC01599 VCPKMT ATP5S ENSG00000251792
GH14I050071 Enhancer 0.8 FANTOM5 dbSUPER 2.4 +21.4 21402 0.2 NR2F1 TRIM22 IKZF1 TARDBP NBN ZNF24 RUNX3 IKZF2 VCPKMT LINC01588 LINC01599 RPL36AL RN7SKP193 GC14P050088
GH14I049906 Enhancer 1.3 FANTOM5 Ensembl ENCODE dbSUPER 1.3 +184.6 184649 2.8 JUN MAX BATF FOSL1 POLR2A PRDM10 FOSL2 FOS RFX1 JUNB LINC01588 RPL36AL ARF6 LINC01599 MGAT2 ENSG00000274704 RNU6-189P
GH14I050095 Enhancer 1 FANTOM5 Ensembl ENCODE dbSUPER 0.8 -3.9 -3882 2.3 SPI1 VCPKMT RNU6-189P SOS2 ATP5S RPL36AL ARF6 LINC01588 NEMF DNAAF2 LINC01599
GH14I050115 Promoter/Enhancer 2.2 EPDnew Ensembl ENCODE dbSUPER 0.3 -23.9 -23917 2.3 HDGF PKNOX1 SMAD1 ARID4B SIN3A DMAP1 YY1 SLC30A9 POLR2B ZNF207 VCPKMT RHOQP1 LRR1 ENSG00000270062 ATP5S LINC01588 LINC01599 SOS2
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around LINC01599 on UCSC Golden Path with GeneCards custom track

Genomic Locations for LINC01599 Gene

Genomic Locations for LINC01599 Gene
chr14:50,083,651-50,092,643
(GRCh38/hg38)
Size:
8,993 bases
Orientation:
Minus strand
chr14:50,550,369-50,559,361
(GRCh37/hg19)

Genomic View for LINC01599 Gene

Genes around LINC01599 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
LINC01599 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for LINC01599 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for LINC01599 Gene

Proteins for LINC01599 Gene

  • Protein details for LINC01599 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8WXQ3-CN183_HUMAN
    Recommended name:
    Putative uncharacterized protein encoded by LINC01599
    Protein Accession:
    Q8WXQ3

    Protein attributes for LINC01599 Gene

    Size:
    324 amino acids
    Molecular mass:
    35482 Da
    Quaternary structure:
    No Data Available

neXtProt entry for LINC01599 Gene

Post-translational modifications for LINC01599 Gene

No Post-translational modifications

No data available for DME Specific Peptides for LINC01599 Gene

Domains & Families for LINC01599 Gene

Protein Domains for LINC01599 Gene

ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with LINC01599: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for LINC01599 Gene

Function for LINC01599 Gene

Phenotypes From GWAS Catalog for LINC01599 Gene

Phenotypes for LINC01599 Gene

GenomeRNAi human phenotypes for LINC01599:
genes like me logo Genes that share phenotypes with LINC01599: view

Animal Model Products

miRNA for LINC01599 Gene

miRTarBase miRNAs that target LINC01599

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for LINC01599 Gene

Localization for LINC01599 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for LINC01599 gene
Compartment Confidence
nucleus 2
cytosol 2
extracellular 1
endoplasmic reticulum 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for LINC01599 Gene

Pathways & Interactions for LINC01599 Gene

SuperPathways for LINC01599 Gene

No Data Available

Interacting Proteins for LINC01599 Gene

Gene Ontology (GO) - Biological Process for LINC01599 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for LINC01599 Gene

Drugs & Compounds for LINC01599 Gene

No Compound Related Data Available

Transcripts for LINC01599 Gene

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for LINC01599 Gene

No ASD Table

Relevant External Links for LINC01599 Gene

GeneLoc Exon Structure for
LINC01599
ECgene alternative splicing isoforms for
LINC01599

Expression for LINC01599 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for LINC01599 Gene

NURSA nuclear receptor signaling pathways regulating expression of LINC01599 Gene:

LINC01599
genes like me logo Genes that share expression patterns with LINC01599: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for LINC01599 Gene

Orthologs for LINC01599 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for LINC01599 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C14H14orf183 33
  • 99.07 (n)
Species where no ortholog for LINC01599 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

No data available for Evolution for LINC01599 Gene

Paralogs for LINC01599 Gene

No data available for Paralogs for LINC01599 Gene

Variants for LINC01599 Gene

Sequence variations from dbSNP and Humsavar for LINC01599 Gene

SNP ID Clin Chr 14 pos Variation AA Info Type
rs1000030067 -- 50,030,756(-) A/C intron_variant
rs1000062717 -- 50,076,785(-) C/T intron_variant
rs1000092491 -- 50,068,736(-) GG/GGG intron_variant
rs1000103200 -- 50,031,147(-) C/G/T intron_variant
rs1000130264 -- 50,097,026(-) A/G intron_variant

Structural Variations from Database of Genomic Variants (DGV) for LINC01599 Gene

Variant ID Type Subtype PubMed ID
esv28926 CNV gain+loss 19812545
nsv564835 CNV gain 21841781

Variation tolerance for LINC01599 Gene

Residual Variation Intolerance Score: 85.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.29; 40.96% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for LINC01599 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
LINC01599

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for LINC01599 Gene

Disorders for LINC01599 Gene

Additional Disease Information for LINC01599

No disorders were found for LINC01599 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for LINC01599 Gene

Publications for LINC01599 Gene

  1. A genome-wide RNAi screen identifies multiple synthetic lethal interactions with the Ras oncogene. (PMID: 19490893) Luo J … Elledge SJ (Cell 2009) 3 58
  2. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K … Sugano S (Genome research 2006) 3 58
  3. The DNA sequence and analysis of human chromosome 14. (PMID: 12508121) Heilig R … Weissenbach J (Nature 2003) 4 58
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3 58

Products for LINC01599 Gene

Sources for LINC01599 Gene

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