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Aliases for LINC01588 Gene

Subcategory (RNA class) for LINC01588 Gene

non-coding RNA

Quality Score for this RNA gene is

3

Aliases for LINC01588 Gene

  • Long Intergenic Non-Protein Coding RNA 1588 2 3 5
  • C14orf182 3 4
  • Chromosome 14 Open Reading Frame 182 2

External Ids for LINC01588 Gene

Previous HGNC Symbols for LINC01588 Gene

  • C14orf182

Previous GeneCards Identifiers for LINC01588 Gene

  • GC14M049981

Summaries for LINC01588 Gene

GeneCards Summary for LINC01588 Gene

LINC01588 (Long Intergenic Non-Protein Coding RNA 1588) is an RNA Gene, and is affiliated with the non-coding RNA class.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for LINC01588 Gene

Genomics for LINC01588 Gene

Regulatory Elements for LINC01588 Gene

Enhancers for LINC01588 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH14F049969 1.7 FANTOM5 Ensembl ENCODE 20.3 +115.8 115840 15.5 PKNOX1 ARNT ARID4B SIN3A FEZF1 ZNF2 YY1 ZNF207 FOS SP5 LINC01588 VCPKMT RNU6-189P RPL36AL ARF6 NEMF DNAAF2 ATP5S RPS29 SOS2
GH14F049867 1.8 FANTOM5 Ensembl ENCODE 16.4 +223.6 223626 4.0 HDGF PKNOX1 SIN3A FEZF1 YY1 SLC30A9 ZNF263 SP3 SP5 JUNB LINC01588 VCPKMT RNU6-189P ARF6 RPL36AL LRR1 SOS2 NEMF MGAT2 LOC105378179
GH14F049985 1.3 Ensembl ENCODE 22 +102.8 102785 8.1 PKNOX1 ATF1 MLX ARID4B DMAP1 ZNF48 YY1 FOS SP5 JUNB LINC01588 RNU6-189P VCPKMT LOC105370485 GC14M050001
GH14F050055 1.8 FANTOM5 Ensembl ENCODE 15.6 +31.6 31582 10.9 HDGF PKNOX1 CREB3L1 WRNIP1 ARID4B SIN3A DMAP1 ZNF2 YY1 ZNF143 VCPKMT LINC01588 POLE2 KLHDC2 RNU6-189P ATP5S RHOQP1 RPS29 SOS2 ARF6
GH14F049959 1.4 FANTOM5 Ensembl ENCODE 18.1 +131.0 130959 4.6 HDGF ELF3 PKNOX1 RAD21 ZNF366 EGR1 RCOR1 ETV6 FOS CREM LINC01588 RNU6-189P VCPKMT LOC100506446 GC14P049956
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around LINC01588 on UCSC Golden Path with GeneCards custom track

Genomic Location for LINC01588 Gene

Chromosome:
14
Start:
49,927,571 bp from pter
End:
50,092,643 bp from pter
Size:
165,073 bases
Orientation:
Minus strand

Genomic View for LINC01588 Gene

Genes around LINC01588 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
LINC01588 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for LINC01588 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for LINC01588 Gene

Proteins for LINC01588 Gene

  • Protein details for LINC01588 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A1A4T8-CN182_HUMAN
    Recommended name:
    Uncharacterized protein encoded by LINC01588
    Protein Accession:
    A1A4T8
    Secondary Accessions:
    • A8MYX4

    Protein attributes for LINC01588 Gene

    Size:
    154 amino acids
    Molecular mass:
    17448 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for LINC01588 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for LINC01588 Gene

Post-translational modifications for LINC01588 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for LINC01588 Gene

Domains & Families for LINC01588 Gene

Protein Domains for LINC01588 Gene

ProtoNet:

Suggested Antigen Peptide Sequences for LINC01588 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with LINC01588: view

No data available for Gene Families and UniProtKB/Swiss-Prot for LINC01588 Gene

Function for LINC01588 Gene

Gene Ontology (GO) - Molecular Function for LINC01588 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with LINC01588: view

Phenotypes for LINC01588 Gene

GenomeRNAi human phenotypes for LINC01588:
genes like me logo Genes that share phenotypes with LINC01588: view

Animal Model Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for LINC01588 Gene

Localization for LINC01588 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for LINC01588 gene
Compartment Confidence
nucleus 3
cytosol 2
extracellular 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for LINC01588 Gene

Pathways & Interactions for LINC01588 Gene

SuperPathways for LINC01588 Gene

No Data Available

Interacting Proteins for LINC01588 Gene

Gene Ontology (GO) - Biological Process for LINC01588 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for LINC01588 Gene

Transcripts for LINC01588 Gene

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for LINC01588 Gene

No ASD Table

Relevant External Links for LINC01588 Gene

GeneLoc Exon Structure for
LINC01588
ECgene alternative splicing isoforms for
LINC01588

Expression for LINC01588 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for LINC01588 Gene

NURSA nuclear receptor signaling pathways regulating expression of LINC01588 Gene:

LINC01588
genes like me logo Genes that share expression patterns with LINC01588: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for LINC01588 Gene

Orthologs for LINC01588 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for LINC01588 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C14orf182 35
  • 97 (a)
OneToOne
Species where no ortholog for LINC01588 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for LINC01588 Gene

ENSEMBL:
Gene Tree for LINC01588 (if available)
TreeFam:
Gene Tree for LINC01588 (if available)

Paralogs for LINC01588 Gene

No data available for Paralogs for LINC01588 Gene

Variants for LINC01588 Gene

Sequence variations from dbSNP and Humsavar for LINC01588 Gene

SNP ID Clin Chr 14 pos Sequence Context AA Info Type
rs10131496 -- 49,988,645(+) AGACA(A/C)AGGAG intron-variant, nc-transcript-variant
rs10131801 -- 49,989,012(+) TTACC(A/G)TCTGT intron-variant
rs10131892 -- 49,989,011(+) GTTAC(C/T)ATCTG intron-variant
rs10133640 -- 50,001,463(+) GCCCC(A/G)GGAGA intron-variant, nc-transcript-variant
rs10134002 -- 49,992,891(+) GAGAA(C/T)AAGAG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for LINC01588 Gene

Variant ID Type Subtype PubMed ID
esv28926 CNV gain+loss 19812545
nsv1270 CNV insertion 18451855

Variation tolerance for LINC01588 Gene

Residual Variation Intolerance Score: 68.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 5.08; 68.97% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for LINC01588 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
LINC01588

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for LINC01588 Gene

Disorders for LINC01588 Gene

Relevant External Links for LINC01588

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
LINC01588

No disorders were found for LINC01588 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for LINC01588 Gene

Publications for LINC01588 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
  2. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3 64
  3. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3 64
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4 64
  5. The DNA sequence and analysis of human chromosome 14. (PMID: 12508121) Heilig R. … Weissenbach J. (Nature 2003) 4 64

Products for LINC01588 Gene

Sources for LINC01588 Gene

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