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Aliases for LINC01587 Gene

Subcategory (RNA class) for LINC01587 Gene

non-coding RNA

Quality Score for this RNA gene is


Aliases for LINC01587 Gene

  • Long Intergenic Non-Protein Coding RNA 1587 2 3 5
  • C4orf6 3 4
  • AC1 3 4
  • Chromosome 4 Open Reading Frame 6 2
  • Expressed In Neuroblastoma 3
  • Protein AC1 4

External Ids for LINC01587 Gene

Previous HGNC Symbols for LINC01587 Gene

  • C4orf6

Summaries for LINC01587 Gene

Entrez Gene Summary for LINC01587 Gene

  • This gene is expressed in neuroblastoma; however, the function of this gene is not yet determined. [provided by RefSeq, Jul 2008]

GeneCards Summary for LINC01587 Gene

LINC01587 (Long Intergenic Non-Protein Coding RNA 1587) is an RNA Gene, and is affiliated with the non-coding RNA class. Diseases associated with LINC01587 include Neuroblastoma.

Additional gene information for LINC01587 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for LINC01587 Gene

Genomics for LINC01587 Gene

GeneHancer (GH) Regulatory Elements for LINC01587 Gene

Promoters and enhancers for LINC01587 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH04I005524 Enhancer 0.7 Ensembl ENCODE 550.8 +0.6 564 1.6 ELK4 RXRA ELK1 POLR2A RCOR1 WT1 NR2F2 GC04P005525 LINC01587 WFS1
GH04I005504 Enhancer 0.2 ENCODE 0.4 -20.0 -19970 0.1 GC04M005485 LINC01587
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around LINC01587 on UCSC Golden Path with GeneCards custom track

Genomic Locations for LINC01587 Gene

Genomic Locations for LINC01587 Gene
3,233 bases
Plus strand

Genomic View for LINC01587 Gene

Genes around LINC01587 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
LINC01587 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for LINC01587 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for LINC01587 Gene

Proteins for LINC01587 Gene

  • Protein details for LINC01587 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Uncharacterized protein encoded by LINC01587
    Protein Accession:
    Secondary Accessions:
    • Q17R65

    Protein attributes for LINC01587 Gene

    93 amino acids
    Molecular mass:
    10499 Da
    Quaternary structure:
    No Data Available

neXtProt entry for LINC01587 Gene

Post-translational modifications for LINC01587 Gene

No Post-translational modifications

No data available for DME Specific Peptides for LINC01587 Gene

Domains & Families for LINC01587 Gene

Protein Domains for LINC01587 Gene


Suggested Antigen Peptide Sequences for LINC01587 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with LINC01587: view

No data available for Gene Families and UniProtKB/Swiss-Prot for LINC01587 Gene

Function for LINC01587 Gene

Phenotypes for LINC01587 Gene

genes like me logo Genes that share phenotypes with LINC01587: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for LINC01587 Gene

Localization for LINC01587 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for LINC01587 gene
Compartment Confidence
extracellular 2
cytosol 2
nucleus 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for LINC01587 Gene

Pathways & Interactions for LINC01587 Gene

SuperPathways for LINC01587 Gene

No Data Available

Interacting Proteins for LINC01587 Gene

Gene Ontology (GO) - Biological Process for LINC01587 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007399 nervous system development TAS 9016955
genes like me logo Genes that share ontologies with LINC01587: view

No data available for Pathways by source and SIGNOR curated interactions for LINC01587 Gene

Drugs & Compounds for LINC01587 Gene

No Compound Related Data Available

Transcripts for LINC01587 Gene

mRNA/cDNA for LINC01587 Gene

(1) REFSEQ mRNAs :
(11) Selected AceView cDNA sequences:
(4) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

Inhibitory RNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for LINC01587 Gene

No ASD Table

Relevant External Links for LINC01587 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for LINC01587 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for LINC01587 Gene

NURSA nuclear receptor signaling pathways regulating expression of LINC01587 Gene:


mRNA Expression by UniProt/SwissProt for LINC01587 Gene:

Tissue specificity: Expressed in neuroblastoma.
genes like me logo Genes that share expression patterns with LINC01587: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for LINC01587 Gene

Orthologs for LINC01587 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for LINC01587 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia C4H4orf6 33
  • 99.28 (n)
Species where no ortholog for LINC01587 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for LINC01587 Gene

Gene Tree for LINC01587 (if available)
Gene Tree for LINC01587 (if available)

Paralogs for LINC01587 Gene

No data available for Paralogs for LINC01587 Gene

Variants for LINC01587 Gene

Sequence variations from dbSNP and Humsavar for LINC01587 Gene

SNP ID Clin Chr 04 pos Variation AA Info Type
rs1000200636 -- 5,524,658(+) C/T genic_upstream_transcript_variant, non_coding_transcript_variant, upstream_transcript_variant
rs1000330185 -- 5,524,660(+) T/C genic_upstream_transcript_variant, non_coding_transcript_variant, upstream_transcript_variant
rs1001092913 -- 5,526,444(+) G/A intron_variant
rs1001252295 -- 5,523,850(+) C/G upstream_transcript_variant
rs1001598994 -- 5,523,750(+) G/C upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for LINC01587 Gene

Variant ID Type Subtype PubMed ID
esv34196 OTHER inversion 12058347
nsv1005173 CNV gain 25217958
nsv522680 CNV gain 19592680
nsv526713 CNV gain 19592680
nsv593480 CNV loss 21841781
nsv593482 CNV loss 21841781

Variation tolerance for LINC01587 Gene

Residual Variation Intolerance Score: 86.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 7.66; 82.87% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for LINC01587 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for LINC01587 Gene

Disorders for LINC01587 Gene

MalaCards: The human disease database

(1) MalaCards diseases for LINC01587 Gene - From: GeneCards

Disorder Aliases PubMed IDs
  • neuroblastoma, susceptibility to
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for LINC01587

genes like me logo Genes that share disorders with LINC01587: view

No data available for UniProtKB/Swiss-Prot and Genatlas for LINC01587 Gene

Publications for LINC01587 Gene

  1. Fluorescent differential display analysis of gene expression in differentiating neuroblastoma cells. (PMID: 9016955) Kito K … Sakaki Y (Gene 1997) 2 3 4 58
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 58
  3. Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3 58
  4. Long interspersed nuclear element-1 (LINE1)-mediated deletion of EVC, EVC2, C4orf6, and STK32B in Ellis-van Creveld syndrome with borderline intelligence. (PMID: 18454448) Temtamy SA … Ruiz-Perez VL (Human mutation 2008) 3 58
  5. Adenylyl cyclase isoform-selective regulation of vascular smooth muscle proliferation and cytoskeletal reorganization. (PMID: 16973907) Gros R … Feldman RD (Circulation research 2006) 22 58

Products for LINC01587 Gene

Sources for LINC01587 Gene

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