Aliases for LINC01587 Gene
Subcategory (RNA class) for LINC01587 Gene
non-coding RNA
Quality Score for this RNA gene is
3
Aliases for LINC01587 Gene
External Ids for LINC01587 Gene
- HGNC: 13716
- Entrez Gene: 10141
- Ensembl: ENSG00000082929
- UniProtKB: Q99440
Previous HGNC Symbols for LINC01587 Gene
- C4orf6
Summaries for LINC01587 Gene
-
This gene is expressed in neuroblastoma; however, the function of this gene is not yet determined. [provided by RefSeq, Jul 2008]
GeneCards Summary for LINC01587 Gene
LINC01587 (Long Intergenic Non-Protein Coding RNA 1587) is an RNA Gene, and is affiliated with the non-coding RNA class. Diseases associated with LINC01587 include Neuroblastoma.
No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for LINC01587 Gene
Genomics for LINC01587 Gene
Regulatory Elements for LINC01587 Gene
Enhancers for LINC01587 Gene
| GeneHancer Identifier | Enhancer Score | Enhancer Sources | Gene-Enhancer Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Gene Targets for Enhancer |
|---|---|---|---|---|---|---|---|---|
| GH04G005524 | 0.9 | Ensembl ENCODE | 0.7 | +0.6 | 565 | 1.6 | ELK4 RAD21 NR2F2 POLR2A ELK1 HNF4G HNF4A WT1 | WFS1 GC04P005525 LINC01587 |
| GH04G005504 | 0.2 | ENCODE | 0.4 | -20.0 | -19970 | 0.1 | GC04M005485 LINC01587 |
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around LINC01587 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Location for LINC01587 Gene
- Chromosome:
- 4
- Start:
- 5,524,569 bp from pter
- End:
- 5,527,801 bp from pter
- Size:
- 3,233 bases
- Orientation:
- Plus strand
Genomic View for LINC01587 Gene
Genes around LINC01587 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 4p16.2 by Ensembl
- 4p16.2 by Entrez Gene
- 4p16.2 by HGNC
LINC01587 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for LINC01587 Gene
Proteins for LINC01587 Gene
-
Protein details for LINC01587 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q99440-CD006_HUMAN
- Recommended name:
- Uncharacterized protein encoded by LINC01587
- Protein Accession:
- Q99440
- Q17R65
Protein attributes for LINC01587 Gene
- Size:
- 93 amino acids
- Molecular mass:
- 10499 Da
- Quaternary structure:
- No Data Available
Post-translational modifications for LINC01587 Gene
Antibody Products
- Novus Biologicals Antibodies for LINC01587
- antibodies-online Antibodies for LINC01587: See all 3
- Search GeneTex for Antibodies for LINC01587
Protein Products
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- antibodies-online Proteins for LINC01587: See all 5
- Search antibodies-online for peptides
- Search GeneTex for Proteins for LINC01587
-
Abcam proteins for LINC01587
No data available for DME Specific Peptides for LINC01587 Gene
Domains & Families for LINC01587 Gene
Protein Domains for LINC01587 Gene
- ProtoNet:
Suggested Antigen Peptide Sequences for LINC01587 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
No data available for Gene Families and UniProtKB/Swiss-Prot for LINC01587 Gene
Function for LINC01587 Gene
Phenotypes for LINC01587 Gene
- GenomeRNAi human phenotypes for LINC01587:
Animal Model Products
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-
-
ViGene Biosciences lentiviral particle packaged cDNA for LINC01587 gene
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CRISPR Products
-
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miRNA Products
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Inhibitory RNA Products
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Clone Products
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-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
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- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Cell Line Products
-
Horizon Cell Lines for LINC01587
-
ViGene Biosciences adenoviral particle packaged cDNA for LINC01587 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for LINC01587 gene
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No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for LINC01587 Gene
Localization for LINC01587 Gene
| Compartment | Confidence |
|---|---|
| extracellular | 2 |
| cytosol | 2 |
| nucleus | 1 |
No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for LINC01587 Gene
Pathways & Interactions for LINC01587 Gene
No Data Available
Interacting Proteins for LINC01587 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0007399 | nervous system development | TAS | 9016955 |
No data available for Pathways by source and SIGNOR curated interactions for LINC01587 Gene
Transcripts for LINC01587 Gene
mRNA/cDNA for LINC01587 Gene
- (1) REFSEQ mRNAs :
- (11) Selected AceView cDNA sequences:
- (4) Ensembl transcripts including schematic representations, and UCSC links where relevant :
CRISPR Products
-
OriGene CRISPR knockouts for LINC01587
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miRNA Products
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Inhibitory RNA Products
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Clone Products
-
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-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Expression for LINC01587 Gene
NURSA nuclear receptor signaling pathways regulating expression of LINC01587 Gene:
LINC01587mRNA Expression by UniProt/SwissProt for LINC01587 Gene:
Q99440-CD006_HUMAN
Tissue specificity:
Expressed in neuroblastoma.
Primer Products
-
OriGene qPCR primer pairs for LINC01587
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for LINC01587 Gene
Orthologs for LINC01587 Gene
This gene was present in the common ancestor of human and chimp.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | C4H4orf6 34 |
|
- Species where no ortholog for LINC01587 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- cow (Bos Taurus)
- dog (Canis familiaris)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- lizard (Anolis carolinensis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- mouse (Mus musculus)
- oppossum (Monodelphis domestica)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- platypus (Ornithorhynchus anatinus)
- rainbow trout (Oncorhynchus mykiss)
- rat (Rattus norvegicus)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
- zebrafish (Danio rerio)
Paralogs for LINC01587 Gene
No data available for Paralogs for LINC01587 Gene
Variants for LINC01587 Gene
| SNP ID | Clin | Chr 04 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1000200636 | -- | 5,524,658(+) | GAGCA(C/T)ATTTT | nc-transcript-variant, upstream-variant-2KB | |
| rs1000330185 | -- | 5,524,660(+) | GCACA(C/T)TTTCA | nc-transcript-variant, upstream-variant-2KB | |
| rs1001092913 | -- | 5,526,444(+) | AAACA(A/G)CAGAC | intron-variant | |
| rs1001252295 | -- | 5,523,850(+) | TGCGG(C/G)ACTAT | upstream-variant-2KB | |
| rs1001598994 | -- | 5,523,750(+) | AACTA(C/G)AAATA | upstream-variant-2KB |
Residual Variation Intolerance Score:
86.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
7.66;
82.87% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for LINC01587 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- LINC01587
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for LINC01587 Gene
Disorders for LINC01587 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| neuroblastoma |
|
|
Search LINC01587 in MalaCards
View complete list of genes associated with diseases
Relevant External Links for LINC01587
- Atlas of Genetics and Cytogenetics in Oncology and Haematology:
- LINC01587
No data available for UniProtKB/Swiss-Prot and Genatlas for LINC01587 Gene
Publications for LINC01587 Gene
- Fluorescent differential display analysis of gene expression in differentiating neuroblastoma cells. (PMID: 9016955) Kito K. … Sakaki Y. (Gene 1997) 2 3 4 64
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
- Long interspersed nuclear element-1 (LINE1)-mediated deletion of EVC, EVC2, C4orf6, and STK32B in Ellis-van Creveld syndrome with borderline intelligence. (PMID: 18454448) Temtamy S.A. … Ruiz-Perez V.L. (Hum. Mutat. 2008) 3 64
- Adenylyl cyclase isoform-selective regulation of vascular smooth muscle proliferation and cytoskeletal reorganization. (PMID: 16973907) Gros R. … Feldman R.D. (Circ. Res. 2006) 22 64
- Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PMID: 15815621) Hillier L.W. … Wilson R.K. (Nature 2005) 4 64
Products for LINC01587 Gene
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- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for LINC01587 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
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- (33) SOURCE
- (34) HomoloGene
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- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
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- (48) BGMUT
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