Free for academic non-profit institutions. Other users need a Commercial license

Aliases for LINC01547 Gene

Subcategory (RNA class) for LINC01547 Gene

non-coding RNA

Quality Score for this RNA gene is

3

Aliases for LINC01547 Gene

  • Long Intergenic Non-Protein Coding RNA 1547 2 3 5
  • C21orf67 3 4
  • C21orf69 3 4
  • Chromosome 21 Open Reading Frame 69 2
  • Chromosome 21 Open Reading Frame 67 2
  • PRED54 3

External Ids for LINC01547 Gene

Previous HGNC Symbols for LINC01547 Gene

  • C21orf69
  • C21orf67

Summaries for LINC01547 Gene

GeneCards Summary for LINC01547 Gene

LINC01547 (Long Intergenic Non-Protein Coding RNA 1547) is an RNA Gene, and is affiliated with the non-coding RNA class.

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for LINC01547 Gene

Genomics for LINC01547 Gene

Regulatory Elements for LINC01547 Gene

Enhancers for LINC01547 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH21G044966 1.8 FANTOM5 Ensembl ENCODE dbSUPER 9.7 -28.9 -28899 4.6 ATF1 BRCA1 YY1 TCF12 GLIS2 GATA2 ZHX2 ZNF592 PPARGC1A SMARCA4 ENSG00000215447 ENSG00000273027 ITGB2 LINC01547 FAM207A ITGB2-AS1 POFUT2 ENSG00000276529
GH21G044909 1.5 Ensembl ENCODE dbSUPER 11.5 +27.1 27069 6.7 HDGF PKNOX1 FOXA2 MLX ARID4B SIN3A YY1 ZNF207 ZNF143 FOS LINC01547 ITGB2 PTTG1IP ITGB2-AS1
GH21G044938 1.4 ENCODE dbSUPER 9.8 -0.6 -568 3.0 MLX CREB3L1 AGO1 DMAP1 YY1 SLC30A9 ZNF143 ZNF263 SP3 NFYC ENSG00000215447 LINC00205 ENSG00000273027 ITGB2-AS1 PWP2 LINC01547 FAM207A ENSG00000276529
GH21G044984 1.4 Ensembl ENCODE dbSUPER 9.4 -45.2 -45167 1.3 MLX AGO1 ARID4B DMAP1 RAD21 DNMT3B ZNF48 RARA SP5 NFYC SSR4P1 ADARB1 LINC00163 LINC01547 FAM207A LINC00165 ENSG00000276529
GH21G044983 1.4 Ensembl ENCODE dbSUPER 9.1 -43.3 -43253 1.6 FOXA2 RAD21 THRB ZNF48 RARA EGR1 HSF1 ZSCAN5C FOS PCBP1 SSR4P1 ADARB1 ITGB2-AS1 LINC01547 FAM207A ENSG00000276529 LINC00163
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around LINC01547 on UCSC Golden Path with GeneCards custom track

Promoters for LINC01547 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000143123 -387 1801 MLX CREB3L1 AGO1 DMAP1 YY1 SLC30A9 ZNF143 ZNF263 SP3 ZNF610

Genomic Location for LINC01547 Gene

Chromosome:
21
Start:
44,932,814 bp from pter
End:
44,939,913 bp from pter
Size:
7,100 bases
Orientation:
Minus strand

Genomic View for LINC01547 Gene

Genes around LINC01547 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
LINC01547 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for LINC01547 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for LINC01547 Gene

Proteins for LINC01547 Gene

  • Protein details for LINC01547 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P58512-CU067_HUMAN
    Recommended name:
    Uncharacterized protein encoded by LINC01547
    Protein Accession:
    P58512
    Secondary Accessions:
    • P58556
    • Q495D3
    • Q495D5

    Protein attributes for LINC01547 Gene

    Size:
    204 amino acids
    Molecular mass:
    21308 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAK60445.1; Type=Erroneous translation; Note=Wrong choice of CDS.; Evidence={ECO:0000305};

    Alternative splice isoforms for LINC01547 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for LINC01547 Gene

Post-translational modifications for LINC01547 Gene

No Post-translational modifications

No data available for DME Specific Peptides for LINC01547 Gene

Domains & Families for LINC01547 Gene

Protein Domains for LINC01547 Gene

ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with LINC01547: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for LINC01547 Gene

Function for LINC01547 Gene

genes like me logo Genes that share phenotypes with LINC01547: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for LINC01547 Gene

Localization for LINC01547 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for LINC01547 gene
Compartment Confidence
endoplasmic reticulum 5
mitochondrion 2
extracellular 1
peroxisome 1
nucleus 1
cytosol 1

Gene Ontology (GO) - Cellular Components for LINC01547 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005783 endoplasmic reticulum IDA 16780588
genes like me logo Genes that share ontologies with LINC01547: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for LINC01547 Gene

Pathways & Interactions for LINC01547 Gene

SuperPathways for LINC01547 Gene

No Data Available

Interacting Proteins for LINC01547 Gene

Gene Ontology (GO) - Biological Process for LINC01547 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for LINC01547 Gene

Drugs & Compounds for LINC01547 Gene

No Compound Related Data Available

Transcripts for LINC01547 Gene

mRNA/cDNA for LINC01547 Gene

Alternative Splicing Database (ASD) splice patterns (SP) for LINC01547 Gene

ExUns: 1a · 1b ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6a · 6b ^ 7
SP1: -
SP2: - - - -
SP3: -
SP4:

Relevant External Links for LINC01547 Gene

GeneLoc Exon Structure for
LINC01547
ECgene alternative splicing isoforms for
LINC01547

Expression for LINC01547 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for LINC01547 Gene

NURSA nuclear receptor signaling pathways regulating expression of LINC01547 Gene:

LINC01547

mRNA Expression by UniProt/SwissProt for LINC01547 Gene:

P58512-CU067_HUMAN
Tissue specificity: Not detected in any tissue tested.
genes like me logo Genes that share expression patterns with LINC01547: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for LINC01547 Gene

Orthologs for LINC01547 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for LINC01547 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C21orf67 35
  • 96 (a)
OneToOne
Species where no ortholog for LINC01547 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for LINC01547 Gene

ENSEMBL:
Gene Tree for LINC01547 (if available)
TreeFam:
Gene Tree for LINC01547 (if available)

Paralogs for LINC01547 Gene

No data available for Paralogs for LINC01547 Gene

Variants for LINC01547 Gene

Sequence variations from dbSNP and Humsavar for LINC01547 Gene

SNP ID Clin Chr 21 pos Sequence Context AA Info Type
rs1000146787 -- 44,939,340(+) TCTAA(A/C)GAACT intron-variant, upstream-variant-2KB
rs1000387360 -- 44,938,670(+) AGCCT(C/T)TGGAG intron-variant, upstream-variant-2KB
rs1000681521 -- 44,933,020(+) CAGGG(A/C)TAGGC downstream-variant-500B
rs1000765341 -- 44,938,135(+) TCTTG(C/T)TGCCT intron-variant, upstream-variant-2KB
rs1000984670 -- 44,937,361(+) CCCAA(A/G)AAATT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for LINC01547 Gene

Variant ID Type Subtype PubMed ID
esv3647138 CNV loss 21293372
nsv834110 CNV loss 17160897

Variation tolerance for LINC01547 Gene

Gene Damage Index Score: 1.48; 28.93% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for LINC01547 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
LINC01547

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for LINC01547 Gene

Disorders for LINC01547 Gene

Relevant External Links for LINC01547

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
LINC01547

No disorders were found for LINC01547 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for LINC01547 Gene

Publications for LINC01547 Gene

  1. From PREDs and open reading frames to cDNA isolation: revisiting the human chromosome 21 transcription map. (PMID: 11707072) Reymond A. … Antonarakis S.E. (Genomics 2001) 2 3 4 22 64
  2. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3 64
  3. A genome-wide RNAi screen identifies multiple synthetic lethal interactions with the Ras oncogene. (PMID: 19490893) Luo J. … Elledge S.J. (Cell 2009) 3 64
  4. Cell array-based intracellular localization screening reveals novel functional features of human chromosome 21 proteins. (PMID: 16780588) Hu Y.H. … Janitz M. (BMC Genomics 2006) 3 64
  5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 64

Products for LINC01547 Gene

Sources for LINC01547 Gene

Content
Loading form....