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Aliases for LINC01547 Gene

Subcategory (RNA class) for LINC01547 Gene

non-coding RNA

Quality Score for this RNA gene is

3

Aliases for LINC01547 Gene

  • Long Intergenic Non-Protein Coding RNA 1547 2 3 5
  • C21orf67 3 4
  • C21orf69 3 4
  • Chromosome 21 Open Reading Frame 69 2
  • Chromosome 21 Open Reading Frame 67 2
  • PRED54 3

External Ids for LINC01547 Gene

Previous HGNC Symbols for LINC01547 Gene

  • C21orf69
  • C21orf67

Summaries for LINC01547 Gene

GeneCards Summary for LINC01547 Gene

LINC01547 (Long Intergenic Non-Protein Coding RNA 1547) is an RNA Gene, and is affiliated with the non-coding RNA class.

Additional gene information for LINC01547 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for LINC01547 Gene

Genomics for LINC01547 Gene

GeneHancer (GH) Regulatory Elements for LINC01547 Gene

Promoters and enhancers for LINC01547 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH21I044938 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE dbSUPER 559.8 -0.6 -567 3 MLX DMAP1 IRF4 YY1 SLC30A9 E2F8 ZNF143 SP3 NFYC ZNF610 LINC01547 FAM207A ENSG00000215447 PWP2 ENSG00000184441 LINC00205 ENSG00000273027 UBE2G2 ITGB2-AS1 TRAPPC10
GH21I044916 Promoter/Enhancer 2.4 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 7.6 +15.3 15299 16.8 HDGF PKNOX1 CLOCK SMAD1 NEUROD1 SIN3A FEZF1 ZBTB7B IRF4 ZNF207 ITGB2 POFUT2 UBE2G2 ENSG00000273027 TRPM2 ENSG00000184441 PTTG1IP ITGB2-AS1 ENSG00000215447 C21orf2
GH21I044909 Enhancer 1.4 Ensembl ENCODE dbSUPER 11.5 +27.1 27068 6.7 HDGF PKNOX1 FOXA2 MLX ARID4B SIN3A YY1 ZNF207 ZNF143 MCM5 UBE2G2 LINC01547 ITGB2 TRPM2 PTTG1IP ITGB2-AS1
GH21I045073 Promoter/Enhancer 2.5 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 6.4 -135.3 -135290 4 HNRNPUL1 PKNOX1 CLOCK SMAD1 FOXA2 ARNT ARID4B NEUROD1 SIN3A ZNF2 SSR4P1 ADARB1 LOC105372836 POFUT2 ENSG00000184441 UBE2G2 ENSG00000215447 COL6A1 PWP2 LINC00315
GH21I044966 Enhancer 1.6 FANTOM5 Ensembl ENCODE dbSUPER 9.7 -28.9 -28899 4.6 ATF1 BRCA1 ETS1 YY1 TCF12 GLIS2 GATA2 ATF7 RXRA ZHX2 ENSG00000273027 ITGB2 LINC01547 FAM207A ITGB2-AS1 POFUT2 ENSG00000276529
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around LINC01547 on UCSC Golden Path with GeneCards custom track

Genomic Locations for LINC01547 Gene

Genomic Locations for LINC01547 Gene
chr21:44,932,814-44,939,913
(GRCh38/hg38)
Size:
7,100 bases
Orientation:
Minus strand
chr21:46,352,729-46,359,828
(GRCh37/hg19)

Genomic View for LINC01547 Gene

Genes around LINC01547 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
LINC01547 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for LINC01547 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for LINC01547 Gene

Proteins for LINC01547 Gene

  • Protein details for LINC01547 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P58512-CU067_HUMAN
    Recommended name:
    Uncharacterized protein encoded by LINC01547
    Protein Accession:
    P58512
    Secondary Accessions:
    • P58556
    • Q495D3
    • Q495D5

    Protein attributes for LINC01547 Gene

    Size:
    204 amino acids
    Molecular mass:
    21308 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAK60445.1; Type=Erroneous translation; Note=Wrong choice of CDS.; Evidence={ECO:0000305};

    Alternative splice isoforms for LINC01547 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for LINC01547 Gene

Post-translational modifications for LINC01547 Gene

No Post-translational modifications

No data available for DME Specific Peptides for LINC01547 Gene

Domains & Families for LINC01547 Gene

Protein Domains for LINC01547 Gene

ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with LINC01547: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for LINC01547 Gene

Function for LINC01547 Gene

genes like me logo Genes that share phenotypes with LINC01547: view

Animal Model Products

Inhibitory RNA Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for LINC01547 Gene

Localization for LINC01547 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for LINC01547 gene
Compartment Confidence
endoplasmic reticulum 5
mitochondrion 2
extracellular 1
peroxisome 1
nucleus 1
cytosol 1

Gene Ontology (GO) - Cellular Components for LINC01547 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005783 endoplasmic reticulum HDA 16780588
genes like me logo Genes that share ontologies with LINC01547: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from the Human Protein Atlas (HPA) for LINC01547 Gene

Pathways & Interactions for LINC01547 Gene

SuperPathways for LINC01547 Gene

No Data Available

Interacting Proteins for LINC01547 Gene

Gene Ontology (GO) - Biological Process for LINC01547 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for LINC01547 Gene

Drugs & Compounds for LINC01547 Gene

No Compound Related Data Available

Transcripts for LINC01547 Gene

mRNA/cDNA for LINC01547 Gene

Inhibitory RNA Products

Alternative Splicing Database (ASD) splice patterns (SP) for LINC01547 Gene

ExUns: 1a · 1b ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6a · 6b ^ 7
SP1: -
SP2: - - - -
SP3: -
SP4:

Relevant External Links for LINC01547 Gene

GeneLoc Exon Structure for
LINC01547
ECgene alternative splicing isoforms for
LINC01547

Expression for LINC01547 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for LINC01547 Gene

NURSA nuclear receptor signaling pathways regulating expression of LINC01547 Gene:

LINC01547

mRNA Expression by UniProt/SwissProt for LINC01547 Gene:

P58512-CU067_HUMAN
Tissue specificity: Not detected in any tissue tested.
genes like me logo Genes that share expression patterns with LINC01547: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for LINC01547 Gene

Orthologs for LINC01547 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for LINC01547 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C21orf67 34
  • 96 (a)
OneToOne
Species where no ortholog for LINC01547 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for LINC01547 Gene

ENSEMBL:
Gene Tree for LINC01547 (if available)
TreeFam:
Gene Tree for LINC01547 (if available)

Paralogs for LINC01547 Gene

No data available for Paralogs for LINC01547 Gene

Variants for LINC01547 Gene

Sequence variations from dbSNP and Humsavar for LINC01547 Gene

SNP ID Clin Chr 21 pos Variation AA Info Type
rs1000146787 -- 44,939,340(-) A/C intron_variant
rs1000387360 -- 44,938,670(-) C/T intron_variant
rs1000681521 -- 44,933,020(-) C/A downstream_transcript_variant
rs1000765341 -- 44,938,135(-) T/C intron_variant
rs1000984670 -- 44,937,361(-) A/G intron_variant

Structural Variations from Database of Genomic Variants (DGV) for LINC01547 Gene

Variant ID Type Subtype PubMed ID
esv3647138 CNV loss 21293372
nsv834110 CNV loss 17160897

Variation tolerance for LINC01547 Gene

Gene Damage Index Score: 1.48; 28.93% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for LINC01547 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
LINC01547

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for LINC01547 Gene

Disorders for LINC01547 Gene

Additional Disease Information for LINC01547

No disorders were found for LINC01547 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for LINC01547 Gene

Publications for LINC01547 Gene

  1. From PREDs and open reading frames to cDNA isolation: revisiting the human chromosome 21 transcription map. (PMID: 11707072) Reymond A … Antonarakis SE (Genomics 2001) 2 3 4 22 58
  2. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T … Vidal M (Cell 2014) 3 58
  3. A genome-wide RNAi screen identifies multiple synthetic lethal interactions with the Ras oncogene. (PMID: 19490893) Luo J … Elledge SJ (Cell 2009) 3 58
  4. Cell array-based intracellular localization screening reveals novel functional features of human chromosome 21 proteins. (PMID: 16780588) Hu YH … Janitz M (BMC genomics 2006) 3 58
  5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 58

Products for LINC01547 Gene

Sources for LINC01547 Gene

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