Free for academic non-profit institutions. Other users need a Commercial license

Aliases for LINC00473 Gene

Subcategory (RNA class) for LINC00473 Gene

non-coding RNA

Quality Score for this RNA gene is

3

Aliases for LINC00473 Gene

  • Long Intergenic Non-Protein Coding RNA 473 2 3 5
  • C6orf176 3 4
  • Chromosome 6 Open Reading Frame 176 2
  • BA142J11.1 3

External Ids for LINC00473 Gene

Previous HGNC Symbols for LINC00473 Gene

  • C6orf176

Previous GeneCards Identifiers for LINC00473 Gene

  • GC06M166337

Summaries for LINC00473 Gene

GeneCards Summary for LINC00473 Gene

LINC00473 (Long Intergenic Non-Protein Coding RNA 473) is an RNA Gene, and is affiliated with the non-coding RNA class.

UniProtKB/Swiss-Prot for LINC00473 Gene

  • May play a role in cAMP-mediated gene transcription.

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for LINC00473 Gene

Genomics for LINC00473 Gene

Regulatory Elements for LINC00473 Gene

Enhancers for LINC00473 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH06G166004 1.7 FANTOM5 Ensembl ENCODE 0.4 -19.0 -19025 4.8 PKNOX1 FOXA2 SIN3A FEZF1 ZNF2 FOS ZNF263 REST TBX21 KAT8 T PRR18 LOC105378117 LINC00473
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around LINC00473 on UCSC Golden Path with GeneCards custom track

Promoters for LINC00473 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000206782 -152 401 TBP INSM2 KLF17 SIN3A RAD21 BRCA1 GLIS2 SCRT2 RCOR1 ZNF391

Genomic Location for LINC00473 Gene

Chromosome:
6
Start:
165,908,802 bp from pter
End:
165,988,048 bp from pter
Size:
79,247 bases
Orientation:
Minus strand

Genomic View for LINC00473 Gene

Genes around LINC00473 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
LINC00473 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for LINC00473 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for LINC00473 Gene

Proteins for LINC00473 Gene

  • Protein details for LINC00473 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A8K010-CF176_HUMAN
    Recommended name:
    Putative transcriptional regulator encoded by LINC00473
    Protein Accession:
    A8K010

    Protein attributes for LINC00473 Gene

    Size:
    186 amino acids
    Molecular mass:
    21118 Da
    Quaternary structure:
    No Data Available

neXtProt entry for LINC00473 Gene

Post-translational modifications for LINC00473 Gene

No Post-translational modifications

No data available for DME Specific Peptides for LINC00473 Gene

Domains & Families for LINC00473 Gene

Gene Families for LINC00473 Gene

Protein Domains for LINC00473 Gene

ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with LINC00473: view

No data available for Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for LINC00473 Gene

Function for LINC00473 Gene

Molecular function for LINC00473 Gene

UniProtKB/Swiss-Prot Function:
May play a role in cAMP-mediated gene transcription.
UniProtKB/Swiss-Prot Induction:
Up-regulated upon activation of cAMP signaling.

Animal Model Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for LINC00473 Gene

Localization for LINC00473 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for LINC00473 Gene

Pathways & Interactions for LINC00473 Gene

SuperPathways for LINC00473 Gene

No Data Available

Interacting Proteins for LINC00473 Gene

Gene Ontology (GO) - Biological Process for LINC00473 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IMP 22108211
genes like me logo Genes that share ontologies with LINC00473: view

No data available for Pathways by source and SIGNOR curated interactions for LINC00473 Gene

Drugs & Compounds for LINC00473 Gene

No Compound Related Data Available

Transcripts for LINC00473 Gene

Unigene Clusters for LINC00473 Gene

Long intergenic non-protein coding RNA 473:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for LINC00473 Gene

No ASD Table

Relevant External Links for LINC00473 Gene

GeneLoc Exon Structure for
LINC00473
ECgene alternative splicing isoforms for
LINC00473

Expression for LINC00473 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for LINC00473 Gene

mRNA differential expression in normal tissues according to GTEx for LINC00473 Gene

This gene is overexpressed in Ovary (x18.8), Fallopian Tube (x5.7), Pituitary (x5.6), and Adrenal Gland (x4.5).

NURSA nuclear receptor signaling pathways regulating expression of LINC00473 Gene:

LINC00473

SOURCE GeneReport for Unigene cluster for LINC00473 Gene:

Hs.31917
genes like me logo Genes that share expression patterns with LINC00473: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for LINC00473 Gene

Orthologs for LINC00473 Gene

Evolution for LINC00473 Gene

ENSEMBL:
Gene Tree for LINC00473 (if available)
TreeFam:
Gene Tree for LINC00473 (if available)

No data available for Orthologs for LINC00473 Gene

Paralogs for LINC00473 Gene

No data available for Paralogs for LINC00473 Gene

Variants for LINC00473 Gene

Sequence variations from dbSNP and Humsavar for LINC00473 Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type
rs1000080891 -- 165,948,132(+) TGTCT(G/T)TGTGT intron-variant
rs1000097565 -- 165,983,242(+) GTGTA(C/T)ACAAT intron-variant
rs1000114542 -- 165,957,676(+) TTATT(A/C)ATGAA intron-variant
rs1000125583 -- 165,950,454(+) TGGAA(A/C)CCCGT intron-variant
rs1000225355 -- 165,965,157(+) CAGAG(C/T)TGTCC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for LINC00473 Gene

Variant ID Type Subtype PubMed ID
esv1164867 CNV insertion 17803354
esv2733159 CNV deletion 23290073
esv2733160 CNV deletion 23290073
esv2733161 CNV deletion 23290073
esv2733163 CNV deletion 23290073
esv2733164 CNV deletion 23290073
esv3571529 CNV loss 25503493
esv3571530 CNV loss 25503493
nsv1112442 CNV deletion 24896259
nsv1117451 CNV tandem duplication 24896259
nsv1129771 CNV tandem duplication 24896259
nsv1146829 CNV deletion 26484159

Relevant External Links for LINC00473 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
LINC00473

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for LINC00473 Gene

Disorders for LINC00473 Gene

Relevant External Links for LINC00473

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
LINC00473

No disorders were found for LINC00473 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for LINC00473 Gene

Publications for LINC00473 Gene

  1. C6orf176: a novel possible regulator of cAMP-mediated gene expression. (PMID: 22108211) Reitmair A. … Wheeler L. (Physiol. Genomics 2012) 2 3 4 64
  2. Networks of Cultured iPSC-Derived Neurons Reveal the Human Synaptic Activity-Regulated Adaptive Gene Program. (PMID: 28052243) Pruunsild P. … Bading H. (Cell Rep 2017) 2 3 64
  3. Non-coding RNA LINC00473 mediates decidualization of human endometrial stromal cells in response to cAMP signaling. (PMID: 26947914) Liang X.H. … Yang Z.M. (Sci Rep 2016) 3 64
  4. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3 64
  5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 4 64

Products for LINC00473 Gene

Sources for LINC00473 Gene

Content
Loading form....