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Aliases for LINC-PINT Gene

Subcategory (RNA class) for LINC-PINT Gene

non-coding RNA

Quality Score for this RNA gene is

3

Aliases for LINC-PINT Gene

  • Long Intergenic Non-Protein Coding RNA, P53 Induced Transcript 2 3 5
  • MKLN1 Antisense RNA 1 (Head To Head) 2 3
  • P53 Induced Noncoding Transcript 2 3
  • LincRNA-Pint 3
  • MKLN1-AS1 3
  • PINT 3

External Ids for LINC-PINT Gene

Previous HGNC Symbols for LINC-PINT Gene

  • MKLN1-AS1

Previous GeneCards Identifiers for LINC-PINT Gene

  • GC07M130632
  • GC07M130941
  • GC07M130882

Summaries for LINC-PINT Gene

GeneCards Summary for LINC-PINT Gene

LINC-PINT (Long Intergenic Non-Protein Coding RNA, P53 Induced Transcript) is an RNA Gene, and is affiliated with the non-coding RNA class. Diseases associated with LINC-PINT include Alexia and Low Compliance Bladder.

Additional gene information for LINC-PINT Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for LINC-PINT Gene

Genomics for LINC-PINT Gene

Regulatory Elements for LINC-PINT Gene

Enhancers for LINC-PINT Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH07H130883 2.1 FANTOM5 Ensembl ENCODE dbSUPER 11.3 +214.3 214268 24 HDGF PKNOX1 FOXA2 MLX ZFP64 ARID4B SIN3A DMAP1 ZNF2 YY1 ENSG00000226380 MKLN1 RNU6-1010P LINC-PINT KLHDC10 GC07P130900 GC07M130884 MIR29B1 GC07M130879
GH07H131185 1.9 FANTOM5 Ensembl ENCODE dbSUPER 12.1 -78.6 -78612 5 PKNOX1 FOXA2 ATF1 ARNT GATA2 ATF7 FOS RUNX3 SP3 JUNB MKLN1 LINC-PINT ENSG00000270953 GC07M131194 GC07M131173
GH07H131006 1.9 FANTOM5 Ensembl ENCODE dbSUPER 11.6 +99.8 99775 7 HDGF PKNOX1 ATF1 ARNT SIN3A ZNF2 ZNF766 GLIS2 ELK1 ZNF143 RNU6-1010P LINC-PINT MIR29A KLHDC10 MKLN1 GC07M131055 GC07M130950
GH07H130908 2 FANTOM5 Ensembl ENCODE dbSUPER 10.4 +194.2 194151 15 HDGF PKNOX1 FOXA2 MLX ARNT ARID4B SIN3A FEZF1 DMAP1 YY1 COPG2 MIR29A RNU6-1010P LINC-PINT MKLN1-AS LINC00513 TMEM209 MKLN1 GC07P130916 PIR43822
GH07H130954 2 FANTOM5 Ensembl ENCODE dbSUPER 10.3 +151.1 151110 8 HDGF PKNOX1 ATF1 ARNT SIN3A ZNF766 ELK1 ZNF143 ZNF207 FOS COPG2 MIR29A TMEM209 RNU6-1010P LINC-PINT MKLN1 GC07M130950 GC07M131055
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around LINC-PINT on UCSC Golden Path with GeneCards custom track

Promoters for LINC-PINT Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000328382 276 1401 HDGF ARID4B SIN3A DMAP1 ZNF2 YY1 CBX5 FOS SP3 ZHX2

Genomic Location for LINC-PINT Gene

Chromosome:
7
Start:
130,877,562 bp from pter
End:
131,110,176 bp from pter
Size:
232,615 bases
Orientation:
Minus strand

Genomic View for LINC-PINT Gene

Genes around LINC-PINT on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
LINC-PINT Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for LINC-PINT Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for LINC-PINT Gene

Proteins for LINC-PINT Gene

Post-translational modifications for LINC-PINT Gene

No Post-translational modifications

No data available for DME Specific Peptides for LINC-PINT Gene

Domains & Families for LINC-PINT Gene

Gene Families for LINC-PINT Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with LINC-PINT: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for LINC-PINT Gene

Function for LINC-PINT Gene

Phenotypes From GWAS Catalog for LINC-PINT Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for LINC-PINT Gene

Localization for LINC-PINT Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for LINC-PINT gene
Compartment Confidence
nucleus 1
cytosol 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for LINC-PINT Gene

Pathways & Interactions for LINC-PINT Gene

SuperPathways for LINC-PINT Gene

No Data Available

Interacting Proteins for LINC-PINT Gene

Gene Ontology (GO) - Biological Process for LINC-PINT Gene

None

No data available for Pathways by source and SIGNOR curated interactions for LINC-PINT Gene

Drugs & Compounds for LINC-PINT Gene

No Compound Related Data Available

Transcripts for LINC-PINT Gene

Alternative Splicing Database (ASD) splice patterns (SP) for LINC-PINT Gene

No ASD Table

Relevant External Links for LINC-PINT Gene

GeneLoc Exon Structure for
LINC-PINT
ECgene alternative splicing isoforms for
LINC-PINT

Expression for LINC-PINT Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for LINC-PINT Gene

genes like me logo Genes that share expression patterns with LINC-PINT: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for LINC-PINT Gene

Orthologs for LINC-PINT Gene

Evolution for LINC-PINT Gene

ENSEMBL:
Gene Tree for LINC-PINT (if available)
TreeFam:
Gene Tree for LINC-PINT (if available)

No data available for Orthologs for LINC-PINT Gene

Paralogs for LINC-PINT Gene

No data available for Paralogs for LINC-PINT Gene

Variants for LINC-PINT Gene

Sequence variations from dbSNP and Humsavar for LINC-PINT Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type
rs1000015539 -- 131,083,037(+) TTTAT(G/T)TTTTT intron-variant
rs1000045421 -- 131,013,246(+) AAGTA(C/T)GGAGG intron-variant
rs1000075030 -- 131,111,643(+) CTTGA(A/C)ATGTA intron-variant, upstream-variant-2KB
rs1000075978 -- 130,949,644(+) AAGTC(A/G)TTTTA intron-variant
rs1000093827 -- 131,033,363(+) AAAGA(C/T)TCAAC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for LINC-PINT Gene

Variant ID Type Subtype PubMed ID
esv2759563 CNV loss 17122850
esv3615031 CNV loss 21293372
esv3891207 CNV gain 25118596
nsv1109915 CNV deletion 24896259
nsv1145161 CNV deletion 24896259
nsv366176 CNV deletion 16902084
nsv507417 OTHER sequence alteration 20534489
nsv521979 CNV loss 19592680
nsv608422 CNV gain 21841781
nsv608423 CNV loss 21841781
nsv831133 CNV loss 17160897

Relevant External Links for LINC-PINT Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
LINC-PINT

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for LINC-PINT Gene

Disorders for LINC-PINT Gene

MalaCards: The human disease database

(2) MalaCards diseases for LINC-PINT Gene - From: DISEASES

Disorder Aliases PubMed IDs
alexia
  • acquired dyslexia
low compliance bladder
  • hyperactivity of bladder
- elite association - COSMIC cancer census association via MalaCards

Relevant External Links for LINC-PINT

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
LINC-PINT
genes like me logo Genes that share disorders with LINC-PINT: view

No data available for UniProtKB/Swiss-Prot and Genatlas for LINC-PINT Gene

Publications for LINC-PINT Gene

  1. Multiple knockout mouse models reveal lincRNAs are required for life and brain development. (PMID: 24381249) Sauvageau M … Rinn JL (eLife 2013) 2 3 60
  2. Pint lincRNA connects the p53 pathway with epigenetic silencing by the Polycomb repressive complex 2. (PMID: 24070194) Marín-Béjar O … Huarte M (Genome biology 2013) 2 3 60
  3. Single-cell analysis of long non-coding RNAs in the developing human neocortex. (PMID: 27081004) Liu SJ … Lim DA (Genome biology 2016) 3 60
  4. TM4SF5-CTD-2354A18.1-miR-4697-3P may play a key role in the pathogenesis of gastric cancer. (PMID: 26531872) Li DF … Nie YQ (Bratislavske lekarske listy 2015) 3 60
  5. The CASC15 Long Intergenic Noncoding RNA Locus Is Involved in Melanoma Progression and Phenotype Switching. (PMID: 26016895) Lessard L … Hoon DSB (The Journal of investigative dermatology 2015) 3 60

Products for LINC-PINT Gene

Sources for LINC-PINT Gene

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