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Aliases for LINC-PINT Gene

Subcategory (RNA class) for LINC-PINT Gene

non-coding RNA

Quality Score for this RNA gene is

3

Aliases for LINC-PINT Gene

  • Long Intergenic Non-Protein Coding RNA, P53 Induced Transcript 2 3 5
  • MKLN1 Antisense RNA 1 (Head To Head) 2 3
  • P53 Induced Noncoding Transcript 2 3
  • LincRNA-Pint 3
  • MKLN1-AS1 3
  • PINT 3

External Ids for LINC-PINT Gene

Previous HGNC Symbols for LINC-PINT Gene

  • MKLN1-AS1

Previous GeneCards Identifiers for LINC-PINT Gene

  • GC07M130632
  • GC07M130941

Summaries for LINC-PINT Gene

GeneCards Summary for LINC-PINT Gene

LINC-PINT (Long Intergenic Non-Protein Coding RNA, P53 Induced Transcript) is an RNA Gene, and is affiliated with the non-coding RNA class. Diseases associated with LINC-PINT include Alexia.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for LINC-PINT Gene

Genomics for LINC-PINT Gene

Regulatory Elements for LINC-PINT Gene

Enhancers for LINC-PINT Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH07F131185 1 FANTOM5 Ensembl ENCODE 12.1 -78.6 -78612 5.8 HDGF PKNOX1 ATF1 ARNT SIN3A GATA2 FOS DEK PAF1 SP3 MKLN1 LINC-PINT ENSG00000270953 GC07M131194 GC07M131173
GH07F131183 0.4 Ensembl 11.8 -73.7 -73725 0.6 ZNF316 POLR2A LINC-PINT MKLN1 GC07M131173 GC07M131194
GH07F131019 0.6 Ensembl ENCODE 11.7 +89.1 89092 3.0 PKNOX1 MTA2 JUNB EBF1 ATF2 RELA TARDBP EED IKZF1 ID3 RNU6-1010P LINC-PINT ENSG00000273489 MKLN1 GC07M131055 GC07M130950
GH07F131006 1.5 FANTOM5 Ensembl ENCODE 11.6 +98.4 98359 10.2 ATF1 PKNOX1 ARNT SIN3A ZNF2 GLIS2 ZNF548 FOS JUNB REST RNU6-1010P LINC-PINT MIR29A KLHDC10 MKLN1 GC07M131055 GC07M130950
GH07F131243 0.9 Ensembl ENCODE 11.4 -134.3 -134311 1.1 ATF1 JUN RAD21 ZNF366 FOS CREM TCF7L2 SMARCE1 MAZ SMARCC1 LINC-PINT MKLN1 MKLN1-AS RPL27P11 GC07M131248
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around LINC-PINT on UCSC Golden Path with GeneCards custom track

Promoters for LINC-PINT Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000634419 1876 6601 HDGF PKNOX1 CREB3L1 WRNIP1 ARID4B SIN3A DMAP1 ZNF2 YY1 CBX5

Genomic Location for LINC-PINT Gene

Chromosome:
7
Start:
130,877,562 bp from pter
End:
131,110,176 bp from pter
Size:
232,615 bases
Orientation:
Minus strand

Genomic View for LINC-PINT Gene

Genes around LINC-PINT on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
LINC-PINT Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for LINC-PINT Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for LINC-PINT Gene

Proteins for LINC-PINT Gene

Post-translational modifications for LINC-PINT Gene

No Post-translational modifications

No data available for DME Specific Peptides for LINC-PINT Gene

Domains & Families for LINC-PINT Gene

Gene Families for LINC-PINT Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with LINC-PINT: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for LINC-PINT Gene

Function for LINC-PINT Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for LINC-PINT Gene

Localization for LINC-PINT Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for LINC-PINT Gene COMPARTMENTS Subcellular localization image for LINC-PINT gene
Compartment Confidence
cytosol 1
nucleus 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for LINC-PINT Gene

Pathways & Interactions for LINC-PINT Gene

SuperPathways for LINC-PINT Gene

No Data Available

Interacting Proteins for LINC-PINT Gene

Gene Ontology (GO) - Biological Process for LINC-PINT Gene

None

No data available for Pathways by source and SIGNOR curated interactions for LINC-PINT Gene

Transcripts for LINC-PINT Gene

Alternative Splicing Database (ASD) splice patterns (SP) for LINC-PINT Gene

No ASD Table

Relevant External Links for LINC-PINT Gene

GeneLoc Exon Structure for
LINC-PINT
ECgene alternative splicing isoforms for
LINC-PINT

Expression for LINC-PINT Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for LINC-PINT Gene

genes like me logo Genes that share expression patterns with LINC-PINT: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for LINC-PINT Gene

Orthologs for LINC-PINT Gene

Evolution for LINC-PINT Gene

ENSEMBL:
Gene Tree for LINC-PINT (if available)
TreeFam:
Gene Tree for LINC-PINT (if available)

No data available for Orthologs for LINC-PINT Gene

Paralogs for LINC-PINT Gene

No data available for Paralogs for LINC-PINT Gene

Variants for LINC-PINT Gene

Sequence variations from dbSNP and Humsavar for LINC-PINT Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type
rs1004677 -- 131,084,072(+) ATTGA(A/C)AAATA intron-variant
rs10085671 -- 131,075,846(+) CTGGT(C/G)GTGAG intron-variant
rs10085869 -- 131,077,395(+) AGAAA(C/T)CTATC intron-variant
rs10085872 -- 131,077,362(+) AAACT(A/G)TTTAG intron-variant
rs10156020 -- 130,891,353(+) CAGAA(A/C)CCAGA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for LINC-PINT Gene

Variant ID Type Subtype PubMed ID
esv2759563 CNV loss 17122850
esv3615031 CNV loss 21293372
esv3891207 CNV gain 25118596
nsv1109915 CNV deletion 24896259
nsv1145161 CNV deletion 24896259
nsv366176 CNV deletion 16902084
nsv507417 OTHER sequence alteration 20534489
nsv521979 CNV loss 19592680
nsv608422 CNV gain 21841781
nsv608423 CNV loss 21841781
nsv831133 CNV loss 17160897

Relevant External Links for LINC-PINT Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
LINC-PINT

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for LINC-PINT Gene

Disorders for LINC-PINT Gene

MalaCards: The human disease database

(1) MalaCards diseases for LINC-PINT Gene - From: DISEASES

Disorder Aliases PubMed IDs
alexia
  • acquired dyslexia
- elite association - COSMIC cancer census association via MalaCards

Relevant External Links for LINC-PINT

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
LINC-PINT
genes like me logo Genes that share disorders with LINC-PINT: view

No data available for UniProtKB/Swiss-Prot and Genatlas for LINC-PINT Gene

Publications for LINC-PINT Gene

  1. Pint lincRNA connects the p53 pathway with epigenetic silencing by the Polycomb repressive complex 2. (PMID: 24070194) MarA-n-BAcjar O. … Huarte M. (Genome Biol. 2013) 2 3 64
  2. Multiple knockout mouse models reveal lincRNAs are required for life and brain development. (PMID: 24381249) Sauvageau M. … Rinn J.L. (Elife 2013) 2 3 64
  3. The CASC15 Long Intergenic Noncoding RNA Locus Is Involved in Melanoma Progression and Phenotype Switching. (PMID: 26016895) Lessard L. … Hoon D.S. (J. Invest. Dermatol. 2015) 3 64
  4. TM4SF5-CTD-2354A18.1-miR-4697-3P may play a key role in the pathogenesis of gastric cancer. (PMID: 26531872) Li D.F. … Nie Y.Q. (Bratisl Lek Listy 2015) 3 64
  5. Germline sequence variants in TGM3 and RGS22 confer risk of basal cell carcinoma. (PMID: 24403052) Stacey S.N. … Stefansson K. (Hum. Mol. Genet. 2014) 3 64

Products for LINC-PINT Gene

Sources for LINC-PINT Gene

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