Aliases for LIN9 Gene
External Ids for LIN9 Gene
Previous GeneCards Identifiers for LIN9 Gene
This gene encodes a tumor suppressor protein that inhibits DNA synthesis and oncogenic transformation through association with the retinoblastoma 1 protein. The encoded protein also interacts with a complex of other cell cycle regulators to repress cell cycle-dependent gene expression in non-dividing cells. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012]
GeneCards Summary for LIN9 Gene
LIN9 (Lin-9 DREAM MuvB Core Complex Component) is a Protein Coding gene. Diseases associated with LIN9 include algoneurodystrophy. Among its related pathways are Developmental Biology and Regulation of PLK1 Activity at G2/M Transition.
UniProtKB/Swiss-Prot for LIN9 Gene
Acts as a tumor suppressor. Inhibits DNA synthesis. Its ability to inhibit oncogenic transformation is mediated through its association with RB1. Plays a role in the expression of genes required for the G1/S transition.