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Aliases for LIMS3L Gene

Aliases for LIMS3L Gene

  • LIM And Senescent Cell Antigen-Like Domains 3-Like 2 3

External Ids for LIMS3L Gene

Previous GeneCards Identifiers for LIMS3L Gene

  • GC02M111204

Summaries for LIMS3L Gene

GeneCards Summary for LIMS3L Gene

LIMS3L (LIM And Senescent Cell Antigen-Like Domains 3-Like) is a Protein Coding gene. An important paralog of this gene is LDB3.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for LIMS3L Gene

Genomics for LIMS3L Gene

Genomic Location for LIMS3L Gene

110,436,614 bp from pter
110,473,075 bp from pter
36,462 bases
Minus strand

Genomic View for LIMS3L Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for LIMS3L Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for LIMS3L Gene

No data available for Regulatory Elements for LIMS3L Gene

Proteins for LIMS3L Gene

  • Protein details for LIMS3L Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    LIM and senescent cell antigen-like-containing domain protein 3-like
    Protein Accession:
    Secondary Accessions:
    • C9K0W2

    Protein attributes for LIMS3L Gene

    117 amino acids
    Molecular mass:
    13251 Da
    Quaternary structure:
    No Data Available

neXtProt entry for LIMS3L Gene

Proteomics data for LIMS3L Gene at MOPED

Post-translational modifications for LIMS3L Gene

No Post-translational modifications

Other Protein References for LIMS3L Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for LIMS3L Gene

Domains for LIMS3L Gene

Protein Domains for LIMS3L Gene


Suggested Antigen Peptide Sequences for LIMS3L Gene

Graphical View of Domain Structure for InterPro Entry



  • Contains 1 LIM zinc-binding domain.
  • Contains 1 LIM zinc-binding domain.
genes like me logo Genes that share domains with LIMS3L: view

No data available for Gene Families for LIMS3L Gene

Function for LIMS3L Gene

Gene Ontology (GO) - Molecular Function for LIMS3L Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
GO:0008270 zinc ion binding IEA --
genes like me logo Genes that share ontologies with LIMS3L: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for LIMS3L Gene

Localization for LIMS3L Gene

Gene Ontology (GO) - Cellular Components for LIMS3L Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005737 cytoplasm --
genes like me logo Genes that share ontologies with LIMS3L: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from COMPARTMENTS for LIMS3L Gene

Pathways for LIMS3L Gene

SuperPathways for LIMS3L Gene

No Data Available

Interacting Proteins for LIMS3L Gene

Selected Interacting proteins: P0CW20-LIM3L_HUMAN for LIMS3L Gene via UniProtKB

Gene Ontology (GO) - Biological Process for LIMS3L Gene


No data available for Pathways by source for LIMS3L Gene

Transcripts for LIMS3L Gene

mRNA/cDNA for LIMS3L Gene

(2) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for LIMS3L Gene

LIM and senescent cell antigen-like domains 3-like:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for LIMS3L Gene

No ASD Table

Relevant External Links for LIMS3L Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for LIMS3L Gene

mRNA expression in normal human tissues for LIMS3L Gene

SOURCE GeneReport for Unigene cluster for LIMS3L Gene Hs.735995

genes like me logo Genes that share expressions with LIMS3L: view

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for LIMS3L Gene

Orthologs for LIMS3L Gene

This gene was present in the common ancestor of animals.

Orthologs for LIMS3L Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia MGC142792 36
  • 15 (a)
(Canis familiaris)
Mammalia -- 36
  • 26 (a)
(Monodelphis domestica)
Mammalia -- 36
  • 15 (a)
(Mus musculus)
Mammalia Lims1 36
  • 27 (a)
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 14 (a)
(Gallus gallus)
Aves -- 36
-- 36
-- 36
-- 36
LIMS1 36
  • 15 (a)
(Anolis carolinensis)
Reptilia -- 36
  • 23 (a)
(Danio rerio)
Actinopterygii lims1 36
  • 15 (a)
lims2 36
  • 15 (a)
fruit fly
(Drosophila melanogaster)
Insecta stck 36
  • 10 (a)
(Caenorhabditis elegans)
Secernentea unc-97 36
  • 7 (a)
sea squirt
(Ciona savignyi)
Ascidiacea CSA.11312 36
  • 12 (a)
Species with no ortholog for LIMS3L:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for LIMS3L Gene

Gene Tree for LIMS3L (if available)
Gene Tree for LIMS3L (if available)

Paralogs for LIMS3L Gene

Paralogs for LIMS3L Gene

(3) SIMAP similar genes for LIMS3L Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with LIMS3L: view

Variants for LIMS3L Gene

Sequence variations from dbSNP and Humsavar for LIMS3L Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type MAF
rs1821574 -- 110,455,705(+) TTTTT(G/T)GAGAC intron-variant
rs2438715 -- 110,442,702(+) TTGTC(A/G)TTGTT intron-variant
rs3975758 -- 110,454,389(+) gtggg(A/G)ggact intron-variant
rs28408973 -- 110,447,488(+) TCTCG(C/T)TCTGT intron-variant
rs28429821 -- 110,447,600(+) CAGGC(A/G)CGTGC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for LIMS3L Gene

Variant ID Type Subtype PubMed ID
nsv874777 CNV Gain 21882294
nsv510884 CNV Complex 20534489
esv2751812 CNV Loss 17911159
dgv4263n71 CNV Gain 21882294
nsv469649 CNV Complex 16826518
nsv508157 CNV Loss 20534489
esv28875 CNV Gain+Loss 19812545

Relevant External Links for LIMS3L Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for LIMS3L Gene

Disorders for LIMS3L Gene

No disorders were found for LIMS3L Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for LIMS3L Gene

Publications for LIMS3L Gene

  1. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PMID: 15815621) Hillier L.W. … Wilson R.K. (Nature 2005) 3 4
  2. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3

Products for LIMS3L Gene

Sources for LIMS3L Gene

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