Free for academic non-profit institutions. Other users need a Commercial license

Aliases for LIMS3 Gene

Aliases for LIMS3 Gene

  • LIM And Senescent Cell Antigen-Like Domains 3 2 3
  • Particularly Interesting New Cys-His Protein 3 3 4
  • Pinch 2 2 3
  • PINCH-3 3 4
  • LIM And Senescent Cell Antigen-Like-Containing Domain Protein 3 3
  • PINCH3 4

External Ids for LIMS3 Gene

Summaries for LIMS3 Gene

GeneCards Summary for LIMS3 Gene

LIMS3 (LIM And Senescent Cell Antigen-Like Domains 3) is a Protein Coding gene. An important paralog of this gene is LDB3.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for LIMS3 Gene

Genomics for LIMS3 Gene

Genomic Location for LIMS3 Gene

Start:
109,898,428 bp from pter
End:
109,925,625 bp from pter
Size:
27,198 bases
Orientation:
Plus strand

Genomic View for LIMS3 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for LIMS3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for LIMS3 Gene

Regulatory Elements for LIMS3 Gene

Proteins for LIMS3 Gene

  • Protein details for LIMS3 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P0CW19-LIMS3_HUMAN
    Recommended name:
    LIM and senescent cell antigen-like-containing domain protein 3
    Protein Accession:
    P0CW19
    Secondary Accessions:
    • B4DPH6
    • Q9HB10

    Protein attributes for LIMS3 Gene

    Size:
    117 amino acids
    Molecular mass:
    13251 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for LIMS3 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for LIMS3 Gene

Proteomics data for LIMS3 Gene at MOPED

Post-translational modifications for LIMS3 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for LIMS3 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for LIMS3 Gene

Domains for LIMS3 Gene

Protein Domains for LIMS3 Gene

InterPro:
ProtoNet:

UniProtKB/Swiss-Prot:

LIMS3_HUMAN
Domain:
  • Contains 1 LIM zinc-binding domain.:
    • P0CW19
genes like me logo Genes that share domains with LIMS3: view

No data available for Gene Families for LIMS3 Gene

Function for LIMS3 Gene

Gene Ontology (GO) - Molecular Function for LIMS3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008270 zinc ion binding IEA --
genes like me logo Genes that share ontologies with LIMS3: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for LIMS3 Gene

Localization for LIMS3 Gene

Subcellular locations from UniProtKB/Swiss-Prot for LIMS3 Gene

Cytoplasm.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for LIMS3 Gene COMPARTMENTS Subcellular localization image for LIMS3 gene
Compartment Confidence
cytosol 3
nucleus 3

Gene Ontology (GO) - Cellular Components for LIMS3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005737 cytoplasm IEA --
genes like me logo Genes that share ontologies with LIMS3: view

Pathways for LIMS3 Gene

SuperPathways for LIMS3 Gene

No Data Available

Interacting Proteins for LIMS3 Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000405165%0d%0a9606.ENSP00000232014%0d%0a
Selected Interacting proteins: ENSP00000405165 for LIMS3 Gene via STRING

Symbol External ID(s) Details
BCL6

Gene Ontology (GO) - Biological Process for LIMS3 Gene

None

No data available for Pathways by source for LIMS3 Gene

Transcripts for LIMS3 Gene

mRNA/cDNA for LIMS3 Gene

Unigene Clusters for LIMS3 Gene

LIM and senescent cell antigen-like domains 3:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for LIMS3 Gene

No ASD Table

Relevant External Links for LIMS3 Gene

GeneLoc Exon Structure for
LIMS3
ECgene alternative splicing isoforms for
LIMS3

Expression for LIMS3 Gene

mRNA expression in normal human tissues for LIMS3 Gene

mRNA differential expression in normal tissues according to GTEx for LIMS3 Gene

This gene is overexpressed in Artery - Aorta (8.2) and Muscle - Skeletal (7.3).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for LIMS3 Gene

SOURCE GeneReport for Unigene cluster for LIMS3 Gene Hs.535619

mRNA Expression by UniProt/SwissProt for LIMS3 Gene

P0CW19-LIMS3_HUMAN
Tissue specificity: Detected in testis.
genes like me logo Genes that share expressions with LIMS3: view

Orthologs for LIMS3 Gene

This gene was present in the common ancestor of animals.

Orthologs for LIMS3 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia MGC142792 37
  • 15 (a)
OneToMany
dog
(Canis familiaris)
Mammalia -- 37
  • 26 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Lims1 37
  • 27 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia -- 37
  • 15 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 37
  • 14 (a)
OneToMany
chicken
(Gallus gallus)
Aves -- 37
ManyToMany
-- 37
ManyToMany
-- 37
ManyToMany
-- 37
ManyToMany
LIMS1 37
  • 15 (a)
ManyToMany
lizard
(Anolis carolinensis)
Reptilia -- 37
  • 23 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii lims1 37
  • 15 (a)
ManyToMany
lims2 37
  • 15 (a)
ManyToMany
fruit fly
(Drosophila melanogaster)
Insecta stck 37
  • 10 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea unc-97 37
  • 7 (a)
OneToMany
sea squirt
(Ciona savignyi)
Ascidiacea CSA.11312 37
  • 12 (a)
OneToMany
Species with no ortholog for LIMS3:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for LIMS3 Gene

ENSEMBL:
Gene Tree for LIMS3 (if available)
TreeFam:
Gene Tree for LIMS3 (if available)

Paralogs for LIMS3 Gene

Paralogs for LIMS3 Gene

Selected SIMAP similar genes for LIMS3 Gene using alignment to 2 proteins:

Pseudogenes.org Pseudogenes for LIMS3 Gene

genes like me logo Genes that share paralogs with LIMS3: view

Variants for LIMS3 Gene

Structural Variations from Database of Genomic Variants (DGV) for LIMS3 Gene

Variant ID Type Subtype PubMed ID
nsv874777 CNV Gain 21882294
nsv510884 CNV Complex 20534489
esv2751812 CNV Loss 17911159
dgv4263n71 CNV Gain 21882294
nsv469649 CNV Complex 16826518
nsv508157 CNV Loss 20534489
esv28875 CNV Gain+Loss 19812545

Relevant External Links for LIMS3 Gene

HapMap Linkage Disequilibrium report
LIMS3

No data available for Sequence variations from dbSNP and Humsavar for LIMS3 Gene

Disorders for LIMS3 Gene

No disorders were found for LIMS3 Gene.

No data available for UniProtKB/Swiss-Prot for LIMS3 Gene

Publications for LIMS3 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  2. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PMID: 15815621) Hillier L.W. … Wilson R.K. (Nature 2005) 3 4
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  4. Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions. (PMID: 15342556) Suzuki Y. … Sugano S. (Genome Res. 2004) 3
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for LIMS3 Gene

Sources for LIMS3 Gene

Back to Top

Content