Aliases for LIM2 Gene
External Ids for LIM2 Gene
This gene encodes an eye lens-specific protein found at the junctions of lens fiber cells, where it may contribute to cell junctional organization. It acts as a receptor for calmodulin, and may play an important role in both lens development and cataractogenesis. Mutations in this gene have been associated with cataract formation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009]
GeneCards Summary for LIM2 Gene
LIM2 (Lens Intrinsic Membrane Protein 2, 19kDa) is a Protein Coding gene. Diseases associated with LIM2 include cataract 19 and cataract, cortical pulverulent, late-onset. GO annotations related to this gene include structural constituent of eye lens.
UniProtKB/Swiss-Prot for LIM2 Gene
Present in the thicker 16-17 nm junctions of mammalian lens fiber cells, where it may contribute to cell junctional organization. Acts as a receptor for calmodulin. May play an important role in both lens development and cataractogenesis