Aliases for LILRA5 Gene
- Leukocyte Immunoglobulin-Like Receptor, Subfamily B (With TM And ITIM Domains), Member 7 3
- Leukocyte Immunoglobulin-Like Receptor Subfamily A Member 5 Soluble 3
- Leukocyte Immunoglobulin-Like Receptor Subfamily A Member 5 3
- Immunoglobulin-Like Transcript 11 Protein 3
- Immunoglobulin-Like Transcript 11 4
- Leukocyte Ig-Like Receptor 9 3
- CD85f Antigen 4
- CD85 3
External Ids for LILRA5 Gene
Previous Symbols for LILRA5 Gene
The protein encoded by this gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family. LIR family members are known to have activating and inibitory functions in leukocytes. Crosslink of this receptor protein on the surface of monocytes has been shown to induce calcium flux and secretion of several proinflammatory cytokines, which suggests the roles of this protein in triggering innate immune responses. This gene is one of the leukocyte receptor genes that form a gene cluster on the chromosomal region 19q13.4. Four alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]
GeneCards Summary for LILRA5 Gene
LILRA5 (Leukocyte Immunoglobulin-Like Receptor, Subfamily A (With TM Domain), Member 5) is a Protein Coding gene. Among its related pathways are Osteoclast differentiation. An important paralog of this gene is KIR2DL4.
UniProtKB/Swiss-Prot for LILRA5 Gene
May play a role in triggering innate immune responses. Does not seem to play a role for any class I MHC antigen recognition.