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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

LHX9 Gene

protein-coding   GIFtS: 50
GCID: GC01P197881

LIM Homeobox 9

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
LIM Homeobox 91 2
LIM Homeobox Protein 92 3
LIM/Homeobox Protein Lhx92

External Ids:    HGNC: 142221   Entrez Gene: 569562   Ensembl: ENSG000001433557   OMIM: 6060665   UniProtKB: Q9NQ693   

Export aliases for LHX9 gene to outside databases

Previous GC identifers: GC01P195608 GC01P193340 GC01P194348 GC01P195169 GC01P194613 GC01P196148 GC01P169037


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for LHX9 Gene:
This gene encodes a member of the LIM homeobox gene family of developmentally expressed transcription factors. The
encoded protein contains a homeodomain and two cysteine-rich zinc-binding LIM domains involved in protein-protein
interactions. The protein is highly similar to a mouse protein that causes gonadal agenesis when inactivated,
suggesting a role in gonadal development. Alternative splicing results in multiple transcript variants. (provided
by RefSeq, Jul 2008)

GeneCards Summary for LHX9 Gene: 
LHX9 (LIM homeobox 9) is a protein-coding gene. Diseases associated with LHX9 include frasier syndrome, and malignant glioma. GO annotations related to this gene include transcription corepressor activity and sequence-specific DNA binding transcription factor activity. An important paralog of this gene is ISL1.

UniProtKB/Swiss-Prot: LHX9_HUMAN, Q9NQ69
Function: Involved in gonadal development (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NT_004487.19  NC_018912.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the LHX9 gene promoter:
         STAT5B   Nkx2-5   E4BP4   E47   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidLHX9 promoter sequence
   Search SABiosciences Chromatin IP Primers for LHX9

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat LHX9


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q31.1   Ensembl cytogenetic band:  1q31.3   HGNC cytogenetic band: 1q31.1

LHX9 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
LHX9 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01P197881:  view genomic region     (about GC identifiers)

Start:
197,881,037 bp from pter      End:
197,904,608 bp from pter
Size:
23,572 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: LHX9_HUMAN, Q9NQ69 (See protein sequence)
Recommended Name: LIM/homeobox protein Lhx9  
Size: 397 amino acids; 43976 Da
Subunit: Interacts with LDB1 and LDB2 (By similarity)
Subcellular location: Nucleus (By similarity)
1 PDB 3D structure from and Proteopedia for LHX9:
2DMQ (3D)    
Secondary accessions: Q5VUE2 Q5VUE3 Q5VUE6 Q86UH2 Q9BYU6 Q9NQ70
Alternative splicing: 4 isoforms:  Q9NQ69-1   Q9NQ69-2   Q9NQ69-3   Q9NQ69-4   

Explore the universe of human proteins at neXtProt for LHX9: NX_Q9NQ69

Explore proteomics data for LHX9 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9NQ69

  • LHX9 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    LHX9 Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_001014434.1  NP_064589.2  

    ENSEMBL proteins: 
     ENSP00000356361   ENSP00000356360   ENSP00000453064   ENSP00000356358   ENSP00000337969  
     ENSP00000356357  

    Human Recombinant Protein Products for LHX9: 
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    Novus Biologicals LHX9 Proteins
    Novus Biologicals LHX9 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for LHX9 

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--

    LHX9 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    LIM: Homeoboxes / LIM class

    4 InterPro protein domains:
     IPR001781 Znf_LIM
     IPR017970 Homeobox_CS
     IPR001356 Homeodomain
     IPR009057 Homeodomain-like

    Graphical View of Domain Structure for InterPro Entry Q9NQ69

    ProtoNet protein and cluster: Q9NQ69

    1 Blocks protein domain: IPB001781 Zn-binding protein

    UniProtKB/Swiss-Prot: LHX9_HUMAN, Q9NQ69
    Similarity: Contains 1 homeobox DNA-binding domain
    Similarity: Contains 2 LIM zinc-binding domains


    LHX9 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: LHX9_HUMAN, Q9NQ69
    Function: Involved in gonadal development (By similarity)

         Gene Ontology (GO): 5/6 molecular function terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003677DNA binding ----
    GO:0003700sequence-specific DNA binding transcription factor activity IEA--
    GO:0003714transcription corepressor activity ISS--
    GO:0005515protein binding ----
    GO:0008270zinc ion binding IEA--
         
    LHX9 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for LHX9:
     Decreased viability with pacli 

         6 MGI mutant phenotypes (inferred from 3 alleles(MGI details for Lhx9):
     cellular  endocrine/exocrine gland  homeostasis/metabolism  nervous system  no phenotypic analysis 
     reproductive system 

    LHX9 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Lhx9tm1Lmgd for LHX9

       inGenious Targeting Laboratory - Custom generated mouse model solutions for LHX9 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for LHX9

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for LHX9 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for LHX9 

    miRNA
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    8 QIAGEN miScript miRNA Assays for microRNAs that regulate LHX9:
    hsa-miR-647 hsa-miR-875-3p hsa-miR-362-3p hsa-miR-329 hsa-miR-802 hsa-miR-590-3p hsa-miR-3941 hsa-miR-1299
    SwitchGear 3'UTR luciferase reporter plasmidLHX9 3' UTR sequence
    Inhib. RNA
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for LHX9


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section




    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for LHX9

    STRING Interaction Network Preview (showing 5 interactants - click image to see 22)

    5/28 Interacting proteins for LHX9 (Q9NQ693 ENSP000003563574) via UniProtKB, MINT, STRING, and/or I2D (see all 28)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    SMAD2Q157963, ENSP000002621604I2D: score=3 STRING: ENSP00000262160
    LDB2O436793, ENSP000003067724I2D: score=2 STRING: ENSP00000306772
    SMURF1Q9HCE73, ENSP000003546214I2D: score=2 STRING: ENSP00000354621
    LDB1Q86U703, ENSP000003924664I2D: score=1 STRING: ENSP00000392466
    PYGO1Q9Y3Y43I2D: score=1 
    About this table

    Gene Ontology (GO): 5/7 biological process terms (GO ID links to tree view) (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006355regulation of transcription, DNA-dependent ----
    GO:0008045motor neuron axon guidance ISS--
    GO:0008283cell proliferation IEA--
    GO:0008584male gonad development IEA--
    GO:0008585female gonad development IEA--

    LHX9 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for LHX9

    Search CenterWatch for drugs/clinical trials and news about LHX9

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for LHX9 gene (2 alternative transcripts): 
    NM_001014434.1  NM_020204.2  

    Unigene Clusters for LHX9:

    LIM homeobox 9
    Hs.442578  [show with all ESTs], Hs.706475  [show with all ESTs]
    Unigene Representative Sequences: NM_020204, AK097614
    8 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000606127 ENST00000475727(uc009wzc.1) ENST00000367391(uc021pgw.1)
    ENST00000367390(uc001gui.1) ENST00000561173 ENST00000367388 ENST00000337020
    ENST00000367387(uc001guk.1)
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat LHX9
    8 QIAGEN miScript miRNA Assays for microRNAs that regulate LHX9:
    hsa-miR-647 hsa-miR-875-3p hsa-miR-362-3p hsa-miR-329 hsa-miR-802 hsa-miR-590-3p hsa-miR-3941 hsa-miR-1299
    SwitchGear 3'UTR luciferase reporter plasmidLHX9 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
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    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat LHX9
    Clone
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    OriGene ORF clones in mouse, rat for LHX9
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    GenScript: all cDNA clones in your preferred vector (see all 2): LHX9 (NM_001014434)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for LHX9
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat LHX9
    Sirion Biotech Customized lentivirus for stable overexpression of LHX9 
                         Customized lentivirus expression plasmids for stable overexpression of LHX9 
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for LHX9
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat LHX9
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat LHX9

    Additional mRNA sequence: AK097614.1 

    4 DOTS entries:

    DT.91952972  DT.99930905  DT.40307381  DT.97795069 

    24/25 AceView cDNA sequences (see all 25):

    AJ277915 BM718821 NM_020204 BM930179 AL522820 CR625363 BM680709 AK097614 
    AY273889 AA316988 AA708227 AL556961 BM683669 AI873441 BM718831 BX389397 
    BX452329 BM683255 BM719324 AJ296272 AA382798 AJ277914 AL522819 AL556960 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for LHX9    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5a · 5b ^ 6a · 6b ^ 7 ^ 8 ^ 9a · 9b · 9c ^ 10 ^ 11 ^ 12
    SP1:                                                  -                                             
    SP2:                    -     -     -                                                               
    SP3:                          -     -                 -                                             
    SP4:                                                                                      -         
    SP5:                                                                                                


    ECgene alternative splicing isoforms for LHX9

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    LHX9 expression in normal human tissues (normalized intensities)      LHX9 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GACAGCCACG
    LHX9 Expression
    About this image


    LHX9 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/21 selected tissues (see all 21) fully expand
     
     Brain (Nervous System)    fully expand to see all 16 entries
             Thalamus
             Midbrain   
     
     Limb (Muscoskeletal System)    fully expand to see all 8 entries
             Limb Muscle Progenitor Cells Forelimb Myotome
             Limb Bud
             limb/hindlimb   
     
     Neural Tube (Nervous System)    fully expand to see all 4 entries
             Telencephalon
     
     Testis (Reproductive System)    fully expand to see all 3 entries
             Gonad Somatic Cells Primitive Gonad
     
     Heart (Cardiovascular System)    fully expand to see all 3 entries
             heart/atrium   

    See LHX9 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for LHX9

    SOURCE GeneReport for Unigene clusters: Hs.442578 Hs.706475
        SABiosciences Custom PCR Arrays for LHX9
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    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat LHX9
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for LHX9

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for LHX9 gene from 7/13 species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Lhx91 , 5 LIM homeobox protein 91, 5 94.72(n)1
    98.68(a)1
      1 (60.82 cM)5
    168761  NM_001042577.11  NP_001036042.11 
     1388251865 
    chicken
    (Gallus gallus)
    Aves LHX91 LIM homeobox 9 88.27(n)
    96.03(a)
      396397  NM_205426.1  NP_990757.1 
    lizard
    (Anolis carolinensis)
    Reptilia LHX96
    Uncharacterized protein
    91(a)
    1 ↔ 1
    GL343211.1(6713-41905)
    African clawed frog
    (Xenopus laevis)
    Amphibia lhx9-A2 LIM homeobox 9 77.85(n)    AJ311711.1 
    zebrafish
    (Danio rerio)
    Actinopterygii BM316258.12   -- 80(n)    BM316258.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta ap6
    apterous
    34(a)
    1 → many
    2R(1593707-1614335)
    worm
    (Caenorhabditis elegans)
    Secernentea ttx-36
    Protein TTX-3, isoform a
    24(a)
    1 → many
    X(11764456-11769378)


    ENSEMBL Gene Tree for LHX9 (if available)
    TreeFam Gene Tree for LHX9 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for LHX9 gene
    ISL12  LMO22  LHX22  LMX1B2  LHX52  LMO12  LHX62  LMO42  
    LHX12  LMX1A2  LMO32  LHX32  LHX42  LHX82  ISL22  
    14 SIMAP similar genes for LHX9 using alignment to 3 protein entries:     LHX9_HUMAN (see all proteins):
    LHX2    LHx4    LHX4    POU6F1    LMO3    ISL2
    LMO4    LMO1    LMO2    LHX8    LHX5    LHX1
    ISL1    LHX6

    LHX9 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/430 SNPs in LHX9 are shown (see all 430)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1426416401,2
    --197879714(+) GTGGGC/TATCGC 1 -- us2k10--------
    rs782024141,2
    C,F--197879787(+) TCCTGG/ACTGCG 1 -- us2k11Minor allele frequency- A:0.03NA 120
    rs125671491,2
    C,F,A,H--197880072(+) GTGGGT/GCAGGC 1 -- us2k18Minor allele frequency- G:0.44WA NA CSA EA 368
    rs2007877931,2
    C--197880169(+) CCCCC-/CACACCC 1 -- us2k10--------
    rs125669531,2
    C,F,H--197880172(+) CCCACC/ACCCCC 1 -- us2k1 tfbs36Minor allele frequency- A:0.08NS CSA 966
    rs679740401,2
    C--197880172(-) GGGGG-/TGTGGG 1 -- us2k11Minor allele frequency- T:0.00NA 2
    rs2004749661,2
    C--197880175(+) CACCC-/TCCCCC 1 -- us2k10--------
    rs1482769031,2
    C--197880321(+) CCTCCC/TTACCG 1 -- us2k10--------
    rs1908673231,2
    --197880400(+) ATGGGC/TAAATA 1 -- us2k10--------
    rs1418183891,2
    --197880541(+) ATCCCA/CTCTAA 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for LHX9 (197881037 - 197904608 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 10 variations for LHX9:    About this table     
    Variant IDTypeSubtypePubMed ID
    dgv56e201CNV Deletion23290073
    esv3513CNV Deletion18987735
    esv2520814CNV Deletion19546169
    esv2143475CNV Deletion18987734
    esv2660965CNV Deletion23128226
    esv1002483CNV Deletion20482838
    esv2721117CNV Deletion23290073
    esv2721095CNV Deletion23290073
    nsv506971CNV Insertion20534489
    esv8658CNV Loss19470904

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 606066    OMIM disorders: --

    3 diseases for LHX9:    About MalaCards
    frasier syndrome    malignant glioma    neuronitis

    1 disease from the University of Copenhagen DISEASES database for LHX9:
    Frasier syndrome

    LHX9 for disorders           About GeneDecksing


    Export disorders for LHX9 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for LHX9 gene, integrated from 9 sources (see all 17):
    (articles sorted by number of sources associating them with LHX9)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (2006)
    2. Absence of mutations involving the LIM homeobox domain gene LHX9 in 46,XY gonadal agenesis and dysgenesis. (PubMed id 11397841)1, 2 Ottolenghi C.... McElreavey K. (2001)
    3. Transcriptional control of axonal guidance and sortin g in dorsal interneurons by the Lim-HD proteins Lhx9 and Lhx1. (PubMed id 19545367)1, 9 Avraham O....Klar A. (2009)
    4. Aberrant methylation and reduced expression of LHX9 i n malignant gliomas of childhood. (PubMed id 19568415)1 Vladimirova V....Pietsch T. (2009)
    5. High-throughput mapping of a dynamic signaling network in mammalian cells. (PubMed id 15761153)1 Barrios-Rodiles M....Wrana J.L. (2005)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
    7. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1 Ota T.... Sugano S. (2004)
    8. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
    9. Lhx9: a novel LIM-homeodomain gene expressed in the developing forebrain. (PubMed id 9880598)1 Retaux S....Besson M.J. (1999)
    10. Initial assessment of human gene diversity and expression patterns based upon 83 million nucleotides of cDNA sequence. (PubMed id 7566098)1 Adams M.D....White O. (1995)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 56956 HGNC: 14222 AceView: LHX9 Ensembl:ENSG00000143355 euGenes: HUgn56956
    ECgene: LHX9 H-InvDB: LHX9

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for LHX9 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for LHX9 gene:
    Search GeneIP for patents involving LHX9

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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