Aliases for LHX8 Gene
Aliases for LHX8 Gene
External Ids for LHX8 Gene
- HGNC: 28838
- Entrez Gene: 431707
- Ensembl: ENSG00000162624
- OMIM: 604425
- UniProtKB: Q68G74
Previous GeneCards Identifiers for LHX8 Gene
- GC01P075306
- GC01P075594
- GC01P073728
Summaries for LHX8 Gene
-
The protein encoded by this gene is a member of the LIM homeobox family of proteins, which are involved in patterning and differentiation of various tissue types. These proteins contain two tandemly repeated cysteine-rich double-zinc finger motifs known as LIM domains, in addition to a DNA-binding homeodomain. This family member is a transcription factor that plays a role in tooth morphogenesis. It is also involved in oogenesis and in neuronal differentiation. This gene is a candidate gene for cleft palate, and it is also associated with odontoma formation. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2012]
GeneCards Summary for LHX8 Gene
LHX8 (LIM Homeobox 8) is a Protein Coding gene. Diseases associated with LHX8 include Odontoma and Cleft Lip/Palate. GO annotations related to this gene include sequence-specific DNA binding. An important paralog of this gene is LHX6.
UniProtKB/Swiss-Prot for LHX8 Gene
-
Transcription factor involved in differentiation of certain neurons and mesenchymal cells.
No data available for CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for LHX8 Gene
Genomics for LHX8 Gene
Regulatory Elements for LHX8 Gene
Enhancers for LHX8 Gene
| GeneHancer Identifier | Enhancer Score | Enhancer Sources | Gene-Enhancer Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Gene Targets for Enhancer |
|---|---|---|---|---|---|---|---|---|
| GH01G075125 | 0.6 | FANTOM5 | 0.7 | -3.1 | -3149 | 0.4 | L3MBTL2 PRDM1 RBFOX2 MGA ZNF507 | SLC44A5 LHX8 ENSG00000261213 |
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around LHX8 on UCSC Golden Path with GeneCards custom track
- Transcription factor binding sites by QIAGEN in the LHX8 gene promoter:
Regulatory Element Products
Genomic Location for LHX8 Gene
- Chromosome:
- 1
- Start:
- 75,128,434 bp from pter
- End:
- 75,161,533 bp from pter
- Size:
- 33,100 bases
- Orientation:
- Plus strand
Genomic View for LHX8 Gene
Genes around LHX8 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 1p31.1 by Ensembl
- 1p31.1 by Entrez Gene
- 1p31.1 by HGNC
LHX8 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for LHX8 Gene
Proteins for LHX8 Gene
-
Protein details for LHX8 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q68G74-LHX8_HUMAN
- Recommended name:
- LIM/homeobox protein Lhx8
- Protein Accession:
- Q68G74
- E9PGE3
Protein attributes for LHX8 Gene
- Size:
- 356 amino acids
- Molecular mass:
- 39301 Da
- Quaternary structure:
- No Data Available
Protein Expression for LHX8 Gene
Post-translational modifications for LHX8 Gene
Other Protein References for LHX8 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
-
Custom Antibody ServicesOriGene Antibodies for LHX8
- Novus Biologicals Antibodies for LHX8
- Invitrogen Antibodies for LHX8
- antibodies-online Antibodies for LHX8: See all 46
- GeneTex LHX8 antibody for LHX8
Protein Products
-
OriGene Purified Proteins for LHX8
- Search Origene for MassSpec and Protein Over-expression Lysates for LHX8
- Origene Custom Protein Services for LHX8
- Novus Biologicals proteins for LHX8
- GeneTex Proteins for LHX8
Assay Products
- antibodies-online Kits for LHX8: See all 19
No data available for DME Specific Peptides for LHX8 Gene
Domains & Families for LHX8 Gene
Gene Families for LHX8 Gene
Protein Domains for LHX8 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for LHX8 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
No data available for UniProtKB/Swiss-Prot for LHX8 Gene
Function for LHX8 Gene
Molecular function for LHX8 Gene
- UniProtKB/Swiss-Prot Function:
- Transcription factor involved in differentiation of certain neurons and mesenchymal cells.
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0003677 | DNA binding | IEA | -- |
| GO:0005515 | protein binding | IPI | 25416956 |
| GO:0008270 | zinc ion binding | IEA | -- |
| GO:0043565 | sequence-specific DNA binding | IEA | -- |
| GO:0046872 | metal ion binding | IEA | -- |
Phenotypes for LHX8 Gene
- MGI mutant phenotypes for LHX8:
- inferred from 5 alleles
- GenomeRNAi human phenotypes for LHX8:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for LHX8
-
-
ViGene Biosciences lentiviral particle packaged cDNA for LHX8 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for LHX8 gene
- Search ViGene Biosciences for LHX8
CRISPR Products
-
OriGene CRISPR knockouts for LHX8
-
Santa Cruz Biotechnology (SCBT) CRISPR for LHX8
- GenScript: Design CRISPR guide RNA sequences for LHX8
miRNA Products
- Search ViGene Biosciences for LHX8
Inhibitory RNA Products
- Origene shRNA, RNAi, and siRNA products in human, mouse, rat for LHX8
- Browse OriGene Inhibitory RNA Products For LHX8
-
ViGene Biosciences ready-to-package AAV shRNAs for LHX8 gene
Clone Products
- Sino Biological Human cDNA Clone for LHX8
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for LHX8
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for LHX8
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Cell Line Products
- ESI BIO PureStem 4D20.8, NCr-fac Progenitor and PureStem 7PEND24, NCr-fac & Meso-prx Progenitor for LHX8
-
Horizon Cell Lines for LHX8
-
ViGene Biosciences adenoviral particle packaged cDNA for LHX8 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for LHX8 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for LHX8 gene
Flow Cytometry Products
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , miRNA , Transcription Factor Targets and HOMER Transcription for LHX8 Gene
Localization for LHX8 Gene
Subcellular locations from UniProtKB/Swiss-Prot for LHX8 Gene
- Nucleus.
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0001674 | female germ cell nucleus | IEA | -- |
| GO:0005634 | nucleus | IEA | -- |
Pathways & Interactions for LHX8 Gene
No Data Available
Interacting Proteins for LHX8 Gene
Selected Interacting proteins:
Q68G74-LHX8_HUMAN
ENSP00000294638
for LHX8 Gene via
MINT
STRING
IID
UniProtKB
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006351 | transcription, DNA-templated | IEA | -- |
| GO:0006355 | regulation of transcription, DNA-templated | IEA | -- |
| GO:0007611 | learning or memory | IEA | -- |
| GO:0008585 | female gonad development | IEA | -- |
| GO:0021879 | forebrain neuron differentiation | IEA | -- |
No data available for Pathways by source and SIGNOR curated interactions for LHX8 Gene
Transcripts for LHX8 Gene
mRNA/cDNA for LHX8 Gene
- (4) REFSEQ mRNAs :
- (2) Additional mRNA sequences :
- (9) Selected AceView cDNA sequences:
- (3) Ensembl transcripts including schematic representations, and UCSC links where relevant :
CRISPR Products
-
OriGene CRISPR knockouts for LHX8
-
Santa Cruz Biotechnology (SCBT) CRISPR for LHX8
- GenScript: Design CRISPR guide RNA sequences for LHX8
miRNA Products
- Search ViGene Biosciences for LHX8
Inhibitory RNA Products
- Origene shRNA, RNAi, and siRNA products in human, mouse, rat for LHX8
- Browse OriGene Inhibitory RNA Products For LHX8
-
ViGene Biosciences ready-to-package AAV shRNAs for LHX8 gene
Clone Products
- Sino Biological Human cDNA Clone for LHX8
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for LHX8
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for LHX8
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Flow Cytometry Products
Expression for LHX8 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Adipose (Muscoskeletal System)
- Lumbar Brown Adipocyte Cells Lumbar Brown Adipose Depot
- Thoracic Committed Brown Preadipocytes Thoracic Brown Adipose Depot
- Lumbar Committed Brown Preadipocytes Lumbar Brown Adipose Depot
- Cervical Brown Adipocyte Cells Cervical Brown Adipose Depot
- Thoracic Brown Adipocyte Cells Thoracic Brown Adipose Depot
-
Brain (Nervous System)
- Anterior Entopeduncular Progenitor Cells Anterior Entopeduncular Area
- Mature Endothelial Cells Blood Brain Barrier
- Medial Ganglionic Eminence Progenitor Cells Medial Ganglionic Eminence
- Endothelial Cells Blood Brain Barrier
- Cerebellum
-
Skeletal Muscle (Muscoskeletal System)
- Mononuclear Myocytes Hyoid Arch Muscles
- Mononuclear Myocytes Mandibular Arch Muscles
- Myoblasts Mandibular Arch Muscles
- Muscle Progenitor Cells Mandibular Arch Muscles
- Myoblasts Hyoid Arch Muscles
-
Neural Tube (Nervous System)
- Anterior Entopeduncular Progenitor Cells Anterior Entopeduncular Area
- Medial Ganglionic Eminence Progenitor Cells Medial Ganglionic Eminence
- Telencephalon
- Diencephalon
-
Tooth (Integumentary System)
- Dental Papilla Cells Dental Papilla
- Dental Mesenchymal Cells Branchial Arch 1
- Dental Follicle Cells Dental Papilla
- Neural Crest (Gastrulation Derivatives)
- Bone (Muscoskeletal System)
-
Head Mesenchyme (Muscoskeletal System)
- Dental Mesenchymal Cells Branchial Arch 1
- Cranial Neural Crest Cells Branchial Arch 1
-
Endothelium (Cardiovascular System)
- Mature Endothelial Cells Blood Brain Barrier
- Endothelial Cells Blood Brain Barrier
- Ovary (Reproductive System)
- Gut Tube (Gastrointestinal Tract)
- Paraxial Mesoderm (Gastrulation Derivatives)
- NULL (Uncategorized)
- Cartilage (Muscoskeletal System)
- Germ Cells (Reproductive System)
- Gonad
mRNA differential expression in normal tissues according to GTEx for LHX8 Gene
This gene is overexpressed in Minor Salivary Gland (x14.3), Brain - Caudate (basal ganglia) (x9.1), Brain - Putamen (basal ganglia) (x7.3), Brain - Nucleus accumbens (basal ganglia) (x6.4), and Brain - Hypothalamus (x5.3).
This gene is overexpressed in Pancreatic juice (64.7).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for LHX8 Gene
NURSA nuclear receptor signaling pathways regulating expression of LHX8 Gene:
LHX8SOURCE GeneReport for Unigene cluster for LHX8 Gene:
Hs.403934Primer Products
-
OriGene qPCR primer pairs for LHX8
No data available for mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for LHX8 Gene
Orthologs for LHX8 Gene
This gene was present in the common ancestor of animals and fungi.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | LHX8 34 35 |
|
||
| cow (Bos Taurus) |
Mammalia | LHX8 34 35 |
|
||
| dog (Canis familiaris) |
Mammalia | LHX8 34 35 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Lhx8 34 |
|
||
| mouse (Mus musculus) |
Mammalia | Lhx8 34 16 35 |
|
||
| platypus (Ornithorhynchus anatinus) |
Mammalia | LHX8 35 |
|
OneToOne | |
| oppossum (Monodelphis domestica) |
Mammalia | LHX8 35 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | LHX8 34 35 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | LHX8 35 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | lhx8 34 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | lhx8a 34 35 |
|
||
| African malaria mosquito (Anopheles gambiae) |
Insecta | AgaP_AGAP006540 34 |
|
||
| fruit fly (Drosophila melanogaster) |
Insecta | Awh 34 35 |
|
||
| worm (Caenorhabditis elegans) |
Secernentea | lim-4 35 |
|
OneToMany | |
| baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | PXL1 37 |
|
|
- Species where no ortholog for LHX8 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Paralogs for LHX8 Gene
Paralogs for LHX8 Gene
(28) SIMAP similar genes for LHX8 Gene using alignment to 3 proteins:
Variants for LHX8 Gene
| SNP ID | Clin | Chr 01 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1000027947 | -- | 75,145,546(+) | CAGGC(A/T)TTTAT | intron-variant | |
| rs1000178763 | -- | 75,138,678(+) | GACCT(A/G)TGAAG | intron-variant | |
| rs1000191102 | -- | 75,129,771(+) | GATGT(G/T)GAAGG | intron-variant | |
| rs1000193912 | -- | 75,182,625(+) | ACCTC(A/G)GCCTC | intron-variant | |
| rs1000251056 | -- | 75,138,345(+) | GTTTC(C/T)TTAAG | intron-variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv2632878 | CNV | deletion | 19546169 |
| nsv1078876 | OTHER | inversion | 25765185 |
| nsv1444 | CNV | insertion | 18451855 |
Residual Variation Intolerance Score:
32.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
2.11;
38.46% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for LHX8 Gene
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for LHX8 Gene
Disorders for LHX8 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| odontoma |
|
|
| cleft lip/palate |
|
|
Search LHX8 in MalaCards
View complete list of genes associated with diseases
Relevant External Links for LHX8
No data available for UniProtKB/Swiss-Prot and Genatlas for LHX8 Gene
Publications for LHX8 Gene
- MTHFR and MSX1 contribute to the risk of nonsyndromic cleft lip/palate. (PMID: 20572854) JagomAogi T. … Metspalu A. (Eur. J. Oral Sci. 2010) 3 46 64
- Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia. (PMID: 20634891) Jugessur A. … Murray J.C. (PLoS ONE 2010) 3 46 64
- Genetic variants in COL2A1, COL11A2, and IRF6 contribute risk to nonsyndromic cleft palate. (PMID: 20672350) Nikopensius T. … Metspalu A. (Birth Defects Res. Part A Clin. Mol. Teratol. 2010) 3 46 64
- Analysis of LHX8 mutation in premature ovarian failure. (PMID: 17624344) Qin Y. … Rajkovic A. (Fertil. Steril. 2008) 3 46 64
- Candidate gene/loci studies in cleft lip/palate and dental anomalies finds novel susceptibility genes for clefts. (PMID: 18978678) Vieira A.R. … Marazita M.L. (Genet. Med. 2008) 3 46 64
Products for LHX8 Gene
- Browse R&D Systems for Antibodies
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- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
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- Custom Antibody ServicesOriGene Antibodies for LHX8
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- Custom Assay Services
- OriGene Purified Proteins for LHX8
- Search Origene for MassSpec and Protein Over-expression Lysates for LHX8
- Origene Custom Protein Services for LHX8
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for LHX8
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- OriGene qPCR primer pairs for LHX8
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- GenScript: Next-day shipping cDNA ORF clone for LHX8 in any vector
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- GenScript: Design CRISPR guide RNA sequences for LHX8
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
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- Plasmid Preparation
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- Sino Biological Transfection Reagents
- Novus Biologicals Antibodies for LHX8
- Novus Biologicals proteins for LHX8
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- ESI BIO PureStem 4D20.8, NCr-fac Progenitor and PureStem 7PEND24, NCr-fac & Meso-prx Progenitor for LHX8
- antibodies-online Antibodies for LHX8: See all 46
- antibodies-online Kits for LHX8: See all 19
- Search antibodies-online for proteins
- Search antibodies-online for peptides
- GeneTex LHX8 antibody for LHX8
- GeneTex Proteins for LHX8
- ViGene Biosciences adenoviral particle packaged cDNA for LHX8 gene
- ViGene Biosciences lentiviral particle packaged cDNA for LHX8 gene
- ViGene Biosciences ready-to-package AAV shRNAs for LHX8 gene
- Search ViGene Biosciences for LHX8
- Horizon Cell Lines for LHX8
- Cyagen custom Knockout/knockin (KOKI) mouse models for LHX8
- VectorBuilder custom plasmid, inducible vectors for LHX8
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for LHX8
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for LHX8 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer