Aliases for LHX4 Gene
External Ids for LHX4 Gene
This gene encodes a member of a large protein family which contains the LIM domain, a unique cysteine-rich zinc-binding domain. The encoded protein is a transcription factor involved in the control of differentiation and development of the pituitary gland. Mutations in this gene cause combined pituitary hormone deficiency 4. [provided by RefSeq, Dec 2010]
GeneCards Summary for LHX4 Gene
LHX4 (LIM Homeobox 4) is a Protein Coding gene. Diseases associated with LHX4 include pituitary hormone deficiency, combined, 4 and lhx4-related combined pituitary hormone deficiency. GO annotations related to this gene include sequence-specific DNA binding transcription factor activity and sequence-specific DNA binding. An important paralog of this gene is LHX6.
UniProtKB/Swiss-Prot for LHX4 Gene
May play a critical role in the development of respiratory control mechanisms and in the normal growth and maturation of the lung.