Aliases for LHX1 Gene
External Ids for LHX1 Gene
Previous GeneCards Identifiers for LHX1 Gene
This gene encodes a member of a large protein family which contains the LIM domain, a unique cysteine-rich zinc-binding domain. The encoded protein is a transcription factor important for the development of the renal and urogenital systems. This gene is a candidate for Mayer-Rokitansky-Kuster-Hauser syndrome, a disorder characterized by anomalies in the female genital tract. [provided by RefSeq, Dec 2010]
GeneCards Summary for LHX1 Gene
LHX1 (LIM Homeobox 1) is a Protein Coding gene. Diseases associated with LHX1 include Chromosome 17Q12 Deletion Syndrome and Mayer-Rokitansky-Kuster-Hauser Syndrome. Among its related pathways are Neural Crest Differentiation. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and transcription corepressor activity. An important paralog of this gene is LHX5.
UniProtKB/Swiss-Prot for LHX1 Gene
Potential transcription factor. May play a role in early mesoderm formation and later in lateral mesoderm differentiation and neurogenesis.