Aliases for LHB Gene
External Ids for LHB Gene
Previous GeneCards Identifiers for LHB Gene
This gene is a member of the glycoprotein hormone beta chain family and encodes the beta subunit of luteinizing hormone (LH). Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. LH is expressed in the pituitary gland and promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids. The genes for the beta chains of chorionic gonadotropin and for luteinizing hormone are contiguous on chromosome 19q13.3. Mutations in this gene are associated with hypogonadism which is characterized by infertility and pseudohermaphroditism. [provided by RefSeq, Jul 2008]
GeneCards Summary for LHB Gene
LHB (Luteinizing Hormone Beta Polypeptide) is a Protein Coding gene. Diseases associated with LHB include Hypogonadotropic Hypogonadism 23 Without Anosmia and Tendinitis. Among its related pathways are Apoptotic Pathways in Synovial Fibroblasts and Peptide hormone metabolism. Gene Ontology (GO) annotations related to this gene include receptor binding and hormone activity. An important paralog of this gene is CGB3.
UniProtKB/Swiss-Prot for LHB Gene
Promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids.